Search clinical trials for: REG1

Total 57 results

NightstaRx Ltd, a Biogen Company

Enrolling by invitation

Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa (SOLSTICE)

Choroideremia | X-Linked Retinitis Pigmentosa

United States, United Kingdom, Netherlands, Germany, France, Brazil, Canada, Denmark, Finland
Pomeranian Medical University Szczecin

Terminated

Influence of Cognitive Function Software Therapy on the Improvement of Manual Skills in Multiple Sclerosis Patients

Multiple Sclerosis

Poland
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety and Dosing Evaluation of REG1 Anticoagulation System

Healthy

United States
University of Alberta
Canadian Institutes of Health Research (CIHR); Imperial College London; University... and other collaborators

Completed

An Open Label Clinical Trial of Retinal Gene Therapy for Choroideremia

Choroideremia

Canada
Biogen

Completed

Efficacy and Safety of BIIB111 for the Treatment of Choroideremia (STAR)

Choroideremia

United States, Finland, France, Denmark, Netherlands, Germany, United Kingdom, Canada
Anthogyr

Active, not recruiting

Tissue Level vs Bone Level Implants for Plural Restorations : a Multicentre Randomised Controlled Trial (IBERICA)

Edentulous | Dental Implants

Spain, Portugal
Biogen

Completed

A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111 (GEMINI)

Choroideremia

United States, Germany, France
Byron Lam

Completed

Choroideremia Gene Therapy Clinical Trial

Choroideremia

United States
STZ eyetrial
University Hospital Tuebingen

Completed

THOR - Tübingen Choroideremia Gene Therapy Trial (THOR)

Choroideremia

Germany
Egyptian Atomic Energy Authority

Completed

Uses of Gamma Irradiated Amniotic Membrane as an Alternative Method in Psoriasis Treatment

Psoriasis

Egypt
Egyptian Atomic Energy Authority
Waleed Nemr,Egyptian Atomic Energy Authority

Completed

Uses of Irradiated Human Amniotic Membrane in the Treatment of Dystrophic Epidermolysis Bullosa Patients

Epidermolysis Bullosa | Chronic Skin Ulcer

Egypt
University of Oxford
University College, London; Moorfields Eye Hospital NHS Foundation Trust

Completed

REP1 Gene Replacement Therapy for Choroideremia (REGENERATE)

Choroideremia

United Kingdom
University of Oxford
University College, London; University of Southampton; Moorfields Eye Hospital... and other collaborators

Completed

Gene Therapy for Blindness Caused by Choroideremia

Choroideremia

United Kingdom
Regeneron Pharmaceuticals

Completed

COVID-19 Study Assessing the Efficacy and Safety of Anti-Spike SARS CoV-2 Monoclonal Antibodies for Prevention of SARS CoV-2 Infection Asymptomatic in Healthy Adults and Adolescents Who Are Household Contacts to an Individual With a Positive SARS-CoV-2 RT-PCR Assay

Healthy Participants

United States, Moldova, Republic of, Romania
Regeneron Pharmaceuticals

Completed

COVID-19 Study Assessing the Virologic Efficacy of REGN10933+REGN10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection

COVID-19

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Allogeneic Immunotherapy of Hematological Malignancies Using Regulatory T-cell Selective Depletion (ILDTreg2)

Hematological Malignancies | Relapse | Regulatory T Cell Depletion
Regeneron Pharmaceuticals

Terminated

COVID-19 Administration of Single-Dose Subcutaneous Anti- Spike(s) SARS-CoV-2 Monoclonal Antibodies Casirivimab and Imdevimab in High-Risk Pediatric Participants Under 12 Years of Age

COVID-19

United States
Regeneron Pharmaceuticals

Completed

Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN10933+REGN10987) in Adult Volunteers as Related to COVID-19

Healthy | Chronic Stable Illness

United States
Regeneron Pharmaceuticals

Terminated

COVID-19 Study of Pharmacokinetics, Safety, Tolerability, and Efficacy of Intravenous Anti-Spike(s) SARS-CoV-2 Monoclonal Antibodies (Casirivimab+Imdevimab) for the Treatment of Pediatric Patients Hospitalized Due to COVID-19

COVID-19

United States
Regeneron Pharmaceuticals

Completed

COVID-19 Study Assessing the Safety and Tolerability of Co-Formulated Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (Casirivimab+Imdevimab) in Adult Volunteers

Healthy | Chronic Stable Illness

United States
Sun Yat-sen University

Recruiting

Toripalimab,Celecoxib and Regorafenib in the Treatment of Refractory Advanced Colorectal Cancer (REGOTORICOX)

Colorectal Cancer | Liver Metastases | MSS

China
Mario Arpinati
European Commission

Recruiting

Multiple Donor Treg DLI for Severe Refractory Chronic GVHD (TREG2015001)

Chronic Graft Versus Host Disease

Italy
Assistance Publique - Hôpitaux de Paris

Recruiting

Allogeneic Immunotherapy for Hematological Malignancies by Selective Depletion of Regulatory T Cells (DLI-Boost)

Hematological Malignancies | Relapse | Regulatory T Cell Depletion

France
Regado Biosciences, Inc.

Completed

Feasibility and Safety Study Comparing REG1 Anticoagulation System With Unfractionated Heparin in Elective PCI (REVERSAL-PCI)

Coronary Artery Disease

United States, Argentina
Regado Biosciences, Inc.

Completed

A Study Assessing the REG1 Anticoagulation System Compared Heparin in Subjects With Acute Coronary Syndrome (RADAR)

Acute Coronary Syndrome (ACS)

United States, Canada, Germany, France
Yale University
Medela AG

Completed

Study of Postoperative Chest Tube Management

Lung Resection

United States
Science and Research Centre Koper
University of Trieste; University of Franche-Comté

Unknown

Fitt's Law MI Experiment

Healthy
Peter MacCallum Cancer Centre, Australia
Sanofi; Regeneron Pharmaceuticals; Monash University; University of Adelaide; University...

Recruiting

Deep sequencIng in Cutaneous Squamous CEll caRciNomas (DISCERN)

Neoplasms | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Non-melanoma Skin Cancer | Cutaneous Squamous Cell Carcinoma

Australia
Hospital Occidente de Kennedy
Universidad El Bosque, Bogotá

Completed

Venous Ulcer Treatment With Foam Versus Conservative Treatment (VUTEF)

Venous Ulcer

Colombia
Regeneron Pharmaceuticals

Completed

Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for Hospitalized Adult Patients With COVID-19

COVID-19

United States, Mexico, Romania, Brazil, Chile, Moldova, Republic of
University of Regensburg

Terminated

The ONE Study M Reg Trial (ONEmreg12)

Renal Failure, End Stage

Germany
National Cancer Institute (NCI)

Not yet recruiting

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

Human Papillomavirus-Related Carcinoma

United States, Austria
Regeneron Pharmaceuticals

Completed

COVID-19 Study to Assess Immunogenicity, Safety, and Tolerability of Moderna mRNA-1273 Vaccine Administered With Casirivimab+Imdevimab in Healthy Adult Volunteers

Healthy | Chronic Stable Illness

United States
Reconnect Labs

Completed

Dose-finding Study for the Combination of DMT and Harmine in Healthy Subjects (DHTP)

Healthy

Switzerland
Regeneron Pharmaceuticals

Terminated

A Study to Evaluate Efficacy and Safety of Casirivimab+Imdevimab (Monoclonal Antibodies) for Prevention of COVID-19 in Immunocompromised Adolescents and Adults

Immunocompromised

United States, Mexico
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Study to Evaluate Camrelizumab Plus Rivoceranib (Apatinib) Versus Camrelizumab as Adjuvant Therapy in Patients With Hepatocellular Carcinoma (HCC) at High Risk of Recurrence After Curative Resection or Ablation

Adjuvant Therapy in Patients With Hepatocellular Carcinoma (HCC) at High Risk of Recurrence After Curative Resection or Ablation

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Genzyme, a Sanofi Company; American Association...

Completed

Plerixafor and Cemiplimab in Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Investigational Therapeutics for the Treatment of People With Ebola Virus Disease

Ebola Virus

United States, Congo, The Democratic Republic of the
Regeneron Pharmaceuticals

Terminated

COVID-19 Study to Evaluate Safety, Tolerability, and Efficacy of REGN14256+Imdevimab for the Treatment of COVID-19 Adult and Adolescent Patients Without Risk Factors for Progression to Severe Disease

SARS-CoV-2

United States
Bioven Sdn. Bhd.

Terminated

Vaccine Therapy in Treating Patients With Non-Small Cell Lung Cancer (NSCLC) Stages IIIB/IV (NSCLC)

Non-small-cell Lung Cancer (NSCLC) Stage IIIb/IV

Malaysia
ARCTEC

Completed

Determining the Complete Protection Time of an Insect Repellent With 30% Citriodiol® Against Three Species of Ticks.

Tick Bites

United Kingdom
Mansoura University Hospital

Completed

Clinical Study to Compare Efficacy and Safety of Casirivimab and Imdevimab Combination, Remdesivir and Favipravir in Hospitalized COVID-19 Patients

COVID-19

Egypt
Regeneron Pharmaceuticals

Terminated

Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19

COVID-19

United States, Mexico, Romania
Regeneron Pharmaceuticals

No longer available

Compassionate Use of REGN-COV2 for the Treatment of COVID-19

COVID-19
Red Cross War Memorial Childrens Hospital

Unknown

Efficacy of Combining Topical Antibiotic/Steroid/Moisturizer Therapy Compared to Active Comparator in Atopic Dermatitis.

Severe Atopic Dermatitis

South Africa
Regeneron Pharmaceuticals

Available

R3470-3471-3479 (REGN-EB3) Expanded Access Protocol (EAP) for Treatment of Ebola Virus Disease

Ebola Virus Disease
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Not yet recruiting

Pilot Study Evaluating the Impact of Delay Between Administration of Inmazeb Administration and Vaccination by Ervebo on Vaccine Immune Response on Healthy Volunteers

Ebola Virus Disease

Guinea
Regado Biosciences, Inc.
Icahn School of Medicine at Mount Sinai; The Cleveland Clinic; Parexel; Duke Clinical... and other collaborators

Terminated

A Study To Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI (Regulate)

Coronary Artery Disease

United States
Oslo University Hospital

Unknown

Expiratory and Plasma Propofol Concentration in Gastrological Surgery Patients

Bariatric Surgery Candidate | Cholecystectomy

Norway
Tehran University of Medical Sciences

Completed

Biphasic Insulin Aspart Versus NPH Plus Regular Human Insulin in Type 2 Diabetic Patients

Diabetes Type 2

Iran, Islamic Republic of

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