Clinical Trials on Digestive System Abnormalities in United Kingdom

Total 81732 results

King's College Hospital NHS Trust

Unknown

RCT of Steroids Following Kasai Portoenterostomy for Biliary Atresia.

Biliary Atresia

United Kingdom
Alder Hey Children's NHS Foundation Trust

Recruiting

Long-term Qualitative and Quantitative Outcomes of Children With Hirschsprung's Disease and Anorectal Malformations (ALOHA)

Anorectal Malformations | Hirschsprung Disease

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
National Institute for Health Research, United Kingdom

Recruiting

Swallowing, Feeding and Eating in Children Born With Oesophageal Atresia/Trache-oesophageal Fistula (OA/TOF) (SaFE)

Esophageal Atresia With Tracheoesophageal Fistula

United Kingdom
Birmingham Women's and Children's NHS Foundation...

Not yet recruiting

Use of Indocyanine Green During Primary Repair of Oesophageal Atresia and Distal Tracheo-oesophageal Fistula (iTOF)

Tracheo-Esophageal Fistula With Atresia of Esophagus

United Kingdom
Naved Alizai
Baxter Healthcare Corporation

Unknown

Trail to Investigate the Effectiveness of CoSeal in Reducing Adhesions Following the Kasai Hepatoportoenterostomy for Biliary Atresia (CoSRCT)

Biliary Atresia

United Kingdom
King's College London
University College Hospital, Ibadan; Lagos State University; Obafemi Awolowo... and other collaborators

Completed

Children's Surgery in Sub-Saharan Africa (PaedSurgAfrica)

Inguinal Hernia | Appendicitis | Gastroschisis | Intussusception | Anorectal Malformation

United Kingdom
King's College London

Completed

Management and Outcomes of Congenital Anomalies in Low-, Middle- and High-Income Countries

Congenital Diaphragmatic Hernia | Gastroschisis | Intestinal Atresia | Hirschsprung Disease | Oesophageal Atresia | Anorectal Malformation | Exomphalos

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases (CO2)

Congenital Diaphragmatic Hernia | Esophageal Atresia With Tracheo-esophageal Fistula

United Kingdom
Imperial College London

Completed

Initial Experience With a New Laparoscopic Based Robotically Assisted Surgical System for Cholecystectomy

Cholecystitis | Biliary Colic

United Kingdom
University Hospital Southampton NHS Foundation...
University of Southampton; NeoKare Nutrition Ltd

Recruiting

Neokare Safety and Tolerability Assessment in Neonates With GI Problems

Anorectal Malformations | Gastroschisis | Hirschsprung Disease | Volvulus | Meconium Ileus | Intestinal Perforation | Preterm | NEC | Cows Milk Allergy | Atresia, Intestinal | Exomphalos

United Kingdom
Enterprise Therapeutics Ltd

Completed

A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects

Healthy

United Kingdom
Intercept Pharmaceuticals

Terminated

Obeticholic Acid in Pediatric Subjects With Biliary Atresia (CARE)

Biliary Atresia

Israel, United Kingdom, Poland, Belgium, France, Germany, Italy, Netherlands, Spain
Institute of Child Health

Completed

Double Blind Randomized Study Into the Efficacy of Codeine Phosphate Analgesia After Cleft Palate Repair in Infants

Cleft Palate Repair

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Cleft Palate Surgical Simulator: Improvement in Surgical Trainees' Knowledge and Confidence.

Cleft Palate Lip

United Kingdom
Mirum Pharmaceuticals, Inc.

Completed

Evaluation of Maralixibat in Biliary Atresia Response Post-Kasai (EMBARK)

Biliary Atresia

United States, United Kingdom, China, Taiwan, Germany, Poland, Singapore, Vietnam
Royal Brompton & Harefield NHS Foundation Trust
University Hospital, Basel, Switzerland; Bioxydyn Ltd, Manchester

Unknown

MRI in Cystic Fibrosis and Primary Ciliary Dyskinesia

Cystic Fibrosis | Primary Ciliary Dyskinesia

United Kingdom
University of Dundee

Recruiting

Bronchiectasis Alpha-1 Augmentation Trial- Modulating Airway Neutrophil Function (BATMAN)

Bronchiectasis Adult

United Kingdom
Nottingham University Hospitals NHS Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; Manchester... and other collaborators

Recruiting

A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF (CARDS-CF)

Respiratory Tract Diseases | Lung Diseases | Cystic Fibrosis | Genetic Disease | Digestive System Disease | Pancreatic Disease

United Kingdom
Manchester University NHS Foundation Trust
University of Oxford; University of Liverpool

Completed

Timing of Stoma Closure in Neonates (ToSCiN)

Premature Birth | Enterocolitis, Necrotizing | Gastroschisis | Meconium Ileus | Bowel Obstruction | Atresia; Bowel | Perforation Bowel

United Kingdom
Albireo

Completed

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases

United Kingdom
Imperial College London

Completed

Osteoprotegerin (OPG) in Induced Chronic Obstructive Pulmonary Disease (COPD) Sputum

Pulmonary Disease, Chronic Obstructive

United Kingdom
Queen Mary University of London

Withdrawn

Clinical Trial of Zirconia and Metal Adhesive Bridges

Missing Teeth

United Kingdom
GlaxoSmithKline

Completed

Repeat Dose Study in Male Healthy Volunteer Smokers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Mirum Pharmaceuticals, Inc.

Completed

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS) (IMAGINE)

Alagille Syndrome

United Kingdom
Mirum Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Alagille Syndrome (IMAGO)

Alagille Syndrome

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Methods of Providing Information Prior to an Alveolar Bone Graft

Cleft Lip and Palate

United Kingdom
Research and Education in Dentistry

Unknown

Vertical Augmentation With Osteon at Dental Implant Placement

Tooth Abnormalities | Tooth Injuries

United Kingdom
Imperial College London

Enrolling by invitation

Colonoscopy Check-up in People With Lynch Syndrome

Lynch Syndrome

United Kingdom
Nottingham University Hospitals NHS Trust
University of Washington; Seattle Children's Hospital; The Leeds Teaching Hospitals... and other collaborators

Active, not recruiting

CFTR Modulators and Gastrointestinal Complications (CFTR-MAGIC)

Lung Diseases | Cystic Fibrosis | Digestive System Disease | Pancreatic Disease | Distal Intestinal Obstruction Syndrome | Pancreatic Enzyme Abnormality | Gastrointestinal System Disease

United Kingdom
University Hospital Birmingham NHS Foundation Trust
Pancreatic Cancer UK

Recruiting

The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study) (DETECTION)

Pancreatic Exocrine Insufficiency

United Kingdom
Norgine

Completed

Study to Examine the Effect of Ulimorelin on the Pharmacokinetics of Midazolam in Healthy Volunteers

Digestive System Disorders

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Juvora Dental Solutions

Completed

OHQoL With Removable Partial Dentures; a Pilot Study

Partial Edentulism | Missing Teeth

United Kingdom
Barts & The London NHS Trust

Completed

Lymphocyte Immunophenotyping in Common Variable Immunodeficiency

Bronchiectasis | Common Variable Immunodeficiency | Granulomatous Disease | Immunoglobulin Treatment

United Kingdom
Imperial College London

Recruiting

Multiple Breath Washout, a Clinimetric Dataset

Bronchiectasis | Sleep Disorder | Asthma | Cystic Fibrosis | Bronchitis | Primary Ciliary Dyskinesia

United Kingdom
Enterprise Therapeutics Ltd

Completed

A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD001 in Healthy Subjects

Cystic Fibrosis

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating Safety and Pharmacokinetics of VX-440 in Combination With Tezacaftor/Ivacaftor in Healthy Adult Subjects

Cystic Fibrosis

United Kingdom
Mayo Clinic

Recruiting

Mayo Clinic Upper Digestive Disease Survey (UDD)

Esophageal Cancer | Esophageal Neoplasms | Cancer of the Esophagus | Digestive System Abnormalities | Esophagus Cancer | Cancer of Esophagus | Esophagectomy | Neoplasm, Esophageal | Abnormalities, Digestive System

United States
Spanish Foundation for Neurometrics Development
Fundacion para la Salud Materno Infantil

Enrolling by invitation

Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders (tDCS&ASD)

Social Behavior | Attention | EEG With Periodic Abnormalities | Visual Perceptual Weakness | Fluency Disorder

United Kingdom
University of Hull
University of Dundee

Terminated

Three Dimensional Facial Growth Analysis

Cleft Lip and Palate

United Kingdom
XOMA (US) LLC

Completed

A Single-Dose Open-Label Study of XOMA 358 in Subjects With Congenital Hyperinsulinism

Congenital Hyperinsulinism

United Kingdom, United States
London North West Healthcare NHS Trust

Unknown

Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy

Familial Adenomatous Polyposis

United Kingdom
University of Leicester

Recruiting

Paediatric Brain Injury Following Cardiac Interventions (BICI2Kids)

Congenital Heart Disease

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Molar Incisor Hypomineralisation and Dental Anomalies

Molar Incisor Hypomineralisation

United Kingdom
University of Portsmouth
University Hospital Southampton NHS Foundation Trust

Recruiting

Sweat Response, Sweat Composition and Thermoregulatory Response to Exercise in Heat in Adults With Cystic Fibrosis on Modulator Therapy. (Sweat-CF)

Cystic Fibrosis

United Kingdom
University of Portsmouth
University Hospital Southampton NHS Foundation Trust

Recruiting

Fitness, Body Composition, Physical Activity and Sleep Patterns in People With Cystic Fibrosis on Modulator Therapy. (Understand-CF)

Cystic Fibrosis

United Kingdom
King's College London
Barts & The London NHS Trust; University of Warwick; Coventry University; Cystic...

Completed

Perceptions of the CF Screening Protocol Incorporating NGS

Cystic Fibrosis

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Completed

HFNT During Exercise in CF

Cystic Fibrosis

United Kingdom
Nottingham University Hospitals NHS Trust

Completed

Gut Imaging for Function & Transit in Cystic Fibrosis Study 1 (GIFT-CF1)

Cystic Fibrosis

United Kingdom
Belfast Health and Social Care Trust
Queen's University, Belfast

Completed

Parameters to Assess Response to Intra-Venous Antibiotic Treatment for Pulmonary Exacerbations in Cystic Fibrosis (PRIVATE)

Cystic Fibrosis

United Kingdom
Mologic Ltd
Heart of England NHS Foundation Trust

Completed

Study of Urinary Predictors of Exacerbations by Biomarkers in Cystic Fibrosis (SUPERB-CF)

Cystic Fibrosis

United Kingdom

Clinical Trials on Digestive System Abnormalities in United Kingdom

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