Clinical Trials on Drug Dependence in United States

Total 2451 results

Biotie Therapies Inc.
National Institute on Drug Abuse (NIDA)

Completed

Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers

Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

A Multi-Modal Investigation of the Smoking Cessation Medication Varenicline: Dopaminergic Modulation of Reward Processing and Cognitive Control

Tobacco Use Disorder | Nicotine Dependence

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Completed

Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence

Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic Polymorphisms

Nicotine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From Nonsmokers

Nicotine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Effect of Baclofen on Marijuana Withdrawal and Relapse

Marijuana Dependence

United States
Massachusetts General Hospital
Janssen, LP

Completed

Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine Dependence

Cocaine Dependence

United States
Temple University
National Cancer Institute (NCI)

Completed

Counseling to Reduce Children's SHS Exposure: A Trial With Maternal Smokers

Nicotine Dependence

United States
National Institute on Drug Abuse (NIDA)
University of Minnesota

Completed

Role of Metabolites in Nicotine Dependence (1) - 1

Tobacco Use Disorder

United States
New York State Psychiatric Institute
Novel Cocaine Pharmacotherapies

Terminated

Effects of Vigabatrin on Cocaine Self-Administration

Cocaine Dependence

United States
University of Pennsylvania

Withdrawn

A Study of Baclofen ER (CURE)

Cocaine Dependence

United States
University of Wisconsin, Madison
National Institute on Drug Abuse (NIDA)

Completed

Trial on the Effectiveness of Mindfulness Training for Smokers (MTS)

Nicotine Dependence

United States
Southern Illinois University Carbondale
National Institute on Drug Abuse (NIDA)

Completed

Nicotine Patch for Marijuana Withdrawal (NMW)

Marijuana Dependence

United States
US Department of Veterans Affairs
Duke University; Virginia Polytechnic Institute and State University

Completed

Improving Substance Abuse Treatment Aftercare Adherence and Outcome

Substance Dependence | Treatment Outcome | Compliance

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

Behavioral Incentives to Increase Exercise in Cocaine Dependent Women

Cocaine Dependence

United States
University of Pennsylvania

Completed

Assessment of High Dose Transdermal Nicotine for Fast Metabolizers of Nicotine (HDP)

Nicotine Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Progesterone Treatment for Cocaine-dependent Women: A Pilot Study (PROG)

Cocaine Dependence

United States
H. Lee Moffitt Cancer Center and Research Institute
Pfizer

Completed

Varenicline Effects on Cue Reactivity and Smoking Reward/Reinforcement

Tobacco Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Effects of Naltrexone on Nicotine Reinforcement

Tobacco Dependence

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA); Food and Drug Administration (FDA)

Completed

The Effect of Marijuana and Prescription Medications in Mood, Performance and Sleep

Marijuana Dependence

United States
Vanderbilt University

Completed

Interactions Between Physical Activity and Cannabis Use in Adults

Cannabis Dependence

United States
Mclean Hospital

Suspended

Smoked Nicotine Induced Changes in Hormone Function, Mood States and Behaviors

Nicotine Dependence

United States
Mclean Hospital

Suspended

Effects of Progesterone on Smoked Nicotine Induced Changes in Hormones and Subjective Ratings of Stimulant Drug Effects

Nicotine Dependence

United States
Mclean Hospital

Suspended

Multiple Cigarette Induced Changes in Hormone Function, Mood States and Behavior

Nicotine Dependence

United States
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); Partners HealthCare, Inc.

Completed

Direct to Smoker Outreach in a Health Care Setting (DTS)

Tobacco Dependence

United States
University of Maryland, College Park
American Cancer Society, Inc.

Completed

Behavioral Intervention for Low Income Depressed Smokers in Drug Treatment (BA-DAS)

Drug Use | Cigarette Smoking

United States
Centers for Disease Control and Prevention
Columbia University; New York City Department of Health and Mental Hygiene

Completed

An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment

Tuberculosis | Adherence, Medication | Drug-resistant Tuberculosis | Adherence, Patient

United States
University of Florida
James and Esther King Biomedical Research Program

No longer available

Treatment of Drug Resistant Epilepsy (Cannabidiol)

Epilepsy

United States
Johns Hopkins University
Wake Forest University Health Sciences; University of Washington; Louisiana State... and other collaborators

Completed

Penicillin Allergy Testing in STD Clinics

Penicillin Allergy

United States
Cipherome, Inc.
Santa Clara Valley Medical Center

Terminated

DOAC ADRs Retrospective Study

Drug-Related Side Effects and Adverse Reactions

United States
University of California, San Francisco

Completed

Gender-Responsive Drug Use Treatment for Juvenile Justice Girls

Drug Use

United States
Arlene Fink Associates
University of Southern California

Unknown

Online Education to Inform the Elderly About Age-related Alcohol Risks

Alcohol Consumption | Drug-Food Interaction

United States
University of Utah
Agency for Healthcare Research and Quality (AHRQ)

Active, not recruiting

Shared Decision for Drug Interactions in Oral Anticoagulation (DDInteract)

Anticoagulants | Drug Interactions

United States
Beth Israel Deaconess Medical Center
AbbVie

Recruiting

BOTOX Effects on Seizure Severity and Susceptibility

Drug-resistant Focal Seizure

United States
Duke University
Boston Medical Center; Centers for Disease Control and Prevention; Children's...

Completed

FLUAD® vs. Fluzone® High-Dose Study

Quality of Life | Pain | Adverse Drug Event | Injection Site Reaction | Side Effect of Drug

United States
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA)

Terminated

Varenicline For Nicotine Vaping Cessation In Non Smoker Vaper Adolescents (Pilot)

Nicotine Dependence | Vaping

United States
University of Maryland, Baltimore

Completed

Biomarkers to Measure Treatment Response for Alcohol Dependence

Alcohol Dependence

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

An ACE Inhibitor (Perindopril) or an Angiotensin Receptor Blocker (Candesartan) as a Treatment for Methamphetamine Dependence

Substance Abuse | Methamphetamine Dependence | Methamphetamine Abuse

United States
Virginia Polytechnic Institute and State University

Completed

Remote Alcohol Monitoring and Episodic Thinking (RMET)

Alcohol Dependence | Alcohol-Related Disorders

United States
University of Wisconsin, Madison

Completed

Oral vs. Injectable Naltrexone for Hospitalized Veterans With Alcohol Dependence

Alcohol Dependence

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Varenicline as a Treatment for Methamphetamine Dependence (Varenicline)

Substance Abuse | Methamphetamine Dependence | Methamphetamine Abuse

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

NAC as a Potential Treatment for Methamphetamine Dependence

Substance Abuse | Methamphetamine Dependence | Methamphetamine Abuse

United States
NYU Langone Health
Alkermes, Inc.

Completed

Extended-release Naltrexone for Alcohol Dependence in Primary Care

Alcohol Dependence

United States
National Institute on Alcohol Abuse and Alcoholism...
Eli Lilly and Company

Completed

Effect of LY686017 on Alcohol Craving

Alcohol Dependence | Alcoholism

United States
Institute of Addiction Medicine

Unknown

Neurocognitive Functioning Following The PROMETA® Treatment Protocol In Subjects With Alcohol Dependence

Alcohol Dependence

United States
Indiana University School of Medicine
Brown University; George Washington University; VA Boston Healthcare System

Completed

Research on Individualized Treatment for Alcoholism (RITA)

Alcohol Dependence

United States
The Scripps Research Institute
National Institute on Drug Abuse (NIDA)

Completed

Gabapentin Treatment of Cannabis Dependence

Cannabis Dependence

United States
Medical University of South Carolina

Completed

Effect of Oxytocin on Craving and Therapy Response

Marijuana Dependence

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Recruiting

Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study

Nicotine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Nicotine's Potential Abuse With Menthol

Nicotine Dependence

United States

Clinical Trials on Drug Dependence in United States

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