Clinical Trials on Drug-Drug Interaction

Total 3268 results

University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity (FLUOXETINE)

Healthy Volunteers | Drug-Drug Interaction
Qure Healthcare, LLC
Aegis Sciences Corporation

Completed

DDI Effectiveness and Clinical Awareness (DECART)

Drug-Drug Interactions

United States
Guangdong Raynovent Biotech Co., Ltd

Completed

A Drug Interaction Study Assess the Effects of ZSP1273 Tablets on the Pharmacokinetics of Warfarin and Midazolam

Warfarin | Drug Drug Interaction | Midazolam

China
University of Southern Denmark

Completed

The Effect of Dicloxacillin on Oral Absorption of Drugs

Healthy Volunteers | Drug-drug Interaction

Denmark
Biota Scientific Management Pty Ltd

Completed

A Drug-Drug Interaction Study to Evaluate the Effect of Vapendavir on the Pharmacokinetics of Midazolam in Healthy Male and Female Volunteers

Drug-Drug Interaction Healthy Volunteers

United States
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Drug-Drug Interaction of Pyrotinib With a Moderate CYP3A Inducer

Healthy Subjects, Drug-drug Interaction, Pyrotinib

China
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction

France
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the Effects of Multiple Doses of ASP3652 on a Single Dose of Repaglinide in the Body of Healthy Subjects

Healthy Subjects | Drug-Drug Interaction (DDI)

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Verapamil Has an Effect on the Uptake and Elimination of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Drug-Drug Interaction (DDI)

France
Muğla Sıtkı Koçman University

Unknown

Epidemiology of Polipharmacy and Potential Drug-Drug Interactions in Elderly Cardiac Outpatients (EPIC)

Polypharmacy | Drug-drug Interactions

Turkey
Boryung Pharmaceutical Co., Ltd

Completed

Drug Interaction Study of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects

Drug-Drug Interaction

Korea, Republic of
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between FosD and Verapamil When Taken Together in Healthy Volunteers

Healthy Volunteers | Drug Drug Interactions

United States
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of Quizartinib on the Pharmacokinetics of the P-gp Substrate Dabigatran Etexilate in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Vicore Pharma AB

Completed

A Trial to Evaluate the Impact of C21 on the Exposure of 4 Substrates in Healthy Volunteers

Drug Interaction

Sweden
Emalex Biosciences Inc.
Syneos Health; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of UGTs on the PK of Ecopipam and Its Active Metabolite

Drug Interaction

United States
Hua Medicine Limited

Completed

DDI Study Between Dorzagliatin and Rifampicin

Drug Interaction

China
Daiichi Sankyo, Inc.

Completed

Phase 1 Study to Evaluate the Safety and Tolerability of DS-1040b IV Infusion With Clopidogrel in Healthy Subjects

Drug Interaction

United Kingdom
Biogen

Completed

Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074

Drug Interaction

United States
Jules Desmeules

Completed

Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail

Drug Interaction

Switzerland
AstraZeneca

Completed

A Drug-Drug Interaction Study Between AZD1981 and Pravastatin to Study the Effect of AZD1981 on the Kinetics of Pravastatin

Drug Interaction

Sweden
University of North Carolina, Chapel Hill
National Institutes of Health (NIH)

Completed

Human Cytochrome P450 4F Enzymes and Drug Interactions

Healthy Volunteers | Drug Drug Interactions

United States
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Emalex Biosciences Inc.
Syneos Health; Cambridge Cognition Ltd

Recruiting

Drug Interaction Study

Drug Interaction

Canada
Nanjing Zenshine Pharmaceuticals

Recruiting

A Study to Evaluate Drug-drug Interaction of ZX-7101A Tablets and Oseltamivir Phosphate Capsules in Healthy Adult Subjects (ZX-7101A-208)

Drug Interaction

China
University Hospital, Bordeaux
Synapse bv

Not yet recruiting

Drug Interactions in Hospital Information System. The PRoSIT System.. (PROSIT)

Drug Interaction

France
University of Florida
State of Florida Consortium for Medical Marijuana Clinical Outcomes Research

Completed

Cannabidiol and CES1 Interactions in Healthy Subjects

Drug Interaction

United States
Shanghai Public Health Clinical Center

Completed

The Drug Interaction Between Albuvirtide (ABT) and Rifampin（RIF） in Healthy Adult Subjects

Drug Interaction

China
Calithera Biosciences, Inc
Novotech (Australia) Pty Limited

Completed

Impact of a Histamine H2 Receptor Antagonist (H2RA) on the Pharmacokinetics (PK) of Telaglenastat in Healthy Subjects

Drug Interaction

Australia
Royal Marsden NHS Foundation Trust
University of Brighton; Pharmacy Research UK

Unknown

The Effect of ENZAlutamide on the Anti-Xa Levels of Patients Receiving DOACs (ENZA-D)

Drug Interaction
University Hospital, Bordeaux

Recruiting

Impact of an Artificial Intelligence Platform on Inappropriate Medication Use in Older Adults (PING)

Drug-drug Interactions | Geriatric Disease

France
Obafemi Awolowo University
University of Liverpool

Completed

Pharmacokinetic Interaction Between Nitazoxanide and Atazanavir/Ritonavir in Healthy Volunteers

Drug Interaction

Nigeria
Emalex Biosciences Inc.
ICON Early Phase Services; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport

Drug Interaction

United States
Seoul National University Hospital

Completed

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects

Drug Interaction

Korea, Republic of
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects

Drug Interaction

Canada
Chinese University of Hong Kong

Completed

The Interaction of Herbs and Statins

Drug Interaction

Hong Kong
Zagazig University

Completed

Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals.

Drug Interaction

Egypt
University of Florida
Bristol-Myers Squibb; Sanofi

Completed

PPI and Clopidogrel Response

Drug Interaction

United States
Johnson & Johnson Consumer and Personal Products...

Completed

Loperamide Grapefruit Juice Interaction PK Trial

Drug Interaction

United States
AstraZeneca

Completed

Study in Healthy Volunteers to Investigate the Effects of Ketoconazole on the Pharmacokinetics of NKTR-118

Healthy Volunteers | Bioavailability | Drug- Drug Interactions

United States
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability and Food Effect of Sodium Valproate Minitablets in Healthy Subjects.

Food-drug Interaction

Canada
Il-Yang Pharm. Co., Ltd.

Completed

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and Ilaprazole

Drug Interaction Potentiation

Korea, Republic of
University of Illinois at Chicago
Oregon State University

Completed

Licorice Botanical Dietary Supplements - Metabolism and Safety in Women

Food-drug Interaction

United States
University of Illinois at Chicago

Completed

Red Clover Botanical Dietary Supplements - Metabolism and Safety in Women

Food-drug Interaction

United States
University Hospital Inselspital, Berne
Bayer

Completed

Rivaroxaban Hypericum Trial

Drug Interaction Study

Switzerland
F-star Therapeutics, Inc.
PRA Health Sciences

Completed

A Fixed-Sequence, Drug-Drug Interaction Study Between Multiple Oral Doses of Inarigivir Soproxil and a Single Oral Dose of Midazolam in Healthy Subjects

Drug Interaction Potentiation

Netherlands
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Drug Interaction Potentiation

Canada

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