Clinical Trials on Drug Mechanism

Total 3223 results

CTI BioPharma
Covance

Completed

To Evaluate the Effect of Clarithromycin on the Systemic Exposure of Pacritinib in Healthy Subjects

Drug Interaction Study

United States
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide

Drug Interaction Potentiation

Canada
Centre Hospitalier Universitaire de Besancon

Completed

Prevalence of ESBL-producing Enterobacteriaceae as Carbapenem-resistant Enterobacteriaceae in Nursing Homes. (R'EHPAD)

Drug Resistance, Bacterial

France
Assiut University

Unknown

The Prevalence of Sub Optimal Anti Coagulation

Poor Drug Response
Medical University of South Carolina
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

Drug Interactions and Bioavailability of Cranberry

Healthy | Drug Interactions

United States
Max Zeller Soehne AG

Unknown

Drug Cocktail Interaction Study of St. John's Wort Dry Extract Ze 117

Drug Interaction Study

Germany
Children's Mercy Hospital Kansas City
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Biomarkers of CYP2D6 and CYP3A4 Variability in Pediatrics

Drug Metabolism Phenotype

United States
University Hospital, Basel, Switzerland
University of Basel

Completed

Medication Review Focusing on Anticoagulation Therapy in Swiss Community Pharmacies

Drug Therapy Management

Switzerland
Hoffmann-La Roche

Completed

A Pharmacokinetics, Pharmacodynamics and Safety Study of Warfarin in Combination With Tamiflu (Oseltamivir)

Drug Therapy, Combination

United Kingdom
University of Pennsylvania

Terminated

Computer Stop Order Alert to Prevent Concurrent Prescribing of Trimethoprim/Sulfamethoxazole and Warfarin (warf-tmp/smx)

Prescribers' Drug Orders
Soroka University Medical Center

Completed

N-acetylcysteine Protects From Aminoglycosides Induced Nephrotoxicity

Drug Induced Nephrotoxicity

Israel
Finnish Institute for Health and Welfare
European Commission; Hospital District of Helsinki and Uusimaa

Completed

Oral Fluid Screening Devices

Drug-impaired Driving

Finland
Taipei Medical University WanFang Hospital

Completed

Analysis of Drug-drug Interaction Alert Based on Multicenter Clinical Database

Drug Interaction Alert

Taiwan
Eli Lilly and Company

Completed

A Study of the Abuse Potential of Lasmiditan in Participants Who Are Recreational Drug Users

Prescription Drug Abuse (Not Dependent) | Recreational Drug Use

United States
Huazhong University of Science and Technology

Unknown

The Effect of Desflurane on Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting

General Anesthetic Drug Adverse Reaction | Coronary Artery Bypass Graft Redo

China
Hematology Oncology Associates of Central New York

Not yet recruiting

PFA 100 Evaluation and Reference Interval HOACNY

Effect of Drug
Nanfang Hospital of Southern Medical University

Recruiting

A Multi-center Clinical Study of Drug Antibody and Precision Transfusion in China

Drug-specific Antibodies

China
Selcuk University

Not yet recruiting

Rational Drug Use in Elderly People

Rational Drug Use
University Hospital, Montpellier

Recruiting

Incidence and Risk Factor of Drug Related Problem Detected in Inpatient (DRPINPAT)

Drug Related Problem

France
Texas Tech University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Brain Mechanisms of Reducing Polysubstance Use Following a Novel Body-mind Intervention

Multiple Drug Use

United States
Auburn University
VDF FutureCeuticals Inc.

Completed

Whole Coffee Cherry Study (WCCE)

Effect of Drug

United States
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability and Food Effect of Sodium Valproate Minitablets in Healthy Subjects.

Food-drug Interaction

Canada
Sichuan Provincial People's Hospital

Completed

Effective Dose of Remimazolam Combined With Propofol in Painless Gastroscopy

Effect of Drug

China
Il-Yang Pharm. Co., Ltd.

Completed

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and Ilaprazole

Drug Interaction Potentiation

Korea, Republic of
University of Illinois at Chicago
Oregon State University

Completed

Licorice Botanical Dietary Supplements - Metabolism and Safety in Women

Food-drug Interaction

United States
Taipei Veterans General Hospital, Taiwan

Completed

Modeling and Application of Triple Drug Response Surface Models

Pharmacodynamics | Drug Interactions

Taiwan
Tetraphase Pharmaceuticals, Inc.
Department of Health and Human Services

Completed

Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women (BAL)

Normal Drug Tolerance

United States
University of Illinois at Chicago

Completed

Red Clover Botanical Dietary Supplements - Metabolism and Safety in Women

Food-drug Interaction

United States
Dow University of Health Sciences

Completed

Efficacy of Lidocaine and Xylometazoline Intranasal Spray in Anesthetizing Maxillary Teeth

Effect of Drug

Pakistan
University Hospital Inselspital, Berne
Bayer

Completed

Rivaroxaban Hypericum Trial

Drug Interaction Study

Switzerland
F-star Therapeutics, Inc.
PRA Health Sciences

Completed

A Fixed-Sequence, Drug-Drug Interaction Study Between Multiple Oral Doses of Inarigivir Soproxil and a Single Oral Dose of Midazolam in Healthy Subjects

Drug Interaction Potentiation

Netherlands
Brandeis University
Medical University of South Carolina; University of South Carolina; William Jennings... and other collaborators

Completed

SCOSI-M: Preventing Prescription Drug Problems

Prescription Drug Problems

United States
University of Washington
Fred Hutchinson Cancer Center; National Institute of General Medical Sciences...

Completed

Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions

Adverse Drug Interactions

United States
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Drug Interaction Potentiation

Canada
Lawson Health Research Institute

Completed

Coffee Interaction With the Antihypertensive Drug Felodipine

Food-Drug Interactions

Canada
LEO Pharma

Completed

Open-label, Single Center, Non-randomized, Fixed Sequence Phase 1 Drug-drug Interaction Study With LEO 32731 and Midazolam

Drug Interaction Potentiation

Germany
Il-Yang Pharm. Co., Ltd.
Severance Hospital

Completed

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Clarithromycin, Amoxicillin and Ilaprazole (DDI)

Drug Interaction Potentiation

Korea, Republic of
University of Utah
Cubist Pharmaceuticals LLC

Completed

Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin

Pharmacokinetics | Drug Interactions

United States
Nivalis Therapeutics, Inc.
Davita Clinical Research

Completed

A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects

Drug Interaction Potentiation

United States
SK Chemicals Co., Ltd.

Completed

Pharmacokinetic Interaction Study of Dapoxetine 30mg and Mirodenafil 100mg

Drug Interaction Potentiation
Rockefeller University

Completed

Correlates and Consequences of Increased Immune Activation in Injection Drug Users

Intravenous Drug Usage

United States
Medstar Health Research Institute

Unknown

Prevalence and Level of Thienopyridine Resistance Seen in a Contemporary Percutaneous Coronary Intervention or Coronary Artery Bypass Graft Population (VASP)

Increased Drug Resistance

United States
Technical University of Munich

Completed

Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers

Anesthesia | Drug Effects

Germany
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Losartan and PA21

Drug Interaction Potentiation

United States
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Warfarin and PA21

Drug Interaction Potentiation

United States
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Digoxin and PA21

Drug Interaction Potentiation

United States
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Completed

Drug-drug Interaction Study in Healthy Male Volunteers Following the Administration of Pantoprazole and Rosuvastatin

Drug Interaction Potentiation

Canada
Pfizer

Completed

Single Dose Study Of The Effect Of Cyclosporine On The Pharmacokinetics Of PF-04991532 In Health Volunteers

Healthy | Drug Interaction

Belgium
Zhong Wang
Shanxi Zhendong pharmaceutical Co. LTD.

Completed

Post-marketing Safety Surveillance of Compound Kuh-seng Injection: a Registry Study

Adverse Drug Events | Adverse Drug Reactions | Severe Adverse Events | Safety Surveillance | Severe Adverse Reactions

China
Sichuan Haisco Pharmaceutical Group Co., Ltd

Completed

Efficacy and Safety of Polyene Phosphatidylcholine in Treatment of Patients With Acute Drug-induced Liver Injury

Acute Drug Induced Liver Injury

China

Clinical Trials on Drug Mechanism

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Slovakia

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Rare Diseases

Drug Interventions

Dietary Supplements

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