Clinical Trials on Drug Drug Interactions in Canada

Total 170 results

Sunnybrook Health Sciences Centre
University Health Network, Toronto

Completed

Effect of an Automated Paging System on Response to Critical Laboratory Values

Drug Drug Interactions | Critical Laboratory Values | Drug Laboratory Interactions

Canada
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Midazolam or Clarithromycin in Healthy Subjects

Drug Drug Interaction

Canada
Abbott

Completed

A Study to Evaluate the Interaction Between Vicodin® CR and Ethanol in Healthy Male and Female Moderate Alcohol Drinkers

Drug Interactions

Canada
Lawson Health Research Institute

Completed

Coffee Interaction With the Antihypertensive Drug Felodipine

Food-Drug Interactions

Canada
Emalex Biosciences Inc.
Syneos Health; Cambridge Cognition Ltd

Recruiting

Drug Interaction Study

Drug Interaction

Canada
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects

Drug Interaction

Canada
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability and Food Effect of Sodium Valproate Minitablets in Healthy Subjects.

Food-drug Interaction

Canada
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Completed

Drug-drug Interaction Study in Healthy Male Volunteers Following the Administration of Pantoprazole and Rosuvastatin

Drug Interaction Potentiation

Canada
SignalChem Lifesciences Corporation
Syneos Health

Completed

Crossover Study to Evaluate the Effect of Food on the Pharmacokinetics of SLC-391 in Healthy Adult Subjects

Food-drug Interaction

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Drug Interaction Potentiation

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin

Drug Interaction Potentiation

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide

Drug Interaction Potentiation

Canada
Akebia Therapeutics

Completed

Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of Vadadustat

Pharmacokinetics | Drug Interaction Potentiation

Canada
University of Alberta

Enrolling by invitation

MinMed: Do Older Adults do Better With Less Medication

Frailty | Aging | Adverse Drug Interaction

Canada
Ottawa Hospital Research Institute
McGill University; Canadian Institutes of Health Research (CIHR)

Completed

Information Systems-enabled Outreach Program for Adverse Drug Events (ISTOP-ADE)

Adverse Drug Events

Canada
Westview Physician Collaborative

Completed

Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care (CMR)

Adverse Drug Events

Canada
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Using Novel Canadian Resources to Improve Medication Reconciliation at Discharge

Adverse Drug Events | Medication Reconciliation

Canada
University of British Columbia
Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Canadian Institutes of... and other collaborators

Recruiting

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Adverse Drug Reaction (ADR)

Canada
University of British Columbia
Genome British Columbia; Genome Canada; Dynacare Laboratories, Inc.

Recruiting

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Adverse Drug Reaction (ADR)

Canada
Nova Scotia Health Authority

Unknown

In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects

Drug Mechanism

Canada
University of British Columbia
BC Centre on Substance Use

Terminated

The Impact of Alternative Social Assistance Disbursement on Drug-related Harm (TASA)

Drug Use

Canada
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability of Orfiril Long 500 mg Prolonged-Release Minitablets and Ergenyl Chrono 500 mg Prolonged-Release Tablets

Multiple Drug Use

Canada
Centre de recherche du Centre hospitalier universitaire...
Lallemand Health Solutions

Completed

Validation of the In-utero Transmission of Probiotics (PROBIO)

In Utero Drug Exposure

Canada
St. Justine's Hospital
CIUSSS du Nord-de-l'Île-de-Montréal

Recruiting

Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population (MEMAS)

Adverse Drug Event

Canada
The Hospital for Sick Children
St. Justine's Hospital

Completed

Deep Brain Stimulation Post Failed Vagal Nerve Stimulation (DBSpostVNS)

Epilepsy, Drug Resistant

Canada
Nova Scotia Health Authority

Not yet recruiting

Enhancing Epilepsy Management With Precision Deep Brain Stimulation (EPI-BOOST)

Epilepsy, Drug Resistant

Canada
McGill University Health Centre/Research Institute...
Centre for Aging and Brain Health Innovation; MED e-care Healthcare Solutions; OMNI Health Care

Withdrawn

MedSafer E-care: an Automated Deprescribing Solution (E-CARE Study) (E-CARE)

Deprescribing | Polypharmacy | Adverse Drug Event

Canada
INSYS Therapeutics Inc

Completed

A Study of the Abuse Potential of Dronabinol in Recreational Cannabinoid Users

Drug Abuse, Medication

Canada
J.J.Swen
Karolinska Institutet; Medical University of Vienna; Uppsala University; St. Antonius... and other collaborators

Completed

PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions (PREPARE)

Adverse Drug Reaction

Austria, Netherlands, Italy, Greece, Slovenia, Spain, United Kingdom
University of British Columbia

Completed

The Effect of Medication Review in High-risk Emergency Department Patients

Adverse Drug Events | Adverse Drug Reactions | Medication-related Problems

Canada
Lawson Health Research Institute

Completed

CYP2D6 Screening for Adverse Drug Reactions to Codeine in Breast Milk

Cytochrome P450 2D6 Ultra-rapid Metabolism

Canada
CHU de Quebec-Universite Laval

Unknown

Amoxicillin Challenge for Penicillin Allergy Diagnosis (Pen-VIE)

Penicillin Allergy

Canada
Centre for Innovation and Research in Aging, Canada
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Unknown

Spread and Scale of a Polypharmacy App

Deprescribing | Polypharmacy | Adverse Drug Event

Canada
Centre for Addiction and Mental Health

Recruiting

"Extended" (Alternate Day) Antipsychotic Dosing

Drug Therapy | Schizophrenia and Related Disorders | Antipsychotic Agents | Drug Administration Schedule

Canada
University of Calgary
Alberta Health services; Hotchkiss Brain Institute, University of Calgary

Recruiting

Pharmacogenetics of Antidepressant-Induced Disinhibition (PGx-AID)

Obsessive-Compulsive Disorder | Anxiety Disorders | Major Depressive Disorder | Antidepressant Drug Adverse Reaction

Canada
University Health Network, Toronto

Terminated

An Evaluation of the Development of Nevirapine Induced Mutations in HIV Patients Initiating or Discontinuing Combination Antiretroviral Therapy

Drug Resistance

Canada
Partner Therapeutics, Inc.

Completed

Study to Evaluate Pharmacokinetics, Pharmacodynamics, and Safety of Sargramostim Administered Subcutaneously, Intravenously, or by Inhalation

Drug Kinetics | Drug Effects on Physiology

Canada
McGill University Health Centre/Research Institute...
University Health Network, Toronto; University of British Columbia; Canadian... and other collaborators

Completed

Reducing Post-discharge Adverse Drug Events Amongst the Elderly: a Multi-centre Electronic Deprescribing Intervention

Adverse Drug Event

Canada
Idorsia Pharmaceuticals Ltd.

Completed

Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users

Healthy Recreational Drug Users

United States, Canada
Vancouver Infectious Diseases Centre
Gilead Sciences; Regina General Hospital

Unknown

STRIBILD in Non-Nucleoside Resistant Patients (SINNR STUDY) (SINNR)

HIV | Illicit Drug User

Canada
University of Toronto
O-Two Medical Technologies

Unknown

Demand-Driven Method for Gas Delivery in a Dental Setting

Feasibility | Comfort | Nitrous Oxide | Dentistry | Drug Delivery System | Drug Administration, Inhalation

Canada
Population Health Research Institute

Completed

Clopidogrel and Aspirin Interaction Study-2 (Interaction2)

Drug Action Increased

Canada
Lawson Health Research Institute
University of Western Ontario, Canada

Unknown

Is There an Adverse Drug Reaction Between Renin-Angiotensin System Blockade and Inhaled Anesthetics

Hypertension

Canada
University of Calgary
Alberta Health services

Completed

Delivering Contingency Management in Outpatient Addiction Treatment (PRISE)

Contingency Management | Substance Use | Methamphetamine-dependence | Substance Use Disorders | Substance Abuse | Drug Use | Methamphetamine | Drug Abuse | Adults | Methamphetamine Abuse | Humans

Canada
Empower Research Inc

Completed

Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids (EMPOWER)

Depressive Disorder | Depression | PTSD | Anxiety Disorders | Anxiety | Psychological | Psychedelic Experiences | Psychedelic Drug Dependence

Canada
Montreal Heart Institute
Roche Diagnostic Ltd.

Completed

Quality of Life and Efficacy Evaluation of Patient Self-monitoring Their Oral Anticoagulation Therapy (ESCAPE)

Quality of Life | Anticoagulants | Drug Monitoring | Pharmacy | Ambulatory Care

Canada
Sunnybrook Health Sciences Centre
Novartis

Completed

Change in Ocular Flora Resistance From Repeated Topical Antibiotic Use

Increased Drug Resistance | Infection Resistant to Quinolones and Fluoroquinolones

Canada
University of Calgary

Recruiting

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Chronic Pain | Drug Dependence of Morphine Type | Symptom, Withdrawal

Canada
McGill University

Recruiting

Using Micro-filaments to Detect "Fast Ripples" and Improve the Identification of the Epileptogenic Zone (NeuroSeizure)

Epilepsy, Refractory

Canada
University of Calgary

Unknown

Voronistat in Pediatric Patients With Drug Resistant Epilepsy

Refractory Epilepsy

Canada

Clinical Trials on Drug Drug Interactions in Canada

Sponsors and Collaborators

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CROs in Kenya

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