Clinical Trials on Early Esophageal Squamous Neoplasia

Total 5740 results

Nang Kuang Pharmaceutical Co., Ltd.

Terminated

A Phase II Trial of Induction Chemotherapy With ND-420, Cisplatin and Fluorouracil Followed by Surgery in the Treatment of Patients With Localized Squamous Cell Carcinoma of the Esophagus

Localized Squamous Cell Carcinoma of the Esophagus

Taiwan
Yonsei University

Unknown

A Trial to Evaluate the Efficacy of Poziotinib, Pan HER Inhibitor in Recurrent/Metastatic Esophageal Cancer (R/M ESCC)

Inoperable or Recurrent or Metastatic Esophageal Squamous Carcinoma

Korea, Republic of
Affiliated Hospital of Nantong University

Recruiting

PD-1 Inhibitor Combined With Radiotherapy for Elderly ESCC

Esophageal Squamous Cell Carcinoma

China
Chuangzhen Chen

Completed

Study of Simultaneous Modulated Accelerated Radiation Therapy Concurrent With Chemotherapy to Treat Esophageal Cancer

Esophageal Neoplasms

China
Beijing Friendship Hospital

Unknown

Chemoprevention of Esophageal Squamous Cell Carcinoma (ESCC) With Aspirin and Tea Polyphenols (CREAT)

Carcinoma, Squamous Cell

China
Shandong Luye Pharmaceutical Co., Ltd.

Unknown

A Clinical Trial of a Radiation Sensitizer in Radiochemotherapy for Thoracic Esophageal Squamous Carcinoma

Esophageal Carcinoma

China
Mayo Clinic
National Cancer Institute (NCI)

Completed

Endoscopic Therapy of Early Cancer in Barretts Esophagus

Barrett Esophagus | Early Stage Esophageal Adenocarcinoma

United States
Sichuan Cancer Hospital and Research Institute

Recruiting

Outcomes of Smoker and Drinker With Esophageal Squamous Cell Carcinoma After Esophagectomy (OSinEC)

Outcomes of Smoker and Drinker After Esophagectomy

China
Fudan University

Active, not recruiting

Phase II Study of Postoperative Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESO- Shanghai 17)

Esophageal Squamous Cell Carcinoma | Esophagus Cancer | Postoperative | Chemoradiotherapy | Radiation Therapy

China
Fudan University
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Perioperative Sintilimab and Chemotherapy in Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Peking University

Not yet recruiting

Pembrolizumab and Photodynamic Therapy in Previously Treated Metastatic Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Chang Gung Memorial Hospital
Tianjin Medical University Cancer Institute and Hospital; Shanghai Chest Hospital

Recruiting

Robotic-assisted Esophagectomy vs. Video-Assisted Thoracoscopic Esophagectomy(REVATE) Trial

Esophageal Squamous Cell Carcinoma

Taiwan
Sichuan Cancer Hospital and Research Institute
Shanxi Province Cancer Hospital; Xiangya Hospital of Central South University; Wuhan University and other collaborators

Completed

Chemoradiotherapy With or Without Enteral Nutrition for Locally Advanced Thoracic Esophageal Carcinoma

Esophageal Squamous Cell Carcinoma | Chemoradiotherapy | Enteral Nutrition Therapy

China
Hebei Medical University Fourth Hospital

Not yet recruiting

Clinical Research on the Effect of Aspirin on the Disease Free Survival Rate of Esophageal Carcinoma

Aspirin as an Adjuvant Therapy, to Observe Its Effect on the Disease Free Survival Rate of Patients With Esophageal Squamous Cell Carcinoma

China
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes

Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage I Lung Cancer AJCC v8 | Stage IA1 Lung Cancer AJCC v8 | Stage IA2 Lung Cancer AJCC v8 | Stage IA3 Lung Cancer... and other conditions

United States
Samsung Medical Center

Unknown

Efficacy Comparison Study of Combination Regimens to Treat Advanced Esophageal Squamous Cell Carcinoma (XP versus XT)

First Line Chemotherapy | Capecitabine Plus Cisplatin Versus Capecitabine Plus Paclitaxel | Advanced or Recurrent Esophageal Squamous Cell Carcinoma

Korea, Republic of
AP Biosciences Inc.

Not yet recruiting

A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies (APT-CUBE)

Esophageal Squamous Cell Carcinoma (ESCC) | Locally Advanced or Metastatic Solid Tumors | Non Small Cell Lung Cancer (NSCLC) | Head and Neck Squamous Cell Carcinoma (HNSCC)
University Health Network, Toronto

Active, not recruiting

Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy (MASST)

Cancer | Metastatic Cancer | Squamous Cell Carcinoma of the Head and Neck | Anal Canal Squamous Cell Carcinoma | Esophagus Squamous Cell Carcinoma

Canada
Qilu Hospital of Shandong University

Withdrawn

Neoadjuvant Immunotherapy to ESCC

Esophagus SCC

China
Xiaomeng Zheng

Enrolling by invitation

A Clinical Study of Non-curative Resection Plus Radiotherapy After Endoscopic ESD for Superficial Esophageal Squamous Cell Carcinoma

Radiotherapy | Esophagus Cancer | Endoscopic Mucosal Resection

China
Centre Hospitalier Universitaire Dinant Godinne...

Recruiting

Treatment of Early Supraglottic Squamous Cell Carcinoma With Advance Technologies (SUPRA-QoL)

Supraglottic Squamous Cell Carcinoma | Early Stage (T1-T2, N0-N1,M0)

Belgium
Yonsei University

Unknown

A Phase II Trial of Afatinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of Esophagus

Squamous Cell Carcinoma of Esophagus

Korea, Republic of
Fudan University
RenJi Hospital; Shanghai Chest Hospital; Shanghai General Hospital, Shanghai... and other collaborators

Unknown

Chemoradiation With or Without Nimotuzumab in Treating Esophageal Cancer Patients Who Suffer With Recurrence in Regional Lymph Nodes After Esophagectomy (Nimotuzumab)

Esophageal Squamous Cell Carcinoma

China
Sun Yat-sen University

Recruiting

Combination of Cadonilimab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-006) (EC-CRT-006)

Esophagus Cancer

China
Shandong University

Completed

Artificial Intelligence for Early Diagnosis of Esophageal Squamous Cell Carcinoma

Artificial Intelligence | Optical Enhancement Endoscopy | Magnifying Endoscopy

China
iOMEDICO AG

Recruiting

Registry Platform Gastric/Esophageal Cancer (SAPHIR) (SAPHIR)

Gastric Adenocarcinoma | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Gastroesophageal Junction Adenocarcinoma

Germany
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Adenocarcinoma of the Gastroesophageal Junction | Stage II Gastric Cancer | Stage III Gastric Cancer | Squamous Cell Carcinoma of the Esophagus | Adenocarcinoma of the Stomach | Adenocarcinoma of the Esophagus | Stage III Esophageal Cancer | Stage II Esophageal Cancer

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study of Docetaxel for Injection (Albumin-bound) and SG001 in Combination With Cisplatin and Simultaneous Radiotherapy for Locally Advanced Unresectable Esophageal Squamous Carcinoma.

Locally Advanced Unresectable Esophageal Squamous Carcinoma

China
Erasmus Medical Center

Not yet recruiting

Feasibility and Added Value of the TRACMOTION Device for ESD (TRACMOTION)

Oesophageal Neoplasm
Weijia Fang, MD
Akeso Pharmaceuticals, Inc.

Recruiting

Neoadjuvant Treatment of Cadonilimab Combined Albumin-paclitaxel, Cisplatin and Fluorouracil for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

The Efficacy and Safety of Therapy Efficacy for Locally Advanced ESCC

China
Guangdong Provincial People's Hospital

Recruiting

Patient-reported Outcomes in Preoperative Immunochemotherapy/Radiotherapy-treated Esophageal Cancer Patients (PICCRT)

Esophageal Squamous Cell Carcinoma | Immunotherapy | Patient-reported Outcomes

China
Tianjin Medical University Cancer Institute and...
Sichuan Cancer Hospital and Research Institute; Chinese Academy of Medical...

Completed

Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
Sun Yat-sen University

Unknown

Concurrent Radiotherapy and Weekly Chemotherapy of PF for Postoperative Locoregional Recurrence of Esophageal Cancer

Esophageal Squamous Cell Carcinoma

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Tislelizumab in Combination With Chemotherapy for Conversion Therapy of Locally Nonresectable ESCC

Esophageal Squamous Cell Carcinoma | Locally Advanced Carcinoma

China
Yuhong Li

Completed

Study of Icotinib Hydrochloride in Treating Patients With Recurrent or Metastatic Esophageal Cancer After Failure of Conventional Chemotherapy

Esophageal Squamous Cell Carcinoma

China
Morten Mau-Sørensen
Odense University Hospital; Aarhus University Hospital; Aalborg University Hospital

Recruiting

Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma Patients (HERES)

Esophageal Squamous Cell Carcinoma | HER-2 Gene Amplification | HER-2 Protein Overexpression

Denmark
National Taiwan University Hospital
Merck Sharp & Dohme LLC

Active, not recruiting

Adjuvant Pembrolizumab for Patients With Locally Advanced Esophageal Squamous Cell Carcinoma at High Risk of Recurrence

Esophageal Squamous Cell Carcinoma

Taiwan
Centre Oscar Lambret
National Cancer Institute, France

Terminated

Benefit of Chemotherapy Over Best Supportive Care in Metastatic and Squamous Cell-type Esophageal Cancer. (E-DIS)

Squamous Cell Carcinoma of Esophagus

France
Nanfang Hospital of Southern Medical University

Recruiting

Immune Indicator Model for Predicting Efficacy of PD-1 Monoclonal Antibody

Esophageal Squamous Cell Carcinoma | PD-1 Inhibitor

China
Shanghai Cancer Hospital, China

Recruiting

Influence of Radiotherapy and Chemotherapy in the Value of Peripheral Blood Lymphocyte Subsets Among Thoracic Cancer

NSCLC | Thymic Epithelial Tumor | Esophageal Squamous Cell Carcinoma

China
Centre of Postgraduate Medical Education
Maria Sklodowska-Curie National Research Institute of Oncology

Not yet recruiting

Early Detection of Esophageal Squamous Cancer With the Capsule Sponge Device (ANGELA)

Head and Neck Cancer | Esophageal Cancer | Squamous Cell Carcinoma
Fudan University
Shanghai Zhongshan Hospital

Completed

Primary Tumor Burden Score:A Novel Staging Parameter for ESCC After nCRT

Neoplasm, Esophagus | Neoplasm, Squamous Cell
Shanghai Zhongshan Hospital

Unknown

The Cohort Study of Early Esophageal Cancer or Precancerous Lesions Treated With Endoscopic Resection

Early Esophageal Cancer or Precancerous Lesions Treated With Endoscopic Resection
Novartis Pharmaceuticals

Completed

A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer

Squamous Cell Carcinoma of Head and Neck | Esophageal Squamous Cell Carcinoma | HER2 + Breast Cancer, HER2 + Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma | HER2 + Breast Cancer | HER2 + Gastric Cancer

Taiwan, Spain, Canada, Korea, Republic of, United States
VA Office of Research and Development
VA Palo Alto Health Care System; VA Puget Sound Health Care System; Michael E... and other collaborators

Not yet recruiting

A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Gastroesophageal Junction Carcinoma

United States
Anhui Provincial Hospital

Recruiting

Hybrid Dose-fraction Radiotherapy for Metastatic Non-small Cell Lung Cancer

Esophageal Squamous Cell Carcinoma

China
Merus N.V.

Recruiting

A Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR and Anti-c-MET Bispecific Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Non-Small Cell Lung Cancer Metastatic

United States, Spain, France, Italy, Netherlands, Belgium, Korea, Republic of, Germany, Singapore
Sinocelltech Ltd.

Unknown

Study of SCT-I10A Combined SCT200 or SCT-I10A Combined SCT200 Plus Chemotherapy in ESCC and CRC

Colorectal Cancer | Esophageal Squamous Cell Carcinoma
Jacobio Pharmaceuticals Co., Ltd.
AbbVie

Recruiting

JAB-3068 Activity in Adult Patients With Advanced Solid Tumors

Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma

China
Yonsei University

Active, not recruiting

Study to Evaluate Efficacy of PDR001 in Patients With Squamous Cell Carcinoma of the Esophagus

Histologically Confirmed Unresectable or Metastatic Squamous Cell Carcinoma of the Esophagus Who Failed on Standard Treatment

Korea, Republic of

Clinical Trials on Early Esophageal Squamous Neoplasia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations