Clinical Trials on Edema Due to Heart Failure or Cirrhosis in United Kingdom

Total 376 results

GlaxoSmithKline

Completed

A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients

Oedema, Pulmonary

United Kingdom
Heartfelt Technologies
Royal Brompton & Harefield NHS Foundation Trust

Completed

Feasibility Study of a New Peripheral Oedema Monitor for Heart Failure

Heart Failure, Diastolic | Edema Brain | Decompensated Heartfailure

United Kingdom
University of Maryland, Baltimore

Completed

Gingival Augmentation Around Implants During Maintenance

Failure of Dental Implant Due to Lack of Attached Gingiva

United States
Echosense Ltd.

Completed

Changes in Doppler Signals From the Lung Due to Cardiac Resynchronization in Heart Failure Patients

Change in LDS Signals Due to Cardiac Synchronization Therapy

United States
Ascension Health

Withdrawn

Prophylactic Lisinopril to Prevent Anthracycline Cardiomyopathy.

Heart Failure, Systolic | Cardiomyopathy Due to Drug

United States
National Institute of Diabetes and Digestive and...
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Cancer... and other collaborators

Recruiting

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States (LCN RESCU)

Cirrhosis | Cirrhosis, Liver | Cirrhosis Due to Hepatitis B | Cirrhosis Due to Hepatitis C | Cirrhosis Early | Cirrhosis Advanced | Cirrhosis Infectious | Cirrhosis Alcoholic | Cirrhosis, Biliary | Cirrhosis Cryptogenic | Cirrhosis Due to Primary Sclerosing Cholangitis

United States
Northwestern University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Cancer... and other collaborators

Recruiting

Liver Cirrhosis Network Cohort Study (LCN-C)

Cirrhosis | Cirrhosis, Liver | Cirrhosis Due to Hepatitis B | Cirrhosis Due to Hepatitis C | Cirrhosis Early | Cirrhosis Advanced | Cirrhosis Infectious | Cirrhosis Alcoholic | Cirrhosis, Biliary | Cirrhosis Cryptogenic | Cirrhosis Due to Primary Sclerosing Cholangitis

United States
Gilead Sciences

Terminated

Simtuzumab (SIM, GS-6624) in the Treatment of Cirrhosis Due to NASH (NASH)

Liver Fibrosis Due to NASH

United States, Canada, France, Italy, Germany, Puerto Rico, Spain, United Kingdom
Reproductive Science Center

Unknown

Use of Adiana Tubal Occlusive Devices in Women With Hydrosalpinx Prior to In Vitro Fertilization

Women Suffering From Unilateral or Bilateral Tubal Occlusion Due to Hydrosalpinx

United States
Heartfelt Technologies
Torbay and South Devon NHS Foundation Trust

Completed

Foot Oedema Observed Over Time Study (FOOT)

Heart Failure | Edema Leg

United Kingdom
Manchester University NHS Foundation Trust
Medical Research Council; British Heart Foundation

Completed

Transdermal Fluid Removal in Fluid Overload

Heart Failure | Odema

United Kingdom
GlaxoSmithKline

Completed

Evaluation of MRI Measures of Lung Water With Posture Changes in Healthy Volunteers and in Patients With Cardiac Failure

Heart Failure, Congestive

United Kingdom
Orthocare Innovations, LLC
National Institute on Disability, Independent Living, and Rehabilitation...

Recruiting

mGain - sEMG-based Gamified Therapy for Improved Upper Limb Rehabilitation

Stroke | Upper Limb Amputation | Upper Limb Weakness Due to Central Neurologic Injury | Upper Limb Weakness Due to Peripheral Neurologic Injury | Upper Limb Weakness Due to Nerve Reconstruction | Upper Limb Weakness Due to Tendon Transfer Surgery

United States
GlaxoSmithKline

Completed

A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure

Heart Failure, Congestive

United Kingdom
The University of Texas Health Science Center,...
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Injection in Cancer Survivors (SENECA)

Cardiomyopathy Due to Anthracyclines

United States
Theravance Biopharma

Completed

TD-1607 SAD Study in Healthy Subjects

Serious Infections Due to Known or Suspected Gram-positive Pathogens

United States
Queen Mary University of London
CVRx, Inc.

Terminated

UK Registry for Baroreflex Activation Therapy (UK-BAT)

Hypertension, Resistant to Conventional Therapy | Baroreflex Failure Syndrome

United Kingdom
University of North Carolina, Chapel Hill

Terminated

Postural Changes During Right Heart Catheterization

Pulmonary Hypertension | Right Heart Failure Due to Pulmonary Hypertension

United States
University Hospital Birmingham
British Heart Foundation; Heart of England NHS Trust

Unknown

Energetic Abnormalities in Heart Failure With Preserved Ejection Fraction

Heart Failure, Diastolic

United Kingdom
Baylor Research Institute

Completed

Shear Wave Elastography

Heart Failure | Fibrosis, Liver | Decompensated Heart Failure | Cirrhosis, Liver | Transplant; Failure, Heart

United States
Indiana University
Vanderbilt University

Terminated

Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial (N-FURIOUS)

Heart Failure | Acute Cardiac Failure | Acute Cardiac Pulmonary Edema | Heart Failure Acute

United States
The University of Texas Medical Branch, Galveston

Recruiting

Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation. (A-KHALIFE)

Heart Failure; With Decompensation | Lower Extremity Edema | Heart Failure，Congestive

United States
University Hospital Birmingham NHS Foundation Trust
British Heart Foundation

Completed

Metabolic Manipulation in Chronic Heart Failure

Chronic Heart Failure

United Kingdom
The University of Texas Health Science Center,...
Otto Bock Healthcare Products GmbH

Completed

Clinical Algorithm for Post-Stroke Gait Training With C-Brace

Hemiparesis Due to Stroke | Hemiplegia Due to Stroke

United States
Indiana University
Wayne State University; Vanderbilt University; Case Western Reserve University; Inova Fairfax Hospital

Completed

B-lines Lung Ultrasound Guided ED Management of Acute Heart Failure Pilot Trial (BLUSHED-AHF)

Heart Failure | Acute Cardiac Failure | Acute Cardiac Pulmonary Edema | Heart Failure Acute

United States
University of Texas Southwestern Medical Center

Completed

Early Experience With Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK)

Corneal Edema Secondary to Corneal Endothelial Dystrophy

United States
Gilead Sciences

Terminated

Safety and Efficacy of Simtuzumab (SIM, GS-6624) in Adults With Advanced Liver Fibrosis But Not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH)

Liver Fibrosis Due to NASH

United States, Spain, France, Canada, Germany, Italy, Puerto Rico, United Kingdom, Belgium
Great Ormond Street Hospital for Children NHS Foundation...
Orchard Therapeutics

Completed

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Severe Combined Immunodeficiency Due to ADA Deficiency

United Kingdom
Abbott Medical Devices
Thoratec Europe Ltd

Completed

Screening for Advanced Heart Failure Treatment (SEE-HF) (SEE-HF)

Advanced Heart Failure | CRT and/or ICD

Netherlands, Sweden, Denmark, France, Germany, United Kingdom
Medical University of South Carolina

Completed

Intestinal Function in Neonates With Complex Congenital Heart Disease

Growth Failure | Congenital Heart Defects

United States
University of Calgary
The Centre for the Advancement of Health

Completed

Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure

Hypertension | Edema | Hypotension | Congestive Heart Failure

United States, Canada
Genelex Corporation

Completed

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome P450 CYP2C9 Enzyme Deficiency | Cytochrome P450 CYP2C19 Enzyme Deficiency | Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant | CYP2D6 Polymorphism | Ultrarapid... and other conditions

United States
Nutricia North America
Medical College of Wisconsin; Wake Forest University Health Sciences; Nemours... and other collaborators

Completed

A Study to Evaluate the Effects of a New Formula on the Growth, Safety and Tolerance of Infants With Growth Failure

Congenital Heart Disease | Growth Failure

United States
Glasgow Caledonian University
University of Nottingham; University of Manchester; University of Strathclyde; Edinburgh... and other collaborators

Completed

Helping Ease Anxiety and Depression Following Stroke Stage 3 (HEADS:UP)

Depression | Stroke | Anxiety | Cerebrovascular Accident Due to Cerebral Artery Occlusion

United Kingdom
Fujirebio Diagnostics, Inc.

Completed

Blood Collection From Heart Failure Patients to Evaluate for Galectin-3 Measurement Differences Using Various Collection Tubes

To Measure Galectin-3 in Heart Failure Patients on Commercial Platforms

United States
Wake Forest University Health Sciences
Galderma R&D

Active, not recruiting

Xerosis and Use of Topical Moisturizer

Xerosis Due to Atopic Dermatitis

United States
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; St George's, University of... and other collaborators

Recruiting

Low QRS Voltages in Young Healthy Individuals and Athletes

Dilated Cardiomyopathy | Sudden Cardiac Death | Sudden Cardiac Death Due to Cardiac Arrhythmia | Sudden Cardiac Arrest | Arrhythmogenic Right Ventricular Cardiomyopathy | Arrhythmogenic Left Ventricular Cardiomyopathy

United Kingdom
Albireo

Completed

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases

United Kingdom
ZeaVision, LLC
Sound Retina

Unknown

Prospective Study of Adjunctive Carotenoids Plus Anti-oxidants in Anti-VEGF Treated Diabetic Macular Edema (PROACTIVEDME)

Center-involved Diabetic Macular Edema (CI-DME)

United States
AsclepiX Therapeutics, Inc.

Terminated

Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema (CONGO)

Diabetic Macular Edema (DME)

United States
Joseph Antin
Miltenyi Biomedicine GmbH

No longer available

CliniMACS® CD34+ Reagent System for Expanded Access Use

Graft Failure | Delayed Graft Function | Graft-Versus-Host Disease(GVHD) | Anemia Due to Disturbance of Proliferation and/or Differentiation of Hematopoietic Stem Cells

United States
Virginia Commonwealth University

Terminated

High Dose Vitamin C in Cardiac Surgery Patients

Atrial Fibrillation | Heart Valve Disease | Complications Due to Coronary Artery Bypass Graft | Disorder of Vitamin C

United States
Synvista Therapeutics, Inc

Completed

The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure

Pulmonary Edema | Dyspnea | Heart Failure, Congestive

United States
Novartis Pharmaceuticals

Completed

Comparative Effectiveness of Entresto (Sacubitril/Valsartan) Versus ACEi/ARB in de Novo Heart Failure Patients

de Novo Heart Failure

United States
Mardi Gomberg -Maitland MD, MSc
Ohio State University; Allegheny Singer Research Institute (also known as Allegheny...

Withdrawn

Telemonitoring to Treat Group 2 Pulmonary Hypertension (RECAPTURE)

Pulmonary Hypertension Due to Left Heart Disease

United States
Mayo Clinic
rEVO Biologics

Terminated

Response of Recombinant Antithrombin in Heparin Resistant Patients Undergoing Cardiac Surgery

Thrombophilia Due to Acquired Antithrombin III Deficiency

United States
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Horizon...

Recruiting

Phase I/II Clinical Trial Stem Cell Gene Therapy in RAG1-Deficient SCID (RAG1-SCID)

Severe Combined Immunodeficiency Due to RAG1 Deficiency

Spain, Netherlands, Italy, Poland, Australia, Turkey, United Kingdom
Bijan Najafi, PhD
Orthotic Holdings, Inc.

Completed

OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO

Diabetes | Cancer | Arthritis | Parkinson's Disease | Peripheral Arterial Disease | End Stage Renal Failure on Dialysis | Accidental Falls | Fall Due to Loss of Equilibrium | High Risk of Falls Due to Mobility Limitation

United States
Medical College of Wisconsin
The New York Eye & Ear Infirmary

Completed

Near-infrared Light (NIR) Therapy for Diabetic Macular Edema: A Pilot Study (NIR)

Diabetic Macular Edema

United States
SoniVie Inc.

Active, not recruiting

TReatment of Pulmonary Hypertension Group II Study (TROPHY-II)

Pulmonary Hypertension (PH) Due to Left Heart Disease

United States

Clinical Trials on Edema Due to Heart Failure or Cirrhosis in United Kingdom

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