Clinical Trials on Diagnoses That Require Stem Cell Transplant

Total 222 results

Assistance Publique - Hôpitaux de Paris

Active, not recruiting

To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids (MTX-aGVHD)

Stem Cell Transplant Complications | GVHD, Acute | GVH - Graft Versus Host Reaction | Allogeneic Disease

France
Gruppo Italiano Trapianto di Midollo Osseo

Completed

Survey of Severe Infections by Gram Negative Bacteria in Patients Submitted to Stem Cell Transplant (GITMO-SIGNB)

Gram-Negative Bacterial Infections | Complications of Organ Transplant Stem Cells

Italy
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma

Classic Hodgkin Lymphoma | Autologous Stem Cell Transplant
University of Kansas Medical Center
Millennium Pharmaceuticals, Inc.

Completed

A Safety Study Looking at the Combination of Velcade and G-CSF in Patients With Myeloma or Lymphoma

Autologous Transplant | Malignant Lymphoma, Stem Cell Type

United States
University of Calgary

Recruiting

Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor (Sickle-AID)

Sickle Cell Disease | Pure Red Cell Aplasia | Stem Cell Transplant Complications | Red Blood Cell Disorder

Canada
Mount Sinai Hospital, Canada
Princess Margaret Hospital, Canada

Active, not recruiting

Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy

Hypoxia | Hematologic Malignancy | Immunocompromised | Post Hematopoietic Stem Cell Transplant | Pulmonary Infiltrates

Canada
yasmeen magdi sholkamy

Unknown

Prevalence of Chronic Oral Graft Versus Host Disease Risk Factors in Pediatric Patients

Oral Disease | Pediatric Disorder | Stem Cell Transplant Complications | Graft-versus-host-disease
Assistance Publique - Hôpitaux de Paris
GIRCI Ile de France

Not yet recruiting

Prevention of C.Difficile Infections With Oral Vancomycine in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant (VANCALLO)

Stem Cell Transplant Complications | Clostridium Difficile Infections
Mari Dallas

Recruiting

T Cell Therapy of Opportunistic Cytomegalovirus Infection

Cytomegalovirus Infections | Opportunistic Infections | Hematopoietic Stem Cell Transplant

United States
Hackensack Meridian Health

Completed

Tandem Auto Stem Cell Transplant With Melphalan Followed by Melphalan and Bortezomib in Patients With Multiple Myeloma ((Mel/MelVel))

Multiple Myeloma | Auto Stem Cell Transplant

United States
M.D. Anderson Cancer Center

Completed

Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide

Leukemia | Hematologic Malignancies | Blood Stem Cell Transplant Failure

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Administration of Rapidly Generated Multivirus-specific Cytotoxic T-Lymphocytes (VIRAGE)

Epstein-Barr Virus Infections | Stem Cell Transplant | Cytomegalovirus Infections | Adenovirus Infection

United States
Dana-Farber Cancer Institute

Recruiting

Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

Multiple Myeloma | Stem Cell Transplant Complications

United States
University of Arizona

Active, not recruiting

The TOTOM Trial: Tai Chi to Optimize Transplant Outcomes for Multiple Myeloma

Multiple Myeloma | Stem Cell Transplant Complications

United States
University of California, San Francisco
American Society of Clinical Oncology

Completed

Randomized Study of Digital Life Coaching in Myeloma Patients Undergoing Transplantation

Multiple Myeloma | Stem Cell Transplant

United States
Peking University People's Hospital

Not yet recruiting

Multivirus-specific T Cells in the Treatment of Refractory CMV and/or EBV Infection After Allo-HSCT

Stem Cell Transplant | CMV Infection | EBV Infection
Hospital Universitario Dr. Jose E. Gonzalez

Unknown

Low Dose Plerixafor Plus G-CSF in Mobilizing Stem Cells for Autologous Peripheral Blood Transplantation

Lymphoma, Non-Hodgkin | Myeloma | Lymphoma, Hodgkin | Stem Cell Transplant Complications

Mexico
Gruppo Italiano Trapianto di Midollo Osseo
Azienda Ospedaliero-Universitaria Careggi

Completed

Novel Drugs After Allo-HSCT in Patients With Multiple Myeloma (NEW_ALL_MM)

Multiple Myeloma | Stem Cell Transplant

Italy
Takeda

Active, not recruiting

A Study of Oral Ixazomib Citrate (MLN9708) Maintenance Therapy in Participants With Multiple Myeloma Following Autologous Stem Cell Transplant

Multiple Myeloma | Autologous Stem Cell Transplant

United States, Spain, Australia, Czechia, Hungary, Taiwan, Italy, Denmark, Portugal, Singapore, Israel, Canada, France, Belgium, United Kingdom, Germany, Japan, Austria, Netherlands, Korea, Republic of, Poland, Greece, Colombia, Sweden, South Africa and more
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Dara-RVd Induction for Newly Diagnosed Multiple Myeloma With Autologous Stem Cell Transplantation

Multiple Myeloma | Newly Diagnosed Multiple Myeloma | Autologous Stem Cell Transplantation

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Fertility Preservation in Women Who Will Have Gonadotoxic Therapy or Hematopoetic Stem Cell Transplantation, and in Women With Sickle Cell Disease

Stem Cell Transplant | Aplastic Anemia | Hemoglobin

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Liver Stiffness Measurement Predicts VOD/SOS Development (ELASTOVOD ITALIAN MULTICENTRIC STUDY) (ELASTOVOD)

Stem Cell Transplant Complications | Sinusoidal Obstruction Syndrome | Veno Occlusive Disease, Hepatic

Italy
Instituto Brasileiro de Controle do Cancer

Not yet recruiting

Efficacy of N-acetylcysteine Versus Placebo as Prophylaxis of Sinusoidal Obstruction Syndrome in Patients Undergoing Hematopoietic Stem Cell Transplantation (ALISON)

Hematopoietic Stem Cell Transplant (HSCT) | Sinusoidal Obstruction Syndrome (SOS)

Brazil
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; Institut... and other collaborators

Completed

Ontogeny of MAIT Cells in Neonates and Hematopoietic Stem Cell Transplant Recipients (NEOMAIT)

Term and Preterm Neonates (24-41 Weeks Gestational Age) | Hematopoietic Stem Cell Transplant Recipient Children

France
Sumithira Vasu
Kiadis Pharma

Recruiting

Trial Testing Safety of IL-21 NK Cells for Induction of R/R AML

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Blasts 10 Percent or More of Bone Marrow Nucleated Cells | Allogeneic Stem Cell Transplant Recipient

United States
Intergroupe Francophone du Myelome

Completed

Assessment of Mobilization Cost for Multiple Myeloma Using 2 Different Mobilization Strategies (MOZOBIL)

Multiple Myeloma | Blood Stem Cell Transplant Failure

France
Sanofi

Completed

Mobilization of Stem Cells With AMD3100 (Plerixafor) in Combination With G-CSF in Multiple Myeloma Patients

Autologous Haematopoietic Stem Cell Transplant

China
Mayo Clinic

Recruiting

Determining The Impact Of Distance Reiki On Patient Reported QOL And Immunity Among Multiple Myeloma Patients

Multiple Myeloma | Autologous Stem Cell Transplant

United States
Prof. Tobias Feuchtinger
European Commission; Simbec-Orion Group Ltd, Merthyr Tydfil, UK; Miltenyi Biotec... and other collaborators

Recruiting

Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections (TRACE)

CMV Infection | EBV Infection | Stem Cell Transplant Complications | AdV Infection

Belgium, Spain, France, Germany, Italy, Netherlands
Gruppo Italiano Trapianto di Midollo Osseo
Azienda Policlinico Umberto I

Completed

Prospective Survey of CMV, Herpesviruses Infections and Diseases in Allo-HSCT (CYTOALLOSURVEY)

Hematologic Diseases | Stem Cell Transplant Complications | Cytomegalovirus Viremia | Herpesvirus Infection

Italy
Sheba Medical Center

Unknown

Fecal Microbiota Transplantation for Steroid Resistant and Steroid Dependent Gut Acute Graft Versus Host Disease

Stem Cell Transplant Complications | Fecal Microbiota Transplantation | Graft Versus Host Disease, Acute

Israel
Leland Metheny

Not yet recruiting

Preemptive Infusion of Donor Lymphocytes Depleted of TCR + T Cells + CD19+ B Cells Following ASCT

Lymphoproliferative Disorders | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Allogeneic Stem Cell Transplant Candidate | Acute Myeloid/Lymphoblastic Leukemia

United States
Fuda Cancer Hospital, Guangzhou
Guangzhou Four-Leaf Clover HealthTech Co., Ltd.

Withdrawn

Very Small Embryonic-like Stem Cells for Ovary

Premature Ovarian Failure | Stem Cell Transplant Complications

China
St. Petersburg State Pavlov Medical University

Active, not recruiting

PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT (PTCyRuxo)

Acute Myeloid Leukemia | Acute Lymphoid Leukemia | Stem Cell Transplant Complications | Graft-versus-host-disease

Russian Federation
Grupo Español de Linfomas y Transplante Autólogo...

Completed

Bendamustine, Cytarabine, Etoposide and Melphalan (BeEAM) as Conditioning for Autologous Stem Cell Transplant (ASCT) in Aggressive Non Hodgkin's Lymphoma (NHL). (BeEAM2010-01)

Bendamustine | Conditioning Therapy | Autologous Stem Cell Transplant | Aggressive Non Hodgkin's Lymphoma

Spain
Masonic Cancer Center, University of Minnesota

Terminated

Influenza Vaccine Post Allogeneic Transplant

Hematologic Malignancy | Hematopoietic Stem Cell Transplant

United States
Alberta Health Services, Calgary
Alberta Cancer Foundation; University of Victoria

Recruiting

Early Integration of Palliative and Supportive Care in Cellular Therapy (PALS_CT)

Lymphoma | Leukemia | Multiple Myeloma | Blood Cancer | Stem Cell Transplant Complications | Chimeric Antigen Receptor T-cell Therapy

Canada
University of Erlangen-Nürnberg Medical School

Terminated

The Influence of TaKeTiNa Music Therapy, Traditional Chinese Acupuncture and Clown Theatrical Performance on Quality of Life and the Therapeutic Process of Patients Undergoing Allogenic Stem Cell Transplantation (TriCAM)

Depression | Quality of Life | Leukemia | Graft-Versus-Host Disease | Stem Cell Transplant Complications | Hematological Neoplasm

Germany
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Plasma Cell Leukemia | Loss of Chromosome 17p | Autologous Hematopoietic Stem Cell Transplant Recipient

United States
Pfizer

Withdrawn

Study of RV521 in the Treatment of Adult Subjects Who Have Undergone HCT With an URTI With RSV (REVIRAL2)

Lower Resp Tract Infection | RSV Infection | Stem Cell Transplant Complications
University of California, San Francisco

Withdrawn

Sirolimus Prophylaxis for aGVHD in TME SCID

Severe Combined Immunodeficiency | Stem Cell Transplant | Transplacental Maternal Engraftment

United States
Fred Hutchinson Cancer Center

Active, not recruiting

Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases

Myasthenia Gravis | Neuromyelitis Optica | Autoimmune Disease | Chronic Inflammatory Demyelinating Polyneuropathy | Lambert Eaton Myasthenic Syndrome | Cerebellar Degeneration | Stiff Person Syndrome | Opsoclonus Myoclonus Syndrome | Neurologic Autoimmune Disease | Autologous Transplant Autoimmune | Multiple... and other conditions

United States
Children's Hospital Medical Center, Cincinnati

Recruiting

Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant (HSCT)

Bronchiolitis Obliterans (BO) | Hematopoietic Stem Cell Transplant (HSCT)

United States
Assistance Publique - Hôpitaux de Paris
GlaxoSmithKline

Terminated

Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre Transplantation (RESPPEDOBS)

Bronchiolitis Obliterans | Respiratory Disease | Stem Cell Transplant Complications

France
Randy Windreich

Completed

Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS) | Hematopoietic Stem Cell Transplant (HSCT)

United States
National Cancer Institute (NCI)

Completed

Montelukast to Treat Bronchiolitis Obliterans

Chronic Graft Versus Host Disease | Stem Cell Transplant | Bronchiolitis Obliterans | Leukotriene | Montelukast

United States
iOMEDICO AG

Active, not recruiting

Non-interventional Study to Evaluate Patient and Healthcare Provider Satisfaction of Daratumumab Use in the Treatment of First-line Daratumumab, Lenalidomide, Dexamethasone (DRd) Multiple Myeloma Patients in Germany Depending on Application Route (sc or iv) (MYLENE)

Multiple Myeloma | Patient Satisfaction | Personal Satisfaction | Newly Diagnosed | Transplant Ineligible | Patient Preference

Germany
Atara Biotherapeutics

Recruiting

A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases

Lymphoproliferative Disorders | Leiomyosarcoma | Stem Cell Transplant Complications | Solid Organ Transplant Complications | Epstein-Barr Virus (EBV)-Associated Diseases | EBV+ Post-transplant Lymphoproliferative Disease (EBV+ PTLD) | Allogeneic Hematopoietic Cell Transplant | EBV+ Sarcomas | EBV+ Lymphoproliferative... and other conditions

United States, Austria, Belgium, France, Italy, Spain, United Kingdom
Massachusetts General Hospital
The Leukemia and Lymphoma Society

Recruiting

Psychosocial Mobile App for Chronic Graft-Versus-Host Disease

Allogeneic Stem Cell Transplant | Chronic Graft-Versus-Host Disease

United States
Zambon SpA

Terminated

A Safety Study of Liposomal Cyclosporine A to Treat Bronchiolitis After Hematopoietic Transplant (BOSTON-4) (BOSTON-4)

Stem Cell Transplant Complications | GVHD, Chronic | Bronchiolitis Obliterans Syndrome (BOS)

Spain, France, Germany

Clinical Trials on Diagnoses That Require Stem Cell Transplant

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