Clinical Trials on Early Age Related Macular Degeneration (Disorder) in United Kingdom

Total 1542 results

Royal Liverpool University Hospital

Unknown

Macular Function During Anti-VEGF Treatment (MAFAT)

Age Related Macular Degeneration

United Kingdom
OKKO Health

Recruiting

OKKO Health Hyperacuity, Contrast and Colour Game Validation in Age-related Macular Degeneration

Age-Related Macular Degeneration

United Kingdom
Pfizer

Terminated

A Study Of Early Markers Of Choroidal Neovascularization

Age-related Macular Degeneration (AMD) | Choroidal Neovascularization (CNV) | Early Markers

Italy, Portugal, United Kingdom
Second Sight Medical Products

Completed

Argus II Retinal Prosthesis System Dry AMD Feasibility Study Protocol

Age Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust

Completed

VITAL - Individualising Therapy for Neovascular AMD With Aflibercept (VITAL)

Age Related Macular Degeneration

United Kingdom
OKKO Health
Nottingham University Hospitals NHS Trust; Oxford University Hospitals NHS... and other collaborators

Enrolling by invitation

Patient-centred Smartphone AI for Protecting Vision in Macular Disease

Age-Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust

Completed

Defining Disease Activity in Neovascular AMD With Optical Coherence Tomography Angiography (DANA)

Neovascular Age-related Macular Degeneration

United Kingdom
Queen's University, Belfast

Completed

Development of Core Outcomes for Age-related Macular Degeneration (AMD) Interventions- Caregivers' Perspective

Age Related Macular Degeneration

United Kingdom
King's College Hospital NHS Trust
King's College London

Completed

A Pharmacokinetic Study: Ranibizumab, Aflibercept and the Effect of Vitrectomy. (VITCLEAR)

Age Related Macular Degeneration

United Kingdom
Brighton and Sussex University Hospitals NHS Trust

Completed

Ocular Coherence Tomography During Cataract Assessment

Age Related Macular Degeneration | Cataract Senile | Epiretinal Membrane | Vitreomacular Traction | Macula Hole

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
University College, London

Recruiting

A Study Of Implantation Of Retinal Pigment Epithelium In Subjects With Acute Wet Age Related Macular Degeneration

Age Related Macular Degeneration

United Kingdom
Maastricht University Medical Center
Cognis Deutschland GmbH & Co. KG

Completed

The Influence of Lutein Supplements on Age-related Macular Degeneration

Age-Related Macular Degeneration

Netherlands, United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
British Eye Research Foundation, operating as Fight for Sight

Completed

EFFECT:Eccentric Fixation From Enhanced Clinical Training (EFFECT)

Age Related Macular Degeneration (ARMD)

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust

Not yet recruiting

Retinal Pigment Epithelium Safety Study For Patients In B4711001

Age Related Macular Degeneration

United Kingdom
Aston University
The Dunhill Medical Trust

Completed

Colour Contrast Sensitivity for the Early Detection of Wet Age-related Macular Degereration (CEDAR) (CEDAR)

Age Related Macular Degeneration

United Kingdom
Newtricious R&D BV
Sprim Advanced Life Sciences

Completed

Intervention Trial in Early Age-related Macular Degeneration (I-TEAM)

Age-related Macular Degeneration (AMD)

United States, Germany, Netherlands, United Kingdom
Novartis Pharmaceuticals

Terminated

The Efficacy of Oral Everolimus in Patients With Neovascular Age-related Macular Degeneration

Age-related Macular Degeneration | Choroidal Neo-Vascular Age-onset Macular Degeneration

United Kingdom, United States
Azienda Ospedaliera Universitaria Mater Domini,...

Recruiting

Photobiomodulation in Dry Age Related Macular Degeneration (DRUSEN)

Age-Related Macular Degeneration

France, Italy, Turkey, United Kingdom
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan, United Kingdom
Notal Vision Inc.

Completed

Single In-Clinic Encounter With the Notal Vision Home OCT

Neovascular Age-related Macular Degeneration | Intermediate Age Related Macular Degeneration (Disorder)

United States
Bayer
Regeneron Pharmaceuticals

Terminated

A Study to Learn How Well Aflibercept Injected Into the Eye Works and How Safe it is When Given in Customized Treatment Intervals in Patients With an Eye Disease Called Neovascular Age-related Macular Degeneration After Start of Treatment (XPAND)

Neovascular (Wet) Age-related Macular Degeneration

Canada, United Kingdom
Bayer

Completed

Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease (XTEND)

Wet Age-related Macular Degeneration

Canada, Spain, Sweden, Belgium, Argentina, Italy, Korea, Republic of, United Kingdom, China, Denmark, France, Norway, Colombia, Australia, Ireland, Switzerland, Thailand
Oraya Therapeutics, Inc.

Withdrawn

Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV)

Macular Degeneration | Age-related Macular Degeneration | AMD | Wet AMD | Wet Age-related Macular Degeneration

United Kingdom, Italy
Moorfields Eye Hospital NHS Foundation Trust

Completed

Optimising Visual Acuity Measurement in Macular Degeneration (OPTIMISE)

Age Related Macular Degeneration

United Kingdom
Novartis Pharmaceuticals

Terminated

Brolucizumab Treatment Experience Study of Patients With nAMD in UK Routine Clinical Practice (BESRA)

Neovascular Age-related Macular Degeneration

United Kingdom
LumiThera, Inc.

Completed

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE II)

Dry Age-related Macular Degeneration

United Kingdom, Spain, France, Germany, Italy
VisionCare, Inc.

Recruiting

Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular Degeneration

Age-Related Macular Degeneration | AMD

Italy, Ireland, Spain, Germany, United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
King's College London; Cardiff University; University College, London; Newcastle... and other collaborators

Recruiting

Quality-Assured Follow-up of Quiescent Neovascular Age -Related maculaR dEgeneration by Non-medical Practitioners (FENETRE)

AMD

United Kingdom
Novartis Pharmaceuticals

Terminated

A Prospective, Observational, Multicentre, 2 Year Study Evaluating the Use of Eylea (Aflibercept) for the Treatment of Neovascular (Wet) Age-related Macular Degeneration in UK NHS Opthalmology Clinics

Wet Age-related Macular Degeneration

United Kingdom
Novartis

Completed

Safety and Tolerability of an Intravenous Infusion of ACZ885 in Patients With Wet Age-Related Macular Degeneration

Wet Age-Related Macular Degeneration

United Kingdom, Switzerland
Frank G. Holz
Radboud University Medical Center; Bayer; Hoffmann-La Roche; Novartis Pharmaceuticals and other collaborators

Active, not recruiting

Development of Novel Clinical Endpoints in Intermediate AMD (MACUSTAR)

Age Related Macular Degeneration (AMD)

Germany, Italy, Netherlands, United Kingdom, France, Portugal, Denmark
Duke University
Bausch & Lomb Incorporated

Completed

Neovascular Morphology and Persistent Disease Activity Among Patients With NV AMD

Neovascular Age-Related Macular Degeneration

United States
Subhransu K. Ray, M.D., Ph.D.
Bay Area Retina Associates

Completed

A Prospective Study Comparing Ranibizumab Plus Dexamethasone Combination Therapy Versus Ranibizumab Monotherapy for Wet AMD (Lucedex)

Exudative Age-Related Macular Degeneration

United States
Retina Macula Institute

Completed

Study Investigating OCT, Multifocal ERG, and Microperimetry in Monthly Versus PRN Ranibizumab in Neovascular Age-Related Macular Degeneration

Neovascular Age Related Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

Study of the Safety of Brolucizumab 6 mg in Prefilled Syringe in Patients With Neovascular Age Related Macular Degeneration

Neovascular Age Related Macular Degeneration

United States
Manhattan Eye, Ear & Throat Hospital
Alcon Research

Completed

Study of the Combination of Anecortave Acetate and Triamcinolone Acetonide for the Treatment of Exudative Age-Related Macular Degeneration (AMD)

Maculopathy, Age-Related

United States
Ocugenix Corporation

Not yet recruiting

Safety and Tolerability of OCU-10-C-110 for Injection in Subjects With Neovascular Age-related Macular Degeneration

Neovascular Age-related Macular Degeneration (nAMD)

United States
Johns Hopkins University

Completed

NVAMD Satellite Study

Neovascular Age Related Macular Degeneration

United States
Regeneron Pharmaceuticals

Completed

Safety and Tolerability of Intravitreal VEGF Trap Formulations in Subjects With Neovacular AMD

Neovascular Age Related Macular Degeneration

United States
Iconic Therapeutics, Inc.

Completed

Safety and Tolerability Study for Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Ocular Therapeutix, Inc.
Duke University; Fortrea

Recruiting

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Prefilled Syringe

Neovascular Age-related Macular Degeneration (nAMD)

United States
Ocular Therapeutix, Inc.

Completed

Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Apellis Pharmaceuticals, Inc.

Completed

Assessment of Safety, Tolerability and Pharmacokinetics of Intravitreal Pegcetacoplan (APL-2) for Patients With Wet AMD (ASAP II)

Neovascular Age-Related Macular Degeneration

United States, Australia
REGENXBIO Inc.

Completed

Safety and Tolerability of RGX-314 (Investigational Product) Gene Therapy for Neovascular AMD Trial

Neovascular Age-related Macular Degeneration | Wet Age-related Macular Degeneration

United States
Hoffmann-La Roche

Recruiting

Extension Study for the Port Delivery System With Ranibizumab (Portal) (Portal)

Neovascular Age-Related Macular Degeneration

Belgium, United States, United Kingdom, Italy, Argentina, Spain, Israel, Australia, Austria, Brazil, Germany, Switzerland, Taiwan, France
Hoffmann-La Roche

Recruiting

A Study of the Efficacy, Safety, and Pharmacokinetics of A 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

Neovascular Age-related Macular Degeneration (nAMD)

Belgium, Korea, Republic of, Germany, Spain, United Kingdom, Australia, Italy, Argentina, Israel, Austria, Brazil, France, Singapore, Switzerland, Taiwan, Turkey
King's College Hospital NHS Trust
King's College London

Active, not recruiting

Stereotactic Radiotherapy for Wet AMD (STAR) (STAR)

Neovascular (Wet) Age-related Macular Degeneration (AMD)

United Kingdom
University of Miami
Genentech, Inc.

Completed

Prospective OCT Study With Lucentis for Neovascular AMD (PrONTO Study)

Neovascular Age-Related Macular Degeneration

United States
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Vial Kit

Neovascular Age-related Macular Degeneration (nAMD)

United States

Clinical Trials on Early Age Related Macular Degeneration (Disorder) in United Kingdom

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