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Clinical Trials on Epilepsy, Tonic-Clonic

Total 46 results

NCT04282681

Withdrawn

XLTCS - Accelerometer Data Collection in an Epilepsy Monitoring Unit (EMU)

Conditions: Epilepsy, Tonic-Clonic
NCT04252846

Not yet recruiting

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy

Conditions: Idiopathic Generalized Epilepsy; Partial Onset Seizures; Generalised Tonic-Clonic Seizures
NCT03961568

Enrolling by invitation

Cenobamate Open-Label Extension Study for YKP3089C025

Conditions: Primary Generalized Tonic Clonic Seizures in the Setting of Idiopathic Generalized Epilepsy
NCT03940326

Completed

Levetiracetam Versus Valproate in Idiopathic Generalized Tonic-clonic Seizures

Conditions: Epilepsy, Idiopathic Generalized
NCT03831802

Recruiting

Embrace and Quality of Life

Conditions: Epilepsy, Tonic-Clonic
NCT03754582

Completed

A Study of Intravenous Perampanel in Japanese Participants With Epilepsy

Conditions: Epilepsy; Seizures
NCT03559673

No longer available

Compassionate Use Program With Lacosamide in Patients With Partial-onset or Generalized Tonic-clonic Seizures

Conditions: Epilepsies, Partial
NCT03446664

Recruiting

Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study

Conditions: Epilepsies, Partial; Epilepsy, Tonic-Clonic
NCT03059329

Completed

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adult Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures

Conditions: Partial Seizures (With or Without Secondary Generalized Seizures); Primary Generalized Tonic-clonic Seizures
NCT03059381

Active, not recruiting

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adolescence Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures

Conditions: Partial Seizures (With or Without Secondary Generalized Seizures); Primary Generalized Tonic-clonic Seizures
NCT02920060

Completed

Levetiracetam Versus Sodium Valproate in Children With Refractory Generalized Convulsive Status Epilepticus

Conditions: Grand Mal Status Epilepticus
NCT02736162

Completed

Study to Investigate Dosage, Efficacy, and Safety of Perampanel Given as Monotherapy in Patients With Epilepsy

Conditions: Epilepsy; Partial-Onset Seizures; Primary Generalized Tonic-Clonic Seizures
NCT02661919

Not yet recruiting

Assessment of the Emfit Mattress Sensor for Detection and Alarm of Night-time Generalized Tonic-clonic Seizures.

Conditions: Epilepsy; Seizures
NCT02555410

Completed

Seizure Detection and Warning System in Epilepsy Patients

Conditions: Epilepsy; Generalized Tonic-Clonic Seizures
NCT02408523

Completed

A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications

Conditions: Epilepsy
NCT02408549

Active, not recruiting

Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic Clonic Seizures

Conditions: Epilepsy
NCT02371200

Completed

Detecting Generalized Tonic-Clonic Seizures With a Seizure Detection and Warning System in Epilepsy Patients

Conditions: Epilepsy; Generalized Tonic-Clonic Seizures
NCT01874600

Active, not recruiting

Seizure Detection and Warning System for Epilepsy Patients

Conditions: Epilepsy
NCT01747915

Completed

A Safety, Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e., Grand Mal) Seizures.

Conditions: Generalized Tonic Clonic Seizures
NCT01586208

Completed

Refractory Status Epilepticus Treatment Study

Conditions: Grand Mal Status Epilepticus; Non-convulsive Status Epilepticus
NCT01465997

Completed

Evaluating Long Term Safety of Lacosamide (LCM) to Carbamazepine Controlled-release (CBZ-CR); Initial Monotherapy in Epilepsy Subjects 16 Years and Older

Conditions: Epilepsy; Monotherapy
NCT01463306

Completed

A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures

Conditions: Epilepsy, Partial Seizures; Epilepsy, Primary Generalized Tonic-Clonic Seizures
NCT01439438

Completed

Topiramate Bioequivalence Study Brazil - Fast

Conditions: Epilepsy, Tonic-Clonic
NCT01398956

Completed

An Open Label Study of L059 (Levetiracetam) in Japanese Epilepsy Subjects With Generalized Tonic-clonic Seizures

Conditions: Epilepsy; Generalized Tonic-clonic Seizures
NCT01393743

Completed

A Efficacy and Safety Study of Adjunctive Perampanel in Primary Generalized Tonic Clonic Seizures

Conditions: Seizure Disorder Generalized Tonic Clonic
NCT01292837

Completed

A Study of Levetiracetam in Japanese Pediatric Patients With Generalized Tonic-clonic Seizures

Conditions: Epilepsy; Generalized Tonic-clonic Seizures
NCT01243177

Completed

Trial Comparing the Efficacy and Safety of Lacosamide (LCM) to Carbamazepine Controlled-Release (CBZ-CR); Initial Monotherapy in Epilepsy; Subjects Aged 16 and Older

Conditions: Epilepsy; Monotherapy
NCT01228747

Completed

A Double-blind, Placebo-controlled Study of Levetiracetam in Epilepsy Patients With Generalized Tonic-clonic Seizures (Except Partial Seizures Evolving to Secondarily Generalized Seizures)

Conditions: Epilepsy; Generalized Tonic-Clonic Seizures
NCT01178437

Completed

Transcutaneous Non-invasive Stimulation of the Vagus Nerve for the Treatment of Difficult-to-treat Epilepsy

Conditions: Epilepsy
NCT01118949

Completed

Open-Label Study to Assess Lacosamide Safety as Add-on Therapy for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy

Conditions: Epilepsy
NCT01118962

Completed

Open-Label Extension Study to Assess the Safety and Seizure Frequency Associated With Lacosamide for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy

Conditions: Epilepsy
NCT00692003

Terminated

Adjunctive Zonisamide in Primary Generalised Tonic Clonic Seizures

Conditions: Epilepsy
NCT00510783

Completed

IV Keppra in the Emergency Department for Prevention of Early Recurrent Seizures

Conditions: Tonic-clonic Seizure
NCT00266604

Completed

A Study to Evaluate the Dosing, Effectiveness and Safety of Topiramate for the Treatment of Epilepsy

Conditions: Epilepsy; Seizures; Epilepsies, Partial; Epilepsy, Generalized; Seizures, Tonic-Clonic
NCT00236418

Completed

A Study of the Efficacy and Safety of Topiramate in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Conditions: Epilepsy; Seizures
NCT00236704

Completed

A Study of the Efficacy and Safety of Topiramate as "Add on" Treatment in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Conditions: Epilepsy; Seizures
NCT00231556

Completed

A Study on Safety and Efficacy of Two Doses of Topiramate as Monotherapy in the Treatment of Newly Diagnosed or Recurrent Epilepsy

Conditions: Epilepsy; Seizures; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic
NCT00208520

Unknown status

Second-Line Treatment Choice for Epilepsy

Conditions: Adults With Tonic Clonic Seizures and/or Partial Seizures
NCT00210652

Completed

An Open-Label Extension Study to Evaluate the Safety and Effectiveness of RWJ 333369 in Patients With Epilepsy

Conditions: Epilepsy; Epilepsies, Partial
NCT00160550

Completed

Study to Evaluate the Safety and Efficacy of Levetiracetam in Patients Suffering From Idiopathic Generalized Epilepsy With Primary Generalized Tonic-clonic Seizures

Conditions: Generalized Convulsive Epilepsy
NCT00150735

Completed

Monotherapy With Levetiracetam in Newly Diagnosed Patients Suffering From Epilepsy

Conditions: Generalized Epilepsy
NCT00150787

Completed

Monotherapy With Levetiracetam or Carbamazepine in Patients Suffering From Epilepsy.

Conditions: Epilepsy, Tonic-clonic
NCT00150813

Completed

Monotherapy With Levetiracetam in Patients Suffering From Epilepsy.

Conditions: Epilepsy, Tonic-clonic
NCT00104416

Completed

Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) Seizures

Conditions: Epilepsy, Tonic-Clonic
NCT00043901

Completed

Treatment Of Primary Generalized Tonic-Clonic Seizures With An Investigational New Drug

Conditions: Epilepsy, Tonic-Clonic
NCT00013845

Terminated

Evaluation and Treatment of Patients With Epilepsy

Conditions: Epilepsy

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Clinical Trials on Epilepsy, Tonic-Clonic