Clinical Trials on Epilepsy, Tonic-Clonic

Total 34573 results

Biomedizinische Forschungs gmbH
Medical University of Vienna

Completed

Clinical Trial of the BioMed rTSST-1 Variant Vaccine in Healthy Adults

Toxic Shock Syndrome

Austria
Oslo University Hospital

Completed

Epilepsy Surgery and Cognitive Outcome

Epilepsy, Temporal Lobe

Norway
Indiana University
Greenwich Biosciences; Child Neurology Foundation

Completed

Improving Patient Communication About SUDEP

Epilepsy | SUDEP

United States
SK Life Science, Inc.

Completed

An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures.

Epilepsy | Epilepsies, Partial | Epilepsy, Complex Partial | Complex Partial Seizures
Stanford University
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Transcranial Magnetic Stimulation for BECTS (TMS4BECTS)

Learning Disorders | Benign Epilepsy With Centrotemporal Spikes | Language Problems

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
Lancashire Teaching Hospitals NHS Foundation Trust

Recruiting

Neurofrailty: A Study of Late-onset Epilepsy and Its Associations

Stroke | Dementia | Late Onset Epilepsy

United Kingdom
UCB BIOSCIENCES, Inc.

Completed

Study to Assess the Long-term Safety of Oral Lacosamide in Subjects With Partial-onset Seizures

Partial Epilepsies | Partial Onset Seizures

United States
Joseph Cravero

Completed

A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging

Epilepsy | Cerebral Palsy | Developmental Delay

United States
Universitair Ziekenhuis Brussel

Active, not recruiting

An Assessment of the Occurrence of Hypothyroidism in Patients Treated With RAI for Hyperthyroidism.

Nodule Solitary Thyroid | Toxic Multinodular Goiter | Radioactive Iodine-Induced Hypothyroidism

Belgium
Assistance Publique - Hôpitaux de Paris
OSO-AI

Recruiting

Characterization by Automated System on Infantile Spasmes (REASSESS)

Infantile Spasm

France
UCB BIOSCIENCES, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome (ORCHID)

Dravet Syndrome

United States, Belgium, Germany, Italy, United Kingdom
Cook Children's Health Care System
Encoded Therapeutics

Recruiting

GABA Biomarkers in Dravet Syndrome

Dravet Syndrome

United States
Hospices Civils de Lyon

Recruiting

Neurodevelopmental Impact of Epilepsy on Autonomic Function in Dravet Syndrome (AUTONOMIC)

Epilepsy | Dravet Syndrome

Belgium, France, Germany
Stoke Therapeutics, Inc

Enrolling by invitation

An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome

Dravet Syndrome

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Neuronal Excitability of HCN1 Channel Mutations in Dravet Syndrome (EXCIDRAH)

Dravet Syndrome

France
Jazz Pharmaceuticals

Completed

Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

France, United States, United Kingdom, Poland
INSYS Therapeutics Inc

Withdrawn

Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Participants With Inadequately Controlled Dravet Syndrome

Dravet Syndrome
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Boston Children's Hospital
Encoded Therapeutics

Recruiting

Transcranial Magnetic Stimulation to Measure Cortical Excitability in Dravet Syndrome

Dravet Syndrome

United States
Stoke Therapeutics, Inc

Completed

An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome

Dravet Syndrome

United States
Fondazione Policlinico Universitario Agostino Gemelli...
IRCCS San Raffaele

Enrolling by invitation

EXploring novEl Molecular Determinants of DRAvet Syndrome Phenotype Heterogeneity (EXEDRA)

Dravet Syndrome

Italy
Zogenix International Limited, Inc., a subsidiary...

Completed

An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome

Dravet Syndrome

United States, United Kingdom, Spain, Belgium, Italy, Australia, Denmark, Germany, Canada, Japan, Netherlands, France
Gillette Children's Specialty Healthcare
Mayo Clinic; Dartmouth-Hitchcock Medical Center; Ann & Robert H Lurie Children...

Completed

Verapamil as Therapy for Children and Young Adults With Dravet Syndrome

Dravet Syndrome

United States
University of California, Los Angeles

Available

Treatment of Dravet Syndrome With Fenfluramine (Expanded Access Protocol) (Dravet)

Dravet Syndrome

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Creatine Deficiency Syndromes (BioCDS) (BioCDS)

Intellectual Disability | Developmental Delay | Intractable Epilepsy | Movement Disorder | Behavioral Disorder

India, Sri Lanka, Egypt
Xijing Hospital

Enrolling by invitation

The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients

Epileptic Seizures Related to Drugs

China
Second Affiliated Hospital, School of Medicine,...

Completed

Association of Processing Speed Dysfunction and Brain Functional Abnormality in ECTS

Epilepsy, Rolandic

China
National Institute of Neurological Disorders and...

Completed

MRI in Autosomal Dominant Partial Epilepsy With Auditory Features

Epilepsies, Partial

United States
University Hospital, Bordeaux
Institut National de la Santé Et de la Recherche Médicale, France; Centre National...

Recruiting

Electroclinical Correlation of Anxiety (IRAnxNet)

Generalized Anxiety Disorder | Drug Resistant Epilepsy | Anxiety Disorder

France
University of Iowa

Recruiting

Carbon Dioxide (CO2) Chemosensitivity and SUDEP

Epilepsy | SUDEP

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients

Epilepsy | Epilepsy, Generalized | Seizures | Epilepsies, Partial
Hospices Civils de Lyon

Completed

Efficacy of IntraVenous ImmunoGlobulins in Toxic Shock Syndromes: a Paediatric Pilot Study (IVIG)

Toxic Shock Syndrome

France
IRCCS San Raffaele

Not yet recruiting

Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy

Epilepsy | Focal Epilepsy

Italy
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Dravet Syndrome

Australia
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome (ENDEAVOR)

Dravet Syndrome

United States
Epygenix
Forest Hills Lab; Liberyx Therapeutics

Recruiting

EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome (ARGUS)

Dravet Syndrome

United States, Canada, Spain, Georgia, Hungary
Zogenix, Inc.

Approved for marketing

ZX008 Expanded Access Protocol

Dravet Syndrome
Zogenix International Limited, Inc., a subsidiary...

Completed

A 2-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children ≥ 2 Years Old and Young Adults With Dravet Syndrome

Dravet Syndrome

United States, France, United Kingdom, Canada, Germany, Netherlands, Spain
Jazz Pharmaceuticals

Completed

A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

United States, United Kingdom
Jazz Pharmaceuticals

Completed

GWPCARE2 A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet Syndrome

Epilepsy | Dravet Syndrome

United States, Spain, Israel, Poland, Australia, Netherlands
University of Colorado, Denver

No longer available

Compassionate Use of Stiripentol in Dravet Syndrome

Dravet Syndrome

United States
Children's Hospital Medical Center, Cincinnati

Approved for marketing

Treatment Plan to Provide Expanded Access to Stiripentol for Patients With Dravet Syndrome

Dravet Syndrome

United States
H. Lundbeck A/S

Terminated

Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

Dravet Syndrome

United States, Mexico
H. Lundbeck A/S

Withdrawn

Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

Dravet Syndrome

United States, Mexico
Mayo Clinic

No longer available

Stiripentol in Dravet Syndrome

Dravet Syndrome

United States
All India Institute of Medical Sciences, New Delhi

Recruiting

Cortical Excitability in West Syndrome Using Transcranial Magnetic Stimulation

West Syndrome

India
Izmir Katip Celebi University

Completed

Effects of Low Glycemic Index Diet in Children With Drug-resistant Epilepsy

Quality of Life | Oxidative Stress | Drug Resistant Epilepsy | Ketogenic Diet | Psychological Health

Turkey
NEMA Research, Inc.

Terminated

Efficacy and Safety of Intravenous Phenobarbital in Neonatal Seizures

Epilepsy, Benign Neonatal

United States, Jordan
UCB BIOSCIENCES GmbH
PRA Health Sciences

Completed

Study of Lacosamide as an Adjunctive Drug Treatment for Epilepsy in Patients With Brain Tumors (VIBES)

Brain Tumor Related Epilepsy (BTRE)

Italy, France, Germany, Netherlands, Spain, United Kingdom

Clinical Trials on Epilepsy, Tonic-Clonic

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