Clinical Trials on Exocrine Pancreatic Insufficiency: Cystic Fibrosis in United States

Total 3171 results

First Wave Bio, Inc.

Completed

OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic Fibrosis

Cystic Fibrosis (CF) | Exocrine Pancreatic Insufficiency (EPI)

United States, Poland
First Wave Bio, Inc.

Completed

OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis (OPTION)

Cystic Fibrosis (CF) | Exocrine Pancreatic Insufficiency (EPI)

United States, Poland
Forest Laboratories

Completed

Safety and Efficacy Study of 2 Pancreatic Enzymes for Treatment of Exocrine Pancreatic Insufficiency in Cystic Fibrosis.

Exocrine Pancreatic Insufficiency: Cystic Fibrosis

United Kingdom, Italy, Belgium, Bulgaria, France, Germany, Poland
National Institute of Diabetes and Digestive and...
Cystic Fibrosis Foundation

Completed

MRI to Characterize and Predict CF Liver Disease in PUSH Cohort

Pancreatic Insufficiency | Cystic Fibrosis Liver Disease

United States
National Institute of Diabetes and Digestive and...

Recruiting

Diagnosis and Treatment of Patients With Cystic Fibrosis

Diabetes | Cystic Fibrosis | Liver Disease or Abnormalities | Pancreatic Insufficiency (Exocrine and Endocrine)

United States
Avanti Polar Lipids, Inc.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Study of LYM-X-SORB™ to Improve Fatty Acid and Choline Status in Children With CF and PI

Cystic Fibrosis | Pancreatic Insufficiency

United States
Children's Hospital of Philadelphia
Chiesi USA, Inc.

Completed

Proton Pump Inhibitors (PPI) and Fat Absorption in Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)

Cystic Fibrosis | Pancreatic Insufficiency

United States
Solvay Pharmaceuticals

Completed

Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Cystic Fibrosis | Pancreatic Exocrine Insufficiency

United States
Solvay Pharmaceuticals

Completed

Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency (PEI) Due to Cystic Fibrosis (CF)

Cystic Fibrosis | Pancreatic Exocrine Insufficiency

United States
Digestive Care, Inc.

Completed

Evaluation of the Safety and Efficacy of Pancrecarb® MS-16 in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
Arbelaez, Ana Maria
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Novo... and other collaborators

Completed

Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis

Pancreatic Insufficiency | Cystic Fibrosis Related Diabetes

United States
Forest Laboratories

Completed

Efficacy and Safety of Ultrase® MT20 in Improving the Coefficient of Fat Absorption (CFA) in Children With Cystic Fibrosis (CF) and Pancreatic Insufficiency (PI)

Cystic Fibrosis | Pancreatic Insufficiency

United States
Anthera Pharmaceuticals
Cystic Fibrosis Foundation

Completed

Oral TheraCLEC™ - Total in Cystic Fibrosis Subjects With Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Pancreatic Insufficiency

United States
Nordmark Arzneimittel GmbH & Co. KG
Parexel

Completed

Efficacy and Tolerability of NM-BL in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis

Digestive System Diseases | Respiratory Tract Diseases | Lung Diseases | Cystic Fibrosis | Pancreatic Insufficiency

United States
Digestive Care, Inc.

Withdrawn

Open Label Safety Study of DCI-1020 in Pediatric Cystic Fibrosis (CF) Patients

Digestive System Diseases | Cystic Fibrosis | Exocrine Pancreatic Insufficiency | Pancreatic Disease

United States
University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

Beta-cell Response to Incretin Hormones in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
University of Pennsylvania
Children's Hospital of Philadelphia

Completed

Effect of Chronic Incretin-based Therapy in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
The University of Texas Health Science Center,...

Recruiting

A Prospective Study To Identify Predictive Biological Markers In Blood And Cyst Fluid Aspirates From Patients With Pancreatic Cyst Lesions

Pancreatic Cystic Lesions

United States
Forest Laboratories

Completed

Study to Evaluate the Safety and Efficacy of EUR-1008 (APT-1008) Pancreatic Enzyme Product in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
GlycosBio, Inc.
Baylor College of Medicine

Completed

Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic Fibrosis

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF)

Cystic Fibrosis | Pancreatic Insufficiency

United States
University of Nebraska

Not yet recruiting

Chemoprevention With Tamoxifen in Pre-Invasive Pancreas Mucinous Cystic Neoplasms Not Undergoing Immediate Resection (MCN_Tam)

Pancreatic Cyst | Pancreatic Mucinous Cystic Neoplasm

United States
National Institute of Diabetes and Digestive and...
Cystic Fibrosis Foundation

Completed

Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis (PUSH)

Cystic Fibrosis | Pancreatic Insufficiency

United States, Canada
Johns Hopkins University
Lustgarten Foundation

Recruiting

Early Detection of Pancreatic Cystic Neoplasms

Pancreatic Mucinous-Cystic Neoplasm | Pancreatic Cysts | Intraductal Papillary Mucinous Neoplasm | Solid Pseudopapillary Tumour of the Pancreas | Cystic, Mucinous and/or Serous Neoplasm

United States
First Wave BioPharma, Inc.

Completed

Study to Assess an Enteric Microgranule Formulation of Adrulipase in Patients With Cystic Fibrosis (SPAN)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Children's Hospital of Philadelphia
Solvay Pharmaceuticals

Completed

Malabsorption Blood Test:Toward a Novel Approach to Quantify Steatorrhea (MBT)

Cystic Fibrosis | Pancreatic Insufficiency

United States
Forest Laboratories

Completed

A Study to Evaluate the Mode of Administration and Safety of EUR-1008 (APT-1008) in Infants 1 to 12 Months of Age

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

PR-018: An Open-Label, Safety Extension of Study PR-011

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
AbbVie

Completed

A Study to Compare US Marketed Creon Manufactured With a Modernized Process at an Alternate Manufacturing Site and Manufactured With the Approved Manufacturing Process at an Alternate Active Pharmaceutical Ingredient Site, in Participants With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis

Cystic Fibrosis

United States
Anthera Pharmaceuticals

Completed

EASY: Extended Access to Sollpura Over Years

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States, Hungary, Israel, Poland, Spain, Czechia
Digestive Care, Inc.
University of North Carolina, Chapel Hill

Terminated

Intraduodenal Aspiration Study to Assess the Bioavailability of Oral Pancrecarb® Compared to Placebo Control

Cystic Fibrosis | Chronic Pancreatitis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Study of Pancreatic Enzyme Product in Pediatric Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Safety and Efficacy Study of ULTRASE® MT20 in Participants With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (PI)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Anthera Pharmaceuticals

Completed

Liprotamase Efficacy Trial in Patients With Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency (DIGEST)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Anthera Pharmaceuticals

Unknown

RESULT: Reliable, Emergent Solution Using Liprotamase Treatment

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States, Hungary, Israel, Lithuania, Poland, Spain, United Kingdom
University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Diabetes | Cystic Fibrosis | Pancreatic Insufficiency | Abnormal Glucose Tolerance

United States
Anthera Pharmaceuticals

Completed

SOLUTION: Study of Oral Liprotamase Unit-Matched Therapy Of Non-Porcine Origin in Patients With Cystic Fibrosis

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States, Hungary, Israel, Poland, Spain, Canada, Czechia
Anthera Pharmaceuticals

Completed

Open-Label Phase III Long-Term Safety Trial of Liprotamase (DIGEST)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Anthera Pharmaceuticals

Completed

SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic Fibrosis (SIMPLICITY)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
University of Colorado, Denver
Cystic Fibrosis Foundation

Terminated

Sensor Augmented Pump (SAP) Therapy for Inpatient CFRD Management

Cystic Fibrosis-related Diabetes | Cystic Fibrosis Pulmonary Exacerbation | Cystic Fibrosis in Children

United States
Children's Hospital Medical Center, Cincinnati
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Behavioral & Nutritional Treatment to Help CF Preschoolers Grow

Cystic Fibrosis | Pancreatic Cystic Fibrosis

United States
Manchester University NHS Foundation Trust

Completed

The Use of Novel Diagnostic Tools to Increase Detection of Early Fibrosis in Cystic Fibrosis Related Liver Disease to Improve Clinical Management

Cystic Fibrosis | Liver Fibroses | Cystic Fibrosis Liver Disease

United Kingdom
Ohio State University
AbbVie

Active, not recruiting

Post Acute Pancreatitis Pancreatic Exocrine Insufficiency (PAPPEI)

Acute Pancreatitis

United States
AbbVie

Completed

Study to Evaluate Symptoms of Exocrine Pancreatic Insufficiency in Adult Participants With Cystic Fibrosis or Chronic Pancreatitis Treated With Creon

Cystic Fibrosis | Chronic Pancreatitis

United States
University of Medicine and Pharmacy Craiova
M.D. Anderson Cancer Center; Massachusetts General Hospital; University College... and other collaborators

Terminated

Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic Lesions (CINE-Cyst)

Cystadenocarcinoma | Pancreatic Mucinous-Cystic Neoplasm | Pancreatic Cysts | Intraductal Papillary Mucinous Neoplasm | Solid Pseudopapillary Tumour of the Pancreas | Serous Cystadenoma

United States, Denmark, Romania, United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Tolerability of Pancrelipase Microtablet (MT) Capsules for the Treatment of Cystic Fibrosis-dependent Exocrine Pancreatic Insufficiency

Malabsorption Syndromes | Cystic Fibrosis | Steatorrhea | Exocrine Pancreatic Insufficiency

United States, Canada
University Hospitals Cleveland Medical Center

Completed

Glycemic Characterization and Pancreatic Imaging Correlates in Cystic Fibrosis (CFCGM)

Cystic Fibrosis | Hepatic Steatosis | Cystic Fibrosis-related Diabetes | Cystic Fibrosis Liver Disease | Pancreatic Steatosis

United States
Mack Biotech, Corp.

Completed

Airway Clearance System (K031876) Phase IV Device Efficacy

Cystic Fibrosis, Pulmonary

United States
AbbVie

Terminated

A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI)

Exocrine Pancreatic Insufficiency (EPI)

United States
Emory University

Completed

Pancreatic Insufficiency Secondary to Tobacco Exposure

Pancreatic Insufficiency

United States

Clinical Trials on Exocrine Pancreatic Insufficiency: Cystic Fibrosis in United States

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