Clinical Trials on EBV-Related Leiomyosarcoma

Total 51728 results

Viracta Therapeutics, Inc.

Recruiting

Nanatinostat Plus Valganciclovir in Patients With Advanced EBV+ Solid Tumors, and in Combination With Pembrolizumab in EBV+ RM-NPC

Nasopharyngeal Carcinoma | EBV-Related Gastric Carcinoma | EBV-Related Leiomyosarcoma | EBV Related Carcinoma | EBV-Related Sarcoma

United States, Hong Kong, Taiwan, Korea, Republic of, Singapore, Australia, Canada, Malaysia
Baylor College of Medicine
The Methodist Hospital Research Institute

Recruiting

EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma (CILESTE)

EBV-Related Hodgkin Lymphoma | EBV Related Non-Hodgkin's Lymphoma | EBV-Related Lymphoproliferative Disorder

United States
Atara Biotherapeutics

Recruiting

A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases

Lymphoproliferative Disorders | Leiomyosarcoma | Stem Cell Transplant Complications | Solid Organ Transplant Complications | Epstein-Barr Virus (EBV)-Associated Diseases | EBV+ Post-transplant Lymphoproliferative Disease (EBV+ PTLD) | Allogeneic Hematopoietic Cell Transplant | EBV+ Sarcomas | EBV+ Lymphoproliferative... and other conditions

United States, Austria, Belgium, France, Italy, Spain, United Kingdom
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Nivolumab With Epstein Barr Virus Specific T Cells (EBVSTS), Relapsed/Refractory EBV Positive Lymphoma (PREVALE) (PREVALE)

Lymphoproliferative Disorders | Hodgkin Lymphoma | EBV Related Non-Hodgkin's Lymphoma | NonHodgkin Lymphoma | EBV-Related PTLD | EBV Related Lymphoma | EBV Related Hodgkin's Lymphoma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Locally Advanced Leiomyosarcoma | Metastatic Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Leiomyosarcoma | Uterine Corpus Leiomyosarcoma

United States
Viracta Therapeutics, Inc.

Recruiting

An Open-Label, Phase 2 Trial of Nanatinostat in Combination With Valganciclovir in Patients With Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory Lymphomas (NAVAL-1)

EBV Related Non-Hodgkin's Lymphoma | Epstein-Barr Virus Associated Lymphoproliferative Disorder | EBV-Related PTLD | EBV Associated Lymphoma | EBV-Positive DLBCL, NOS | EBV Related PTCL, NOS

United States, Spain, Italy, United Kingdom, Singapore, Taiwan, Korea, Republic of, Germany, Canada, Brazil, Australia, France, Malaysia, Hong Kong, Israel
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Uterine Corpus Leiomyosarcoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

Metastatic Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Leiomyosarcoma | Stage IIIA Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IIIB Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IIIC Uterine Corpus Leiomyosarcoma... and other conditions

United States
Catherine Bollard

Active, not recruiting

Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma (ALCI2)

Hodgkin Disease | Non Hodgkin Lymphoma | Leiomyosarcoma | Lymphoepithelioma | Severe Chronic Active EBV Infection Syndrome (SCAEBV)

United States
National Cancer Institute (NCI)

Suspended

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Locally Advanced Uterine Corpus Leiomyosarcoma | Metastatic Uterine Corpus Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Uterine Corpus Leiomyosarcoma

United States, Puerto Rico
Atara Biotherapeutics

No longer available

Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia or Malignancies

Lymphoproliferative Disorders | Stem Cell Transplant Complications | Epstein-Barr Virus (EBV) Infections | EBV+ Associated Lymphoma | EBV+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD) | Epstein-Barr Viremia | Lymphoma, AIDS-related | Epstein-Barr Virus-associated Lymphoproliferative... and other conditions
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study of Doxorubicin and Trabectedin in First Line Treatment on Patients With Metastatic Leiomyosarcoma (LMS02)

Uterus Leiomyosarcoma | Soft Tissue Leiomyosarcoma

France
National Cancer Institute (NCI)

Active, not recruiting

A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Uterine Corpus Leiomyosarcoma

United States
Hebei Yanda Ludaopei Hospital
China Immunotech (Beijing) Biotechnology Co., Ltd.

Completed

EBV-TCR-T Cells for EB Virus Infection After HSCT

EBV Emia and EBV Positive PTLD After Allogenic HSCT

China
Kristen Ganjoo

Recruiting

CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma

Uterine Leiomyosarcoma | LMS - Leiomyosarcoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); EMD Serono

Terminated

Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Metastatic Liposarcoma | Unresectable Liposarcoma

United States
Massachusetts General Hospital
Jazz Pharmaceuticals

Recruiting

Lurbinectedin + Doxorubicin In Leiomyosarcoma

Advanced Soft-tissue Sarcoma | Metastatic Soft-tissue Sarcoma | Advanced Leiomyosarcoma | Leiomyosarcoma Metastatic

United States
David Liebner, MD

Withdrawn

Niraparib for the Treatment of Leiomyosarcoma

Locally Advanced Leiomyosarcoma | Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Stage III Retroperitoneal Sarcoma AJCC v8 | Stage IIIA Retroperitoneal Sarcoma AJCC v8 | Stage IIIB Retroperitoneal Sarcoma AJCC v8 | Stage IV Retroperitoneal Sarcoma AJCC v8

United States
GOG Foundation

Recruiting

Letrozole in Uterine Leiomyosarcoma

Uterine Leiomyosarcoma

United States
Gachon University Gil Medical Center
Merck KGaA, Darmstadt, Germany; Chong Kun Dang Pharmaceutical Corp.

Recruiting

Avelumab in Combination With Gemcitabine in Advanced Leiomyosarcoma as a Second-line Treatment (EAGLES)

Leiomyosarcoma Metastatic

Korea, Republic of
National Cancer Institute (NCI)

Recruiting

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Metastatic Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Unresectable Sarcoma

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Sintilimab in Combination With R-CHOP in Patients With Treatment-naive EBV-positive DLBCL, NOS

EBV-Positive DLBCL, Nos

China
Memorial Sloan Kettering Cancer Center

Withdrawn

Safety and Effectiveness of EBV-specific Cytotoxic T Cells for the Treatment for EBV Lymphomas or Other EBV-associated Malignancies

EBV Lymphomas | EBV-associated Malignancies
National Cancer Institute (NCI)

Terminated

Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma

High Grade Sarcoma | Metastatic Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Leiomyosarcoma | Myxofibrosarcoma | Metastatic Malignant Peripheral Nerve Sheath Tumor | Metastatic Synovial Sarcoma | Metastatic Undifferentiated... and other conditions

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma (LMS04)

Uterine or Soft Tissue Leiomyosarcoma

France
Institut Bergonié
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt...

Recruiting

Targeting ATR in Soft-tissue Sarcomas (TARSARC)

Leiomyosarcoma, Adult

France
Italian Sarcoma Group
PharmaMar

Recruiting

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma (ISG-ARTICLE)

Soft Tissue Sarcoma | Leiomyosarcoma of Ovary

Italy
Sarcoma Alliance for Research through Collaboration

Completed

SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic Leiomyosarcoma

Metastatic Leiomyosarcoma

United States
Gynecologic Oncology Group
GlaxoSmithKline

Withdrawn

Pazopanib for Treating Uterine Leiomyosarcoma

Uterine Leiomyosarcoma
Janssen Research & Development, LLC
PharmaMar

Completed

A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma

Advanced Liposarcoma or Leiomyosarcoma

United States, Australia, Brazil, New Zealand
The Hospital for Sick Children
University of British Columbia; Canadian Institutes of Health Research (CIHR); Centre hospitalier de l'Université de Montréal (CHUM) and other collaborators

Completed

CNTRP POSITIVE Study

Medication Adherence | Transplant | EBV | PTLD | Adaptive Immunity

Canada
Xian-Janssen Pharmaceutical Ltd.

Completed

A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma

Advanced or Metastatic Liposarcoma or Leiomyosarcoma

China
Chinese PLA General Hospital

Recruiting

Clinical Study of EBV-TCR-T Cells for EBV Infection After Allogenic HSCT

EBV Infection After Allogenic HSCT

China
North Eastern German Society of Gynaecological...
Novartis Pharmaceuticals; medac GmbH

Active, not recruiting

Pazopanib vs. Pazopanib Plus Gemcitabine (PazoDoble)

Leiomyosarcoma or Carcinosarcoma

Germany
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery

Uterine Corpus Leiomyosarcoma | Stage I Uterine Sarcoma AJCC v7

United States, Belgium, France, Spain, United Kingdom, Netherlands, Norway, Venezuela
Atara Biotherapeutics
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center

Completed

Biological Therapy in Treating Patients at High-Risk or With Lymphoma, Lymphoproliferative Disease, or Malignancies

EBV-induced Lymphomas | EBV-associated Malignancies | Transplant Patients With EBV Viremia at High Risk of Developing a Recurrent EBV Lymphoma

United States
Nantes University Hospital

Unknown

Cell Bank of Epstein Barr Virus Specific Cytotoxic T Lymphocytes

EBV Associated Lymphoma

France
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Sunitinib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus

Recurrent Uterine Sarcoma | Uterine Leiomyosarcoma

United States
Broto, Javier Martín, M.D.

Unknown

Trial of Nilotinib and Adriamycin as Treatment in Liposarcomas and Leiomyosarcomas of Retroperitoneum (GEIS-27)

Chondrosarcoma | Retroperitoneal Liposarcoma | Retroperitoneal Leiomyosarcoma

Spain
Atara Biotherapeutics
Memorial Sloan Kettering Cancer Center

Completed

Therapeutic Effects of Epstein-Barr Virus Immune T-Lymphocytes Derived From a Normal HLA-Compatible Or Partially-Matched Third-Party Donor in the Treatment of EBV Lymphoproliferative Disorders and EBV-Associated Malignancies

EBV-induced Lymphomas | EBV-associated Malignancies | Transplant Patients With EBV Viremia at High Risk for Developing a Recurrent EBV Lymphoma

United States
Yonsei University
Merck KGaA, Darmstadt, Germany

Active, not recruiting

K-Basket, Avelumab, Biomarker-driven, Advanced Solid Tumor

PD-L1 Positive Mutation Tumor | EBV Positive Mutation Tumor | MSI-H Mutation Tumor | POLE/POLD1 Mutation Tumor

Korea, Republic of
National Cancer Institute (NCI)
NRG Oncology

Completed

Alisertib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Ixabepilone in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus Previously Treated With Chemotherapy

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States
Catherine Bollard

Active, not recruiting

Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)

CMV | EBV | Adenovirus

United States
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation in Children

Completed

Biomarkers for Post-Transplant Lymphoproliferative Disorders in Children

Liver Transplant | Kidney Transplant | Heart Transplant | EBV-Related PTLD | Small Intestine Transplant | PTLDs

United States
West China Second University Hospital

Active, not recruiting

Comparison Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine Fibroids

Uterine Sarcoma | Uterine Fibroid | Uterine Leiomyosarcoma

China
Memorial Sloan Kettering Cancer Center

Completed

Adjuvant Docetaxel Plus Gemcitabine in Patients With Completely Resected Leiomyosarcoma (LMS) of the Uterus

Uterine Cancer | Uterine Leiomyosarcoma

United States
Tongji Hospital
Kousai Bio Co., Ltd.

Enrolling by invitation

KSD-101 Therapy for EBV-associated Haematologic Neoplasms: an Exploratory Clinical Trial

EBV-associated Haematologic Neoplasms

China
Igenomix

Recruiting

Accuracy of the Preoperative Molecular Diagnosis of Uterine Tumors by Liquid Biopsy (MYOSARCII)

Leiomyoma, Uterine | Leiomyosarcoma Uterus

Spain
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Filgrastim or Pegfilgrastim in Treating Patients With Recurrent or Persistent Cancer of the Uterus

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States

Clinical Trials on EBV-Related Leiomyosarcoma

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