Clinical Trials on Efficacy and Safety

Total 415918 results

Gilead Sciences

Completed

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 or 4 HCV and HIV-1 Co-infection

HIV | Hepatitis C Virus

United States, New Zealand, Canada, Puerto Rico
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Immunex Corporation

Withdrawn

Therapy of Relapsed AML With Chemotherapy and Dendritic Cell Activated Lymphocytes

Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia
Mingzhi Zhang

Unknown

Crizotinib Combined With Etoposide Capsule Followed by Auto-HSCT for Relapsed and Refractory ALK+ ALCL

ALK-Positive Anaplastic Large Cell Lymphoma

China
ShuGuang Hospital
Beijing YouAn Hospital; Beijing Ditan Hospital; Shanghai Zhongshan Hospital; Tongji... and other collaborators

Unknown

Traditional Chinese Medicine Combined With Entecavir to Treat Refractory Liver Fibrosis in Liver Cirrhosis Due to HBV

Hepatitis B Virus Related Cirrhosis

China
Ethicon Endo-Surgery

Completed

Powered Vascular Stapler in Video-Assisted Thoracoscopic (VAT) Lobectomies

Non Small Cell Lung Cancer

United States
Hospices Civils de Lyon

Completed

HBV Virions Bound Proteins

Hepatitis B Virus Infection

France
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Boceprevir/Peginterferon Alfa-2a/Ribavirin in Interleukin-28B CC Allele-Positive Chronic Hepatitis C Virus (HCV) Genotype 1 Participants (P07755)

Hepatitis C, Chronic
Generic Devices Consulting, Inc.
Biocompatibles UK Ltd

Terminated

Chemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal Cancer (PARAGON)

Unresectable Metastatic Colo-rectal Cancer

United States
Hunter Holmes Mcguire Veteran Affairs Medical Center
VA Mental Illness Research, Education and Clinical Centers

Completed

Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting

Cannabis Dependence | Opioid-use Disorder | Cocaine Use Disorder | Cocaine Dependence | Opiate Dependence

United States
GlaxoSmithKline

Completed

Long-term Persistence of Immunity Against Hepatitis B in 7-8 Years Old Children After Hepatitis B Vaccination.

Hepatitis B Vaccine

Germany
First Affiliated Hospital Xi'an Jiaotong University

Unknown

PTED Versus Radiofrequency Ablation for Lumbar Disc Herniation (PTED)

Lumbar Disc Herniation | Chronic Low Back Pain

China
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Gemcitabine Plus Radiation Therapy or Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer

Lung Cancer

United States
M.D. Anderson Cancer Center
Janssen Scientific Affairs, LLC

Withdrawn

Trial Evaluating the Efficacy and Safety of Daratumumab in Subjects With Relapsed/Refractory B-cell or T-cell Precursor Acute Lymphoblastic Leukemia (ALL)

Malignant Neoplasms Stated as Primary Lymphoid Haematopoietic
Sandoz
Novartis Pharmaceuticals

Completed

GP2013 in Japanese Patients With CD20 Positive Low Tumor Burden Indolent B-cell Non-Hodgkin's Lymphoma

Indolent B-cell Non-Hodgkin's Lymphoma

Japan
University of Dublin, Trinity College

Unknown

The IMPETUS Cancer Trial. A Technology Delivered Physical Activity Intervention in Cancer (IMPETUS)

Cancer, Breast | Malignancy | Cancer, Colorectal

Ireland
EMD Serono
Pfizer

Completed

Rebif® Versus Copaxone® in the Treatment of Relapsing Remitting Multiple Sclerosis

Relapsing-remitting Multiple Sclerosis

United States, United Kingdom, Argentina, Austria, Brazil, France, Germany, Italy, Netherlands, Russian Federation, Spain, Switzerland
Institut National de la Santé Et de la Recherche...
Institut Bergonié; Plateforme labellisée Inca - Institut Bergonié, Bordeaux; Plateforme... and other collaborators

Completed

Molecular Profiling to Improve Outcome of Patients in Cancer. A Pilot Study (MULTIPLI-0)

Soft Tissue Sarcoma | Colorectal Carcinoma

France
Tata Memorial Centre

Terminated

Correlation Between Intraocular Pressure Measurement by Tomometer and Anterior Chamber Depth Measurement by Ultrasound

Gastrointestinal Cancer | Malignant Female Reproductive System Neoplasm | Urological Cancer

India
The University of Hong Kong
Taiho Pharmaceutical Co., Ltd.

Completed

Intraperitoneal Docetaxel With Cisplatin and TS-ONE for Gastric Cancer With Peritoneal Carcinomatosis

Gastric Cancer | Peritoneal Carcinomatosis

China
Heidelberg University

Completed

Imatinib Mesylate With or Without Interferon Alfa or Cytarabine Compared With Interferon Alfa Followed by Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

Leukemia

Germany, Switzerland
SciClone Pharmaceuticals International (Cayman)...
Parexel; National Cheng-Kung University Hospital

Unknown

An Open-Label Phase I/II Clinical Study of PT-112 in Combination With Docetaxel in Subjects With Advanced Solid Tumor in a Phase I Dose Escalation Study and in Subjects With Non-Small Cell Lung Cancer (NSCLC) in a Phase II Dose Confirmation Study

Non-Small Cell Lung Cancer | Advanced Solid Tumor

Taiwan
Genentech, Inc.

Completed

A Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously Untreated Advanced Diffuse Large B-Cell Lymphoma (GATHER)

Lymphoma, B-Cell

United States
Hanmi Pharmaceutical Company Limited

Completed

Phase I/II Trial to Evaluate Safety, Tolerability and Pharmacokinetic Profile of HM61713 in NSCLC Patients

Non Small Cell Lung Cancer

Korea, Republic of
University of Florida
Vertex Pharmaceuticals Incorporated

Completed

Open-Label Safety Study of Telaprevir and Sofosbuvir in Chronic Hepatitis C Genotype 1 (STEADFAST)

Hepatitis C, Chronic

United States
Asociacion para el Estudio del Higado
Merck Sharp & Dohme LLC

Unknown

Chronic Hepatitis C in Chronic Hemodialysis Recipients - An Observational Study ((CHINCHERO))

HCV Infection
Hoffmann-La Roche

Completed

An Observational Study of Pegasys in Dual- or Triple-Therapy in Patients With Chronic Hepatitis C

Hepatitis C, Chronic

Germany
Wen-hong Zhang

Unknown

Efficacy and Safety of Combination Therapy of Thymalfasin and Entecavir in HBeAg-positive ETV-experienced Patients

Chronic Hepatitis b

China
Khondrion BV
Radboud University Medical Center

Completed

The KHENERGY Study (KHENERGY)

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS | Mitochondrial Encephalomyopathies | MIDD

Netherlands
Kanazawa University

Unknown

Phase I of Vorinostat-Iressa Combined Therapy on Resistance by BIM Polymorphysim in EGFR Mutant Lung Cancer (VICTORY-J)

Non-Small-Cell Lung Carcinoma

Japan
Neuren Pharmaceuticals Limited

Terminated

A Safety and Efficacy Study of NNZ-2566 in Patients With Mild Traumatic Brain Injury (mTBI)

Concussion

United States
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University

Terminated

Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation

Rectal Cancer | for Bowel Dysfunction Following Surgery for Rectal Cancers

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Followed by Radiation Therapy and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery

Lung Cancer

United States
Chinese PLA General Hospital

Unknown

A Feasibility and Safety Study of Universal Dual Specificity CD19 and CD20 or CD22 CAR-T Cell Immunotherapy for Relapsed or Refractory Leukemia and Lymphoma

B Cell Lymphoma | B Cell Leukemia

China
CHU de Reims

Completed

Feasibility of Systematic Handgrip Strength (HGS) Testing and Short-term Changes in Muscle Strength in Digestive Cancer Patients Treated by Chemotherapy (FIGHTDIGO)

Chemotherapy | Sarcopenia | Muscle Strength | Digestive Cancer | Handgrip Strength Test
ImmunoGen, Inc.

Completed

IMGN529 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia

Lymphoma, Non-Hodgkin | Chronic Lymphocytic Leukemia

United States, Switzerland
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy Combined With Paclitaxel and Carboplatin in Treating Patients With Stage III Non-Small Cell Lung Cancer

Lung Cancer

United States, Canada
AbbVie

Completed

A Study to Assess the Effect of Rifampin on the Metabolism of Navitoclax

Solid Tumors | Lymphoma, Including Chronic Lymphocytic Leukemia
Hoffmann-La Roche

Completed

An Observational Study of MabThera/Rituxan (Rituximab) Plus Chemotherapy As First-Line Treatment in Patients With Diffuse Large B-Cell Lymphoma or Follicular Lymphoma

Diffuse Large B-Cell Lymphoma

China
Alios Biopharma Inc.
Janssen Pharmaceutica

Terminated

First in Human Study of AL-704; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C

Chronic Hepatitits C

Georgia, Moldova, Republic of, France
Teva Pharmaceuticals Europe

Completed

Study in Patients' With Persistent Asthma and Chronic Obstructive Pulmonary Disease (SPRINT)

Chronic Obstructive Pulmonary Disease | Asthma

Croatia, Denmark, Ireland, Italy, Netherlands, Norway, Portugal, Spain, Sweden, United Kingdom
Clinica Universidad de Navarra, Universidad de...
Spanish National Health System

Unknown

Rituximab and Autologous Effector Lymphocytes in Non-Hodgkin Follicular Lymphoma in Response to First Line Chemotherapy

Follicular Lymphoma | Follicular Non-Hodgkin´s Lymphoma | Autologous Effector Lymphocytes

Spain
Oregon Health and Science University
National Center for Research Resources (NCRR)

Completed

Quantification of Balance in Acutely Concussed Athletes

Mild Traumatic Brain Injury | Concussion | mTBI

United States
National Institute of Allergy and Infectious Diseases...

Completed

Leukapheresis for Research on HCV-Coinfected Patients

HIV Infections | Hepatitis C

United States
Hoffmann-La Roche

Completed

A Study of Extended Therapy of PEGASYS (Peginterferon Alfa-2a) in Combination With COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C and Slow Response

Hepatitis C, Chronic

Israel
Uijeongbu St. Mary Hospital
Daewoong Pharmaceutical Co. LTD.

Unknown

A Clinical Trials to Evaluate the Efficacy and Safety of Tenofovir With and Without DWPUR001 in Patients With HBV

Hepatitis; Virus, Chronic, Type B

Korea, Republic of
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

High-Dose Immunosuppression and Autologous Transplantation for Multiple Sclerosis (HALT MS) Study

Relapsing-Remitting Multiple Sclerosis

United States
Shandong Provincial Hospital

Unknown

Microwave Plus Chemotherapy Versus Chemotherapy for Advanced NSCLC

Non Small Cell Lung Cancer

China
Stanford University

Completed

Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients

Moyamoya Disease | Cerebrovascular Accident

United States
Gruppo Italiano Terapie Innovative nei Linfomi

Completed

Comparison of HD Chemotherapy Followed by Auto-transplant and R-CHOP in High Risk Patients With DLBCL.

Diffuse Large B-Cell Lymphoma

Italy
Assiut University

Unknown

Assessment of Patients With Hepatitis C Virus Related Liver Cirrhosis After Sustained Response to Direct Acting Anti Viral Drugs.

Liver Cirrhosis | Hepatitis C

Egypt

Clinical Trials on Efficacy and Safety

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