Clinical Trials on Drug Effect

Total 5420 results

British University In Egypt

Completed

Niosomal Propolis as Oromucoadhesive Film: In-vitro, Ex-vivo & In-vivo Investigations

Drug Effect | Drug Effect Prolonged

Egypt
Universidad de Antioquia

Completed

Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia (ECA)

Drug Effect | Tooth Extraction

Colombia
Technical University of Munich

Completed

Detection of Consciousness by EEG and Auditory Evoked Potentials

Anesthesia | Electroencephalography/ Drug Effect

Germany
Izmir Ataturk Training and Research Hospital

Not yet recruiting

The Effects Of Anticholinergic Burden On Daily Living Activities In Elderly Patients

Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Anticholinergic Adverse Reaction | Anticholinergic Syndrome | Antiarrhythmic Drug Adverse Reaction | Antiparkinsonism Drugs Causing Adverse Effects in Therapeutic Use | Antispasmodic Adverse Reaction
Fundación Pública Andaluza para la Investigación...

Not yet recruiting

Proof-of-concept to Evaluate the Efficacy and Safety of Prednisone in Idiosyncratic Hepatotoxicity (DILICORT)

Prednisone | Hepatotoxicity | Idiosyncratic Drug Effect
King Faisal Specialist Hospital & Research Center

Completed

Interaction Between Drug and Placebo Effect:Randomized Placebo Controlled Trials May Not be Accurate in Determining Drug Effect Size

Placebo Effect | Placebo Drug Interaction

Saudi Arabia
Jinnah Postgraduate Medical Centre

Completed

Comparison of Efficacy of Tranexamic Acid Mesotherapy Versus 0.9% Normal Saline for Melasma

Effect of Drugs | Adverse Effects of Medical Drugs

Pakistan
Clinical Hospital Centre Zagreb
Croatian Science Foundation; University of Zagreb School of Medicine

Recruiting

Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Cardiovascular Drugs

Croatia
Diakonhjemmet Hospital
University of Oslo; Diakonhjemmet Hospital Pharmacy; Diakonhjemmet Foundation

Completed

Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial (EPIMERR)

Drug-Related Side Effects and Adverse Reactions | Drug Interaction Potentiation | Medication Compliance | Remission | Medicinal Substance; Adverse Effect

Norway
Yale University

Completed

Neuroimmune Effects of Opioid Administration (NOA)

Drug Effect

United States
King Faisal Specialist Hospital & Research Center

Completed

The Placebo Effect May Involve Modulating Drug Bioavailability

Pharmacokinetics | Placebo Effect | Drug Half Life

Saudi Arabia
Ain Shams University

Recruiting

Effect of Dexmedetomidine on Left Ventricular Function in Coronary Artery Bypass Graft Surgery Outcome (CABAG)

Effect of Drug in CABAG Patients

Egypt
Washington University School of Medicine

Completed

Efavirenz and Ritonavir on Human Brain P-Glycoprotein

Drug Effects

United States
Peking University People's Hospital
Peking University Shougang Hospital

Suspended

Apatinib Plus IE Chemotherapy (Ifosfamide and Etoposide) for Relapsed or Refractory Osteosarcoma (AIEO)

Effect of Drug | Toxicity, Drug

China
Beijing Anzhen Hospital

Unknown

the Effect Between Platelet Reactivation and Antiplatelet Drugs

Drug Effect Disorder | Platelet Procoagulant Activity Deficiency

China
Technical University of Munich

Completed

Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers

Anesthesia | Drug Effects

Germany
National Cancer Institute, Egypt

Recruiting

Comparison of Duloxetine Versus Pregabalin

Drug Effect

Egypt
The Young Investigator Group of Cardiovascular...

Completed

The Effects of Sacubitril/Valsartan on the Heart Functions

Drug Effect
University Hospital, Geneva

Terminated

Evaluation of Pupillometry for cyp2d6 Phenotyping in Children Treated With Tramadol (PUPICYP)

Drug Effect | Drug Intolerance | Cytochrome P450 CYP2D6 Enzyme Deficiency

Switzerland
Beni-Suef University

Unknown

Comparative Effect of Transforaminal Injection of Magnesium Sulphate Versus Ozone Therapy on Oxidative Stress Biomarkers in Lumbar Disc Related Radicular Pain

Effect of Drug

Egypt
Tanta University

Unknown

The Off Label Use of Glycopyrrolate in the Adults Intensive Care Unit.

Effect of Drugs

Saudi Arabia
Suez Canal University

Unknown

Dexmedetomidine Adjuvant to General Anesthesia of Abdominal Hysterectomy

Effect of Drugs
Dow University of Health Sciences

Not yet recruiting

Comparison of the Anti-Inflammatory Efficacy of Preemptive Dexamethasone and Etoricoxib

Effect of Drug
Ain Shams University

Completed

Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment

Effect of Drug

Egypt
Tabula Rasa HealthCare

Enrolling by invitation

Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Frail Elderly Adults With Polypharmacy

COVID | Drug Effect | Adverse Drug Event | Drug Interaction

United States
Beni-Suef University

Unknown

Comparative Effect of Hypotensive Anaesthesia on Event Related Potentials, Quantitative Electroencephalograghy

Effect of Drugs
Peking University People's Hospital
Peking University Shougang Hospital

Completed

Apatinib + Ifosfamide and Etoposide for Relapsed or Refractory Osteosarcoma

Effect of Drug | Toxicity, Drug | Secondary Resistance

China
The Hospital for Sick Children

Withdrawn

Development of a Morphine Pharmacokinetic and Pharmacodynamic Model for the Neonatal Population

Pain | Drug Effect
Lykos Therapeutics

Not yet recruiting

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)

Psychological Effects of Study Drug
Bayer

Completed

Pharmacy Based Pharmacoepidemiological Observational Study With Aspirin Protect 100 mg

Aspirin | Drug Safety | Effects, Longterm

Germany
Tabula Rasa HealthCare
Cambia Health Solutions

Enrolling by invitation

Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Adults With Polypharmacy Using Data From Large Medicare and Commercially Insured Populations

COVID | Drug Effect | Adverse Drug Event | Drug Interaction

United States
Lykos Therapeutics

Completed

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-1)

Psychological Effects of Study Drug

United States
University of Geneva, Switzerland
All India Institute of Medical Sciences, New Delhi; Swiss National Science... and other collaborators

Recruiting

Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia (MPGx-INDALL)

Drug Effect | Pediatric Cancer | Adverse Drug Event | Drug Interaction | ALL, Childhood | Drug Toxicity | Toxicity, Drug | Relapse Leukemia

India
Yuzuncu Yıl University

Completed

Flurbiprofen Tablet vs Spray In Oral Soft Tissue Wounds

Drug Effect | Drug Use | Oral Soft Tissue Conditions

Turkey
Assaf-Harofeh Medical Center

Unknown

ACEIs and ARBs Treatment in Diabetic Patients -Drug Interactions and Adverse Drug Effects

Diabetes Mellitus Type 2

Israel
Osijek University Hospital
Josip Juraj Strossmayer University of Osijek

Completed

An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia

Drug Effect | Anesthesia | Propofol
Getz Pharma

Completed

Research on Human Insulin rDNA Safety and Efficacy in Patients With Type 2 Diabetes Mellitus (RISE)

Type 2 Diabetes Treated With Insulin | Adverse Drug Event | Effect of Drug

Pakistan
Peking University People's Hospital
Chinese Sarcoma Study Group

Recruiting

Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma (MAPAC)

Osteosarcoma | Chemotherapy Effect | Survival | Toxicity, Drug

China
Johns Hopkins University
National Institutes of Health (NIH)

Not yet recruiting

Behavioral Pharmacology of Orally Administered THC and D-limonene

THC | Subjective Drug Effects | D-limonene

United States
Duke University
Boston Medical Center; Centers for Disease Control and Prevention; Children's...

Completed

FLUAD® vs. Fluzone® High-Dose Study

Quality of Life | Pain | Adverse Drug Event | Injection Site Reaction | Side Effect of Drug

United States
Seoul National University Hospital

Recruiting

Dose Finding Study for Remimazolam in Children

Drug Effect

Korea, Republic of
Auburn University

Recruiting

Joint Health Study

Effect of Drug

United States
Paris Translational Research Center for Organ Transplantation

Unknown

Long-term Outcomes After Conversion to Belatacept

Immunosuppression | Kidney Transplant Failure and Rejection | Drug Effect Prolonged | Graft Loss
Faculty of Medicine

Completed

Uterotonic Efficacy of Oxytocin 2.5 Versus 10 Units During Caesarean Section at Mulago Hospital

Uterine Hemorrhage | Adverse Effect of Oxytocic Drugs | Inappropriate Dose of Drug Administered

Uganda
Tabula Rasa HealthCare

Withdrawn

Assessment of Mortality Rates in COVID-19 Infected Populations Treated With Repurposed Medications

COVID | Drug Effect | Risk Reduction | Drug Interaction

United States
David Vivas
St Carlos Hospital, Madrid, Spain

Completed

Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate (ECCLIPSE)

Adverse Effect of Antithrombotic Drugs

Spain
First Affiliated Hospital of Zhejiang University
Beijing Xuze Medical Technology Co., LTD.

Completed

PK-PD Comparative Study of Lansoprazole Capsules and Lansoprazole Enteric-coated Capsules in Healthy Chinese Volunteers

Safety Issues | Effect of Drugs

China
First Affiliated Hospital of Zhejiang University
Jiangsu Aosaikang Pharmaceutical Co., Ltd.

Unknown

A Clinical Trial to Evaluate the Safety and Tolerability of Dexlansoprazole Injection in Healthy Chinese Adults（Part 2）

Safety Issues | Effect of Drugs

China
First Affiliated Hospital of Zhejiang University
Beijing Xuze Medical Technology Co., LTD.

Completed

Pharmacokinetic Study of Lansoprazole Capsules in Healthy Chinese Volunteer

Safety Issues | Effect of Drugs

China
Jianxiang Wang
Xian-Janssen Pharmaceutical Ltd.

Unknown

Therapeutic Effect and Safety Study of Decitabine in Elderly Acute Myeloid Leukemia Patients

Untreated Adult Acute Myeloid Leukemia | Effect of Drugs | Drug Safety

Clinical Trials on Drug Effect

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