Clinical Trials on Esophageal Gastric Cardia Type Metaplasia

Total 2433 results

HiFiBiO Therapeutics

Recruiting

A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Colorectal Cancer | Non Small Cell Lung Cancer

Spain, United States, Italy
Tvardi Therapeutics, Incorporated
M.D. Anderson Cancer Center

Active, not recruiting

Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers

Melanoma | Breast Cancer | Colorectal Cancer | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Hepatocellular Cancer

United States
M.D. Anderson Cancer Center

Completed

Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy

Malignant Solid Neoplasm | Gastric Carcinoma | Malignant Peritoneal Neoplasm | Colorectal Carcinoma | Carcinomatosis | Appendix Carcinoma

United States
Memorial Sloan Kettering Cancer Center
Novartis

Completed

Effect of Imatinib on Bone Metabolism in Patients With Chronic Myelogenous Leukemia or Gastrointestinal Stromal Tumors

Leukemia | Gastric Cancer | Chronic Myelogenous Leukemia

United States
Ewha Womans University Mokdong Hospital

Enrolling by invitation

The Effect of SGLT-2 Inhibitor in Patient With Atrial Fibrillation and Diabetes Mellitus

Diabetes Mellitus, Type 2 | Atrial Fibrillation | SGLT-2 Inhibitor

Korea, Republic of
Mayo Clinic

Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors (PNeoVCA)

Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 and other conditions

United States
University of Colorado, Denver
Haemonetics Corporation

Recruiting

Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection (TEG)

Colorectal Cancer | Esophageal Cancer | Lung Adenocarcinoma | Pancreas Cancer | Liver Cancer | Biliary Cancer | Control

United States
Donald Mathews
Respiratory Motion, Inc.

Unknown

An Evaluation of the Utility of the ExSpiron Respiratory Variation Monitor During Upper GI Endoscopy

Stomach Neoplasms | Biliary Tract Diseases | Barrett Esophagus | Carcinoma, Pancreatic Ductal

United States
Five Prime Therapeutics, Inc.

Completed

Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors

Gastric Cancer | Advanced Solid Tumors | Transitional Cell Carcinoma of the Bladder

Korea, Republic of, United States, Taiwan
Ipsen

Terminated

Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.

Gastric Cancer | Colorectal Cancer | Bone Cancer | Squamous Cell Carcinoma of the Head and Neck | Advanced Cancer | Recurrent Disease | Pancreatic Ductal Adenocarcinoma | Metastatic Tumours

United States, France, Belgium, Switzerland, Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Akt/ERK Inhibitor ONC201 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Refractory Mantle Cell Lymphoma | Central Nervous System Lymphoma | Gastric Mantle Cell Lymphoma | Splenic Mantle Cell Lymphoma

United States
Eli Lilly and Company

Completed

A Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced Cancer

Renal Cell Carcinoma | Non-Small Cell Lung Cancer | Gastric Adenocarcinoma | Advanced Cancer | Hepatocellular Cancer | Gastroesophageal Junction Adenocarcinoma

United States
National Cancer Institute (NCI)

Withdrawn

Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Stage IV Non-Small Cell Lung Cancer | Metastatic Pancreatic Adenocarcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast... and other conditions
Irina Ermolaeva

Recruiting

RE-ELECT. Dabigatran vs Warfarin in AF Patients With T2DM and CKD (RE-ELECT)

Chronic Kidney Diseases | Atrial Fibrillation | T2DM (Type 2 Diabetes Mellitus)

Russian Federation
AstraZeneca

Completed

The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).

Gastrointestinal Stromal Tumors | Soft Tissue Sarcomas

United Kingdom
Minneamrita Therapeutics LLC
Translational Drug Development

Recruiting

A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors (Minnelide 101)

Breast Cancer | Gastric Cancer | Pancreatic Cancer | Solid Tumor | Advanced Cancer | Colo-rectal Cancer | Prostate Cancer Metastatic | Solid Carcinoma | Solid Carcinoma of Stomach | Cancer of Stomach

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

The RIOT Trial: Re-Defining Frailty and Improving Outcomes With Prehabilitation for Pancreatic, Liver, or Gastric Cancer (RIOT)

Malignant Solid Neoplasm | Gastric Carcinoma | Pancreatic Carcinoma | Adult Liver Carcinoma

United States
Incyte Corporation

Active, not recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Cervical Cancer | Nasopharyngeal Carcinoma | Mesothelioma | Advanced Solid Tumor | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Merkel Cell Carcinoma | HepatoCellular Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1)

France, United States, Japan, Belgium, Australia
Tempus AI
GlaxoSmithKline

Active, not recruiting

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors (PAVO)

Melanoma | Head and Neck Cancer | Pancreatic Cancer | Esophageal Cancer | Solid Tumor | Metastatic Cancer | Endometrial Cancer | Urologic Cancer | Breast Tumor | Locally Advanced Solid Tumor | Lung Tumor | Colon Tumor, Malignant

United States
South Karelia, Social and Health Care District

Completed

RENEWING HEALTH - RegioNs of Europe WorkINg Together for HEALTH

Coronary Artery Disease | Heart Failure | Atrial Fibrillation | Type 2 Diabetes | Other Arrhythmias

Finland
Medical University of Vienna

Completed

Atropine for Prevention of Dysrhythmias Caused by Percutaneous Ethanol Instillation for Hepatoma Therapy (atropinePEI)

Arrhythmia | Respiratory Arrest

Austria
Yang Yang

Unknown

PD-1 Knockout EBV-CTLs for Advanced Stage Epstein-Barr Virus (EBV) Associated Malignancies

Stage IV Adult Hodgkin Lymphoma | Stage IV Nasopharyngeal Carcinoma | Stage IV Diffuse Large B-Cell Lymphoma | Stage IV Gastric Carcinoma | T-Cell Lymphoma Stage IV

China
Loren Mell, MD

Recruiting

QUantitative Assessment of Swallowing After Radiation (QUASAR) (QUASAR)

Head and Neck Cancer | Dysphagia | Oropharyngeal Dysphagia | Oropharynx Cancer | Oropharynx Squamous Cell Carcinoma

United States
CytomX Therapeutics

Completed

PROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCL

Head and Neck Cancer | Esophageal Cancer | Non Small Cell Lung Cancer | Diffuse Large B Cell Lymphoma | Solid Tumor, Adult

United States, Spain, Korea, Republic of, United Kingdom
University Health Network, Toronto
Takara Bio Inc.

Active, not recruiting

Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors

Melanoma | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Bladder Cancer | Liver Cancer | Synovial Sarcoma | NY-ESO-1 Expressing Solid Tumors in HLA-A2 Positive Patients

Canada
OncoC4, Inc.
National Cancer Institute (NCI)

Recruiting

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC (PRESERVE-001)

Cervical Cancer | Small Cell Lung Cancer | Adenoid Cystic Carcinoma | Metastatic Renal Cell Carcinoma | Metastatic Colorectal Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Breast Cancer | Advanced Solid Tumor | Metastatic Melanoma | Pancreas Cancer | Metastatic... and other conditions

United States, Australia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung... and other conditions

United States
Sorrento Therapeutics, Inc.

Withdrawn

CAR-T Intraperitoneal Infusions for CEA-Expressing Adenocarcinoma Peritoneal Metastases or Malignant Ascites (IPC)

Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreas Cancer | Peritoneal Carcinomatosis | Peritoneal Metastases | Carcinoembryonic Antigen

United States
Cancer Research UK

Unknown

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom

Lymphoma | Kidney Cancer | Pancreatic Cancer | Esophageal Cancer | Brain and Central Nervous System Tumors | Bladder Cancer | Intraocular Melanoma | Melanoma (Skin) | Transitional Cell Cancer of the Renal Pelvis and Ureter

United Kingdom
University of Nebraska
National Cancer Institute (NCI)

Completed

Capecitabine, Epirubicin, and Carboplatin in Treating Patients With Progressive, Unresectable, or Metastatic Cancer

Gastric Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
The First Affiliated Hospital of Xiamen University
LanZhou University; Eastern Hepatobiliary Surgery Hospital

Unknown

Proximal Roux-en-y Gastrojejunal Anastomosis on Delayed Gastric Emptying After Pylorus-resecting Pancreaticoduodenectomy

Pancreatic Cancer | Bile Duct Cancer | Duodenal Cancer

China
Silesian Centre for Heart Diseases
Medical Research Agency, Poland

Not yet recruiting

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Heart Failure | Breast Cancer | Breast Diseases | Cardiotoxicity | Molecular Mechanisms of Pharmacological Action | Angiotensin Receptor Antagonists | Neoplasm, Breast | Cardiac Toxicity | Angiotensin II Type 1 Receptor Blockers | Cancer, Therapy-Related | Antihypertensive Agents | Sacubitril/Valsartan | Cancer...

Poland
SOLTI Breast Cancer Research Group
Novartis

Recruiting

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors (ACROPOLI)

Melanoma | Sarcoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Uterine Carcinosarcoma | Mesothelioma | Cholangiocarcinoma | Lung Adenocarcinoma | Triple Negative Breast Cancer | Epithelial Ovarian Cancer | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal... and other conditions

Spain
University of Puerto Rico
National Cancer Institute (NCI)

Recruiting

Familial Colorectal Cancer Registry in Hispanics (PURIFICAR)

Colorectal Neoplasms | Gastric Cancer | Colorectal Cancer | Lynch Syndrome | Colorectal Adenoma

Puerto Rico
Bristol-Myers Squibb

Recruiting

A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors

Melanoma | Carcinoma, Renal Cell | Cervical Cancer | Pancreatic Adenocarcinoma | Ovarian Neoplasms | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Neoplasms | Urothelial Carcinoma | Microsatellite Stable Colorectal Cancer | Non-Small-Cell Lung Cancer | Gastric/Gastroesophageal Junction...

United States, Australia, Italy, Germany, Spain, Canada, Israel, Japan
University College, London
National Institute for Health Research, United Kingdom; Myotonic Dystrophy... and other collaborators

Recruiting

Profile of Dysphagia in Myotonic Dystrophy Type 1 (DM1) (SwallowDM1)

Myotonic Dystrophy 1 | Dysphagia, Oropharyngeal

United Kingdom
Ascentage Pharma Group Inc.
Suzhou Yasheng Pharmaceutical Co., Ltd.

Recruiting

APG-2449 in Patients With Advanced Solid Tumors

Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Malignant Pleural Mesothelioma | Advanced Solid Cancer

China
Johnson & Johnson Pharmaceutical Research & Development...

Completed

The Effect of Epoetin Alfa on the Anemia of Patients With Selected Cancers Receiving Chemotherapy

Lymphoma | Breast Cancer | Multiple Myeloma | Anemia | Ovarian Cancer | Prostate Cancer | Neoplasm | Esophagus Cancer | Carcinoma, Small Cell Lung
Memorial Sloan Kettering Cancer Center

Completed

The Reproducibility Of Diffusion Weighted Magnetic Resonance Imaging For Neuroendocrine Tumor Liver Metastases

Gastro-enteropancreatic Neuroendocrine Tumor | Secondary Malignant Neoplasm of Liver

United States
Baylor Research Institute

Completed

Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome

Type 2 Diabetes Mellitus | Chronic Kidney Disease | Left Ventricular Diastolic Dysfunction

United States
Sanofi

Completed

Observatory on Elderly Patients "Les S.AGES"

Diabetes Mellitus, Type 2 | Chronic Pain | Atrial Fibrillation

France
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Effect of Patient Management Based on Continuous Continuous Glucose Monitoring on Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes and Moderate to Severe Coronary Artery Stenosis

Diabetes Mellitus, Type 2 | Major Adverse Cardiac Events

China
Hospital Universitario de Fuenlabrada
Spanish Association of Surgeons (AEC)

Active, not recruiting

Gastric Bypass With Different Lengths of the Bilipancreatic Limb (BPG-1)

Hypertension | Obesity | Diabetes Mellitus, Type 2 | Dyslipidemias | Sleep Apnea | Laparoscopic-Roux-en-Y Gastric Bypass

Spain
First Affiliated Hospital, Sun Yat-Sen University

Unknown

Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery

Gastric Cancer | Colorectal Cancer | Surgical Site Infection | Inflammatory Bowel Disease | Gastrointestinal Stromal Tumor | Diverticula | Complications of Surgical Procedures

China
Sensei Biotherapeutics, Inc.
Regeneron Pharmaceuticals

Recruiting

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Melanoma | Sarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Bladder Cancer | Cervix Cancer | Advanced Solid Tumor | Advanced Cancer | Colon Cancer | Thyroid Cancer | Solid Tumor... and other conditions

United States
Assistance Publique Hopitaux De Marseille

Completed

Evaluation of PET-CT Using Somatostatin Agonists Labeled With Gallium68 in Neuroendocrine Tumors (DOTATATENET)

Gastro-Entero-Pancreatic Tumors (GEPs)

France
FeRx

Completed

Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Liver

Melanoma | Sarcoma | Stomach Neoplasms | Gastrointestinal Neoplasms | Breast Neoplasms | Lung Neoplasms | Liver Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Metastases, Neoplasm | Cholangiocarcinoma

United States, Germany
CytoMed Therapeutics Pte Ltd

Unknown

Haplo / Allogeneic NKG2DL-targeting Chimeric Antigen Receptor-grafted γδ T Cells for Relapsed or Refractory Solid Tumour

Sarcoma | Nasopharyngeal Carcinoma | Gastric Cancer | Colorectal Cancer | Prostate Cancer | Triple Negative Breast Cancer

Malaysia
National Cancer Institute (NCI)

Withdrawn

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Cervical Carcinoma | Recurrent Melanoma | Vaginal Carcinoma | Esophageal Carcinoma | Mucosal Melanoma | Mucosal Melanoma of the Head and Neck | Oral Cavity Mucosal Melanoma | Stage II Vulvar Cancer AJCC v7 | Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 and other conditions

United States
Mayo Clinic

Recruiting

Predicting Response to Immune Checkpoint Inhibitors Across Solid Tumors Using a Live Tumor Diagnostic Platform (CYBRID-04)

Metastatic Lung Non-Small Cell Carcinoma | Metastatic Clear Cell Renal Cell Carcinoma | Resectable Lung Non-Small Cell Carcinoma | Metastatic Malignant Solid Neoplasm | Metastatic Bladder Urothelial Carcinoma | Metastatic Colorectal Carcinoma | Metastatic Triple-Negative Breast Carcinoma | Locally... and other conditions

United States

Clinical Trials on Esophageal Gastric Cardia Type Metaplasia

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CROs in Guinea

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