Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals.

Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals

Drug drug interactions is frequent in critically ill patients due to polypharmacy, different drug groups and prolonged ICU or hospital stay

Study Overview

• Status: Completed
• Conditions: Drug Interaction
• Intervention / Treatment: Diagnostic test: Survey for drug drug interactions on medscape and lexicomp applications

Detailed Description

This cross sectional study was conducted in Surgical ICU, zagazig University Hospital for 6months period.

Demographic data (age, gender),clinical history data (main diagnosis, ICU stay in days, transfer from emergency room or other departments, on mechanical ventilation or not, state of consciousness

• Study Type: Observational
• Enrollment (Actual): 120

Contacts and Locations

Study Locations

• Egypt
  • Sharquia
    • Zagazig, Sharquia, Egypt, 33735
      • Liza Elsayed Ali

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

All patients admitted to Surgical ICUs, zagazig University Hospital

Description

Inclusion Criteria:

• all patients admitted to Surgical ICUs for six months period

Exclusion Criteria:

• less than one day admission to ICU,not completed data

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Retrospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Severity of Drug interactions by Lexicomp interactions application	Lexicomp interactions classified As: A(no known interactions) B(no action needed) C(monitor therapy) D(consider therapy modification) X (avoid combination)	6months period
Severity of Drug interactions by Medescape interactions checker:	Interactions classified with Medescape interactions checker as :(contraindicated, serious use alternative, monitor closely,minor)	6months period

Collaborators and Investigators

• Sponsor: Zagazig University
• Investigators: Principal Investigator: Liza Shallouf, Zagazig University; Study Director: Heba Matar, Zagazig University

Study record dates

Study Major Dates

• Study Start (Actual): June 15, 2018
• Primary Completion (Actual): January 15, 2019
• Study Completion (Actual): April 20, 2019

Study Registration Dates

• First Submitted: August 25, 2019
• First Submitted That Met QC Criteria: September 1, 2019
• First Posted (Actual): September 6, 2019

Study Record Updates

• Last Update Posted (Actual): September 6, 2019
• Last Update Submitted That Met QC Criteria: September 1, 2019
• Last Verified: August 1, 2019

More Information

Terms related to this study

• Other Study ID Numbers: 4606/28-5-2018

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: Yes
• IPD Plan Description: All data could be shared
• IPD Sharing Time Frame: For indefinite time
• IPD Sharing Access Criteria: Easy, direct information are available for other researchers
• IPD Sharing Supporting Information Type: Study Protocol

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No