Clinical Trials on Drug Hypersensitivity in Canada

Total 1039 results

CHU de Quebec-Universite Laval

Unknown

Amoxicillin Challenge for Penicillin Allergy Diagnosis (Pen-VIE)

Penicillin Allergy

Canada
Innovaderm Research Inc.

Completed

Effect of RANKL Inhibition on UV-induced Immunosuppression

Hypersensitivity, Delayed | Immunosuppression | Ultraviolet Rays | Immune Tolerance/Drug Effects

Canada
Sunnybrook Health Sciences Centre
University Health Network, Toronto

Completed

Effect of an Automated Paging System on Response to Critical Laboratory Values

Drug Drug Interactions | Critical Laboratory Values | Drug Laboratory Interactions

Canada
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Midazolam or Clarithromycin in Healthy Subjects

Drug Drug Interaction

Canada
Philippe Bégin
The Hospital for Sick Children; Centre de recherche du Centre hospitalier universitaire... and other collaborators

Recruiting

Omalizumab to Accelerate a Symptom-driven Multi-food OIT (BOOM)

Immunotherapy | Physiological Effects of Drugs | Food IgE-mediated Allergy | Omalizumab

Canada
James Chodosh, MD, MPH
Massachusetts Eye and Ear Infirmary; Fonds de recherche en ophtalmologie de...

Withdrawn

Topical Infliximab in Autoimmune Eyes With Keratoprosthesis

Stevens-Johnson Syndrome | Mucous Membrane Pemphigoid | Toxic Epidermal Necrolysis (Lyell) Syndrome

United States, Canada
Ottawa Hospital Research Institute
McGill University; Canadian Institutes of Health Research (CIHR)

Completed

Information Systems-enabled Outreach Program for Adverse Drug Events (ISTOP-ADE)

Adverse Drug Events

Canada
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Using Novel Canadian Resources to Improve Medication Reconciliation at Discharge

Adverse Drug Events | Medication Reconciliation

Canada
Westview Physician Collaborative

Completed

Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care (CMR)

Adverse Drug Events

Canada
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability and Food Effect of Sodium Valproate Minitablets in Healthy Subjects.

Food-drug Interaction

Canada
University of British Columbia
Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Canadian Institutes of... and other collaborators

Recruiting

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Adverse Drug Reaction (ADR)

Canada
Emalex Biosciences Inc.
Syneos Health; Cambridge Cognition Ltd

Recruiting

Drug Interaction Study

Drug Interaction

Canada
Abbott

Completed

A Study to Evaluate the Interaction Between Vicodin® CR and Ethanol in Healthy Male and Female Moderate Alcohol Drinkers

Drug Interactions

Canada
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability of Orfiril Long 500 mg Prolonged-Release Minitablets and Ergenyl Chrono 500 mg Prolonged-Release Tablets

Multiple Drug Use

Canada
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects

Drug Interaction

Canada
SignalChem Lifesciences Corporation
Syneos Health

Completed

Crossover Study to Evaluate the Effect of Food on the Pharmacokinetics of SLC-391 in Healthy Adult Subjects

Food-drug Interaction

Canada
Lawson Health Research Institute

Completed

Coffee Interaction With the Antihypertensive Drug Felodipine

Food-Drug Interactions

Canada
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Completed

Drug-drug Interaction Study in Healthy Male Volunteers Following the Administration of Pantoprazole and Rosuvastatin

Drug Interaction Potentiation

Canada
University of British Columbia
BC Centre on Substance Use

Terminated

The Impact of Alternative Social Assistance Disbursement on Drug-related Harm (TASA)

Drug Use

Canada
University of British Columbia
Genome British Columbia; Genome Canada; Dynacare Laboratories, Inc.

Recruiting

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Adverse Drug Reaction (ADR)

Canada
Nova Scotia Health Authority

Unknown

In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects

Drug Mechanism

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Drug Interaction Potentiation

Canada
Centre de recherche du Centre hospitalier universitaire...
Lallemand Health Solutions

Completed

Validation of the In-utero Transmission of Probiotics (PROBIO)

In Utero Drug Exposure

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin

Drug Interaction Potentiation

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide

Drug Interaction Potentiation

Canada
The Hospital for Sick Children
St. Justine's Hospital

Completed

Deep Brain Stimulation Post Failed Vagal Nerve Stimulation (DBSpostVNS)

Epilepsy, Drug Resistant

Canada
St. Justine's Hospital
CIUSSS du Nord-de-l'Île-de-Montréal

Recruiting

Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population (MEMAS)

Adverse Drug Event

Canada
Circassia Limited
Adiga Life Sciences, Inc.

Completed

ToleroMune Grass Follow on Study

Grass Allergy | Rhinoconjunctivitis

Canada
McGill University Health Centre/Research Institute...
Centre for Aging and Brain Health Innovation; MED e-care Healthcare Solutions; OMNI Health Care

Withdrawn

MedSafer E-care: an Automated Deprescribing Solution (E-CARE Study) (E-CARE)

Deprescribing | Polypharmacy | Adverse Drug Event

Canada
Akebia Therapeutics

Completed

Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of Vadadustat

Pharmacokinetics | Drug Interaction Potentiation

Canada
Nova Scotia Health Authority

Not yet recruiting

Enhancing Epilepsy Management With Precision Deep Brain Stimulation (EPI-BOOST)

Epilepsy, Drug Resistant

Canada
Circassia Limited
Adiga Life Sciences, Inc.

Completed

Ragweed-SPIRE Follow-On Study

Rhinoconjunctivitis | Ragweed Allergy

Canada
Hamilton Health Sciences Corporation
AllerGen NCE Inc.; Food Allergy Initiative

Unknown

Development of an Algorithm to Better Predict Clinical Responsiveness to Peanut

Peanut Hypersensitivity

Canada
INSYS Therapeutics Inc

Completed

A Study of the Abuse Potential of Dronabinol in Recreational Cannabinoid Users

Drug Abuse, Medication

Canada
Hamilton Health Sciences Corporation
McMaster University; AllerGen NCE Inc.

Completed

Peanut Allergy Oral Immunotherapy Desensitization

Peanut Allergy

Canada
McMaster University
AllerGen NCE Inc.

Unknown

Canadian Peanut Thresholds Study

Peanut Allergy

Canada
McGill University Health Centre/Research Institute...
The Hospital for Sick Children

Recruiting

Investigating Modified Protocols of Oral Immunotherapy to Validate Efficacy and Safety (IMPROVES)

Egg Allergy | Peanut Allergy | Milk Allergy, Cow's

Canada
Philippe Bégin

Active, not recruiting

Adjuvant Treatment With Abatacept to Promote Remission During Peanut Oral Immunotherapy (ATARI)

Peanut Allergy

Canada
Innovaderm Research Inc.

Completed

Characterization of the Molecular Mechanisms Involved in Delayed-Type Hypersensitivity Reactions to House Dust Mite, Diphencyprone, Nickel, and Tuberculin Purified Protein Derivative in Healthy Volunteers

Delayed Type Hypersensitivity

Canada
Lawson Health Research Institute

Completed

CYP2D6 Screening for Adverse Drug Reactions to Codeine in Breast Milk

Cytochrome P450 2D6 Ultra-rapid Metabolism

Canada
Hamilton Health Sciences Corporation
Canadian Institutes of Health Research (CIHR); AAAAI Foundation

Recruiting

Thresholds In Food Allergy evaluaTion And predictioN (TITAN)

Food Allergy | Tree Nut Allergy

Canada
Allergy Therapeutics

Completed

Different Doses of Tyrosine Adsorbed Tree Pollen Allergoid With Monophosphoryl Lipid A (MPL) in Patients Sensitized to Tree Pollen

Type I Hypersensitivity

Canada
Allergy Therapeutics

Completed

Assessment of Residual Allergenicity of Ragweed Pollen Allergoid With Monophosphoryl Lipid A (MPL) Using Skin Prick Testing

Type I Hypersensitivity

Canada
McGill University Health Centre/Research Institute...

Active, not recruiting

Milk Desensitization in Children

Cow Milk Allergy

Canada
Gordon Sussman Clinical Research
Mast Cell Pharmaceuticals Inc.

Unknown

Pilot Study to Evaluate the Effect of Ketotifen on the Adverse Events Associated With Peanut Desensitization

Peanut Allergies in Children

Canada
Centre for Addiction and Mental Health

Recruiting

"Extended" (Alternate Day) Antipsychotic Dosing

Drug Therapy | Schizophrenia and Related Disorders | Antipsychotic Agents | Drug Administration Schedule

Canada
University of Calgary
Alberta Health services; Hotchkiss Brain Institute, University of Calgary

Recruiting

Pharmacogenetics of Antidepressant-Induced Disinhibition (PGx-AID)

Obsessive-Compulsive Disorder | Anxiety Disorders | Major Depressive Disorder | Antidepressant Drug Adverse Reaction

Canada
McGill University Health Centre/Research Institute...
Julia Upton, Hospital for Sick Children, University of Toronto

Active, not recruiting

Peanut and Tree Nut Desensitization

Peanut Allergy | Tree Nut Allergy

Canada
Allergy Therapeutics

Completed

Assessment of Residual Allergenicity of Tree (Birch, Hazel, and Alder) Pollen Allergoid Using Skin Prick Testing

Type I Hypersensitivity

Canada
University Health Network, Toronto

Terminated

An Evaluation of the Development of Nevirapine Induced Mutations in HIV Patients Initiating or Discontinuing Combination Antiretroviral Therapy

Drug Resistance

Canada

Clinical Trials on Drug Hypersensitivity in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Spain

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations