Clinical Trials on Drug Interactions in United Kingdom

Total 1170 results

Daiichi Sankyo, Inc.

Completed

Phase 1 Study to Evaluate the Safety and Tolerability of DS-1040b IV Infusion With Clopidogrel in Healthy Subjects

Drug Interaction

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the Effects of Multiple Doses of ASP3652 on a Single Dose of Repaglinide in the Body of Healthy Subjects

Healthy Subjects | Drug-Drug Interaction (DDI)

United Kingdom
Hutchison Medipharma Limited

Completed

Fruquintinib Food Effect and Proton Pump Inhibitor Study

Food-drug Interaction | Drug Interaction

United States
Kadmon Corporation, LLC
Quotient Sciences

Completed

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Autoimmune Diseases | Drug-drug Interaction | Fibrotic Disease

United Kingdom
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Qure Healthcare, LLC
Aegis Sciences Corporation

Completed

DDI Effectiveness and Clinical Awareness (DECART)

Drug-Drug Interactions

United States
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between FosD and Verapamil When Taken Together in Healthy Volunteers

Healthy Volunteers | Drug Drug Interactions

United States
Johns Hopkins University
Washington State University; National Center for Complementary and Integrative...

Completed

Interactions Between Cannabinoids and Cytochrome P450-Metabolized Drugs

Drug-Interactions

United States
Biogen

Completed

A Drug Interaction Study of BIIB074 and an Oral Contraceptive Regimen

Drug Interactions

United States
Lexicon Pharmaceuticals

Completed

Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Healthy Subjects

Drug Interactions

United States
University of North Carolina, Chapel Hill
National Institutes of Health (NIH)

Completed

Human Cytochrome P450 4F Enzymes and Drug Interactions

Healthy Volunteers | Drug Drug Interactions

United States
CTI BioPharma
PPD

Completed

Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

Drug Interactions

United States
Vertex Pharmaceuticals Incorporated

Completed

Phase 1 PK Interaction Study Between VX-509 and Prednisone or Methylprednisolone in Healthy Male Subjects

Drug Interactions

United States
Emalex Biosciences Inc.
Syneos Health; Nuventra

Terminated

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates

Drug-Interactions

United States
Bayer

Completed

Effect of Ketoconazole on the Pharmacokinetics of Refametinib

Drug Interactions

United States
University of Tennessee

Completed

Alcohol Inhibits Drug Metabolism by Carboxylesterases

Drug Interactions

United States
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Blade Therapeutics

Completed

Dedicated Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

United States
Repros Therapeutics Inc.

Completed

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

Drug-drug Interaction

United States
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
University of Southern California

Recruiting

Impact of Rifabutin on the Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor

Drug Drug Interaction

United States
Indiana University
National Institute of General Medical Sciences (NIGMS)

Recruiting

Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

Drug-Drug Interaction

United States
VistaGen Therapeutics, Inc.
Parexel

Recruiting

AV-101 Alone and in Combination With Probenecid in Healthy Subjects

Drug Drug Interaction

United States
Pyramid Biosciences

Completed

A Study of PBI-200 With Ritonavir or Cobicistat in Healthy Volunteers

Drug-drug Interaction

United States
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Drug Drug Interaction

United States, Sweden
Hutchison Medipharma Limited
Covance

Completed

Fruquintinib CYP3A Inhibitor and Inducer Study

Drug Drug Interaction

United States
Biosplice Therapeutics, Inc.

Completed

Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers

Drug-Drug Interaction

United States
Lexicon Pharmaceuticals

Completed

A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects

Drug-drug Interaction

United States
University of California, San Francisco

Completed

Drug-Drug Interaction Between Rifampin and Fluvastatin

Drug-drug Interaction

United States
AstraZeneca

Completed

Study in Healthy Volunteers to Investigate the Effects of Ketoconazole on the Pharmacokinetics of NKTR-118

Healthy Volunteers | Bioavailability | Drug- Drug Interactions

United States
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin

Drug-drug Interaction

United States
University of Washington
Fred Hutchinson Cancer Center; National Institute of General Medical Sciences...

Completed

Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions

Adverse Drug Interactions

United States
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib

Drug-drug Interaction

United States
HUYABIO International, LLC.

Completed

Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects

Drug-drug Interaction

United States, Australia
Theravance Biopharma

Completed

Drug-Drug Interaction (DDI) Study for TD-9855

Drug Drug Interaction (DDI)

United States
University of Utah
Cubist Pharmaceuticals LLC

Completed

Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin

Pharmacokinetics | Drug Interactions

United States
University of Illinois at Chicago

Completed

Hop Botanical Dietary Supplements - Metabolism and Safety in Women

Food-Drug Interactions

United States
Melinta Therapeutics, Inc.

Completed

Study to Evaluate the Effect of Delafloxacin on the Pharmacokinetics of Midazolam in Healthy Subjects

VA Drug Interactions

United States
Bristol-Myers Squibb

Completed

A Phase 1 Drug-drug Interaction Study in Healthy Volunteers (DDI)

Drug-drug Interaction Study

United States
Xspray Pharma AB
Axis Clinicals Limited

Completed

Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions

Pharmacokinetics | Drug Interactions

United States
KBP Biosciences
Covance

Completed

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Healthy | Drug Drug Interaction

United States
Medical University of South Carolina
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

Drug Interactions and Bioavailability of Cranberry

Healthy | Drug Interactions

United States
Biota Scientific Management Pty Ltd

Completed

A Drug-Drug Interaction Study to Evaluate the Effect of Vapendavir on the Pharmacokinetics of Midazolam in Healthy Male and Female Volunteers

Drug-Drug Interaction Healthy Volunteers

United States
AstraZeneca

Completed

Effects of Administration of Fostamatinib on Blood Concentrations of an Oral Contraceptive in Healthy Female Subjects

Scientific Terminology Rheumatoid Arthritis, Healthy Female Volunteers, Pharmacokinetics, Oral Contraceptive, Drug-drug Interaction | Laymen Terminology Level of Oral Contraceptive in Blood, Oral Contraceptive, Rheumatoid Arthritis, Drug -Drug Interaction

United Kingdom
Emalex Biosciences Inc.
Syneos Health; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of UGTs on the PK of Ecopipam and Its Active Metabolite

Drug Interaction

United States
Biogen

Completed

Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074

Drug Interaction

United States
University of Florida
State of Florida Consortium for Medical Marijuana Clinical Outcomes Research

Completed

Cannabidiol and CES1 Interactions in Healthy Subjects

Drug Interaction

United States
University of Florida
Bristol-Myers Squibb; Sanofi

Completed

PPI and Clopidogrel Response

Drug Interaction

United States
Emalex Biosciences Inc.
ICON Early Phase Services; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport

Drug Interaction

United States
Johnson & Johnson Consumer and Personal Products...

Completed

Loperamide Grapefruit Juice Interaction PK Trial

Drug Interaction

United States

Clinical Trials on Drug Interactions in United Kingdom

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