Clinical Trials on Efficacy and Safety

Total 413310 results

Latin American Cooperative Oncology Group
AstraZeneca

Not yet recruiting

A Real-World Assessment of the Demographic, Clinical Characteristics and Outcomes of a Brazilian Cohort of Previously Untreated Extensive Stage-Small Cell Lung Cancer Receiving Durvalumab Combined With Platinum-Etoposide in (ES-SCLC) in Brazil (EDUR-BRA)

Extensive-stage Small-cell Lung Cancer

Brazil
Huazhong University of Science and Technology

Recruiting

Zanubrutinib Combined With R-CHOP in the Treatment of Newly Diagnosed DLBCL With p53 Protein Expression

Diffuse Large B Cell Lymphoma

China
Jinming Yu

Recruiting

Real-World Study of Iruplinalkib in the Treatment of ALK-Positive Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer (NSCLC)

China
Hunan Province Tumor Hospital

Recruiting

Real-World Study on the Efficacy of IBI-322 in Combination With Lenvatinib for the Treatment of Extensive Stage Small Cell Lung Cancer

Extensive-stage Small-cell Lung Cancer

China
Centre Hospitalier Universitaire Dijon

Not yet recruiting

Pilot Study of the Contribution of Fractional Exhaled Nitric Oxide as a Prognostic Marker of Response to Anti-PD-L1 Immunotherapy in Non-small Cell Lung Cancer (FENOTYPE)

Metastatic Non-small Cell Lung Cancer

France
Second Xiangya Hospital of Central South University
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

Propranolol Hydrochloride in Combination With Sintilimab and Platinum-based Chemotherapy for Treatment of Advanced Non-small Cell Lung Cancer (BRIO)

Non Small Cell Lung Cancer | Propranolol
Liling Zhang
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Prospective, Single Arm, Single Center Study of Duvelisib Combined With Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma (PTCL)

Newly Diagnosed Peripheral T-cell Lymphoma

China
Taiho Oncology, Inc.

Recruiting

REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors) (REZILIENT3)

Advanced or Metastatic NSCLS With Exon 20 Insertion Mutation

United States, Spain, Canada, Italy, Israel, Japan, United Kingdom, Korea, Republic of, Germany, France, Turkey, Belgium, Netherlands, Philippines, Poland, Singapore
Wroclaw Medical University

Not yet recruiting

The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin

Muscle Pain | Myalgia | Headache | Orofacial Pain | Headache, Tension | Headaches Muscular

Poland
AstraZeneca
Hospital Israelita Albert Einstein

Recruiting

Brazilian Reality in the Diagnosis and Treatment of Diffuse Large B Cell Lymphoma - BRA-DLBCL

Diffuse Large B Cell Lymphoma

Brazil
Peng Liu

Recruiting

Prospective Clinical Study of ZPR Regimen in Elderly Treatment-naive Diffuse Large B-cell Lymphoma

Diffuse Large B Cell Lymphoma

China
Liaoning Tumor Hospital & Institute

Not yet recruiting

Zanubrutinib Combined With R-CHOP Regimen in the Treatment of Newly Diagnosed DLBCL With High-risk Factors

Diffuse Large B Cell Lymphoma

China
Zhao Weili

Not yet recruiting

A Real-world Study of Tafasitamab in Combination With Lenalidomide in Patients withR/R DLBCL

Diffuse Large B-cell Lymphoma

China
Ruijin Hospital

Recruiting

A Combination Study of CAR-T Therapy in r/r B-NHL

Diffuse Large B Cell Lymphoma

China
Ain Shams University

Recruiting

Effect of Losartan on the Incidence and Severity of Chemotherapy-Induced Mucositis in Gastrointestinal Cancer Patients

Colorectal Cancer | Chemotherapy | Oral Mucositis | Intestinal Mucositis

Egypt
SignalChem Lifesciences Corporation
Merck Sharp & Dohme LLC

Recruiting

Testing Experimental Anti-cancer Drug SLC-391 With an Approved Immunotherapy Drug, Pembrolizumab, for Advanced Lung Cancers

Lung Cancer Metastatic | Lung Cancer, Nonsmall Cell | Lung Cancer Stage IV

United States, Canada
Jianzhen Shan, MD

Recruiting

In Vitro Organoid Drug Sensitivity-Guided Treatment for Metastatic Pancreatic and Gastric Cancer (ODYSSEY)

Gastric Cancer | Pancreatic Cancer

China
University of Cologne
Charite University, Berlin, Germany; University Hospital, Essen; University Medicine... and other collaborators

Recruiting

Improvement of Personalized Lung Cancer Care Through Digital Connection and Patient Participation (DigiNet) (DigiNet)

Non-small Cell Lung Cancer Stage IV

Germany
The First Affiliated Hospital of Soochow University

Recruiting

Pro-miniCHOP-like Regimen for Treatment-naive Elderly Patients

Diffuse Large B Cell Lymphoma

China
University Hospital, Montpellier

Not yet recruiting

Liver Cancer and Immunotherapy in the Liquid Biopsy Era (LILIPSY)

Hepatocellular Carcinoma | Liquid Biopsy | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Immune Checkpoint Inhibitor
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

R-MINE+X in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-cell Lymphoma
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

R-CMOP in Patients With Primary Diffuse Large B-cell Lymphoma

Diffuse Large B-cell Lymphoma
Activ Surgical

Recruiting

Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic Cholecystectomy

Cholecystitis | Biliary Dyskinesia | Cholelithiasis

United States
Pingping Song

Not yet recruiting

Neoadjuvant WX-0593 in Resectable ALK-positive or ROS1-positive Non-small Cell Lung Cancer

Non-Small Cell Lung Cancer(NSCLC)

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Clinical Study of Anti-CD1a CAR-T in the Treatment of R/R Acute T-lymphoblastic Leukemia/Lymphoblastic Lymphoma

Acute T-lymphoblastic Leukemia | Acute T-lymphoblastic Lymphoma

China
University of Bologna
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Associazione Italiana per...

Recruiting

Role of the Gut Microbiome in the Outcome of Diffuse Large B-Cell Lymphoma Patients Treated With CAR-T Cell Therapy (MicroCar)

Diffuse Large B Cell Lymphoma

Italy
Mayo Clinic

Recruiting

CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Centre Henri Becquerel

Not yet recruiting

Real-Time Monitoring of Circulating Tumor DNA and Study of Prognostic Factors in Patients Treated With CAR-T Cells (RT-CAR)

Diffuse Large B Cell Lymphoma

France
AbelZeta, Inc.
Nektar Therapeutics

Recruiting

C-TIL051 in Non-Small Cell Lung Cancer

Metastatic Non Small Cell Lung Cancer

United States
Arcus Biosciences, Inc.
Gilead Sciences

Recruiting

Study With Immunotherapy Combinations in Participants With Metastatic Non-Small Cell Lung Cancer (EDGE-Lung)

Advanced Non-Small Cell Lung Cancer

United States, Korea, Republic of, Australia, United Kingdom, Taiwan, Spain
Chang Gung Memorial Hospital

Not yet recruiting

Sarcopenia and Multimodal Rehabilitation on the Prognosis of Rectal Cancer Patients Receiving CCRT

Rectal Cancer

Taiwan
ADC Therapeutics S.A.

Recruiting

A Study to Evaluate the Pharmacokinetics and Safety of Loncastuximab Tesirine in Participants With Relapsed or Refractory Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma With Hepatic Impairment (LOTIS-10)

Diffuse Large B-Cell Lymphoma | High-grade B-cell Lymphoma

Taiwan, Korea, Republic of, United States, Brazil
British Columbia Cancer Agency

Recruiting

177Lu-HTK03170 in mCRPC With PSMA Positive Disease

Prostate Cancer Metastatic | Metastatic Castration-resistant Prostate Cancer | Castrate Resistant Prostate Cancer

Canada
Fondazione Ricerca Traslazionale

Recruiting

Randomized Trial Comparing Standard of Care Versus Immune- Based Combination in Relapsed Stage III Non-small-cell Lung Cancer (NSCLC) Pretreated With Chemoradiotherapy and Durvalumab

Non-small-cell Lung Cancer Patients

Italy
Ruijin Hospital

Recruiting

Sequential Chemo-immunotherapy Plus Thoracic Radiotherapy for Elderly and/or Frail Stage III Non-small-cell Lung Cancer

Non-small Cell Lung Cancer Stage III

China
Daiichi Sankyo
Merck Sharp & Dohme LLC; AstraZeneca

Recruiting

Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

Metastatic Non Small Cell Lung Cancer

Belgium, Australia, United States, Korea, Republic of, Spain, China, France, Germany, Thailand, Brazil, Japan, Hong Kong, Austria, Greece, Switzerland, Netherlands, Romania, Hungary, Italy, Chile, Taiwan, Poland, Canada, Argentina, Turkey
M.D. Anderson Cancer Center
Loxo Oncology

Recruiting

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

Mantle Cell Lymphoma | Non Hodgkin Lymphoma | Hematologic Malignancy

United States
Sierra Neurovision
CEISO; Institut des Sciences de la Vision

Not yet recruiting

Performance and Safety Evaluation of the S360 Medical Device Software. (ArgoS360)

Binocular Vision Disorder | Binocular Eye Movement Disorder | Ocular Motion; Disorder

France
Jiesi Yingda Pharmaceutical Technology (Suzhou)...

Recruiting

VIC-1911 Combined With Osimertinib for EGFR -Mutant Non-small Cell Lung Cancer (VIC-1911)

Advanced Non-small Cell Lung Cancer

China
Stephan Grupp MD PhD
Children's Hospital of Philadelphia

Recruiting

Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

B Cell Acute Lymphoblastic Leukemia (B-ALL) | B Lineage Lymphoblastic Lymphoma

United States
Sichuan Cancer Hospital and Research Institute

Recruiting

Camrelizumab Combination With SBRT and Concurrent Chemotherapy Treated Stage IV Oligometastatic Non-small Cell Lung Cancer (IMCORT-2)

Non-small Cell Lung Cancer Metastatic

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; Mirati Therapeutics Inc.

Recruiting

Neoadjuvant KRAS G12C Directed Therapy With Adagrasib (MRTX849) With or Without Nivolumab (Neo-Kan)

Resectable Non-Small Cell Lung Cancer

United States
Sun Yat-sen University

Recruiting

Study of Tislelizumab for Locally Advanced Non-Small Cell Lung Cancer Following Neoadjuvant Chemotherapy Plus Tislelizumab ± Bevacizumab and Definitive Concurrent Chemoradiation Therapy

Stage III Non-small Cell Lung Cancer

China
Peking Union Medical College

Recruiting

Correlation Between Efficacy of Osimertinib and EGFR T790M Status and Ratio Via ddPCR in NSCLC

Non-small Cell Lung Cancer | EGFR T790M | Osimertinib | ddPCR

China
The First Affiliated Hospital of Nanchang University
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical... and other collaborators

Recruiting

Effect and Long-Term Outcomes of Indocyanine Green Fluorescence Imaging Method Versus Modified Inflation-Deflation Method in Identification of Intersegmental Plane（IMPLANE-0529） (IMPLANE-0529)

Segmentectomy | Non-small Cell Lung Cancer Stage I

China
Incyte Corporation

Recruiting

Study to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (firmMIND) (firmMIND)

Diffuse Large B-Cell Lymphoma | Large B-Cell Lymphoma

Croatia, Serbia, Czechia, Finland, Israel, Romania, Denmark, Hungary, Ireland, Poland, Turkey, Bulgaria, Norway, United Kingdom
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Phase Ib/II Study of SHR-8068 Injection in the Treatment of Advanced Non-small Cell Lung Cancer

Advanced Non-small Cell Lung Cancer

China
Fudan University

Not yet recruiting

Bevacizumab Plus Nab-paclitaxel and Platinum for Immunotherapy-treated Non-squamous Non-small Cell Lung Cancer (BETTER)

Non-small Cell Lung Cancer Metastatic
Biogen

Recruiting

A Study to Learn About the Safety of BIIB080 and Whether it Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age (CELIA)

Mild Cognitive Impairment Due to Alzheimer's Disease | Alzheimer's Disease Dementia

Belgium, United States, Australia, Italy, Spain, Denmark, United Kingdom, Czechia, France, Poland, Switzerland, Germany, Canada, Japan, Finland, Netherlands, Sweden
Fundación GECP

Recruiting

Study of Pembrolizumab, Lenvatinib and Chemotherapy Combination in First Line Extensive-stage Small Cell Lung Cancer (PEERS)

Small Cell Lung Cancer Extensive Stage

Spain

Clinical Trials on Efficacy and Safety

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