Clinical Trials on ERK Mutation in United States
Total 859 results
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Providence Health & ServicesRecruitingBRAF V600E Mutation Present | Stage IV Differentiated Thyroid Gland Carcinoma AJCC v8 | Refractory Thyroid Gland Carcinoma | Metastatic Thyroid Gland Carcinoma | BRAF NP_004324.2:p.V600M | Stage IVA Differentiated Thyroid Gland Carcinoma AJCC v8 | Stage IVB Differentiated Thyroid Gland Carcinoma...United States
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Asklepios Biopharmaceutical, Inc.RecruitingMuscular Dystrophy | Limb Girdle Muscular Dystrophy | LGMD2I | LGMD | Limb-Girdle Muscular Dystrophy Type 2 | LGMD2 | FKRP | FKRP Mutation | Fukutin Related ProteinUnited States
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Masonic Cancer Center, University of MinnesotaActive, not recruitingTriple Negative Breast Cancer | HER2-positive Breast Cancer | TN ER-/PR-/HER2- Breast Cancer | ERany/PRany/HER2+ Breast CancerUnited States
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC... and other conditionsUnited States
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Haihe Biopharma Co., Ltd.RecruitingC-Met Exon 14 MutationChina, Japan, United States
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Verastem, Inc.RecruitingMetastatic Cancer | Pancreas Cancer | Neoplasms Pancreatic | KRAS Activating Mutation | Malignant Neoplasm of PancreasUnited States
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PfizerTerminatedDilated Cardiomyopathy | Lamin A/C Gene MutationUnited States, Spain, Canada, Belgium, Italy, Argentina, Mexico, Netherlands, Norway, United Kingdom
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Ruth O'ReganUniversity of Rochester; Puma Biotechnology, Inc.RecruitingBreast Cancer | HER2-positive Breast Cancer | ER Positive Breast Cancer | PR-Positive Breast CancerUnited States
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Axogen CorporationRecruitingAmputation | Symptomatic Neuroma | Chronic Nerve PainUnited States
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Kimberly N SchubertCompletedAggression | Trichotillomania | Substance Use | Gambling | Deliberate Self-harm | Stealing | Eating PathologyUnited States
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Verastem, Inc.AmgenRecruitingNon Small Cell Lung Cancer | KRAS Activating MutationUnited States, Spain, France, United Kingdom, Netherlands, Belgium
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Arog Pharmaceuticals, Inc.RecruitingRelapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating MutationsUnited States, Germany, Spain, Italy, France, Canada
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M.D. Anderson Cancer CenterRecruitingMyelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myeloproliferative Neoplasm | Acute Myeloid Leukemia With Gene MutationsUnited States
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI)Active, not recruitingVemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive CraniopharyngiomaBRAF V600E Mutation Present | Papillary CraniopharyngiomaUnited States
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Novartis PharmaceuticalsNo longer availableAcute Myeloid Leukemia (AML) With | FLT3 Mutation, Internal Tandem Duplication (ITD) or Tyrosine Kinase Domain (TKD)United States
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Ascentage Pharma Group Inc.Merck Sharp & Dohme LLCRecruitingMelanoma | P53 Mutation | Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma | Malignant Peripheral Nerve Sheath Tumors | MPNST | Unresectable or Metastatic Melanoma or Advanced Solid Tumors | MDM2 Gene MutationUnited States, Australia
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Novartis PharmaceuticalsTerminatedMyelofibrosis With High Molecular Risk MutationsBelgium, Spain, United Kingdom, Hungary, Italy, Japan, Taiwan, Germany, Canada, Singapore, Austria, Australia, France, Israel, Sweden, Switzerland, Hong Kong, Greece, Turkey, Brazil, Russian Federation, Denmark, Portugal, Norway, Poland
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingChronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | IDH2 Gene Mutation | Acute Bilineal Leukemia | Acute Biphenotypic LeukemiaUnited States
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M.D. Anderson Cancer CenterActive, not recruitingGenetic Mutation | MEN1United States
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New York Stem Cell Foundation Research InstituteSilverstein FoundationRecruitingHealthy | Parkinson Disease | Gaucher Disease | GBA Gene MutationUnited States
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University of California, DavisNational Cancer Institute (NCI); Merck Sharp & Dohme LLC; NovartisActive, not recruitingKRAS Gene Mutation | Stage IV Non-Small Cell Lung Cancer AJCC v7 | Recurrent Non-Squamous Non-Small Cell Lung Carcinoma | Metastatic Non-Squamous Non-Small Cell Lung CarcinomaUnited States
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Icahn School of Medicine at Mount SinaiRecruitingPancreatitis | Chronic Pancreatitis | Pancreas Cancer | Pancreatic Cyst | Genetic Mutations | Family History of Pancreas CancerUnited States
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University of SussexCompletedCellulitis | Cellulitis of Leg | Antibiotic DurationUnited Kingdom
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Johns Hopkins UniversityThe Plastic Surgery FoundationEnrolling by invitationPhantom Limb Pain | Pain, Neuropathic | Amputation NeuromaUnited States
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University of WashingtonEunice Kennedy Shriver National Institute of Child Health and Human Development...CompletedMultiple Sclerosis | Chronic Pain | Amputation | Spinal Cord InjuryUnited States
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Xiuning LeM.D. Anderson Cancer Center; Eli Lilly and CompanyActive, not recruitingNon Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | EGFR Gene MutationUnited States
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Novartis PharmaceuticalsTerminatedAdvanced or Metastatic ER+ Breast CancerUnited States, France, Germany, Singapore, Italy, Japan, Belgium
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Massachusetts General HospitalGilead SciencesRecruitingTriple Negative Breast Cancer | Invasive Breast Cancer | HER2-negative Breast Cancer | ER-Negative Breast Cancer | PR-Negative Breast CancerUnited States
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National Cancer Institute (NCI)RecruitingMesothelioma | Familial Cancer | BRCA1-Associated Protein-1 (BAP1) Mutations | Tumor Predisposition Syndrome (TPDS)United States
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National Heart, Lung, and Blood Institute (NHLBI)RecruitingCardiovascular Disease | Arterial Stiffness | Germline Mutation in the NOTCH 3 Gene | Pathogenesis of CADASIL | Clinical Phenotype of CADASILUnited States
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Sidney Kimmel Cancer Center at Thomas Jefferson...National Cancer Institute (NCI)CompletedFollicular Lymphoma | Myeloid Leukemia | Polycythemia Vera | Hodgkin Lymphoma | Myelofibrosis | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Chronic Lymphocytic Leukemia | Secondary Acute Myeloid Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Refractory... and other conditionsUnited States
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Mayo ClinicAstellas Pharma Inc; Casimir, LLCCompletedMitochondrial Diseases | Mitochondrial Myopathies | Kearns-Sayre Syndrome | Mitochondrial DNA Mutation | Chronic Progressive External Ophthalmoplegia With MyopathyUnited States
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University of PennsylvaniaMemorial Sloan Kettering Cancer Center; Susan G. Komen Breast Cancer FoundationEnrolling by invitationOvarian Cancer | BRCA MutationUnited States
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National Cancer Institute (NCI)RecruitingMesothelioma | BRCA1-Associated Protein-1 (BAP1) Mutations | Malignant Mesothelioma (MM) | Early-stage Mesothelioma | Subclinical Mesothelioma | Early-stage BAP1-associated MalignanciesUnited States
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University of LeicesterRecruitingAmputation | Physical Disability | Vascular Disease, PeripheralUnited Kingdom
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Hull University Teaching Hospitals NHS TrustUniversity of HullCompletedWound Infection | Amputation WoundUnited Kingdom
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Orthocare Innovations, LLCNational Institute on Disability, Independent Living, and Rehabilitation...RecruitingStroke | Upper Limb Amputation | Upper Limb Weakness Due to Central Neurologic Injury | Upper Limb Weakness Due to Peripheral Neurologic Injury | Upper Limb Weakness Due to Nerve Reconstruction | Upper Limb Weakness Due to Tendon Transfer SurgeryUnited States
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Hunter Holmes Mcguire Veteran Affairs Medical CenterCompletedChronic Pain | Postoperative Pain | Amputation | Acute Pain | Phantom Limb Pain | Neuroma | Residual LimbsUnited States
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Washington University School of MedicineSuspendedDiabetes Mellitus | Peripheral Arterial Disease | Critical Limb Ischemia | Lower Limb Amputation KneeUnited States
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Inspirna, Inc.RecruitingGastrointestinal Neoplasms | Colorectal Neoplasms | Gastric Cancer | Colorectal Cancer | Colorectal Cancer Metastatic | Gastrointestinal Cancer | Colorectal Carcinoma | CRC | KRAS Mutation-Related Tumors | Gastric NeoplasmUnited States
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Astellas Pharma Global Development, Inc.Active, not recruitingAcute Myeloid Leukemia (AML) | Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) MutationUnited States, Japan, Taiwan, Spain, Australia, Belgium, Canada, France, Germany, Italy, Korea, Republic of, Poland, United Kingdom
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Columbia UniversityNational Institute on Aging (NIA)RecruitingLumbar Spinal Stenosis | Cardiomyopathy, Hypertrophic | Cardiac Amyloidosis | ATTR Amyloidosis Wild Type | ATTR Gene Mutation | ATTRV122I AmyloidosisUnited States
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Turning Point Therapeutics, Inc.TerminatedNon-Small Cell Lung Cancer | NSCLC | Non Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | ALK Gene MutationUnited States, Australia, Korea, Republic of
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New York State Psychiatric InstituteCompletedDepression | Bipolar Disorder | Self-Injurious Behavior | Borderline Personality Disorder | Self Harm | Non-Suicidal Self Injury | Self Injurious Behavior Without Suicidal Intent | Self-inflicted Injury | Self-injury | Non Suicidal Self Inflicted Injury | CuttingUnited States
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Syndax PharmaceuticalsCompleted
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Seagen Inc.CompletedTriple Negative Breast Neoplasms | Hormone Receptor Positive Breast Neoplasms | HER2 Positive Breast Neoplasms | HER2 Mutations Breast NeoplasmsUnited States
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Astellas Pharma Global Development, Inc.CompletedAcute Myeloid Leukemia (AML) | Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) / Internal Tandem Duplication (ITD) MutationTaiwan, Poland, Serbia, United States, Brazil, Canada, Czechia, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Portugal, Romania, Spain, Sweden, United Kingdom
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Massachusetts General HospitalPuma Biotechnology, Inc.; Celcuity, Inc.WithdrawnMetastatic Breast Cancer | Invasive Breast Cancer | HER2-negative Breast Cancer | ER Positive Breast Cancer | PR-Positive Breast Cancer | Stage IV (Metastatic) Breast CancerUnited States
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Calithera Biosciences, IncTerminatedNon-GCB/ABC Diffuse Large B-Cell Lymphoma | With and Without MyD88 and/or CD79B MutationsUnited States
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University of ArkansasWithdrawnPancreatic Neoplasms | Colorectal Neoplasms, Hereditary Nonpolyposis | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Hereditary Pancreatitis | Ataxia Telangiectasia | Peutz-Jegher's Syndrome | Familial Atypical Mole-Malignant Melanoma SyndromeUnited States