Clinical Trials on Drug Overdose

Total 3179 results

Unity Health Toronto
Hoffmann-La Roche

Unknown

Assessment of Cardiotoxicity by Cardiac Magnetic Resonance (CMR) in Breast Cancer Patients Receiving Trastuzumab

Stage I-IV Breast Cancer (Neo-adjuvant, Adjuvant, Locally Advanced and Metastatic)

Canada
Lawson Health Research Institute
Imperial College London; Queen's University; Northern Ontario School of Medicine

Completed

Efficacy Study of Panax Ginseng to Boost Antipsychotics Effects in Schizophrenia

Obesity | Schizophrenia | Schizoaffective Disorder | Insulin Resistance | Tardive Dyskinesia

Canada, United Kingdom
University of California, Los Angeles

Completed

Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy

Pain, Postoperative | Patient Satisfaction | Physiological Effects of Drugs | Analgesics, Opioid | Analgesics, Non-Narcotic | Peripheral Nervous System Agents | Return to Work | Activity, Sexual

United States
Suzhou Kintor Pharmaceutical Inc,

Completed

Combination of GT90001 and Nivolumab in Patients With Metastatic Hepatocellular Carcinoma(HCC)

HCC | Metastatic Hepatocellular Carcinoma | Combinations of Drugs; Dependence

Taiwan
City University of New York, School of Public Health
National Institute on Drug Abuse (NIDA); Weill Medical College of Cornell University and other collaborators

Completed

Accessible HCV Care Intervention for People Who Inject Illicit Drugs (PWID)

Hepatitis C | HCV Coinfection | People Who Inject Drugs | PWID

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Fosaprepitant in Patients Receiving Ifosfamide-based Regimen

Sarcoma | Chemotherapy-induced Nausea and Vomiting | Effects of Chemotherapy | Adverse Effects of Medical Drugs

United States
Università degli Studi dell'Insubria

Unknown

Left Atrial Remodelling in Hypertension: Effects of Ramipril or Irbesartan

Diastolic Function | Left Atrial Volume | Renin Angiotensin System | Hypertensive Heart Disease | Antihypertensive Drugs

Italy
University of Oslo

Completed

Respiratory Tract Infections and Prescription Drugs in Children and in Pregnancy

Respiratory Tract Diagnoses (ICPC-2) | Prescriptions of Antibiotics by General Practitioners | Prescriptions of ATC J01 and R Drugs in Participants

Norway
University of Guadalajara
Hospital Civil de Guadalajara; Institute of Experimental and Clinical Therapeutics

Recruiting

Effect of Combined Antioxidant Therapy on Oxidative Stress Markers and Inflammatory Cytokines in Patients With Tinnitus

Oxidative Stress | Tinnitus, Subjective | Tinnitus, Bilateral | Antioxidant Therapy | Psychiatric Drugs | Inflammatory Cytokines | SSRI

Mexico
Centre for Addiction and Mental Health

Completed

Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence

Smoking Cessation | Tobacco Smoking | Tobacco Use Disorder | Substance Use Disorders | Molecular Mechanisms of Pharmacological Action | Tobacco Dependence | Physiological Effects of Drugs

Canada
Algemeen Ziekenhuis Maria Middelares

Recruiting

Extensive CArdioVAscular Characterization and Follow-up of Patients Receiving Immune Checkpoint Inhibitors (CAVACI)

Cancer | Atherosclerosis | Cardiotoxicity | Diastolic Dysfunction | Immune Checkpoint Inhibitor-Related Myocarditis | Immune-related Adverse Event | Cardiac Abnormalities, Variable

Belgium
University of Chicago
National Institute on Drug Abuse (NIDA); New York University; University of Illinois... and other collaborators

Completed

Ending Transmission of HIV, HCV, and STDs and Overdose in Rural Communities of People Who Inject Drugs (ETHIC) (ETHIC)

Hepatitis C | HIV | Opioid-use Disorder | Injection Drug Use

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Cardiovascular Function in Acute Leukemia

Leukemia, Myeloid, Acute | Cardiotoxicity | Leukemia, Lymphoid, Acute

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy (CLARITY)

Cardiotoxicity | Radiation Toxicity | Lung Cancer Stage III | Lung Cancer Stage II

United States
University of Aarhus
Danish Cancer Society

Completed

Anticancer Treatment of Breast Cancer Related to Cardiotoxicity and Dysfunctional Endothelium (ABCDE)

Cardiovascular Disease | Breast Neoplasms | Metabolic Syndrome | Endothelial Dysfunction

Denmark
Catholic University of the Sacred Heart

Completed

Effect of Two Different Dosages of Ethinyl-estradiol in Association With Drospirenone in Women With Polycystic Ovary Syndrome.

Polycystic Ovary Syndrome | Estro-progestin Drugs

Italy
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth...

Active, not recruiting

Multichannel Vestibular Implant Early Feasibility Study

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity

United States
Children's Cancer Hospital Egypt 57357

Completed

Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia

Cardiotoxicity | Bone Tumor | Acute Myeloid Leukemia in Children

Egypt
RenJi Hospital

Completed

Tofacitinib as a GC Sparing Agent for Polymyalgia Rheumatica

Polymyalgia Rheumatica | Safety Issues | Effect of Drug

China
Joseph Jankovic
Andrew Billnitzer, MD

Completed

Pimavanserin Treatment in TS

Tardive Dyskinesia | Tourette Syndrome

United States
European Organisation for Research and Treatment...
Ipsen

Withdrawn

Lanreotide Combined With Telotristat Ethyl or Placebo for the First-line Treatment in Patients With Advanced Well Differentiated Small Intestinal Neuroendocrine Tumours (siNET) With Highly-functioning Carcinoid Syndrome (TELEFIRST)

Small Intestinal NET | Carcinoid Heart Disease
University of North Carolina, Charlotte
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Herbal Therapy for Subcutaneous Injection Site Reactions in Multiple Sclerosis (MSSkin)

Multiple Sclerosis

United States
Johns Hopkins University
National Institute on Aging (NIA); Labyrinth Devices, LLC

Recruiting

Vestibular Implantation in Older Adults

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Bilateral Vestibulopathy | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity | Bilateral Vestibular Hypofunction | Aminoglycoside Ototoxicity | Presbyvestibulopathy

United States
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth...

Recruiting

Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Bilateral Vestibulopathy | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity | Bilateral Vestibular Hypofunction | Aminoglycoside Ototoxicity

United States
Yonsei University

Recruiting

Impact of IntraVascular UltraSound Guidance on the Outcomes of Xience Prime Stents in Long Lesions (IVUS-XPL Study): Retrospective and Prospective Follow-up Study

Myocardial Ischemia(Implanted Drug-eluting Stents Because of Ischemic Heart Disease(Stable Angina, Acute Coronary Syndrome))

Korea, Republic of
University of Southern Denmark
Region of Southern Denmark

Completed

Central and Peripheral Nervous System Changes as Markers of Disease Progression in Multiple Sclerosis

Multiple Sclerosis | Drug Effect | Genetic Disease | Central Nervous System Lesion | Neurophysiologic Abnormality | Neurodegeneration | Neurologic Deficits | Peripheral Nervous System Problem

Denmark
Daniel Rushing

Completed

Strain Echocardiography to Predict Cardiotoxicity in Patients Receiving Chemotherapy Containing Doxorubicin

Sarcoma | Lymphoma | Breast Neoplasms

United States
Sound Pharmaceuticals, Incorporated
VA Puget Sound Health Care System

Unknown

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

Head and Neck Cancer | Lung Cancer | Hearing Loss | Ototoxicity | Tinnitus | Neuropathy

United States
Assiut University

Unknown

Acute and Chronic Toxicity of Some Synthetic Cannabinoids in Assiut Psychiatric Hospitals

Epidemiologic Data of Some Synthetic Cannibinoids Toxicity in Patients Presenting at Assiut University Hospital, Psychiatric Hospital of Ministry of Health) | Proportion of Acute and Chronic Abusers of Synthetic Cannibinoids Among Cases of Illicit Drugs Abuser in Studied Sites

Egypt
Peking University People's Hospital
Jiangsu HengRui Medicine Co., Ltd.; Peking University Shougang Hospital

Withdrawn

Famitinib Plus Camrelizumab & Famitinib Alone & Famitinib Plus Ifosfamide in Advanced Osteosarcoma

Progression | Pediatric Cancer | Effect of Drugs

China
Butantan Institute

Completed

Active Surveillance for Adverse Events Following Immunization With the Butantan Trivalent Influenza Vaccine (2018) (FLU-06-IB)

RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Influenza, Human | Orthomyxoviridae Infections | Physiological Effects of Drugs | Vaccines

Brazil
Beijing Ditan Hospital

Unknown

The Effect of Anti-viral Drugs Used in Late Pregnancy on Long-term Development of Children

the Safety of Anti-viral Drugs Used in Late Pregnancy
Richmond Pharmacology Limited

Completed

Food and Insulin Effect on QT/QTC Interval of ECG (C11035)

Effects of Different Meals on the QT/QTc Interval | Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use | C-Peptide Effects on the QT/QTc Interval | Moxifloxacin ECG Profile in Fed and Fasted State | Japanese vs. Caucasian TQT Comparison

United Kingdom
Gunay ER

Completed

Enthesitis Assessment Before and After Anti-Tumor Necrosis Factor Treatment in Spondyloarthritis

Spondyloarthritis | Enthesitis | Anti-Tumor Necrosis Factor Drugs
University Hospital, Basel, Switzerland

Completed

Aspirin Responsiveness and Outcome in Coronary Artery Bypass Graft (CABG) Surgery

Myocardial Ischemia | Thrombosis | Coronary Artery Bypass Graft Triple Vessel | Antithrombotic Drugs [Platelet-aggregation Inhibitors] Causing Adverse Effects in Therapeutic Use

Switzerland
Sun Yat-sen University

Recruiting

The Efficacy and Safety of Rifaximin Treatment

Hepatic Encephalopathy | Hepatitis B | HBV | Effect of Drug | Liver Failure, Acute on Chronic | Rifaximin

China
Medical College of Wisconsin
The Cleveland Clinic

Not yet recruiting

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

Ischemia | Coronary Artery Disease | Heart Failure | Hypertension | Diabetes Mellitus | Cardiomyopathies | Peripheral Artery Disease | Cardiotoxicity

United States
Montreal Heart Institute
AstraZeneca

Recruiting

Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia (CarChem)

Lymphoma | Leukemia | Breast Cancer

Canada
RTI International
Durham County Department of Public Health; Guilford County Department of Public... and other collaborators

Terminated

NC Young Women's CoOp

Human Immunodeficiency Virus (HIV) | Condomless Sex | Alcohol and Drug Use | Sexually Transmitted Infection (STI)

United States
University of Nebraska
National Cancer Institute (NCI)

Completed

Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin

Lymphoma | Cardiac Toxicity | Chemotherapeutic Agent Toxicity

United States
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Cape Town

Completed

Effectiveness & Implementation of a Behavioral Intervention for Adherence and Substance Use in HIV Care in South Africa

Alcohol-Related Disorders | Drug Use | Human Immunodeficiency Virus

United States, South Africa
Mirum Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of LUM001 (Maralixibat) With a Drug Withdrawal Period in Participants With Alagille Syndrome (ALGS) (ICONIC)

Alagille Syndrome

France, Belgium, Poland, Australia, Spain, United Kingdom
Second Affiliated Hospital, School of Medicine,...

Unknown

Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR

Myocardial Injury | Osteosarcoma | Cardiotoxicity | Doxorubicin Induced Cardiomyopathy | Chemotherapy Induced Systolic Dysfunction

China
University of Zurich

Unknown

Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases (NEUTROGENE)

Pustular Psoriasis | Erosive Pustular Dermatosis of the Scalp | Behcet's Disease | Dermatitis Herpetiformis | Pyoderma Gangrenosum | Linear IgA Bullous Dermatosis | Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue | Sweet's Syndrome | Bowel-associated Dermatosis-arthritis Syndrome | Acute Generalized Exanthematous Pustulosis and other conditions

Switzerland
Sun Yat-sen University

Not yet recruiting

Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeted Drugs / Locoregional Therapy in the Treatment of Hepatocellular Carcinoma

Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeting Drugs / Locoregional Therapy for Hepatocellular Carcinoma

China
European Organisation for Research and Treatment...

Not yet recruiting

Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Women With Early Breast Cancer; A Pragmatic Randomized Controlled Trial

Musculoskeletal Pain | Drug-Related Side Effects and Adverse Reactions | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Stage III | HER2-negative Breast Cancer | ER+ Breast Cancer
Luye Pharma Group Ltd.

Recruiting

Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Qilu Hospital of Shandong University

Recruiting

Cardiac Toxicity and Prognostic Value of New Echocardiographic Indicators in the Treatment of Primary Multiple Myeloma

Multiple Myeloma

China
University of California, Los Angeles

Recruiting

FAPI PET for Lung Fibrosis (FAPI ILD)

Pulmonary Fibrosis | Pneumoconiosis | Interstitial Lung Disease | Idiopathic Interstitial Pneumonias | Radiation Pneumonitis | Hypersensitivity Pneumonitis | Drug-Induced Pneumonitis

United States
Odense University Hospital

Recruiting

COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA) (COLA)

Radiation Toxicity | Cardiac Disease | Cardiac Toxicity | Lung Cancer Stage III | Lung Cancer Stage II

Denmark

Clinical Trials on Drug Overdose

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mozambique

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Drug Interventions

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