Clinical Trials on Exposure to Chemical Pollution, Occupational

Total 298 results

Indivior Inc.

Active, not recruiting

Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users

Moderate to Severe Opioid-use Disorder

United States, Canada
University of Florida
National Institute on Alcohol Abuse and Alcoholism (NIAAA); American Psychological...

Terminated

Impulsivity and Alcohol Response (IDEA)

Alcohol Use Disorder (AUD) | Subjective Response to Alcohol (SR)

United States
Duke University

Completed

Hypercapnia: Cognitive Effects and Monitoring

Exercise | Hypercapnia | Immersion | Diving | Nitrogen Narcosis

United States
Institut de Recherches Internationales Servier
Celgene Corporation

Active, not recruiting

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Untreated AML | Newly Diagnosed Acute Myeloid Leukemia (AML) | AML Arising From Myelodysplastic Syndrome (MDS) | AML Arising From Antecedent Hematologic Disorder (AHD) | AML Arising After Exposure to Genotoxic Injury

United States, Germany, Netherlands
Genelex Corporation
University of Utah

Completed

YouScript IMPACT Registry (IMPACT)

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme Deficiency | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome... and other conditions

United States
Beni-Suef University

Completed

PRF in Management of Chronic Multiple Oral Ulcers

Oral Ulcer Due to Pemphius Vularis | Oral Ulcer Due to Benign Mucous Membrane Pemphioid | Oral Ulcer Due to Steven Johnson's Syndrome

Egypt
New York State Psychiatric Institute
Columbia University; Weill Medical College of Cornell University; National Institute... and other collaborators

Active, not recruiting

Facilitating Opioid Care Connections

Opioid Use | Opioid Court Model | Medication to Treat Opioid Use Disorder

United States
Genelex Corporation
Harding University

Completed

Pharmacogenetic Testing Among Home Health Patients

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme... and other conditions

United States
Taipei Veterans General Hospital, Taiwan

Unknown

Entecavir for Biological Agents Associated HBV Reactivation in Inflammatory Arthritis Patients

Rheumatoid Arthritis | Exposure to Hepatitis B Virus | Hepatitis B Reactivation

Taiwan
Texas Tech University
National Cancer Institute (NCI); American Cancer Society, Inc.

Completed

Selenium in the Treatment of Arsenic Toxicity and Cancers (SETAC)

Arsenical Melanosis | Arsenical Keratosis | Arsenical Cancers | Arsenicosis | Arsenic Exposure | Arsenic Toxicity | Arsenic Poisoning

Bangladesh
Assiut University

Completed

Supportive Measures in Treatment of Aluminum Phosphide Poisoning

Detection of Different Prognostic Factors and Their Relation With the Outcome | Using New Protocol to Prove the Role of N-acetyl Cysteine and Adequate Supportive Measures in Aluminum Phosphide Poisoning
Charite University, Berlin, Germany

Completed

Modification of Pavlovian and Instrumental Learning in Human Addiction

Healthy | Alcohol Use Disorder (Mild vs. Moderate to Heavy)

Germany
European Institute of Oncology

Recruiting

Myocardial Fibrosis Identification in Patients With Anthracycline-induced Cardiotoxicity

Cardiomyopathy Due to Drug

Italy
National Taiwan University Hospital

Unknown

Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis

Chronic Graft Versus Host Disease | Sjogren Syndrome | Mucous Membrane Pemphigoid | Cicatrizing Conjunctivitis | Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum | Chemical Burn to Eye

Taiwan
Chang Gung Memorial Hospital

Unknown

Clinical Analysis of Safety in Latent Tuberculosis Infection Prophylaxis Treatment

Adverse Reaction to Drug | 3HP

Taiwan
Rambam Health Care Campus

Completed

Evaluation Prospectively the Level of Reduction in Cognitive Functions of Cancer Patients Who Are on Active Oncology Treatments and Use Cannabis. The Second Goal is to Identify High-risk Groups for Cognitive Impairment Due to Cannabis Use.

1- Cancer Patients During Chemotherapy Treatment | 2- Use of Cannabis Comparing to Control Without Cannabis Use

Israel
Johns Hopkins University

Completed

Recovery Housing and Drug Abuse Treatment Outcome

Opiate Addiction | Mental and Behavioral Disorders Due to Use of Cocaine: Harmful Use

United States
Royal College of Anesthesiologists of Thailand
Chulalongkorn University; Khon Kaen University; Ramathibodi Hospital; Prince of... and other collaborators

Completed

The Thai Surgical Intensive Care Study (Thai-SICU Study) (THAI-SICU)

Critical Illness | Complications of Surgical and Medical Care: General Terms | Adverse Reaction to Drug | Sequelae of External Causes of Morbidity and Mortality

Thailand
University of Minnesota
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Completed

Clinical Intervention in Alcohol Use Disorder

Alcohol Use Disorder | Eligible to go Into the MRI Scanner | Short-term Abstinence From Alcohol Use (2 Week Abstinent)

United States
The University of Hong Kong

Enrolling by invitation

Prospective Evaluation on Cognitive Function and Its Associated Genetic Vulnerability in Cannabis Users (SToP-C_PeCoG)

Cannabis Use | Neurocognitive Dysfunction | Genetic Predisposition

Hong Kong
Sarawak General Hospital
Universiti Sains Malaysia; Avantsar Sdn. Bhd.

Recruiting

Efficacy and Safety of Moisturising Cream With or Without Vitamin E and Urea Cream in Palmar-plantar Erythrodysesthesia (ECaPPE)

Palmar-Plantar Erythrodysesthesia | Palmar-Plantar Erythrodysesthesia Due to Cytotoxic Therapy

Malaysia
Ankara Universitesi Teknokent
International Olympic Committee

Completed

Therapy of Toxic Optic Neuropathy Via Combination of Stem Cells With Electromagnetic Stimulation (Magnovision)

Magnetic Field Exposure | Methanol Poisoning | Toxic Optic Neuropathy | Stem Cell Tyrosine Kinase 1 Y842X

Turkey
The University of Hong Kong

Completed

Substance Misuse To Psychosis for Ketamine (SToP-K)

Psychotic Disorders | Schizophrenia | Substance Use Disorders | Genetic Predisposition | Ketamine Abuse

Hong Kong
University of Nebraska
VA Nebraska Western Iowa Health Care System

Completed

Airway Macrophages and Sputum Milieu in Adult Subjects With Airflow Obstruction

Pulmonary Disease, Chronic Obstructive | Occupational Diseases | Tobacco Use Disorder | Bronchitis, Chronic

United States
University of Minnesota
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure

Fetal Alcohol Spectrum Disorders | Prenatal Alcohol Exposure | Fetal Alcohol Syndrome | Partial Fetal Alcohol Syndrome | Alcohol Related Neurodevelopmental Disorder

United States
San Diego State University

Completed

Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders

Fetal Alcohol Spectrum Disorders | Prenatal Alcohol Exposure | Fetal Alcohol Syndrome | Partial Fetal Alcohol Syndrome | Alcohol-related Neurodevelopmental Disorder

United States
Northwestern University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Cancer... and other collaborators

Recruiting

Liver Cirrhosis Network Cohort Study (LCN-C)

Cirrhosis | Cirrhosis, Liver | Cirrhosis Due to Hepatitis B | Cirrhosis Due to Hepatitis C | Cirrhosis Early | Cirrhosis Advanced | Cirrhosis Infectious | Cirrhosis Alcoholic | Cirrhosis, Biliary | Cirrhosis Cryptogenic | Cirrhosis Due to Primary Sclerosing Cholangitis

United States
National Institute of Diabetes and Digestive and...
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Cancer... and other collaborators

Recruiting

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States (LCN RESCU)

Cirrhosis | Cirrhosis, Liver | Cirrhosis Due to Hepatitis B | Cirrhosis Due to Hepatitis C | Cirrhosis Early | Cirrhosis Advanced | Cirrhosis Infectious | Cirrhosis Alcoholic | Cirrhosis, Biliary | Cirrhosis Cryptogenic | Cirrhosis Due to Primary Sclerosing Cholangitis

United States
University of Minnesota
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Stress Reactivity as a Determinant in Co-occurring Alcohol Use and Anxiety Disorder: Diagnosis and Alcohol Use Outcomes

Stress Disorder | Alcohol Use Disorder | Anxiety Disorder/Anxiety State | Hypothalamic Pituitary Adrenal | Drinking to Cope

United States
Sophie JACOB
Institut National de la Santé Et de la Recherche Médicale, France; Institut... and other collaborators

Withdrawn

REBECCA Study (RadiothErapy for BrEast Cancer and CArdiotoxicity) (REBECCA)

Breast Cancer | Toxicity Due to Radiotherapy | Lesion; Cardiac

France
Chang Gung Memorial Hospital

Completed

Oral Thalidomide and Tegafur-uracil to Decrease Hepatocellular Carcinoma Recurrence

Adult Hepatocellular Carcinoma | Recurrent Hepatocellular Carcinoma | Adverse Reaction to Drug | Vascular Endothelial Growth Factor Overexpression

Taiwan
Charite University, Berlin, Germany

Completed

Prospective Observational Pilot-study for the Evaluation of the Nephro- an Neurotoxicity in the Anti-infectious Therapy With Inhalative Colistin Therapy for Patients With Ventilator-associated Pneumonia (VAP) (LOKALE)

Infection Resistant to Multiple Drugs

Germany
Abramson Cancer Center at Penn Medicine

Active, not recruiting

Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuzumab (CCTGuide Pilot)

Heart Failure | Breast Cancer | Cardiomyopathies | Risk Factor, Cardiovascular | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

Breast Cancer | Fatigue | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Long-term Effects Secondary to Cancer Therapy in Adults | Chemotherapeutic Agent Toxicity

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

Brain and Central Nervous System Tumors | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia

Leukemia | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection (NTproBNP-Guide)

Heart Failure | Lymphoma | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
Children's Cancer and Leukaemia Group

Unknown

Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

Infertility | Ovarian Cancer | Sexual Dysfunction | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Gastrointestinal Complications | Urinary Complications | Pulmonary Complications | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Ireland, United Kingdom
Emory University

Terminated

Post-operative Pain Control After Pediatric Adenotonsillectomy

Obstructive Sleep Apnea | Sleep Disordered Breathing | Adverse Reaction to Drug | Recurrent Tonsillitis

United States
Medical University of Warsaw

Recruiting

Possible Differences in HCC Course Depending on DAA Treatment

Liver Cirrhosis | Carcinoma, Hepatocellular | Hepatitis C, Chronic | Drug Effect | Hepatitis C Virus Infection, Response to Therapy of | Drug Side Effect

Poland
Kartal Kosuyolu Yuksek Ihtisas Education and Research...
Trakya University

Completed

The Use of Midazolam and Remifentanil During Dialysis Access Procedures

Chronic Kidney Diseases | Patient Satisfaction | Arteriovenous Fistula | Adverse Reaction to Drug | Analgesic Adverse Reaction | Sedative Adverse Reaction | Midazolam Adverse Reaction
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
University Hospital, Limoges

Recruiting

Acceptability of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users in Non-conventional Structures (SCANVIR)

Hepatitis C | Hepatitis C Virus Infection, Response to Therapy of | Addiction, Alcohol | Addiction Opiate | Transmission, Intravenous Drug Abuser

France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia

Untreated Childhood Acute Lymphoblastic Leukemia | Childhood T Acute Lymphoblastic Leukemia | Neurotoxicity Syndrome | Childhood B Acute Lymphoblastic Leukemia | Cognitive Side Effects of Cancer Therapy | Psychological Impact of Cancer | Long-Term Effects Secondary to Cancer Therapy in Children

United States, Canada, Australia, New Zealand
Children's Cancer and Leukaemia Group

Active, not recruiting

Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy

Brain and Central Nervous System Tumors | Ototoxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children

United Kingdom
Brigham and Women's Hospital
Northeastern University

Completed

Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered (PSLL)

Venous Thromboembolism | Patient Fall | Adverse Drug Event | Severe Hypoglycemia | Hospital Acquired Pressure Ulcer | Central Line-Associated Bloodstream Infection (CLABSI) | Catheter-Associated Infection | Opioid-Related Severe Adverse Drug Event | Severe Hospital Acquired Delerium | Rapid Response Related...

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
OMNI Medical Services, LLC
OMNI Medical Services Inc

Recruiting

Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

Depression | COVID-19 | Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Covid19 | Chronic Pain | Parkinson Disease | Inflammatory Bowel Diseases | Hepatitis C | Insomnia | HIV/AIDS | Amyotrophic Lateral Sclerosis | Fibromyalgia | Anxiety | Bipolar Disorder | Seizures | Crohn Disease | Traumatic Brain Injury | Ulcerative Colitis | Sickle... and other conditions

United States

Clinical Trials on Exposure to Chemical Pollution, Occupational

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Romania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations