Clinical Trials on Disorder of Speech and Language Development in Czechia

Total 83 results

Masaryk University

Completed

Effect of Noninvasive Brain Stimulation on Hypokinetic Dysarthria in Parkinson's Disease

Parkinson Disease

Czechia
Denali Therapeutics Inc.
Takeda

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

Frontotemporal Dementia

Spain, Turkey, France, Belgium, Netherlands, Portugal, Italy, Colombia, Czechia, Brazil, United Kingdom, Serbia
Rigshospitalet, Denmark
Odense University Hospital; Karolinska University Hospital; Turku University... and other collaborators

Recruiting

Cerebellar Mutism Syndrome Study

Infratentorial Neoplasms | Mutism

Norway, Italy, Netherlands, Denmark, Sweden, Belgium, Finland, Austria, Lithuania, Hungary, United Kingdom, Czechia, Germany
Brno University Hospital

Recruiting

Hybrid Rehabilitation Approach Through Group Exercise and Telerehabilitation in Patients With Multiple Sclerosis

Multiple Sclerosis

Czechia
National Institute of Mental Health, Czech Republic

Completed

Virtual Reality Exposure Therapy for Acrophobia

Anxiety Disorders | Specific Phobia | Fear of Heights | Acrophobia

Czechia
Ipsen

Completed

Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq (OPTIMA)

Renal Insufficiency, Chronic | Pituitary Diseases | Dwarfism | Turner Syndrome

France, Germany, Finland, Spain, Belgium, Czechia, Denmark, Greece, Italy, Romania, Russian Federation, Slovakia, Ukraine, United Kingdom
Ferring Pharmaceuticals

Completed

An Open-Label, Multi-centre, Phase III Study of Local Tolerability of ZOMACTON 10MG

Turner's Syndrome

Czech Republic, France, Netherlands
Value Outcomes Ltd.
Charles University, Czech Republic; Institute of Health Information and Statistics...

Completed

Mapping Health-related Quality of Life in Pregnant Women With Thyroid Disease. (ThyPreQol2020)

Quality of Life | Thyroid Diseases | Pregnancy Related

Czechia
IntraBio Inc

Active, not recruiting

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, Slovakia, Netherlands, Czechia, Switzerland
Palacky University

Completed

Evaluation of Life Quality in Post Stroke Patients

Stroke | Quality of Life

Czechia
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Terminated

Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children Aged From 2 to Less Than 7 Years Old With Autism Spectrum Disorder.

Autism Spectrum Disorder (ASD)

Spain, United States, Hungary, Poland, Australia, United Kingdom, Brazil, Czechia, France, Italy, Portugal, Slovakia
Sergiusz Jozwiak
Medical University of Vienna; Charite University, Berlin, Germany; Institut National... and other collaborators

Unknown

Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex (EPISTOP)

Epilepsy | Tuberous Sclerosis Complex | TSC

Poland, Austria, Belgium, Czech Republic, France, Germany, Italy, Netherlands
Dermatology Specialties Limited Partnership

Completed

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Tuberous Sclerosis | Facial Angiofibroma

United States, Taiwan, Serbia, Spain, Australia, Czechia, Hungary, New Zealand, Slovakia
University Hospital Olomouc
University Hospital Ostrava; Tomas Bata Hospital, Czech Republic; General University... and other collaborators

Recruiting

Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy

Cushing Syndrome | Pheochromocytoma | Adrenocortical Carcinoma | Adrenal Cortex Diseases | Adrenocortical Adenoma | Adrenal Tumor | Adrenalectomy; Status | Adrenal Mass | Adrenal Hyperplasia | Adrenal Disease | Adrenocortical Tumor | Conn Adenoma | Adrenal Gland Metastasis

Czechia
University College, London
University of Liverpool

Terminated

Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy (EDIBLE)

Cortical Dysplasia

United Kingdom, France, Austria, United States, Czechia, Germany, Italy, Switzerland
Elena Gurkova
University Hospital Olomouc

Recruiting

Factors Affecting the Quality of Life After Ischemic Stroke in Young Adults (FRAILTY)

Ischemic Stroke

Czechia
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study

Turner Syndrome | Idiopathic Growth Hormone Deficiency

Spain, France, Canada, United Kingdom, Czech Republic, Argentina, Germany, Italy, Sweden
Novo Nordisk A/S

Completed

Observational Prospective Study on Patients Treated With Norditropin®

Chronic Kidney Disease | Turner Syndrome | Noonan Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age

Israel, Saudi Arabia, Spain, Argentina, Russian Federation, Germany, Netherlands, Italy, Belgium, United Kingdom, Slovenia, Ireland, Sweden, Denmark, Hungary, Finland, Norway, France, Czechia, Lithuania, Luxembourg, Serbia, Switzerland
University Hospital Ostrava

Recruiting

The Effect of Chronic Pain and Its Treatment on Quality of Life and Physical Activity

Chronic Pain

Czechia
Sanofi

Recruiting

A Study to Evaluate the Quality of Life of Male and Female Adult Patients With Severe Refractory Atopic Dermatitis Treated With Dupilumab in Czech Republic

Atopic Dermatitis

Czechia
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Czech Republic
University Hospital Ostrava
University of Ostrava

Recruiting

Improving the Quality of Life of Stroke Patients Using the Armeo Spring Device

Ischemic Stroke

Czechia
Millendo Therapeutics US, Inc.

Terminated

Nevanimibe HCl for the Treatment of Classic CAH

Congenital Adrenal Hyperplasia

Spain, Israel, France, Brazil, Czechia
Saniona

Completed

Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS) (2016-003694-18)

Confirmed Genetic Diagnosis of Prader-Willi Syndrome

Czechia, Hungary
Mgr. Eliška Vrátná
Vladimíra Fejfarová, MD, PhD; prof. Ing. Václav Bunc, CSc

Unknown

Musculoskeletal Changes After Physiotherapeutic Intervention in Podiatric Subjects (BIONEDIAN)

Prevention of Diabetic Foot

Czechia
University Hospital Ostrava

Recruiting

The Effect of Autologous Hematopoietic Stem Cell Transplantation on the Lower Urinary Tract Function Related to QoL in MS Patients

Multiple Sclerosis | Lower Urinary Tract Symptoms

Czechia
University Hospital Ostrava

Recruiting

Cardiovascular Fitness of Patients With Multiple Sclerosis, Effect of Exercise on Fatigue and Depression

Multiple Sclerosis

Czechia
Charles University, Czech Republic

Recruiting

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents

Pneumonia | Cough | Asthma | Asthma in Children | Dyspnea | Recurrent Respiratory Tract Infections | Shortness of Breath | Wheezing | Mucus; Plug | Lower Respiratory Tract and Lung Infections | Chest Tightness

Czechia
Faculty Hospital Kralovske Vinohrady

Completed

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Infections | Multiple Sclerosis | Autoimmune Diseases | Diabetes Mellitus, Type 1 | Rheumatoid Arthritis | Vaccine Reaction | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Down Syndrome | Atopic Dermatitis | Vitiligo | Alopecia Areata | COVID-19 Pandemic | Ankylosing Spondylitis | Lupus Erythematosus and other conditions

Czechia
DePuy International

Terminated

Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

Austria, Czech Republic, Finland, Germany, Norway, Portugal, Switzerland, United Kingdom
University Hospital Ostrava

Completed

Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous Lesions

Carcinoma in Situ | Hoarseness | Recurrent Respiratory Papillomatosis | Chronic Inflammation of Hypopharynx | Macroscopic Laryngeal Lesions | Histological Confirmation of Dysplasia | Invasive Carcinoma of Larynx | Invasive Carcinoma of Hypo Pharynx

Czech Republic
Bispebjerg Hospital
World Health Organization; International Network of Health Promoting Hospitals... and other collaborators

Completed

WHO-HPH Recognition Project on Fast-Track Implementation of Clinical Health Promotion (RP)

Smoking | Obesity | Malnutrition | Excessive Drinking | Lack of Physical Activity

Canada, Croatia, Czechia, Denmark, Estonia, Indonesia, Japan, Malaysia, Slovenia, Taiwan, Thailand
Diamyd Medical AB

Completed

Diamyd Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes

Glucose Metabolism Disorders | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic Disease | Vitamin D | Autoimmune Diabetes | Physiological Effects of Drugs | Juvenile Diabetes | Insulin Dependent Diabetes

Czechia, Netherlands, Spain, Sweden
Brno University Hospital

Completed

Quality of Life After Radiofrequency Ablation of Pancreatic Cancer

Pancreatic Cancer

Czech Republic
Charles University, Czech Republic

Completed

Effects of Chronic Dietary Exposure to Branched Chain Amino Acids

Type 2 Diabetes Mellitus With Features of Insulin Resistance

Czech Republic
Jazz Pharmaceuticals

Completed

A Study of the Efficacy and Safety of JZP-258 in Subjects With Narcolepsy With Cataplexy

Narcolepsy With Cataplexy

Belgium, United States, Spain, Czechia, France, Finland
Fondazione IRCCS Istituto Nazionale dei Tumori,...
The Leeds Teaching Hospitals NHS Trust; University of Leeds; European Organisation... and other collaborators

Not yet recruiting

Validation of the European Oncology Quality of Life Toolkit

Cancer | Palliative Care | Survivorship

Hungary, Italy, France, United Kingdom, Netherlands, Estonia, Serbia, Lithuania, Slovenia, Albania, Austria, Belgium, Bulgaria, Croatia, Cyprus, Czechia, Denmark, Finland, Georgia, Germany, Greece, Ireland, Latvia, Moldova, Republic of, Norwa... and more
Allergan

Completed

Safety and Efficacy Study of OnabotulinumtoxinA for the Treatment of Urinary Incontinence Due to Neurogenic Detrusor Overactivity (NDO) in Non-Catheterizing Patients With Multiple Sclerosis (MS)

Multiple Sclerosis | Urinary Incontinence | Neurogenic Bladder

France, Poland, Portugal, Belgium, Canada, Russian Federation, Czechia, United States
Biogen

Completed

Tolerability and Quality of Life Study in Participants Who Switched to Avonex Pen (SFERA)

Multiple Sclerosis | Relapsing-Remitting Multiple Sclerosis | Clinical Isolated Syndrome (CIS)

Czech Republic, Switzerland
Neurocrine Biosciences

Active, not recruiting

Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst)

Congenital Adrenal Hyperplasia

United States, Spain, Belgium, Austria, Bulgaria, Canada, Czechia, France, Germany, Greece, Israel, Italy, Netherlands, Poland, Portugal, Serbia, Sweden, United Kingdom
Jazz Pharmaceuticals

Recruiting

A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy

Narcolepsy

United States, Belgium, Spain, France, Italy, Czechia
Novartis Pharmaceuticals

Completed

Study of Efficacy, Safety, and Quality of Life of Pazopanib in Patients With Advanced and/or Metastatic Renal Cell Carcinoma After Prior Checkpoint Inhibitor Treatment (IO-PAZ)

Metastatic Renal Cell Carcinoma | Advanced Renal Cell Carcinoma

Spain, Germany, United States, Austria, Czechia, United Kingdom, Argentina, Hungary, France, Canada, Chile
UCB Pharma

Completed

Observational Study to Evaluate Risks of Side Effects, Drug Abuse and Dependence in Patients Who Received Xyrem ® on Prescription

Narcolepsy

Austria, Belgium, Czech Republic, Germany, Ireland, Italy, Spain, Switzerland, United Kingdom
Jazz Pharmaceuticals

Completed

A Multicenter Study of the Efficacy and Safety of JZP-258 in the Treatment of Idiopathic Hypersomnia (IH) With an Open-label Safety Extension

Idiopathic Hypersomnia

France, Spain, United States, Belgium, United Kingdom, Poland, Czechia, Finland
Theranexus

Completed

Safety and Efficacy of THN102 in Patients With Parkinson's Disease and Excessive Daytime Sleepiness

Parkinson Disease

United States, France, Czechia, Germany, Hungary
NHS Lothian

Completed

The Management of Transient Loss of Consciousness and Suspected Syncope in European Emergency Departments (SEED)

Syncope

France, Spain, United Kingdom, Belgium, Norway, Czechia, Denmark, Greece, Albania, Austria, Finland, Hungary, Italy, Malta, Poland, Romania, Serbia, Turkey
medac GmbH
Syneos Health; Celerion; Venn Life Sciences

Completed

Treosulfan-based Versus Busulfan-based Conditioning in Paediatric Patients With Non-malignant Diseases

Bone Marrow Failure Syndromes | Inborn Errors of Metabolism | Primary Immunodeficiencies | Haemoglobinopathies

Poland, Czechia, Germany, Italy
Avadel

Completed

Once-Nightly Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

Narcolepsy | Cataplexy | Excessive Daytime Sleepiness

United States, Germany, Australia, Canada, Czechia, France
Targacept Inc.

Completed

Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)

Alzheimer's Disease

United States, Ukraine, Czech Republic, Romania, Slovakia
Merck KGaA, Darmstadt, Germany

Completed

Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS)

Multiple Sclerosis

Hungary, Belgium, Portugal, Slovakia, France, Finland, Poland, Denmark, Czechia, Spain, United Kingdom, Italy, Austria, Greece, Lithuania, Netherlands, Norway, Sweden

Clinical Trials on Disorder of Speech and Language Development in Czechia

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