Clinical Trials on Echinococcosis, Hepatic

Total 3182 results

Novartis Pharmaceuticals

Completed

Pharmacokinetics (PK) of TKI258 in Cancer Patients With Normal and Impaired Hepatic Function

Hepatic Impairment | Solid Tumors

Belgium, Germany, Netherlands, Italy, Singapore, United States
M.D. Anderson Cancer Center

Unknown

Understanding Patient's Knowledge and Use of Acetaminophen

Liver Failure

United States
ObsEva SA

Completed

Safety and Pharmacokinetics Study of Linzagolix in Female Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment | Healthy Participants

United States
Takeda

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Healthy Volunteers | Hepatic Impairment

Czechia, Slovakia
Sahlgrenska University Hospital, Sweden

Completed

Inflammation and Organ Impact During Hepatic Surgery

Hepatic Surgery

Sweden
Merck Sharp & Dohme LLC
Celerion

Completed

The Influence of Hepatic Insufficiency on the Pharmacokinetics of Elbasvir (MK-8742) (MK-8742-009)

Hepatic Insufficiency

United States
Hospital Italiano de Buenos Aires

Completed

Interstage Assessment of Remnant Liver Function in ALPPS

Liver Failure

Argentina
AstraZeneca

Completed

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Solid Tumors

United States
Conatus Pharmaceuticals Inc.

Completed

PK and PD Study of IDN-6556 in Subjects With Hepatic Impairment and Matched Healthy Volunteers

Liver Diseases | Digestive System Diseases | Hepatic Impairment

United States
Boehringer Ingelheim

Completed

Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy Volunteers

Hepatic Insufficiency

Germany
Bristol-Myers Squibb

Completed

Single-Dose Pharmacokinetics of BMS-790052 in Participants With Hepatic Impairment

Hepatic Insufficiency

United States
Veloxis Pharmaceuticals
CTI Clinical Trial and Consulting Services; Aptuit

Completed

Pharmacokinetics of LCP-Tacro™ Once Daily and Prograf® Twice A Day in Adult De Novo Liver Transplant Patients

Liver Failure

United States
Boehringer Ingelheim

Completed

Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency

Hepatic Insufficiency
Baxter Healthcare Corporation
Baxter Innovations GmbH

Completed

Fibrin Sealant VH S/D 500 S-apr in Hepatic Resection

Bleeding (Oozing) in Hepatic Resection

Germany
University Hospital, Gentofte, Copenhagen

Completed

Pharmacokinetics of 9-cis-retinoic Acid (Alitretinoin, Toctino®) in Patients With Hepatic Disease

Hepatic Insufficiency

Denmark
Universitaire Ziekenhuizen KU Leuven

Unknown

Citrate Anticoagulation During MARS Treatment

Liver Failure

Belgium
Novartis

Completed

Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function

Hepatic Insufficiency

United States
Kowa Company, Ltd.

Completed

Study of Peretinoin for Suppressing Recurrence of HCV-positive HCC

Hepatic Neoplasm Malignant Recurrent

Japan
Eli Lilly and Company

Recruiting

A Study of LY3437943 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
PharmaMar

Recruiting

Clinical Pharmacokinetic Study of Lurbinectedin in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Impairment

Hepatic Impairment | Advanced Solid Tumor

Spain
Incyte Corporation

Completed

To Evaluate the Safety, and Pharmacokinetics of Parscaclisib in Participants With Normal Hepatic Function and Hepatic Impairment.

Advanced Malignancies

United States
Loma Linda University

Completed

Hepatitis C Virus (HCV) Positive Liver Grafts in HCV Negative Recipients

Liver Failure

United States
Boehringer Ingelheim

Completed

A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems

Hepatic Insufficiency | Healthy

United States
Tongji Hospital

Unknown

A Study on Nutrition Support Therapy of Patients With Liver Failure

Nutrition
University Hospital, Grenoble

Recruiting

Description of Lactulose Administration by Balloon Rectal Tube in Severe Hepatic Encephalopathy (ALPACA)

Hepatic Encephalopathy

France
University of Michigan
Winterlight Labs

Active, not recruiting

Speech in Hepatic Encephalopathy (HE)

Hepatic Encephalopathy

United States
Abbott

Completed

A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]

Hepatic Encephalopathy

India
Assiut University

Unknown

Plasma Free Amino Acids in Patients With Hepatic Encephalopathy

Hepatic Encephalopathy
Abbott
Dimension Research

Completed

Minimal HePatic Encephalopathy Among CiRrhotics. A Cross SEctional, Clinico-EpidEmiological, Multi-Centre, Study in Patients of PakisTan (Preempt)

Hepatic Encephalopathy

Pakistan
Sherief Abd-Elsalam

Unknown

PEG (Polyethylene Glycol)Versus Lactulose For Treatment Of Overt Hepatic Encephalopathy

Hepatic Encephalopathy

Egypt
Ain Shams University
Al-Azhar University

Unknown

The Effects of Nitazoxanide in Hepatic Encephalopathy

Hepatic Encephalopathy

Egypt
Hunter Holmes Mcguire Veteran Affairs Medical Center

Completed

A Study of Controlled Lactulose Withdrawal

Hepatic Encephalopathy

United States
Govind Ballabh Pant Hospital

Unknown

Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in Cirrhotics

Hepatic Encephalopathy

India
Aga Khan University

Unknown

Lactulose for the Prevention of Hepatic Encephalopathy in Cirrhotic Patients With Upper Gastrointestinal Hemorrhage

Encephalopathy, Hepatic | Hepatocerebral Encephalopathy | Portal-Systemic Encephalopathy | Encephalopathy, Hepatocerebral

Pakistan
Mylan Specialty, LP

Terminated

Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning

Liver Failure | Amatoxin Poisoning | Amanita Poisoning | Mushroom Poisoning

United States
Alnylam Pharmaceuticals

Terminated

INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP

Acute Hepatic Porphyria | Acute Intermittent Porphyria (AIP) | Hereditary Coproporphyria (HCP) | Variegate Porphyria (VP) | ALA Dehydratase Deficient Porphyria (ADP) | Hepatic Porphyrias | Porphyria Acute

United States
Eli Lilly and Company

Recruiting

A Study of LY3502970 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Bristol-Myers Squibb

Recruiting

A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

Hepatic Insufficiency | Neoplasms

Spain, United States, Germany, Argentina, Colombia, Greece
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Liver Function and Healthy Participants

Hepatic Insufficiency | Healthy

United States
Mochida Pharmaceutical Company, Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Clinical Pharmacology of FYU-981 (Subjects With Hepatic Insufficiency)

Hepatic Insufficiency | Healthy

Japan
Boehringer Ingelheim

Completed

Pharmacokinetics of Empagliflozin (BI 10773) in Patients With Impaired Liver Function

Hepatic Insufficiency | Healthy

Romania
Eli Lilly and Company

Completed

A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function

Hepatic Insufficiency | Healthy

United States
Genfit
University of Miami; Syneos Health

Completed

Elafibranor Pharmacokinetic Parameters in Hepatic Impaired Patients

Pharmacokinetics | Hepatic Impairment | Liver Disease

United States
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Pharmacokinetics of Tivantinib in Subjects With Advanced Solid Tumors and Hepatic Impairment

Cancer | Solid Tumor | Hepatic Impairment

United States
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017)

Hepatic Insufficiency | Insomnia
Ono Pharma USA Inc
Ono Pharmaceutical Co. Ltd

Completed

An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment

Healthy | Hepatic Impairment

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Canagliflozin in Study Participants With Various Degrees of Impaired Hepatic (Liver) Function

Hepatic Insufficiency | Healthy

United States
Carol Davila University of Medicine and Pharmacy

Recruiting

Predictive Values of Presepsin Levels in ASciteS in Patients With Chronic Liver Failure (PASS)

Liver Failure | Cirrhosis, Liver | Ascites Hepatic

Romania
Power Life Sciences Inc.

Not yet recruiting

Revealing Engagement Patterns Among Hepatic Encephalopathy Patients

Hepatic Encephalopathy

United States
Ain Shams University

Recruiting

Efficacy of L-Ornithine L-Aspartate (LOLA) as an Adjunct to Branched Chain Amino Acids (BCAA) Enriched Solutions on Clinical Outcomes in ICU Patients With Hepatic Encephalopathy

Hepatic Encephalopathy

Egypt

3

Subscribe