Clinical Trials on Epileptic Seizures

Total 1147 results

Jazz Pharmaceuticals

Completed

A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults (GWPCARE4)

Epilepsy | Lennox-Gastaut Syndrome

United States, Poland, Netherlands
Eisai Inc.

Completed

Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With Primary Generalized Tonic-Clonic Seizures

Partial Onset Seizures | Primary Generalized Tonic-Clonic Seizures | Secondarily Generalized Seizures

United States
National Institute of Neurological Disorders and...
Harborview Injury Prevention and Research Center

Completed

Phase III Double Blind Trial of Valproate Sodium for Prophylaxis of Post Traumatic Seizures

Post-Traumatic Seizure Disorder | Head Injuries
Assistance Publique Hopitaux De Marseille

Recruiting

Creation of a Register of Patients With Neonatal-onset Epileptic Encephalopathy (IMPROVE)

Epileptic Encephalopathy

France
KTO Karatay University

Completed

The Individual and Family Self Management Theory Based Epilepsy Education Program's Effectiveness

Quality of Life | Epilepsy; Seizure | Self Management

Turkey
Lady Hardinge Medical College

Unknown

Evaluation of the Modified Atkins Diet in Children With Epileptic Spasms

Epileptic Spasms

India
Number 2 Children's Hospital, Ho Chi Minh City
University Hospital, Geneva; Swiss National Science Foundation; University of... and other collaborators

Recruiting

Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam

Epileptic Encephalopathy | Whole Exome Sequencing

Vietnam
Takeda
Ovid Therapeutics Inc.

Completed

Study of TAK-935 as an Adjunctive Therapy in Participants With Developmental and/or Epileptic Encephalopathies

Developmental and/or Epileptic Encephalopathies

United States
Imagine Institute

Not yet recruiting

Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data (DEE-RETRO)

Developmental and Epileptic Encephalopathy
All India Institute of Medical Sciences, New Delhi

Unknown

Comparison of Efficacy Between Suggestion Method During Video EEG Recording by Verbal Suggestion in Isolation and Verbal Suggestion Along With Cotton Swab or Tuning Fork for Inducing the Paroxysmal Event in Children Aged 5 to 18 Years With Suspected Psychogenic Nonepileptic Events

EEG, Psychogenic Non Epileptic Events
Children's Hospitals and Clinics of Minnesota

Completed

Animal Assisted Therapy in a Pediatric Setting (AAT)

Stroke | Behavior Problems | Feeding Disorder | Developmental Delays | Cancers | Global Developmental Delay | Seizures Disorders | Developmental Delay in Feeding

United States
Eisai Inc.

Terminated

Study of Perampanel as Adjunctive Treatment for Inadequately Controlled Seizures Associated With Lennox-Gastaut Syndrome

Lennox-Gastaut Syndrome (LGS)

Korea, Republic of, United States, Australia, Belgium, Japan, Czechia, India
University of Erlangen-Nürnberg Medical School
University of Aarhus; Royal College of Surgeons, Ireland; European Commission; Philipps... and other collaborators

Withdrawn

Hybrid Device DIALYTRODE for Multimodal Neuro-monitoring of Patients With Brain Injury and Status Epilepticus

Epilepsy | Brain Injuries

Germany
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Safety, Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e., Grand Mal) Seizures.

Generalized Tonic Clonic Seizures

Korea, Republic of, United States, Austria, Serbia, India, Spain, Poland, Malaysia, China, Bulgaria, Denmark, Greece, Hungary, United Kingdom, Belarus, France, Montenegro, Philippines, Romania, Russian Federation, Slovakia, Ukraine, Lebano... and more
Lundbeck LLC

Completed

A Study of the Structure and Function of the Retina in Adult Patients With Refractory Complex Partial Seizures Treated With Vigabatrin (Sabril®)

Adult Refractory Complex Partial Seizures

United States
University Hospital, Bordeaux

Completed

Quality of Life and Psychogenic Nonepileptic Seizures. (PronoCNEP)

Psychogenic Nonepileptic Seizures (PNESs)

France
Yale University
Monash University

Enrolling by invitation

International Post-Stroke Epilepsy Research Repository (IPSERR)

Stroke | Epilepsy | Post Stroke Seizure | Post Stroke Epilepsy

United States
Emory University
The University of Texas Health Science Center, Houston; National Institute... and other collaborators

Completed

Preventing Depression in People With Epilepsy: an Extension of Project UPLIFT

Depression | Epilepsy | Depressive Symptoms | Seizure Disorder

United States
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures (X-ACKT)

Primary Generalized Tonic-Clonic Seizures

United States, Australia, Spain, United Kingdom, Bulgaria, Poland, Czechia, Canada, Portugal, Croatia, Italy
University of Michigan

Completed

Seizure Prophylaxis in Aneurysm Repair (SPAR)

Intracranial Aneurysms | Seizure

United States
Valexfarm

Completed

Remegal Fixed Dose as Adjunctive Therapy in Patients With Partial Seizures

Epilepsy | Complex Partial Seizures | Simple Partial Seizures | Partial Seizures With Secondary Generalization

Russian Federation
University of Southern California
Vitaflo International, Ltd

Terminated

Betaquik as an Adjunct to Dietary Management of Epilepsy in Adults on the Modified Atkins Diet

Epilepsy | Seizures | Ketosis | Seizure Disorder | Ketogenic Dieting | Epilepsy Intractable

United States
Al-Azhar University

Recruiting

Epileptic Syndromes in Infants and Early Childhood

Epileptic Syndromes

Egypt
University Hospital, Brest

Active, not recruiting

Comitial Prophylaxis in Neurosurgery in Patients Who Have Undergone Intracranial Surgery Programmed Supratentorial Surgery (Exeresis or Biopsy) Between 2019 and 2022 (PRO-CON)

Anti-epileptic Prophylaxis in Intracranial Neurosurgery

France
Lviv National Medical University

Unknown

Post Stroke Epileptic Seizures Risk Forecast (POSTER-1)

Stroke | Post Stroke Seizure | Post Stroke Epilepsy

Ukraine
University of California, San Diego
University of Minnesota; Rady Children's Hospital, San Diego; Middlemore Hospital... and other collaborators

Recruiting

A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures (NEOLEV3)

Hypoxic-Ischemic Encephalopathy | Neonatal Encephalopathy | Neonatal Seizure | Seizure Newborn

United States, New Zealand
Cook Children's Health Care System

No longer available

Expanded Access Use of Stiripentol in Dravet Syndrome or Sodium Channel Mutation Epileptic Encephalopathies

Dravet Syndrome | Epileptic Encephalopathies Associated With SCN1A Mutations

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures

Epilepsy, Partial Seizures | Epilepsy, Primary Generalized Tonic-Clonic Seizures

United States, Korea, Republic of, Taiwan, Lebanon, Singapore, Malaysia, China, Spain, Bulgaria, Czechia, United Kingdom, Israel, Russian Federation, France, Belarus, Belgium, Bosnia and Herzegovina, Germany, Greece, Hungary, India and more
Eisai Co., Ltd.

Completed

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adolescence Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures (FYC02T)

Partial Seizures (With or Without Secondary Generalized Seizures) | Primary Generalized Tonic-clonic Seizures

Japan
Eisai Inc.

Completed

Perampanel as Adjunctive Therapy in Pediatrics With Partial Onset Seizures or Primary Generalized Tonic Clonic Seizures

Partial-Onset or Primary Generalized Tonic-Clonic Seizures

Canada, France, Italy, Korea, Republic of, Spain, United States, Belgium, Czechia, Hungary, Japan, Latvia, Poland
Child Advocacy International
United States Agency for International Development (USAID); John Snow, Inc.

Completed

Evaluation of Essential Surgical Skills-Emergency Maternal and Child Health Training

Heart Failure | Sepsis | Asthma | Coma | Seizure

Pakistan
Kenneth Myers, MD

Completed

Memantine for Epileptic Encephalopathy

Epileptic Encephalopathy, Childhood-Onset

Canada
International Centre for Diarrhoeal Disease Research...

Completed

RCT of Efficacy of Amoxicillin Over Ampicillin on Severe Pneumonia

Hypoxia | Feeding; Difficult, Newborn | Altered Mental Status | Convulsion, Non-Epileptic | Treatment Failure | Lethargy

Bangladesh
Eisai Co., Ltd.

Completed

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adult Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures (FYC01S)

Partial Seizures (With or Without Secondary Generalized Seizures) | Primary Generalized Tonic-clonic Seizures

Japan
UCB Japan Co. Ltd.

Completed

A Study of Levetiracetam as Monotherapy or Adjunctive Treatment of Partial Seizures in Pediatric Epileptic Subjects Ranging From 1 Month to Less Than 4 Years of Age (PEACH)

Partial Seizures

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Pregabalin Epilepsy Add-On Trial

Partial Seizures

Korea, Republic of
Ehsan M saied

Unknown

The Pattern of Pediatric Seizures at Al-Arish Central Hospital - North Sinai

Convulsive Seizures
Richard H. Haas
University of California, San Diego; Food and Drug Administration (FDA); UCSF... and other collaborators

Completed

Efficacy of Intravenous Levetiracetam in Neonatal Seizures (NEOLEV2)

Neonatal Seizures

United States
Duke University

Completed

Nonconvulsive Seizure Identification on Quantitative EEG by Neuro ICU Nurses

Nonconvulsive Seizures

United States
University College Cork
University College, London; Wellcome Trust

Completed

ANSeR- The Algorithm for Neonatal Seizure Recognition Study (ANSeR)

Neonatal Seizures

United Kingdom, Ireland, Netherlands, Sweden
Abbott

Completed

A Study for Treatment of Partial Seizures in Children

Partial Seizures

United States
Novartis

Completed

Safety and Efficacy of Oxcarbazepine Monotherapy in Adults With Partial Seizures

Epilepsy, Partial Seizures

Russian Federation
University of California, San Francisco
The ZOLL Foundation

Recruiting

buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest (RESTORE)

Seizures | Heart Arrest | Hypoxia-Ischemia, Brain | Status Epilepticus | Refractory Status Epilepticus | Anoxic-Ischemic Encephalopathy | Anoxia-Ischemia, Cerebral

United States
Children's Hospital of Fudan University
Second Affiliated Hospital of Wenzhou Medical University; Guangzhou Women and... and other collaborators

Terminated

Levetiracetam Treatment of Neonatal Seizures

Neonatal Seizures

China
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

Pregabalin In Partial Seizures (PREPS): An Open-Label, Multicenter Add On Therapy Trial (PREPS MEXICO)

Partial Seizures

Mexico
Aatif Husain
UCB Pharma

Completed

Intravenous Lacosamide Compared With Fosphenytoin in the Treatment of Patients With Frequent Nonconvulsive Seizures (TRENdS)

Nonconvulsive Seizures

United States
Eisai Limited

Completed

A Study to Assess the Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Extension Study)

Partial Seizures

Italy
Eisai Inc.

Completed

Evaluating the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures

Partial Seizures

China
Eisai Inc.

Completed

Evaluation of the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Added Antiepileptic Drug

Partial Seizures

Italy
UCB Japan Co. Ltd.

Completed

A Study of Levetiracetam in Japanese Pediatric Patients With Generalized Tonic-clonic Seizures

Epilepsy | Generalized Tonic-clonic Seizures

Japan

Clinical Trials on Epileptic Seizures

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