Clinical Trials on Eye Infections, Fungal

Total 70065 results

Merck Sharp & Dohme LLC
JSS Medical Research Inc.

Completed

A Study to Examine the Efficacy and Safety of Posaconazole When Introduced Early in the Treatment of Refractory Fungal Infections (P05090 AM2) (TIP)

Mycoses
Pfizer

Withdrawn

Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects

Aspergillosis | Invasive Pulmonary Aspergillosis | Neuroaspergillosis
Seoul National University Hospital
Merck Sharp & Dohme LLC

Completed

Posaconazole Prophylaxis During ATG Treatment for hMDS/AA Patients

Myelodysplastic Syndromes | Fungal Infection | Aplastic Anemia

Korea, Republic of
Dongkook Pharmaceutical Co., Ltd.

Completed

Pharmacokinetics and Safety of AmBisome and DKF-5122

Invasive Fungal Infections | Neutropenic Fever

Korea, Republic of
Michigan State University

Recruiting

Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?

Sepsis | Systemic Inflammatory Response Syndrome | Infection, Bacterial | Infection, Coronavirus | Infection, Fungal | Infection Mixed

United States
Vanderbilt University Medical Center

Completed

Can COVID-19 Persist in Intraocular Fluid?

Ocular Infection, Viral

United States
Laboratoires Thea

Completed

Study of the Ocular Safety After Repeated Instillations of T1225 1% or 1.5% Eye Drops in Healthy Volunteers

Eye Infections, Bacterial
Laboratoires Thea

Completed

Ocular Pharmacokinetics After a Single Drop Instillation of T1225 0.5, 1, 1.5% in 91 Healthy Volunteers

Eye Infections, Bacterial
University of Miami

Recruiting

Comparison of Conjunctival Antimicrobial Activity and Patient Comfort Between Topical Hypochlorous Acid (Avenova) and Betadine

Eye Infections, Bacterial

United States
Laboratoires Thea

Completed

Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1 and 1.5% in 48 Healthy Volunteers

Eye Infections, Bacterial

France
Pfizer

Terminated

An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida

Candidiasis | Fungemia

Belgium, United States, Canada, Switzerland, Netherlands, Bulgaria, Portugal, Romania, Russian Federation
Ziv Hospital

Unknown

The Influence of Hospital Environment on Eyes Infections in Medical Staff

Eye Infections

Israel
National Institute of Allergy and Infectious Diseases...

Completed

Dexamethasone in Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States, Puerto Rico
InterMune

Completed

Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States, Peru
Pfizer

Completed

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

Pilot Study of Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Matinas BioPharma Nanotechnologies, Inc.
University of Minnesota

Not yet recruiting

Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial 3 (EnACT3)

Cryptococcal Meningitis
Makerere University
Gilead Sciences; University of Minnesota

Recruiting

Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia (ACACIA)

Cryptococcal Meningitis

Uganda
Matinas BioPharma Nanotechnologies, Inc.
University of Minnesota

Completed

Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT) (EnACT)

Cryptococcal Meningitis

Uganda
TTY Biopharm

Unknown

Liposomal Amphotericin B for the Treatment of Cryptococcal Meningitis

Cryptococcal Meningitis

Taiwan
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS

Cryptococcal Meningitis

South Africa
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS

Cryptococcal Meningitis

United States
Tan Tock Seng Hospital
Mayo Clinic

Unknown

Impact of Rapid Pathogen Identification From Blood Cultures (RABbIT) (RABbIT)

Sepsis | Fungemia | Bacteremia | Blood Stream Infection

Singapore
Laboratoires Thea

Completed

Ocular Tolerance, Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1.0, 1.5% in 48 Healthy Volunteers

Eye Infections, Bacterial
Taro Pharmaceuticals USA

Completed

Safety and Efficacy of NVXT Solution in Mild-to-Moderate Fungal Infection of the Toe Nail

Onychomycosis
European Organisation for Research and Treatment...

Completed

Empirical Versus Preemptive Antifungal Therapy

Myelodysplastic Syndromes | Leukemia | Fungal Infection

Belgium, Netherlands, Germany, France, Czechia, Slovakia
National Cancer Institute (NCI)

Completed

Voriconazole With or Without Interferon Gamma in Treating Patients With Aspergillosis or Other Fungal Infections

Unspecified Adult Solid Tumor, Protocol Specific | Infection

United States
Services Institute of Medical Sciences, Pakistan

Completed

Efficacy of Prophylactic Fluconazole Therapy in Preterm and Very Low Birth Weight Neonates in Preventing Invasive Fungal Infection.

Invasive Candidiases

Pakistan
University Hospital, Montpellier

Completed

Granulomatous Pneumocystis Pneumonia (NC)

Invasive Fungal Infections | Pulmonary Nodule | Pneumocystis Jirovecii

France
Scynexis, Inc.

Completed

ADME Study of [14^C]-Ibrexafungerp in Healthy Male Subjects

Fungal Disease

United Kingdom
Deacon Biosciences, Inc.
ORA, Inc.

Completed

A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers

Ocular Infection

United States
Radboud University Medical Center

Completed

Pharmacokinetics of Fluconazole IV as Prophylaxis or Therapy to ICU Patients (PACIFIC)

Candidiasis

Netherlands
Merck Sharp & Dohme LLC

Completed

Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101)

Aspergillosis
National Institute of Allergy and Infectious Diseases...
Washington University School of Medicine

Completed

A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States, Canada
Invirsa, Inc.
Biomedical Advanced Research and Development Authority

Recruiting

Study of INV-102 Ophthalmic Solution in Adults With Acute Infectious Keratoconjunctivitis

Acute Infectious Keratoconjunctivitis

United States, Thailand
University of Zimbabwe
AIDS Care Research in Africa

Completed

Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa

HIV Infections | Cryptococcal Meningitis

Zimbabwe
Botswana-UPenn Partnership
University of Pennsylvania; Doris Duke Charitable Foundation

Completed

Optimal Time to Start Antiretroviral Therapy in HIV-infected Adults With Cryptococcal Meningitis (Crypto)

HIV Infections | Cryptococcal Meningitis

Botswana
National Cancer Institute (NCI)

Completed

Voriconazole to Treat Fungal Infections

Mycoses

United States
ANRS, Emerging Infectious Diseases
St George's, University of London; Yaounde Central Hospital

Unknown

Pre-Antiretroviral Therapy (ART) Cryptococcal Antigen Screening in AIDS (PreCASA)

Cryptococcal Meningitis

Cameroon
National Institute of Allergy and Infectious Diseases...

Completed

Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States, Canada
National Institute of Allergy and Infectious Diseases...
Schering-Plough

Completed

SCH 39304 as Therapy for Acute Cryptococcal Meningitis in HIV-Infected Patients Followed by Maintenance Therapy

HIV Infections | Meningitis, Cryptococcal

United States
University of Pharmacy, Yangon

Completed

Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal Meningitis

Cryptococcal Meningitis

Myanmar
University of Zimbabwe
Centers for Disease Control and Prevention

Completed

CryptoART Study: Decreasing Mortality Associated With Initiation of Antiretroviral Therapy in Sub-Saharan Africa (CryptoART)

Cryptococcal Meningitis

Zimbabwe
National Hospital for Tropical Diseases, Hanoi,...

Completed

Vietnam Cryptococcal Retention in Care Study (CRICS) Federal Financial Report

Cryptococcal Meningitis

Vietnam

3

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