- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00057187
Improving Substance Abuse Treatment Aftercare Adherence and Outcome
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Background:
Although substance abuse treatment continuing care participation is strongly related to positive treatment outcomes, participation rates are low and few interventions have been developed that improve continuing care adherence and outcome.
Objectives:
The objectives of the study were: 1) to compare the effectiveness of an aftercare intervention consisting of a participation contract, attendance prompts, and attendance reinforcers (CPR) to a standard treatment (STX) on adherence to therapy; and 2) to assess the effects of this intervention on treatment outcome
Methods:
We recruited 150 veterans from the Salem VAMC�s SARRTP who could participate in aftercare. Our population is similar to those in other VA�s (97% male, 54% Caucasian, 46% minority, 49 years mean age, 44% alcohol dependent only, 56% drug dependent, and 44% with a dual diagnosis). In this randomized clinical trial, treatment adherence and outcome were measured at baseline and 3-, 6- and 12-months after participants entered treatment using interviews, questionnaires, alcohol and drug screens, VA medical records, and therapist ratings. The study design is a repeated measures nested cohort design, with an intervention and a standard care group. The primary outcome, abstinence rate, will be analyzed using a logistic regression model in which the parameters of interest are estimated using Generalized Estimating Equations (GEE).
Status:
Participant recruitment and follow-up interviews were completed in June 2003 and August 2004, respectively. The HSR&D final report was submitted in April 2005. The main results paper and additional papers will be submitted for publication in 2005.
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
Virginia
-
Salem, Virginia, United States, 24153
- Salem VA Medical Center, Salem, VA
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
All graduates of the Salem VA's SARRTP who: live within a 60 minute drive of the Salem VAMC, or 1 of our 5 SARRTP outreach clinics; have transportation and a job schedule that allows them to attend outpatient aftercare therapy.
Exclusion Criteria:
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Other: Arm 1
|
Collaborators and Investigators
Investigators
- Principal Investigator: Steven J Lash, PhD, Salem VA Medical Center, Salem, VA
Publications and helpful links
General Publications
- Lash SJ, Burden JL, Monteleone BR, Lehmann LP. Social reinforcement of substance abuse treatment aftercare participation: Impact on outcome. Addict Behav. 2004 Feb;29(2):337-42. doi: 10.1016/j.addbeh.2003.08.008.
- DeMarce JM, Lash SJ, Stephens RS, Grambow SC, Burden JL. Promoting continuing care adherence among substance abusers with co-occurring psychiatric disorders following residential treatment. Addict Behav. 2008 Sep;33(9):1104-12. doi: 10.1016/j.addbeh.2008.02.008. Epub 2008 Feb 23.
- DeMarce JM, Burden JL, Lash SJ, Stephens RS, Grambow SC. Convergent validity of the Timeline Followback for persons with comorbid psychiatric disorders engaged in residential substance use treatment. Addict Behav. 2007 Aug;32(8):1582-92. doi: 10.1016/j.addbeh.2006.11.015. Epub 2007 Jan 24.
- Lash J, Burden L, Fearer A. Contracting, Prompting and Reinforcing Substance Abuse Treatment Aftercare Adherence. Journal of Drug Addiction, Education and Eradication. 2007 Jul 1; 2(3/4):455-490.
- Lash SJ, Stephens RS, Burden JL, Grambow SC, DeMarce JM, Jones ME, Lozano BE, Jeffreys AS, Fearer SA, Horner RD. Contracting, prompting, and reinforcing substance use disorder continuing care: a randomized clinical trial. Psychol Addict Behav. 2007 Sep;21(3):387-97. doi: 10.1037/0893-164X.21.3.387.
Study record dates
Study Major Dates
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- IIR 99-282
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Substance Dependence
-
Medical University InnsbruckCompletedSubstance Abuse | Nicotine Dependence | Tobacco Dependence | Substance DependenceAustria
-
Merck Sharp & Dohme LLCCompletedOpiate Dependence | Substance Dependence | Drug Dependence
-
University of Southern CaliforniaNational Institute on Drug Abuse (NIDA); University of Toronto; RTI InternationalCompletedSubstance Abuse, Intravenous | HIV | Heroin Dependence | Opioid Dependence | Cocaine Dependence | Amphetamine DependenceUnited States
-
University of CincinnatiNational Institute on Drug Abuse (NIDA); MaryhavenUnknownHeroin Dependence | Opiate Dependence | Substance DependenceUnited States
-
California Pacific Medical Center Research InstituteUnknownSubstance Dependence | Amphetamine DependenceUnited States
-
Central Hospital, Nancy, FranceHospital of Jury-les-Metz, France; Healthcare Center of Accompaniment and Prevention...UnknownAlcoholism | Opiate Dependence | Early Satisfaction With Substance Dependence CareFrance
-
University of WashingtonU.S. Army Medical Research and Development CommandCompletedAlcohol Dependence | Substance Abuse | Alcohol Abuse | Substance DependenceUnited States
-
GlaxoSmithKlineWithdrawnAlcohol Dependence | Substance Dependence
-
Macmillan Research Group UKNMP Medical Research Institute; Warwick Research ServicesCompletedAlcohol Dependence | Substance Use Disorder | Drug Dependence,India
-
Rajmonda Nallbani-KomoniUnknownAnalgesic Drug DependenceKosovo
Clinical Trials on Contracting, Prompting and Reinforcing
-
US Department of Veterans AffairsCompletedAlcoholism | Substance Use Disorders | Substance Abuse | Alcohol Abuse | Substance DependenceUnited States
-
State University of New York at BuffaloNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)CompletedObesity, Adolescent | Adolescent Behavior
-
Cwm Taf University Health Board (NHS)PRIME Centre WalesUnknown
-
Northwestern UniversityParker B. Francis Fellowship ProgramCompleted
-
Hospital do CoracaoD'Or Institute for Research and Education; Sociedade Hospital SamaritanoCompleted
-
University of UtahNational Institute of Nursing Research (NINR)Completed
-
Albert Einstein College of MedicineNational Institute on Drug Abuse (NIDA)CompletedHIV | Opiate DependenceUnited States
-
National Institute on Drug Dependence, ChinaMan Wellness Center, Beijing, ChinaNot yet recruitingSexually Transmitted Diseases | HIV/AIDS | Prevention
-
UConn HealthNational Institute on Alcohol Abuse and Alcoholism (NIAAA)Completed
-
University of PennsylvaniaCompletedCoronary Disease | Cardiac Arrest | Cardiovascular Risk FactorsUnited States