Clinical Trials on Drug Interaction Study

Total 3930 results

Syndax Pharmaceuticals

Completed

A Study to Examine the Effects of Entinostat on Midazolam in Healthy Adult Subjects

Healthy Volunteer | Drug Interaction

United States
Hadassah Medical Organization

Completed

Impact of Omeprazole and Fluvoxamine on Platelet Response to Clopidogrel

Drug Interaction of Clopidogrel

Israel
AstraZeneca

Completed

Study in Healthy Volunteers to Investigate the Effects of Ketoconazole on the Pharmacokinetics of NKTR-118

Healthy Volunteers | Bioavailability | Drug- Drug Interactions

United States
Jupiter Orphan Therapeutics Inc.
National Institute on Aging (NIA)

Completed

JOTROL PK, Safety, and Food Effect Assessment

Pharmacokinetics | Food-drug Interaction | Safety

United States
King Faisal Specialist Hospital & Research Center

Completed

Interaction Between Drug and Placebo Effect:Randomized Placebo Controlled Trials May Not be Accurate in Determining Drug Effect Size

Placebo Effect | Placebo Drug Interaction

Saudi Arabia
Emalex Biosciences Inc.
Syneos Health; Nuventra

Terminated

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates

Drug-Interactions

United States
Bayer

Completed

Microgynon Riociguat Drug Interaction Study in Healthy Postmenopausal Women

Drug Interactions

Germany
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
Bayer

Completed

Effect of Ketoconazole on the Pharmacokinetics of Refametinib

Drug Interactions

United States
University of Tennessee

Completed

Alcohol Inhibits Drug Metabolism by Carboxylesterases

Drug Interactions

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
Taipei Veterans General Hospital, Taiwan

Completed

Modeling and Application of Triple Drug Response Surface Models

Pharmacodynamics | Drug Interactions

Taiwan
University of Washington
Fred Hutchinson Cancer Center; National Institute of General Medical Sciences...

Completed

Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions

Adverse Drug Interactions

United States
Lawson Health Research Institute

Completed

Coffee Interaction With the Antihypertensive Drug Felodipine

Food-Drug Interactions

Canada
University of Utah
Cubist Pharmaceuticals LLC

Completed

Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin

Pharmacokinetics | Drug Interactions

United States
University of Illinois at Chicago

Completed

Hop Botanical Dietary Supplements - Metabolism and Safety in Women

Food-Drug Interactions

United States
Melinta Therapeutics, Inc.

Completed

Study to Evaluate the Effect of Delafloxacin on the Pharmacokinetics of Midazolam in Healthy Subjects

VA Drug Interactions

United States
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia

Anesthesia | Drug Interaction | Anesthesia; Functional

Taiwan
Ventrus Biosciences, Inc
TKL Research, Inc.

Completed

Study to Evaluate the Interaction Potential of Clarithromycin XL on Diltiazem Hydrochloride Cream 2% in Healthy Subjects

CLARITHROMYCIN/DILTIAZEM [VA Drug Interaction]

United States
Dr. R. Pfleger Chemische Fabrik GmbH

Completed

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Pharmacokinetics | Drug Interaction Potentiation | Inhibition Enzyme
Cinclus Pharma Holding AB

Completed

Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam

Pharmacokinetics | Safety Issues | Tolerability | Drug Interaction

Sweden
Xspray Pharma AB
Axis Clinicals Limited

Completed

Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions

Pharmacokinetics | Drug Interactions

United States
Medical University of South Carolina
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

Drug Interactions and Bioavailability of Cranberry

Healthy | Drug Interactions

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Healthy Subjects | Pharmacokinetics | DDI (Drug-Drug Interaction)

Germany
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Drug Interaction Study of Folic Acid and Oral Contraceptive Tablets Containing Norgestimate (NGM) /Ethinyl Estradiol (EE) in Healthy Women.

Healthy | Pharmacokinetics | Drug Interactions
Shirley M. Tsunoda

Unknown

Drug Interaction With Envarsus XR and Grapefruit Juice

Kidney Transplant; Complications | Drug Interaction Food
Universitaire Ziekenhuizen KU Leuven

Completed

Phenotypic Drug Probes as Predictors of Drug-drug Interactions With Tacrolimus

Kidney Transplantation | Drug Interactions

Belgium
Johnson & Johnson Pharmaceutical Research & Development...

Withdrawn

A Study to Evaluate the Pharmacokinetic Drug Interaction Between Multiple Doses of JNJ-31001074 and a Single Dose of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Women

Healthy | Pharmacokinetics | Drug Interactions
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Drug Interaction Study of Folic Acid and Oral Contraceptive Tablets Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) in Healthy Women.

Contraception | Pharmacokinetics | Drug Interactions
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Drug Interaction Study of JNJ-31001074 and Ketoconazole in Healthy Volunteers

Healthy | Pharmacokinetics | Drug Interactions
University of Zurich
ETH Zurich, Human Nutrition Laboratory

Completed

The Influence of Different Food Componente on Zinc Absorption in Young Adults Consuming Zinc Fortified Porridges Prepared From Maize, Beans and Sorghum: a Series of Six Similar Randomized, Single-blind Studies

Study Not Related to a Disease. Nutrition Study Without Drug Administration.

Switzerland
Kadmon Corporation, LLC
Quotient Sciences

Completed

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Autoimmune Diseases | Drug-drug Interaction | Fibrotic Disease

United Kingdom
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine Administration

Pharmacokinetics | Food-drug Interaction | Ranitidine Adverse Reaction

United States
Lykos Therapeutics

Completed

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-1)

Psychological Effects of Study Drug

United States
Fogarty International Center of the National Institute...
National Institute of Neurological Disorders and Stroke (NINDS); National Institute... and other collaborators

Completed

Effect of Atazanavir-ritonavir on the Pharmacokinetics and Toxicity of Lumefantrine

Drug Interaction

Nigeria
Klemens Budde
Novartis Pharmaceuticals

Completed

Influence of Pantoprazole on the Bioavailability of MMF and EC-MPS

Immunosuppression | Transplantation | Drug Interaction

Germany
Lykos Therapeutics

Not yet recruiting

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)

Psychological Effects of Study Drug
Thai Red Cross AIDS Research Centre

Recruiting

Assessment of Drug-drug Interactions Between Masculinizing Hormone Therapy and Antiretroviral Agents Concomitantly for Pre-exposure Prophylaxis Among Transgender Men

Drug Interaction

Thailand
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride

Drug-drug Interaction,SHR3680

China
Radboud University Medical Center
Astellas Pharma Inc

Recruiting

Determining the Clinical Relevance of the Interaction Between Enzalutamide and the Opioid Morphine and the DOAC Edoxaban (MIND THE GAP)

Drug-drug Interaction

Netherlands
Thai Red Cross AIDS Research Centre

Active, not recruiting

Assessment of Drug-drug Interactions Between Feminizing Hormone Therapy and Emtricitabine/Tenofovir Alafenamide Concomitantly for Pre-exposure Prophylaxis Among Transgender Women

Drug Interaction

Thailand
Johns Hopkins University
American College of Obstetricians and Gynecologists; The Campbell Foundation

Terminated

Pharmacokinetics and Pharmacodynamics of the Etonogestrel Contraceptive Implant When Co-administered With Efavirenz

Drug Interaction

United States
Central South University

Completed

Drug Interaction Study of Olmesartan in Healthy Chinese Volunteers

Drug Interaction of Olmesartan in Healthy Chinese Volunteers

China
Pfizer

Completed

Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants

Healthy Volunteers | Adult | Drug Interactions | Humans

Belgium
Abbisko Therapeutics Co, Ltd

Completed

ABSK091 Food Effect Study in Healthy Subjects

Health, Subjective | Food-drug Interaction

Taiwan
Maastricht University
European Commission

Completed

Possible Effects of Propylthiouracil, Riociguat and Perphenazine on Circulation of Healthy Volunteers (REPO-STROKE1)

Safety Issues | Drug Drug Interaction

Germany
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
Insel Gruppe AG, University Hospital Bern
University of Bern; Center for Primary Care and Public Health (Unisante), University...

Enrolling by invitation

B-free Multistage Trial (B-free)

HIV | Drug Resistance | Drug Drug Interaction

Switzerland
GlaxoSmithKline

Completed

A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential

Neoplasms | Drug Interactions

United States
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States

Clinical Trials on Drug Interaction Study

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