Clinical Trials on Drug Resistance, Microbial

Total 8419 results

University Hospital, Limoges

Recruiting

Acceptability of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users in Non-conventional Structures (SCANVIR)

Hepatitis C | Hepatitis C Virus Infection, Response to Therapy of | Addiction, Alcohol | Addiction Opiate | Transmission, Intravenous Drug Abuser

France
Medical University of Bialystok
University of Bialystok

Recruiting

Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.

Optic Neuritis | Ischemic Optic Neuropathy | Traumatic Optic Neuropathy | Toxic Optic Neuropathy | Compressive Optic Neuropathy | Hereditary Optic Neuropathies

Poland
National Cancer Institute (NCI)

Completed

HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers

HIV Infections | Lung Cancer | Drug Addiction | AIDS | Tobacco Addiction

United States
University of Colorado, Denver
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure

Lung Injury | Infection | Alcohol Abuse | Drugs of Abuse

United States
Tabula Rasa HealthCare

Active, not recruiting

Type 2 Diabetes With Antiplatelet Drugs

Myocardial Infarction | Heart Failure | Type2 Diabetes | Antiplatelet Drugs

United States
M.D. Anderson Cancer Center

Active, not recruiting

Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Small Cell Neuroendocrine Carcinoma | Metastatic Prostate Adenocarcinoma | Castration-Resistant...

United States
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital

Carbapenem Resistant Klebsiella Pneumoniae

Thailand
Lund University

Recruiting

Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIs (PACUTI)

Bacteremia | Urinary Tract Infections | Antibiotic Resistant Infection

Sweden
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Gene Expression in Patients With Metastatic Prostate Cancer Receiving CYP-17 Inhibition Therapy (PROMOTE)

Metastatic Prostate Carcinoma | Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | Hormone-Resistant Prostate Cancer

United States
University of Michigan Rogel Cancer Center
Memorial Sloan Kettering Cancer Center; University of California, San Francisco

Active, not recruiting

Immunotherapy in Patients With Metastatic Cancers and CDK12 Mutations (IMPACT)

Solid Tumor | Metastatic Cancer | Metastatic Castration Resistant Prostate Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy (CASPAR)

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Dan Blazer III, M.D.

Completed

Talimogene Laherparepvec for the Treatment of Peritoneal Surface Malignancies (TEMPO)

Stage IV Peritoneal Surface Dissemination From Gastrointestinal or Recurrent, Platinum-resistant Ovarian Cancer That Cannot be Completely Resected

United States
Pfizer
EMD Serono; Astellas Pharma Inc; Nektar Therapeutics

Terminated

Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors

Squamous Cell Carcinoma of the Head and Neck (SCCHN) | Metastatic Castration Resistant Prostate Cancer (mCRPC)

Spain, United States, Poland, Belgium
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Unknown

ESK981 and Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Castration Levels of Testosterone | Prostate Carcinoma Metastatic in the Bone

United States
Rambam Health Care Campus

Completed

A Study Evaluating the Role of Oral Antibiotics in an Aim to Eradicate Carrier State of Carbapenem- Resistant Klebsiella Pneumonia (KPC).

Klebsiella Pneumoniae Carbapenemase Resistant Associated Bacteremia or Pneumonia

Israel
Bayer

Completed

A Study of Alpharadin With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer (CRPC)

Bone Metastases | Castration-Resistant Prostate Cancer

United States, France
Grupo Español de Investigación en Cáncer de Ovario

Completed

Clinical Trial Investigating Pazopanib in Patients With Platinum-resistant Advanced Ovarian Cancer

Platinum-resistant Advanced Ovarian Cancer

Spain
Northwell Health

Terminated

Cardiomyopathy in Steroid-resistant Nephrotic Syndrome: Impact of Focal Segmental Glomerulosclerosis

Chronic Kidney Disease | Focal Segmental Glomerulosclerosis | Nephrotic Syndrome | Steroid Resistant Nephrotic Syndrome

United States
University of Edinburgh

Recruiting

Fibrosis in Chronic and Delayed Myocardial Infarction (FCDMI)

Aortic Stenosis | Carcinoid Syndrome | Chemotherapy Induced Systolic Dysfunction

United Kingdom
Ain Shams University
Misr International University

Recruiting

Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Cisplatin Among Egyptian Non-small Cell Lung Cancer Patients

Non Small Cell Lung Cancer | Cardiotoxicity | Nephropathy

Egypt
University Hospital, Geneva

Recruiting

Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma

Ototoxicity | Vestibular Schwannoma

Switzerland
Ciusss de L'Est de l'Île de Montréal

Not yet recruiting

Pilot Study for Cyproheptadine in Hospitalized Patient for COVID-19

COVID-19 Pneumonia | Serotonin Syndrome | Platelet Dysfunction | Viral Pneumonia
University of Chicago

Recruiting

Dyspnea and Cardiotoxicity in Multiple Myeloma Patients Who Receive Carfilzomib

Multiple Myeloma | Cardiotoxicity | Dyspnea | Shortness of Breath

United States
Michele Staton
National Institute on Drug Abuse (NIDA)

Completed

Brief Intervention for Rural Women at High Risk for HIV/HCV (WISH)

Hepatitis C | Drug Abuse | Acquired Immune Deficiency Syndrome Virus

United States
Maastricht University Medical Center
Funding: Stichting Internationaal Parkinson Fonds, The Netherlands

Completed

Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes

Parkinson's Disease | Supranuclear Palsy, Progressive | Multiple System Atrophy | Essential Tremor | Vascular Parkinsonism | Parkinsonian Syndrome | Drug Induced Parkinsonism

Netherlands
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies (PROMETEO)

Obesity | Diabetes | Fatty Liver | Metabolic Syndrome | Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Liver Cancer | NAFLD - Nonalcoholic Fatty Liver Disease | HCC - Hepatocellular Carcinoma

Italy
Temple University
The Comprehensive NeuroAIDS Center (CNAC) at Temple University

Terminated

Liraglutide for HIV-associated Neurocognitive Disorder

HIV Infection | Obesity | Overweight | Metabolic Syndrome | Diabetes Mellitus Type 2

United States
Tianjin Medical University General Hospital

Not yet recruiting

Propranolol on Post Stroke Immune Status and Infection

Cardiovascular Diseases | Stroke | Cerebrovascular Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Ischemic Stroke | Molecular Mechanisms of Pharmacological Action | Physiological Effects of Drugs | Propranolol | Immunologic Factors | Beta Blocker

China
Peking University People's Hospital

Recruiting

The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Blood Coagulation Disorders | Thrombocytopenia | Immune Thrombocytopenia | Physiological Effects of Drugs

China
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Recruiting

Decitabine/Cedazuridine and Enzalutamide for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
Nurix Therapeutics, Inc.

Terminated

A Study of DeTIL-0255 in Adults With Advanced Malignancies

Cervical Cancer | Endometrial Cancer | Platinum-resistant Ovarian Cancer

United States
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Active, not recruiting

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) (endTB-Q)

Bacterial Infections | Gram-Positive Bacterial Infections | Tuberculosis | Tuberculosis, Multidrug-Resistant | Pulmonary Tuberculoses | Mycobacterial Infections

Vietnam, Pakistan, India, Kazakhstan, Lesotho, Peru
Duke University

Completed

INJECT: A Pilot Study of Intra-tumoral Injections in Metastatic Urological Cancers

Metastatic Renal Cell Carcinoma | Metastatic Urothelial Carcinoma | Metastatic Castration-resistant Prostate Cancer (mCRPC)

United States
University of Oxford
The Hospital for Sick Children; Oregon Health and Science University; University... and other collaborators

Unknown

Childhood Acute Illness and Nutrition Network (CHAIN)

Pneumonia | Sepsis | Diarrhea | HIV/AIDS | Malnutrition | Bacteremia | Enteropathy | Antibiotic Resistant Strain | TB

Bangladesh, Uganda, Malawi, Pakistan, Kenya
University of North Carolina, Chapel Hill
University of Colorado, Denver; Baylor College of Medicine; Washington University... and other collaborators

Terminated

Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) (STAR-Too)

Cystic Fibrosis | Methicillin-resistant Staphylococcus Aureus

United States
Sun Yat-sen University
Shenzhen Nanshan Center for Chronic Disease Control

Recruiting

Nanshan Elderly Cohort Study (NECS)

Cardiovascular Diseases | Stroke | Hypertension | Obesity | Cancer | Type 2 Diabetes Mellitus | Death | Metabolic Syndrome | Chronic Kidney Disease | Sarcopenia

China
Chinese University of Hong Kong

Recruiting

Incidence of HANA Conditions in HIV-infected Individuals

Metabolic Syndrome | Vitamin D Deficiency | Renal Impairment | HIV | Osteoporosis | Osteopenia | Liver Fibroses

Hong Kong
University of Virginia
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Go Girls! Fitness Support Group Intervention Effectiveness Study (CBS002)

Polycystic Ovary Syndrome | Type 2 Diabetes Mellitus | Insulin Resistance | Abnormal Weight Gain | Excess Weight | Premature Adrenarche

United States
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
University of Aarhus
Danish Cardiovascular Academy (DCA); Danish Diabetes Academy; Sygesikringen Danmark and other collaborators

Recruiting

Polyamine Treatment in Elderly Patients With Coronary Artery Disease (PolyCAD)

Myocardial Infarction | Cardiovascular Diseases | Quality of Life | Inflammation | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Cognitive Impairment | Metabolic Syndrome | Ischemic Heart Disease | Dietary Habits | Diastolic Dysfunction | Cognition Disorder | Hypertensive Heart Disease

Denmark
Pacific Coast Family Medical Group

Enrolling by invitation

Disease Prevention in Clinical Practice Base on Patient Specific Physiology (STOPDISEASE)

Cancer | Atherosclerosis | Atrial Fibrillation | Insulin Resistance | Dementia | PreDiabetes | Type2 Diabetes | NASH - Nonalcoholic Steatohepatitis | Diastolic Dysfunction | Carotid Plaque
Institut de Recerca Biomèdica de Lleida
Diputació de Lleida; Jaume Arnó Renal Foundation; Unit of Detection and Treatment... and other collaborators

Active, not recruiting

The ILERVAS Project: Assessing the Prevalence of Subclinical Vascular Disease and Hidden Kidney Disease (ILERVAS)

Chronic Kidney Diseases | Atherosclerosis | Metabolic Syndrome | PreDiabetes | Subclinical Disease and/or Syndrome

Spain
Stanford University

Completed

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness

Obesity | Schizophrenia | Metabolic Syndrome | Bipolar Disorder | Weight Gain | Ketogenic Dieting | Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Brain Metabolic Disorder

United States
Manuel Luque Ramírez
Instituto de Salud Carlos III

Completed

Phlebotomy and Polycystic Ovary Syndrome

Hyperandrogenism | Metabolic Cardiovascular Syndrome

Spain
Jeffrey L Zitsman, MD

Completed

LAGB as a Treatment for Morbid Obesity in Adolescents

Obstructive Sleep Apnea Syndrome | Metabolic Syndrome | Insulin Resistance | Morbid Obesity | Nonalcoholic Fatty Liver Disease

United States
John Sievenpiper
Canadian Institutes of Health Research (CIHR); Canada Research Chairs Endowment... and other collaborators

Unknown

Meta-Analyses of the Effect of Vegetable Protein for Animal Protein on Cardiometabolic Risk

Hypertension | Obesity | Cardiovascular Disease | Diabetes | Overweight | Metabolic Syndrome | Dyslipidemia | Kidney Injury | Prediabetes | Gout | Dysglycemia | Kidney Disease | Non-alcoholic Fatty Liver Disease (NAFLD)

Canada
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsules Versus Paclitaxel as Weekly Treatment of Relapsed Platinum-resistant Ovarian Cancer

Recurrent Platinum-resistant Ovarian Cancer

China
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma

United States
Orion Corporation, Orion Pharma

Completed

Safety and Pharmacokinetics of ODM-209 (STESIDES)

Advanced Breast Cancer | Metastatic Breast Cancer | Castration-resistant Prostate Cancer | Prostate Cancer Metastatic

Finland, France, Denmark
AbbVie

Completed

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

Bacterial Infections | Staphylococcal Skin Infections | Methicillin-Resistant Staphylococcus Aureus

United States, Bulgaria, Chile, Colombia, Georgia, Greece, Guatemala, Latvia, Mexico, Panama, Spain, Ukraine

Clinical Trials on Drug Resistance, Microbial

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mozambique

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations