Clinical Trials on Early Intervention

Total 1735 results

Fudan University

Recruiting

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy (FASCINATE-N)

Breast Cancer | Breast Neoplasm | Breast Tumors | HER2-positive Breast Cancer | Locally Advanced Breast Cancer | HER2-negative Breast Cancer | Hormone Receptor Positive Tumor | Hormone Receptor Negative Tumor | Early-stage Breast Cancer | Triple-Negative Breast Cancer (TNBC)

China
University of Miami
Columbia University; National Institute on Aging (NIA); Case Western Reserve... and other collaborators

Recruiting

Genetic Studies in Familial Dementia

Dementia | Mild Cognitive Impairment | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | Dementia of Alzheimer Type

United States
Mednax Center for Research, Education, Quality...
Banner University Medical Center

Completed

A Chart Review of Newborns With the Presence of Confirmed or Suspected Maternal Chorioamnionitis and Utilization of the Early Onset Sepsis Calculator

Maternal; Chorioamnionitis, Affecting Fetus | Early-Onset Sepses, Neonatal

United States
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Completed

Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2)

Mild Cognitive Impairment (MCI) | Alzheimer's Disease (AD) | Significant Memory Concern (SMC) | Early Mild Cognitive Impairment (EMCI) | Late Mild Cognitive Impairment (LMCI)

United States, Canada
Peking University First Hospital
Rainmed Ltd., Suzhou, China

Recruiting

The Flash FFR Ⅱ Study

Coronary Artery Disease | Percutaneous Coronary Intervention | Stable Angina Pectoris | Unstable Angina Pectoris | Coronary Stenosis | Acute Myocardial Infarction | Myocardial Ischaemia | Coronary Circulation | Asymptomatic Ischemia

China
Johns Hopkins University

Completed

Extinction Learning in Adults With Tourette Syndrome

Tourette Syndrome | Tic Disorders | Tics | Habit Reversal Training | Comprehensive Behavioral Intervention for Tics

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

To Compare the Efficacy and Safety of Oral SHR 7280 Tablets With Ganirelix Acetate Injection in Infertile Female Subjects

Infertile Female Subjects Undergoing Controlled Ovarian Hyperstimulation to Suppress Premature LH Surge and Prevent Early Ovulation

China
Novartis Pharmaceuticals

Completed

A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam in Early Manifest Huntington's Disease (VIBRANT-HD)

Early Manifest Huntington Disease

Canada, Germany, France, Spain, Hungary
University of Calgary

Recruiting

Strength Training for Osteoporosis Prevention During Early Menopause (STOP-EM)

Musculoskeletal Diseases | Osteoporosis | Bone Loss | Bone Loss, Age-related

Canada
University Hospital, Lille

Completed

Patients With Alzheimer's Disease or Related Youth Disease (PARMAAJJ)

Lewy Body Disease | Frontotemporal Lobar Degeneration | Alzheimer Disease, Early Onset

France
St George's, University of London
MRC/UVRI and LSHTM Uganda Research Unit; MU-JHU CARE

Active, not recruiting

Serosurveillance Study of Maternally Derived Anti-GBS Antibody (ProGreSs)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

Uganda
Janssen Research & Development, LLC

Completed

A Study to Characterize the Clinical Course of Pregnant Women and Children at High Risk for Early Onset Severe Hemolytic Disease of the Fetus and Newborn

Erythroblastosis, Fetal | Early Onset Severe Hemolytic Disease of the Fetus and Newborn (EOS-HDFN)

United States, Canada, Netherlands, Belgium, Australia, Germany, Spain, Sweden, United Kingdom
St George's, University of London
MRC/UVRI and LSHTM Uganda Research Unit; MU-JHU CARE

Completed

Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital (PREPARE)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

Uganda
Morten Lindbaek
Norwegian Institute of Public Health; Sorlandet Hospital HF; Norwegian University...

Completed

Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice (NorTick_EM)

Lyme Disease | Erythema Migrans | Erythema Chronicum Migrans | Borreliosis | Early Lyme Disease

Norway
Erasmus Medical Center

Recruiting

PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions (PRESENT)

Coronary Artery Disease | Stable Angina | Percutaneous Coronary Intervention | Unstable Angina | Multi Vessel Coronary Artery Disease | Non-ST Elevation Myocardial Infarction | Optical Coherence Tomography

Netherlands
Rhode Island Hospital
National Institute on Drug Abuse (NIDA)

Completed

Brief Intervention for Drug Misuse in the Emergency Department (BIDMED)

HIV Infections | Hepatitis B | Hepatitis C | HIV | Substance Abuse Detection | Brief Intervention

United States
Stamford Anesthesiology Services, PC
I-Flow

Unknown

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

Ambulatory Surgical Procedures | Adult | Humans | Abdominal Muscles/Ultrasonography | Anesthetics, Local/Administration & Dosage | Ropivacaine/Administration & Dosage | Ropivacaine/Analogs & Derivatives | Nerve Block/Methods | Pain Measurement/Methods | Pain, Postoperative/Prevention & Control | Ultrasonography... and other conditions

United States
Xiuli Zuo

Active, not recruiting

Artificial Intelligence for Determination of Gastroscopy Surveillance Intervals

Early Gastric Cancer | Gastric Cancer | Helicobacter Pylori Infection | Intestinal Metaplasia | Atrophic Gastritis | Low Grade Intraepithelial Neoplasia | High Grade Intraepithelial Neoplasia

China
Imperial College London

Not yet recruiting

Improving Mental Health Following Early PREgnancy Loss Using a Brief Cognitive Task (IMPREL)

Miscarriage | Post-traumatic Stress Disorder | Ectopic Pregnancy | Pregnancy Loss | Trauma, Psychological
Nelly Pitteloud

Recruiting

GnRH Therapy on Cognition in Down Syndrome

Down Syndrome | Cognitive Decline | Alzheimer Disease, Early Onset | Olfaction Disorders

Switzerland
McGill University
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Recruiting

DOvEEgene: Diagnosing Ovarian and Endometrial Cancer Early Using Genomics (DOvEEgene)

Ovarian Neoplasms | Ovarian Cancer | Endometrial Neoplasms | Endometrial Cancer | Safety | Early Diagnosis | Screening | Reduced Mortality | Reduced Morbidity

Canada
Sunnybrook Health Sciences Centre
Merck Canada Inc.

Active, not recruiting

In the Era of the HPV Vaccine, What Are The Current HPV Subtypes Contributing to High Grade Cervical Dysplasia, Adenocarcinoma in Situ, and Early Cervical Cancer?

HSIL, High-Grade Squamous Intraepithelial Lesions | Adenocarcinoma in Situ | Early Cervical Cancer

Canada
Michael Morowitz
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

NICU Antibiotics and Outcomes Trial (NANO)

Microbial Colonization | Late-Onset Neonatal Sepsis | Necrotizing Enterocolitis of Newborn | Extreme Prematurity | Death; Neonatal | Early-Onset Neonatal Sepsis

United States, Canada
QuantumLeap Healthcare Collaborative

Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer (I-SPY)

Breast Cancer | Breast Neoplasms | Breast Tumors | HER2-positive Breast Cancer | Angiosarcoma | Locally Advanced Breast Cancer | HER2-negative Breast Cancer | TNBC - Triple-Negative Breast Cancer | Hormone Receptor Positive Tumor | Hormone Receptor Negative Tumor | Early-stage Breast Cancer

United States
European Organisation for Research and Treatment...

Terminated

REACH: Study to Determine the Aetiology of Chlormethine Gel Induced-skin Drug Reaction in Early Stage Mycosis Fungoides Cutaneous T Cell Lymphoma (MF-CTCL) (REACH)

Early Stage Mycosis Fungoides Cutaneous T Cell Lymphoma (MF-CTCL) (Stage IA-IB)

France
Martin-Luther-Universität Halle-Wittenberg
University of Leipzig; Jena University Hospital; St. Elisabeth Hospital Halle

Completed

Multimodal Monitoring of Fetal Risk of Inflammation in Preterm Premature Rupture of Membranes (MuMFI-PPROM)

Preterm Premature Rupture of Membranes | Early Onset Neonatal Sepsis | Fetal Inflammatory Response Syndrome | Infection of Amniotic Cavity

Germany
Lei Li

Unknown

Non-coding RNA in the Exosome of the Epithelia Ovarian Cancer

Ovarian Cancer | High Grade Serous Carcinoma | Prognosis | Early Diagnosis | Exosomes

China
St George's, University of London
Assistance Publique - Hôpitaux de Paris; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Recruiting

Serocorrelate of Protection Against GBS (PREPARE WP3)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

France, Italy, Malawi, Netherlands, Uganda, United Kingdom
Boston Children's Hospital

Recruiting

Genetics of Epilepsy and Related Disorders

Epilepsy | Dravet Syndrome | Infantile Spasms | Epileptic Encephalopathy | Ohtahara Syndrome | Early Myoclonic Epileptic Encephalopathy | PCDH19-related Epilepsy and Related Conditions | KCNQ2-Related Epileptic Encephalopathy | Epilepsy of Infancy With Migrating Focal Seizures (Disorder)

United States
Vanderbilt University Medical Center
National Institutes of Health (NIH); National Institute of General Medical...

Active, not recruiting

Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study (INSIGHT-ICU)

Delirium | Critical Illness | Cognitive Impairment | Trauma | Traumatic Brain Injury | ICU | Polytrauma | Alzheimer; Early Onset

United States
Heidelberg Engineering GmbH

Completed

Repeatability of Static & Dynamic Composite Confocal Microscopy for Assessment of the Corneal Nerve Fiber Plexus in Early Diabetic Polyneuropathy

Normal Eyes of Subjects Without Diabetes Mellitus | Subjects With Diabetes Mellitus Type 2 Without Coexisting DPN | Subjects With Diabetes Mellitus Type 2 With Coexisting Early to Moderate DPN
Centre Hospitalier Universitaire de Besancon
Assistance Publique - Hôpitaux de Paris; Centre Hospitalier Universitaire Dijon

Unknown

tDCS Effect on Cognitive Functions From Patients With Alzheimer's Disease or Progressive Primary Aphasia (ALSTICO)

Alzheimer's Disease | Progressive Primary Aphasia | Early or Mild State

France
Mayo Clinic
National Institute on Aging (NIA)

Recruiting

Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study

Alzheimer Disease | Alzheimer Disease, Early Onset | Amnestic Mild Cognitive Disorder | Atypical Alzheimer's Disease | Logopenic Progressive Aphasia (LPA) | Posterior Cortical Atrophy (PCA) | Amnestic Disorder | Amnestic Symptoms

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Mindfulness Meditation or Survivorship Education in Improving Behavioral Symptoms in Younger Stage 0-III Breast Cancer Survivors (Pathways to Wellness) (PTW)

Stage 0 Breast Cancer | Cancer Survivor | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Early-Stage Breast Carcinoma | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer

United States
University of Utah

Completed

Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit

Post-operative Craniotomy Patients | Carotid Endarterectomy and Carotid Artery Stenosis Patients | Post-op Spine Patients Admitted to the NCCU | Endovascular Patients Undergoing Intracranial Intervention | Traumatic Brain Injuries NPO for at Least 12 Hours

United States
University of British Columbia
Unity Health Toronto; University of Calgary; Queen's University; Ottawa Heart Institute... and other collaborators

Completed

Registry of Unexplained Cardiac Arrest

Cardiac Arrest | Early Repolarization Syndrome | Brugada Syndrome | Long QT Syndrome | Arrhythmogenic Right Ventricular Cardiomyopathy | Catecholaminergi Polymorphic Ventricular Tachycardia | Idiopathic VentricularFibrillation

Canada
University of Erlangen-Nürnberg Medical School
Siemens-Betriebskrankenkasse

Terminated

Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the Early Menopause

Coronary Disease | Bone Diseases | Metabolic Syndrome X

Germany
Pamlab, Inc.
InfoMedics, Inc.

Completed

NAC-003 P.L.U.S. Program (Progress Through Learning Understanding & Support)

Mild Cognitive Impairment | Vascular Dementia | Alzheimer's Disease | Early Memory Loss

United States
Universidade do Porto
Instituto Portugues de Oncologia, Francisco Gentil, Porto; Unidade de Saúde... and other collaborators

Recruiting

HPV Self-sampling for Women Who do Not Attend Cervical Cancer Screening Programme (HERSELF)

Papillomavirus Infections | Cervix Cancer | Early Detection of Cancer | Self-Examination

Portugal
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Radiomics Markers to Predict Sepsis Induced Acute Respiratory Distress Syndrome

Early Prediction for Sepsis Induced Acute Lung Injury

China
Indian Council of Medical Research
King George's Medical University; Lady Hardinge Medical College; King Edward... and other collaborators

Not yet recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates (SAUNA)

Sepsis | Preterm Birth | Preterm Premature Rupture of Membrane | PROM, Preterm (Pregnancy) | Early-Onset Neonatal Sepsis

India
Boston Children's Hospital
CureAP4 Foundation

Recruiting

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP)

Hereditary Spastic Paraplegia | SPG50 | SPG47 | SPG51 | SPG52 | AP4-related Hereditary Spastic Paraplegia | Early Onset Hereditary Spastic Paraplegia | SPG4 | SPG3A | SPG15 | SPG11

United States
Centre Hospitalier Universitaire de Saint Etienne
Association Lyonnaise de Logistique Posthospitalière

Terminated

Sleep Apnea in Early to Mid-Stage Alzheimer's Disease (AZAP)

Alzheimer Disease | Early Onset Alzheimer Disease | Obstructive Sleep Apnea Syndromes

France
SINA Health Education and Welfare Trust
Aga Khan University

Not yet recruiting

Effectiveness of Educational Intervention on Footcare Among Individuals Having Type 2 Diabetes at Slums of Karachi, Pakistan.

Diabetic Foot | Foot Ulcer, Diabetic | Educational Intervention | Foot Care | Foot Cellulitis
University of North Carolina, Greensboro

Completed

Rhythmically Entrained Exercise in Community-Dwelling Older Adults (REECO)

Depression | Cognitive Impairment | Cognitive Dysfunction | Dementia | Alzheimer Disease | Exercise | Caregiver Burden | Healthy Aging | Fall | Mild Cognitive Impairment | Elderly | Executive Function | Gait | Mental Health | Cognitive Decline | Memory Disorders | Memory Impairment | Walking | Cognition | Physical Exertion | Music Therapy and other conditions

United States
Peking University Third Hospital

Not yet recruiting

Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries

Low Back Pain | Lumbar Disc Herniation | Radiculopathy | Lumbar Spinal Stenosis | Radicular Pain | 3D Printing Guide Plate | Lumbosacral Facet Joint Syndrome | Ischemic Pain of the Lower Extremity | Spinal Minimally Invasive and Interventional Surgeries

China
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Mortality in Sickle Cell | Sickle Cell Cardiopulmonary Complications | Sickle Cell Organ Damage | Sickle Cell Life Expectancy and Risk Factors for Early Death | Sickle Cell Lung Disease and Sudden Death

United States
AstraZeneca

Completed

Nexium Capsules Helicobacter Pylori Specific Clinical Experience Investigation

Early Gastric Cancer | Gastric Ulcer | Duodenal Ulcer | Gastric Mucosa-associated Lymphoid Tissue (MALT) | Lymphoma Idiopathic Thrombocytopenic Purpura

Japan
Cognito Therapeutics, Inc.

Active, not recruiting

Study of Tolerability, Safety and Efficacy of Sensory Stimulation at Multiple Dose Levels to Improve Brain Function (Etude Study)

Cognitive Impairment | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | Dementia, Alzheimer Type | Memory Disorders | Memory Impairment | Alzheimer Dementia | Memory Loss | Dementia, Mild | Memory Disorders, Age Related

United States
University of Southern California
National Institute on Aging (NIA); Huntington Hospital

Completed

Social Work Intervention Focused on Transitions (SWIFT)

Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention

United States

Clinical Trials on Early Intervention

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zimbabwe

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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