Clinical Trials on Drug-Resistant Epilepsy

Total 9873 results

University of Cape Town
University of Stellenbosch; University of Cape Town Lung Institute; University... and other collaborators

Completed

An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosis (NEXT)

Tuberculosis | Multidrug Resistant Tuberculosis | Extensively-drug Resistant Tuberculosis

South Africa
University Hospital, Strasbourg, France

Unknown

Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia (SPREAD)

Focal Epilepsy | Refractory Epilepsy | Focal Cortical Dysplasia

France
Michael A. Gelfand, MD, PhD
Epilepsy Foundation

Completed

Novel Helmet Design in Patients With Seizures

Generalized Tonic Clonic Seizure | Drug Resistant Epilepsy | Drop Seizures | Complex Partial Seizure | Fall Due to Seizure

United States
University Medical Center Groningen

Completed

Drug Interaction Study Between Linezolid and Clarithromycin in Tuberculosis Patients

Multidrug-resistant Tuberculosis | Extensively Drug-resistant Tuberculosis

Netherlands
Centers for Disease Control and Prevention
Yale University; Columbia University; University of KwaZulu

Completed

TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB (LiMiT)

Multi-drug Resistant Tuberculosis | Extensively Drug Resistant Tuberculosis

South Africa
Wits Health Consortium (Pty) Ltd
University of Cape Town; Perinatal HIV Research Unit of the University of the... and other collaborators

Active, not recruiting

Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care

Tuberculosis | Multi Drug Resistant Tuberculosis | Rifampicin Resistant Tuberculosis | Extensively Drug-Resistant Tuberculosis | Pre-XDR-TB

South Africa
Fondation Lenval

Completed

Pharmacogenetics Anomaly Research in Children and Adolescents With Pharmacological Resistance to Psychotropic Drugs (M4P)

Psychotropic Drugs | Drug Resistance

France
Centre Hospitalier Régional Metz-Thionville

Completed

Standard Precautions Versus Contact Additional Precautions Against Multi-drug Resistant Bacteria in Intensive Care Unit (PSBMR) (PSBMR)

Multi-drug Resistant Bacteria

France
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Creatine Deficiency Syndromes (BioCDS) (BioCDS)

Intellectual Disability | Developmental Delay | Intractable Epilepsy | Movement Disorder | Behavioral Disorder

India, Sri Lanka, Egypt
Johns Hopkins University
Vitaflo International, Ltd

Completed

Medium Chain Triglycerides as an Adjunct to the Modified Atkins Diet for Women With Catamenial Epilepsy

Epilepsy | Seizure | Catamenial Epilepsy | Medically Resistant Epilepsy | Medically Resistant Seizures

United States
Emory University
Centers for Disease Control and Prevention

Not yet recruiting

Response to Emerging Antimicrobial Resistance With Containment Microbiota Therapy (REACT)

Multi-Drug Resistant Organism Colonization

United States
Johns Hopkins University
Nutricia Liverpool

Completed

Modified Atkins Diet Plus KetoCal for Adult Epilepsy

Epilepsy | Seizure | Medically Resistant Epilepsy | Medically Resistant Seizures

United States
Danone Nutricia SpA Società Benefit

Recruiting

Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients

Autism Spectrum Disorder | Drug Resistant Epilepsy | Chronic Migraine | Brain Tumor, Pediatric

Italy
Senda Biosciences
Boston Children's Hospital

Withdrawn

Comparison of Microbiome Composition and Biomarkers in Pharmaco Resistant and Pharmaco-Sensitive Epilepsy

Epilepsy in Children | Pharmaco-Resistant Epilepsy

United States
Emory University
Centers for Disease Control and Prevention

Recruiting

Further MT for AntIbiotic-Resistant Bacterial Colonization in Inpatients (FAIR)

Multi-drug Resistant Organism

United States
Emory University
Centers for Disease Control and Prevention

Completed

Sentinel Cohort REACT

Multi-Drug Resistant Organism

United States
Association Pour le Recherche en Infectiologie...
Pr Bruno Fantin

Completed

Epidemiology of Fluoroquinolone Resistance in Human Commensal Flora in Patients Hospitalised in Medical Wards

Colonization | Hospitalized Patients | Multi Drug Resistant Bacteria

France
Human Biome Institute S.A.

Recruiting

Fecal Microbiota Transplantation (FMT) to Decolonize Antibiotic - Resistant Bacteria (ARB) - New Protocol (STOP-ARB2)

Antimicrobial Drug Resistance | Drug Resistance, Bacterial

Poland
Centers for Disease Control and Prevention
Kenya Medical Research Institute

Completed

Brief Bactericidal Activity of Anti-Tuberculosis Drugs (BBA)

Tuberculosis | Drug-resistant Tuberculosis | Isoniazid Resistant Tuberculosis (Disorder)

India
National Institute of Allergy and Infectious Diseases...

Completed

Dose Escalation Study of SQ109 in Healthy Adult Volunteers

TB Multi-drug Resistant

United States
University of Aarhus
Danish Research Agency

Completed

Danish Aspirin Resistance Trial - Pilot Study

Drug Resistance

Denmark
Foundation for Innovative New Diagnostics, Switzerland

Completed

Evaluation of Centralised TB Assay Solutions

Tuberculosis | Drug-resistant Tuberculosis

Georgia, Germany, India, Moldova, Republic of, South Africa
University of Cape Town
Institute of Tropical Medicine, Belgium; Epicentre; Medecins Sans Frontieres,... and other collaborators

Recruiting

Pharmacometrics to Advance Novel Regimens for Drug-resistant Tuberculosis-PandrTB Tuberculosis (PandrTB)

Multi-drug Resistant Tuberculosis

Vietnam, Kazakhstan, Lesotho, Pakistan, Peru, South Africa
University Hospital, Basel, Switzerland

Completed

Aspirin and Clopidogrel Resistance Study

Drug Resistance

Switzerland
Beijing Tiantan Hospital

Active, not recruiting

An Automated Navigation System for Deep Brain Electrode Implantation

Refractory Epilepsy | Obsessive-compulsive Disorder | Advanced Parkinson's Disease

China
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Rewards for Tuberculosis Contact Screening (RECON)

Tuberculosis | Drug-resistant Tuberculosis

South Africa
National Institute of Mental Health (NIMH)

Completed

(18F)FCWAY and the Blood-Brain Barrier

Drug Resistance

United States
Hospital Ruber Internacional
Zogenix, Inc.

Recruiting

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes (FENDEEP)

Refractory Epilepsy | STXBP1 Encephalopathy With Epilepsy | SYNGAP1 Encephalopathy | Inv Dup(15) Encephalopathy | Multifocal or Bilateral Malformations of Cortical Development | Continuous Spike and Waves During Slow Sleep

Spain
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in Mali

Tuberculosis, Pulmonary | Mycobacterium Tuberculous | Antitubercular Agents | Tuberculosis, Mulutidrug-Resistant | Extensively Drug-Resistant | Extensibely Drug-Resistant Tuberculosis

United States, Mali
National Institute of Allergy and Infectious Diseases...

Completed

Linezolid to Treat Extensively-Drug Resistant Tuberculosis

Pulmonary Tuberculosis | Multidrug Resistant Tuberculosis | Extensively Drug Resistant Tuberculosis

Korea, Republic of
Epicentre
Medecins Sans Frontieres, Netherlands

Completed

Evaluation of PCR Using DNA Extract From Slides and Filter Paper for the Detection of Tuberculosis and MDR-tuberculosis

Tuberculosis | Multi Drug Resistant Tuberculosis

Uganda
Janssen Infectious Diseases BVBA

Withdrawn

A Study to Evaluate the Efficacy and Safety of TMC207 in Patients With Pulmonary Infection With Multi-drug Resistant Mycobacterium Tuberculosis

Multi-drug Resistant Tuberculosis

China, Ukraine, Taiwan, Korea, Republic of, Peru, Brazil, Estonia, Latvia, Philippines, Russian Federation, South Africa, Thailand, Turkey, Georgia, Mexico, Cambodia, Ethiopia
Institut National de la Santé Et de la Recherche...

Unknown

Episodic Memory Before and After Surgery in Drug-resistant Partial Epilepsies (MemO-Epi)

Memory Impairment | Epilepsy, Unspecified, Pharmacologically Resistant

France
IRCCS Eugenio Medea

Recruiting

Structural-functional Connectome in Drug-resistant Epilepsies and Neurodevelopmental Syndromes With Epilepsy

Epilepsy | Angelman Syndrome | Dup15q Syndrome

Italy
Assistance Publique - Hôpitaux de Paris

Recruiting

New Genomic Techniques and Management of Multidrug-resistant Tuberculosis (GENO-MDR)

Multi-Drug Resistant Tuberculosis

France
Medstar Health Research Institute

Unknown

Prevalence and Level of Thienopyridine Resistance Seen in a Contemporary Percutaneous Coronary Intervention or Coronary Artery Bypass Graft Population (VASP)

Increased Drug Resistance

United States
National Institute of Allergy and Infectious Diseases...

Completed

Tuberculosis in China

Tuberculosis | Tuberculosis, Multidrug-Resistant | Extensively Drug Resistant Tuberculosis

China
Janssen Research & Development, LLC

Completed

A Prospective Patient Registry of Patients Exposed to Bedaquiline

Pulmonary Multi-drug Resistant Tuberculosis

United States
The Methodist Hospital Research Institute
M.D. Anderson Cancer Center; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

Antibiotic Resistant Infection | Clostridium Difficile | Antimicrobial Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin Resistant Enterococci Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection | Extended Spectrum Beta-Lactamase...

United States
University Hospital, Akershus
Oslo University Hospital; Helse Stavanger HF; Sorlandet Hospital HF; Sykehuset... and other collaborators

Terminated

Fecal ESBL Resurgence During Antibiotic Treatment

Antibiotic Drug Resistance
Centre Hospitalier Universitaire de Besancon

Completed

Prevalence of ESBL-producing Enterobacteriaceae as Carbapenem-resistant Enterobacteriaceae in Nursing Homes. (R'EHPAD)

Drug Resistance, Bacterial

France
Hospices Civils de Lyon

Not yet recruiting

Helium 4 Optically Pumped Magnetometers : a New Generation of Sensors for High Speed Functional Brain Imaging (NEW MEG)

Normal Subject | Patient With Pharmaco-resistant Epilepsy

France
Massachusetts Institute of Technology
McGill University; United States Agency for International Development (USAID); Kehea... and other collaborators

Completed

Behavior Change and Digital Health Interventions for Improved TB Treatment Outcomes

Tuberculosis | Adherence, Medication | Drug-resistant Tuberculosis | Adherence, Patient

Kenya
Centers for Disease Control and Prevention
Columbia University; New York City Department of Health and Mental Hygiene

Completed

An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment

Tuberculosis | Adherence, Medication | Drug-resistant Tuberculosis | Adherence, Patient

United States
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
Catholic University of the Sacred Heart
University Hospital, Geneva; Universiteit Antwerpen; Clinical Centre of Serbia; Canisius-Wilhelmina Hospital and other collaborators

Unknown

SATURN 04 Nosocomial Acquisition Study (SATURN)

Infection Due to ESBL Bacteria | Bacterial Resistance | Infection Resistant to Multiple Drugs | Staph Aureus Methicillin Resistant Colonization

Italy, Romania, Serbia
Tourcoing Hospital

Recruiting

Prognostic Factors and Therapeutic Management of ESBL Enterobacteriaceae in the ICU (BLSE-REA)

Drug Resistance, Multiple, Bacterial

France
Global Alliance for TB Drug Development

Completed

A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
Global Alliance for TB Drug Development

Completed

Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States

Clinical Trials on Drug-Resistant Epilepsy

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