Clinical Trials on Effect of Drugs

Total 30812 results

The First Affiliated Hospital with Nanjing Medical...

Recruiting

Comparison of Chemoradiotherapy and Chemoradiotherapy Combined With Consolidation Chemotherapy for ESCC

Chemotherapy Effect | Esophageal Squamous Cell Carcinoma | Side Effect of Drug

China
Erasme University Hospital
Hopital Foch

Completed

Fully Automated Anesthesia, Analgesia and Fluid Management

Hemodynamic Instability | Complication of Anesthesia | General Anesthetic Drug Overdose | Adverse Effect of Intravenous Anesthetics, Sequela | Drug Delivery System Malfunction | Underdosing of Other General Anesthetics

Belgium
Technical University of Munich

Completed

Detection of Consciousness by EEG and Auditory Evoked Potentials

Anesthesia | Electroencephalography/ Drug Effect

Germany
University of Aarhus

Completed

Methadone in Cystectomy Patients (METAMORF)

Pathologic Processes | Pain | Pain, Postoperative | Postoperative Complications | Neurologic Manifestations | Bladder Cancer | Neurologic Symptoms | Signs and Symptoms | Side Effect of Drug

Denmark
Yale University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

The Stimulation To Induce Mothers Study (STIM)

Labor Pain | Oxytocin | Induction of Labor Affected Fetus / Newborn | Physiologic Effects of Drugs

United States
Diakonhjemmet Hospital
University of Oslo; Diakonhjemmet Hospital Pharmacy; Diakonhjemmet Foundation

Completed

Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial (EPIMERR)

Drug-Related Side Effects and Adverse Reactions | Drug Interaction Potentiation | Medication Compliance | Remission | Medicinal Substance; Adverse Effect

Norway
Zhejiang Cancer Hospital

Completed

Remifemin Preventing the Climacteric Symptoms in Breast Cancer

Safety Issues | Effect of Drugs

China
National Cheng-Kung University Hospital

Unknown

The Effect and Safety of the Seasonal Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Not on Dialysis

Chronic Kidney Disease | Immunogenicity and Adverse Drug Effect of Vaccines Influenza

Taiwan
Fundación Pública Andaluza para la Investigación...

Not yet recruiting

Proof-of-concept to Evaluate the Efficacy and Safety of Prednisone in Idiosyncratic Hepatotoxicity (DILICORT)

Prednisone | Hepatotoxicity | Idiosyncratic Drug Effect
King Faisal Specialist Hospital & Research Center

Completed

Interaction Between Drug and Placebo Effect:Randomized Placebo Controlled Trials May Not be Accurate in Determining Drug Effect Size

Placebo Effect | Placebo Drug Interaction

Saudi Arabia
Andreas Benesic, MD
MetaHeps GmbH

Unknown

Cells of Monocytic Origin as Surrogate Markers for Individual Drug Effects and Hepatotoxicity

Adverse Reaction to Drug | Drug-induced Disorder of Liver

Hong Kong, Australia, Germany, Japan, Korea, Republic of
University of Zurich
National Center of Cardiology and Internal Medicine named after academician...

Completed

Acclimatization of Healthy Subjects During a Stay at 3200 m

Effects of High Altitude

Kyrgyzstan
BCN Checkpoint
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la... and other collaborators

Recruiting

Harm Reduction Program For Informal PrEP Users In A Community-based Setting (seguiPrEP) (seguiPrEP)

HIV Infections | Sexually Transmitted Diseases | HIV/AIDS | Adherence, Medication | Side Effect of Drug | Vaccination | Preexposure Prophylaxis

Spain
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Massachusetts General Hospital; Guangdong Provincial People's Hospital

Completed

Neoadjuvant Chemotherapy or Chemoradiotherapy in Resectable Oesophageal Carcinoma（NewEC Study）

Chemotherapy Effect | Safety Issues | Radiotherapy Side Effect | Effect of Drugs | Oesophageal Carcinoma

China, United States
Rajesh Deshar

Completed

Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia

Hemodynamic Instability | Effect of Drug | Post-spinal Hypotension | Glycopyrrolate

Nepal
Mansoura University

Recruiting

Effect of Vitamin D Therapy in Autism Spectrum Disorder

Effect of Drug

Egypt
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Fosaprepitant in Patients Receiving Ifosfamide-based Regimen

Sarcoma | Chemotherapy-induced Nausea and Vomiting | Effects of Chemotherapy | Adverse Effects of Medical Drugs

United States
Yale University

Completed

Neuroimmune Effects of Opioid Administration (NOA)

Drug Effect

United States
King Faisal Specialist Hospital & Research Center

Completed

The Placebo Effect May Involve Modulating Drug Bioavailability

Pharmacokinetics | Placebo Effect | Drug Half Life

Saudi Arabia
Renaissance RX
Syntactx

Unknown

Diagnosing Adverse Drug Reactions Registry (DART)

Genetics of Drug Metabolism

United States
Guangdong Women and Children Hospital

Completed

Safety of Autologous Cord Blood Cells for Preterm Infants.

Safety Issues | Neonatal Death | Effect of Drugs
Guangdong Women and Children Hospital

Unknown

Safety and Efficacy of Autologous Umbilical Cord Blood Mononuclear Cells Transfusion in Neonates

Safety Issues | Neonatal Death | Effect of Drugs

China
Uzoma Chinyei Joan

Recruiting

Comparison of Preserved and Preservative-free Latanoprost 0.005% in Primary Open Angle Glaucoma and Ocular Hypertensive Patients, at Guinness Eye Centre, Lagos.

Effect of Drug

Nigeria
National Institute on Aging (NIA)

Completed

Sodium-glucose Co Transporter 2 (sGLT2) Inhibitor and Endogenous Ketone Production

Physiological Effects of Drugs | Hypoglycemic Agents | Empaglifozin | Sodium-Glucose Transporter 2 Inhibitors

United States
Beijing Anzhen Hospital

Unknown

the Effect Between Platelet Reactivation and Antiplatelet Drugs

Drug Effect Disorder | Platelet Procoagulant Activity Deficiency

China
Washington University School of Medicine

Completed

Efavirenz and Ritonavir on Human Brain P-Glycoprotein

Drug Effects

United States
Luye Pharma Group Ltd.

Completed

Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Schizophrenia Spectrum and Other Psychotic Disorders | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Neurotransmitter Agents | Central...

United States
Pi Research Consultancy Center, Bangladesh

Not yet recruiting

Role of Tofacitinib in Vitiligo Patients (ETV)

Vitiligo | Effect of Drug
Ethem Unal, M.D., PhD, Associate Prof of Surgery...

Unknown

The Efficacy of Nifedipine in the Management of Preterm Labor (BOG/TH/PTL)

Preterm Birth | Preterm Labor | Preterm Labor Without Delivery | Side Effect of Drug | Preterm Labor With Preterm Delivery in Third Trimester | Calcium-Channel Blockers Toxicity
Zhejiang University

Completed

Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer

Quality of Life | Complications | Adverse Drug Event | Length of Stay | Hospital Costs

China
Peking Union Medical College Hospital
Beijing Bethune public welfare fund

Terminated

Effects of Conbercept in Refractory Uveitic Macular Edema and VEGF

Uveitis | Macular Edema | Vascular Endothelial Growth Factor | Effect of Drugs

China
SMG-SNU Boramae Medical Center

Unknown

Effect of Sedatives on Perioperative Electroencephalogram in Elderly Patients Undergoing Spinal Anesthesia

Effect of Sedatives
Radiotherapie

Completed

Trial of SBRT With Concurrent Ipilimumab in Metastatic Melanoma

Melanoma | Effects of Immunotherapy | Adverse Effect of Radiation Therapy

Belgium
Donders Centre for Cognitive Neuroimaging
Dr. Hanneke den Ouden, Donders Centre for Cognition, Radboud University; Dr... and other collaborators

Completed

Dopamine and Cognition

Sulpiride's Effect on Striatal BOLD Signal During Working Memory Gating | Interaction of Sulpiride, Average Reward Rate and Evidence Accumulation | Interaction of Sulpiride, Average Reward Rate and Cognitive Effort

Netherlands
Taipei Medical University
Shin Kong Wu Ho-Su Memorial Hospital

Enrolling by invitation

Effects of Knee Injections on Patients With Knee Osteoarthritis

Knee Osteoarthritis | Injection | Effect of Drug

Taiwan
The Young Investigator Group of Cardiovascular...

Completed

The Effects of Sacubitril/Valsartan on the Heart Functions

Drug Effect
Hasselt University
Jessa Hospital

Unknown

Measuring the Incidence of Hospital Readmissions Based on Adverse Drug Events

Incidence of Readmissions | ADE's Due to Anticoagulants

Belgium
Richmond Pharmacology Limited

Completed

Food and Insulin Effect on QT/QTC Interval of ECG (C11035)

Effects of Different Meals on the QT/QTc Interval | Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use | C-Peptide Effects on the QT/QTc Interval | Moxifloxacin ECG Profile in Fed and Fasted State | Japanese vs. Caucasian TQT Comparison

United Kingdom
Technical University of Munich

Completed

Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers

Anesthesia | Drug Effects

Germany
Bournemouth University
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust

Completed

Bournemouth University Resilience Training for Surgeons (BURTS)

Effect of Training

United Kingdom
Wockhardt

Completed

Phase I, Open Label,Crossover Food-Effect and Absolute Bioavailability Study of WCK2349 and WCK771 in Healthy Adult Human Volunteers

Effect of Food

United States
Fudan University

Recruiting

Efficacy and Safety of Pyrotinib in HER2 Positive Gastrointestinal Tumors

Effect of Drug | Gastrointestinal Tumor

China
Taisho Pharmaceutical Co., Ltd.

Completed

A Food Effect Study of TS-142 in Healthy Subjects

Effect of Food

Japan
National Cancer Institute, Egypt

Recruiting

Comparison of Duloxetine Versus Pregabalin

Drug Effect

Egypt
Guangdong Women and Children Hospital

Unknown

Clinical Effect and Safety of Autologous Umbilical Cord Blood Transfusion in the Treatment of Cerebral Palsy

Safety Issues | Effect of Drugs

China
Chulalongkorn University
Mahidol University

Completed

Quality of Life of Patients With a History of Drug Allergy in Thailand

Quality of Life

Thailand
Luye Pharma Group Ltd.

Completed

Relative Bioavailability of LY03010 Compared to Listed Drug

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Central Nervous System Depressants | Neurotransmitter Agents | Schizophrenia Spectrum

United States
Athens General Children's Hospital "Pan. & Aglaia...

Completed

Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children

Effect of Anesthesia in Postoperative Pain | Effect of Anesthesia in Extubation Time | Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit | Effect of Anesthesia in Postoperative Adverse Events | Effect of Anesthesia in Discharge Time From the Hospital

Greece
Peking University People's Hospital
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib With Ifosfamide Plus Etoposide for Relapsed or Refractory Osteosarcoma (OAIE) (OAIE)

Toxicity | Effect of Drug | Drug

China
University of Reading
Unilever R&D

Not yet recruiting

Can the Reduction of Iron Availability Caused by Tea Consumption Change the Gut Microbiota Composition and Disrupt Host Body-iron Status

Focus of Study: 1- Effect of Tea Consumption on Gut Microbiota | Focus of Study: 2- Effect of Tea Consumption on Body-iron Status

United Kingdom

Clinical Trials on Effect of Drugs

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