Clinical Trials on Drug Dependence in United Kingdom

Total 2450 results

Albert Einstein College of Medicine
National Institute on Drug Abuse (NIDA); The City University of New York; Washington...

Completed

Pilot Test of a Community-based Buprenorphine Treatment Intervention

Opioid Dependence | Injection Drug Use

United States
National Institute on Drug Abuse (NIDA)

Completed

Impact of Delta Opioid Receptor Gene (OPRD1) Variations on Treatment Outcome in African Americans

Drug Abuse/Dependence | Genetic Underpinning of Substance Abuse | Polymorphism-genetic | Opiod-Related Disorders

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Medications Development for Drug Abuse Disorders

Opioid Dependence | Opioid Related Disorders | Opioid Addiction

United States
Queen Mary University of London

Completed

Use of Varenicline for 4-weeks Prior to Quitting

Smoking Cessation | Tobacco Dependence

United Kingdom
Queen Mary University of London

Completed

Tailoring Varenicline to Individual Needs (TVIN Study) (TVIN)

Smoking Cessation | Tobacco Dependence

United Kingdom
Queen Mary University of London

Completed

Combination of Nicotine Replacement Therapy (NRT) and Varenicline to Increase Cessation of Tobacco (CONVICT Study) (CONVICT)

Smoking Cessation | Tobacco Dependence

United Kingdom
Queen Mary University of London
Pfizer

Completed

De-nicotinised Cigarettes Study (Denic)

Smoking Cessation | Tobacco Dependence

United Kingdom
H. Lundbeck A/S

Completed

Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol Challenge

Alcohol Dependence

United Kingdom
Cardiff University
European Commission

Completed

Neurofeedback & Alcohol Dependence

Alcohol Dependence

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

MELD as an Adjunct for SEEG Trajectories (MAST)

Epilepsy | Epilepsy, Focal | Epilepsy, Refractory

United Kingdom
Edward Hospital

Completed

Increasing Patient Knowledge of the Signs of Opioid Overdose and Naloxone in a Suburban Treatment Program

Opioid Use Disorder | Opioid Dependence

United States
Southport and Ormskirk Hospital NHS Trust

Completed

A Controlled Trial of Extended Brief Interventions in Alcohol Dependent Patients (ADPAC)

Alcohol Dependence

United Kingdom
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders (COPE)

Alcohol Dependence | Posttraumatic Stress Disorders | Combat Disorders | Drug Dependence

United States
Imperial College London

Recruiting

Evaluating the Safety of Acute Baclofen in Methadone-maintained Individuals With Opiate Dependence. (FORWARDS-1)

Addiction Opiate

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
University College London Hospitals

Terminated

Intermittent Fasting in Refractory Epilepsy

Epilepsy

United Kingdom
Spanish Foundation for Neurometrics Development

Completed

TDCs to Treat Drug-resistant Epilepsy

Other Forms of Epilepsy, Treatment Resistant

United Kingdom
Seattle Institute for Biomedical and Clinical Research
AstraZeneca; VA Puget Sound Health Care System

Completed

Quetiapine for the Reduction of Cocaine Use (AZC)

Substance Abuse | Cocaine Dependence | Drug Abuse | Cocaine Abuse | Cocaine Addiction

United States
Institute of Child Health

Unknown

The Impact of Reducing Overtreatment on Quality of Life in Children With Refractory Epilepsy

Intractable Epilepsy

United Kingdom
University of Kent
Kent Community Health NHS Foundation Trust; NHS Kent and Medway

Recruiting

DE-eSCALation of Opioids Post-surgical dischargE (DESCALE)

Opioid Dependence

United Kingdom
University of Edinburgh

Completed

Extrapyramidal Side-Effects in Antipsychotic Drug Therapeutics

Drug-induced Extrapyramidal Side Effects

United Kingdom
GlaxoSmithKline

Completed

Rosiglitazone And Plaque Study for Type 2 Diabetes Mellitus

Non-insulin-dependent Diabetes Mellitus

United Kingdom
University College, London
Medical Research Council; Invicro

Completed

Do Adolescents and Adults Differ in Their Acute Response to Cannabis? (CannTeenA)

Cannabis | Cannabis Dependence | Cannabis Use | CBD | Adolescent Development | THC | Marijuana | Cannabis Intoxication

United Kingdom
GlaxoSmithKline

Completed

Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement

Substance Dependence

United Kingdom
Yale University
National Institute on Drug Abuse (NIDA)

Withdrawn

HIV Risk Reduction and Drug Abuse Treatment in Iran

HIV Infections | Opiate Dependence

United States, Iran, Islamic Republic of
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Hutchison Medipharma Limited
Covance

Completed

Fruquintinib CYP3A Inhibitor and Inducer Study

Drug Drug Interaction

United States
Biosplice Therapeutics, Inc.

Completed

Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers

Drug-Drug Interaction

United States
Lexicon Pharmaceuticals

Completed

A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects

Drug-drug Interaction

United States
Indiana University
National Institute of General Medical Sciences (NIGMS)

Recruiting

Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

Drug-Drug Interaction

United States
VistaGen Therapeutics, Inc.
Parexel

Recruiting

AV-101 Alone and in Combination With Probenecid in Healthy Subjects

Drug Drug Interaction

United States
Pyramid Biosciences

Completed

A Study of PBI-200 With Ritonavir or Cobicistat in Healthy Volunteers

Drug-drug Interaction

United States
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Blade Therapeutics

Completed

Dedicated Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

United States
Repros Therapeutics Inc.

Completed

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

Drug-drug Interaction

United States
University of California, San Francisco

Completed

Drug-Drug Interaction Between Rifampin and Fluvastatin

Drug-drug Interaction

United States
Egetis Therapeutics
University of Edinburgh; NHS Lothian

Completed

PP100-01 (Calmangafodipir) for Overdose of Paracetamol (POP)

Paracetamol Overdose

United Kingdom
CytoSorbents, Inc

Terminated

Ticagrelor CytoSorb Hemoadsorption (TISORB)

Bleeding | Emergent Cardiothoracic Surgery | Drug Removal

United Kingdom
Qure Healthcare, LLC
Aegis Sciences Corporation

Completed

DDI Effectiveness and Clinical Awareness (DECART)

Drug-Drug Interactions

United States
University of Southern California

Recruiting

Impact of Rifabutin on the Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor

Drug Drug Interaction

United States
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin

Drug-drug Interaction

United States
Queen Mary University of London
Barts & The London NHS Trust; University of Hertfordshire

Recruiting

Examination of Whether an Exercise Programme Reduces Alcohol Consumption Among Alcohol-Dependent Adults (AOA)

Alcohol Use Disorder | Alcohol Abuse or Dependence

United Kingdom
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib

Drug-drug Interaction

United States
Mayo Clinic

Not yet recruiting

Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: (PREPARE-Mayo)

Side Effect of Drug | Pharmacogenomic Drug Interaction | Drug Metabolism, Poor, CYP2D6-Related | Ineffective Drug Action | Drug Metabolism, Poor, CYP2C19-Related

United States
KBP Biosciences
Covance

Completed

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Healthy | Drug Drug Interaction

United States
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Drug Drug Interaction

United States, Sweden
Theravance Biopharma

Completed

Drug-Drug Interaction (DDI) Study for TD-9855

Drug Drug Interaction (DDI)

United States
HUYABIO International, LLC.

Completed

Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects

Drug-drug Interaction

United States, Australia
Bristol-Myers Squibb

Completed

A Phase 1 Drug-drug Interaction Study in Healthy Volunteers (DDI)

Drug-drug Interaction Study

United States
Oregon Health and Science University
Portland VA Medical Center

Completed

Effects of Genotype on Resting State Connectivity During Methamphetamine Administration (MATAAR)

Methamphetamine-dependence

United States

Clinical Trials on Drug Dependence in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Switzerland

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Rare Diseases

Drug Interventions

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