Clinical Trials on First-line Treatment

Total 7619 results

Shriners Hospitals for Children

Completed

Use of a Diurnal Indwelling Urethral Catheter to Improve Quality of Life

Neurogenic Bladder | Spina Bifida
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Health-related Quality of Life and Fatigue in Adult Patients With Primary Immune Thrombocytopenic Purpura (pITP)

Immune Thrombocytopenic Purpura

Italy
Tampa General Hospital

Terminated

Quality of Life and Nutritional Improvements in Cirrhotic Patients

Liver Cirrhosis | Hepatic Encephalopathy | Portal Hypertension

United States
AstraZeneca

Completed

Quality of Life Validation in Laryngitis

Laryngopharyngeal Reflux (LPR)
Brown University
Taiho Oncology, Inc.

Recruiting

TAS-116 Plus Palbociclib in Breast and Rb-null Cancer

Soft Tissue Sarcoma | Advanced Breast Cancer | SCLC | Bladder Cancer | Endometrial Cancer | Treatment-Refractory Solid Tumors | Retinoblastoma Deficiency

United States
Kahramanmaras Sutcu Imam University

Not yet recruiting

Evaluation of Biopsychosocial Features, Pain, Fatigue, Quality of Life, Swallowing, and Disease-Specific Symptoms in Patients With Primer Sjogren's Syndrome

Sjogren's Syndrome

Turkey
University of British Columbia
Stanford University; University of Victoria; St. Paul's Hospital, Canada; Providence... and other collaborators

Recruiting

Postpartum Screening for Anxiety and Comorbid Conditions (PPA)

Anger | Quality of Life | Sleep Wake Disorders | Postoperative Pain | Postpartum Depression | Postpartum Disorder | Postpartum Anxiety

Canada
Lithuanian University of Health Sciences

Recruiting

Respiratory and Cardiovascular Alterations in Patients With Chronic Obstructive Pulmonary Disease

Cardiovascular Diseases | Quality of Life | Chronic Obstructive Pulmonary Disease Moderate | Chronic Obstructive Pulmonary Disease Severe

Lithuania
Koç University

Not yet recruiting

To Use the Combined Version of ICIQ-SF and Quality of Life Scale in Mixed Urinary Incontinence

Quality of Life | Incontinence, Urge | Incontinence Stress
Ondokuz Mayıs University

Not yet recruiting

The Effect of Incontinence Program Applied to Obese Elderly on Quality of Life, Coping and Loneliness

Aging | Incontinence, Urge | Incontinence Stress | Obesity, Primary

Turkey
Buddhist Tzu Chi General Hospital
Ministry of Science and Technology, Taiwan; Hualien Tzu Chi General Hospital

Recruiting

Using Oral Valacyclovir to Treat Patients With Refractory IC/BPS (VARIC)

Quality of Life | Pain, Chronic | Urge Incontinence | Overactive Bladder Syndrome

Taiwan
Boston Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event (BRUE)

Oropharyngeal Dysphagia | Brief Resolved Unexplained Event | Apparent Life Threatening Event

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pelvic Floor Dysfunction and Quality of Life in Uterine Cancer Survivors

Endometrial Carcinoma | Malignant Uterine Neoplasm | Uterine Corpus Cancer | Uterine Corpus Sarcoma

United States
Universidad Autónoma de Yucatán

Active, not recruiting

Quality of Life and Sexual Life in Hemodialysis Patients: Effects of an Intradialytic Exercise Program

Chronic Kidney Diseases | Sexual Dysfunction

Mexico
National and Kapodistrian University of Athens
Ioulia And Irene Tseti Pharmaceutical Laboratories S.A.

Completed

Assessing the Efficacy of a Hydrogen Peroxide Gel for Oral Wound Healing and Oral Hygiene

Quality of Life | Postoperative Pain | Dental Plaque | Wound Heal | Gingival Inflammation | Biopsy Wound | Wound; Mouth

Greece
Hacettepe University

Completed

The Struggle That Is Phenylketonuria : What Do The Patients and Caregivers Suffer From

Caregiver Burden | Life Stress | Psychological Well-Being

Turkey
University of Turku
Finnish Cultural Foundation

Completed

The Effectiveness of an Online Exercise Program on Well-being of Postpartum Women

Quality of Life | Physical Activity | Urinary Incontinence | Pelvic Organ Prolapse

Finland
UMC Utrecht
Isala

Completed

Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis (PRE-FURTHER)

Quality of Life | Pain | Neoplasm Metastasis | Bone Cancer | Bone Metastases | Tumor | Radiation Toxicity | Bone Neoplasm | Bone Lesion | Cancer Induced Bone Pain

Netherlands
Region of Southern Denmark
University of Southern Denmark; Region Zealand

Active, not recruiting

Patient Reported Outcome After Nephron Sparing Treatment of Small Renal Tumours

Quality of Life | Renal Cell Carcinoma

Denmark
Convexity Scientific Inc
COPD Foundation

Completed

Observational Study of the Wellinks Solution Impact on Quality of Life and Clinical Outcomes in Patients With COPD (ASPIRE)

Chronic Obstructive Pulmonary Disease | COPD | Chronic Obstructive Pulmonary Disease Moderate | Chronic Obstructive Pulmonary Disease Severe

United States
Chiesi SA/NV

Enrolling by invitation

Observational Study to Assess the Quality of Life in Nephropathic Cystinosis Patients (PROREAL)

Nephropathic Cystinosis

Belgium
Suzanne Morin
CHU de Quebec-Universite Laval

Completed

Determinants of Bone and Muscle Quality and Strength in Obesity With and Without Diabetes (BODI2)

Quality of Life | Obesity | Fractures, Bone | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Body Weight | Musculoskeletal Diseases | Osteoporosis | Bone Diseases, Metabolic | Fall | Osteoporotic Fractures

Canada
Astellas Pharma Global Development, Inc.

Approved for marketing

Expanded Access Study of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) or FLT3-Mutated AML in Complete Remission (CR) With Minimal Residual Disease (MRD)

Acute Myeloid Leukemia (AML) | FMS-like Tyrosine Kinase-3 (FLT3) Mutations

United States, Canada, Japan
Hellenic Red Cross Hospital
G.Gennimatas General Hospital

Completed

Quality of Life Assessment Between Stroke and Multiple Sclerosis Patients of the Same Age Range (QoLSMS)

Depression | Stroke | Quality of Life | Multiple Sclerosis | Mental Health Disorder

Greece
University of Nottingham
National Institute for Health Research, United Kingdom; International Stem...

Completed

Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors

Quality of Life | Cancer | Hearing Loss, Sensorineural | Tinnitus, Subjective | Late Effect

United Kingdom
University of Colorado, Denver

Completed

Effects of an Adapted Ski/Snowboarding Program on Quality of Life in Children With Physical Disabilities

Cerebral Palsy | Spinal Cord Injuries | Physical Disability | Traumatic Brain Injuries

United States
Sahlgrenska University Hospital, Sweden

Completed

Effectiveness of Insoles Provided to Patients With Diabetes. A Longitudinal Randomized Controlled Study in Gothenburg

Quality of Life | Diabetic Foot | Neuropathy

Sweden
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Unknown

Quality of Life Associated With a Low-Risk Screening Program for Ovarian Cancer

Ovarian Cancer

United States
Otsuka Pharmaceutical Europe Ltd

Unknown

A Study Measuring Quality of Life, Treatment Preference and Satisfaction of ADPKD Patients in Europe (ACQUIRE)

Autosomal Dominant Polycystic Kidney Disease

Spain, United Kingdom, Germany, France, Belgium, Switzerland, Austria
Stockton University
Nova Southeastern University

Completed

The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency Disease

Common Variable Immunodeficiency | Hypergammaglobulinemia | Primary Immune Deficiency Disorder | Specific Antibody Deficiency

United States
Chelsea and Westminster NHS Foundation Trust
Imperial College London; Imperial College Healthcare NHS Trust; University of...

Completed

PRIME: Cognitive Outcome Following Major Burns (PRIME)

Depression | Quality of Life | Burns | Cognitive Dysfunction | Anxiety | PostTraumatic Stress Disorder | Inflammation, Brain

United Kingdom
University Health Network, Toronto
Novo Nordisk A/S

Withdrawn

Psoriatic Arthritis Treated With Liraglutide Therapy: a QUality of Life and Efficacy Study (PLAQUE)

Psoriasis | Type 2 Diabetes | Impaired Glucose Tolerance | Psoriatic Arthritis

Canada
University of Florida

Completed

Apathy in Tourette Syndrome and Changes in Quality of Life

Tourette Syndrome | Apathy

United States
University of Medicine and Dentistry of New Jersey
National Institute of Nursing Research (NINR)

Completed

Quality of Life in Children With HIV Infection

HIV Infections

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Printed Education Materials in Patients Who Are Finishing Treatment for Stage I, Stage II, or Stage IIIA Breast Cancer, Colorectal Cancer, Prostate Cancer, or Chest Cancer

Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Malignant Mesothelioma | Psychosocial Effects of Cancer and Its Treatment | Thymoma and Thymic Carcinoma

United States
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

CAPABLE Transplant

Depression | Quality of Life | End Stage Renal Disease | Disability Physical

United States
Universitas Muhammadiyah Yogyakarta
Ministry of Education Culture, Research and Technology

Not yet recruiting

Development of Health Monitoring System on Patient's Well Being in Dialysis Context (SIKIDI)

Quality of Life | Chronic Kidney Diseases | Self Efficacy | M-health

Indonesia
M.D. Anderson Cancer Center
Janssen Scientific Affairs, LLC

Not yet recruiting

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

Prostate Cancer | Prostatectomy | Androgen Axis Suppression

United States
Ostfold Hospital Trust

Not yet recruiting

The Norwegian World Health Organisation Labour Care Guide Trial (NORWEL) (NORWEL)

Progression | Cesarean Section Complications | Labor Complication | Labor Onset and Length Abnormalities | Experience, Life | Labor (Obstetrics)--Complications | Labor Dystocia | Apgar; 4-7 at 1 Minute

Norway
Hospital Clínico Universitario de Valladolid
Red Centinela Sanitaria de Castilla y León (RCSCYL); Centro Nacional de Gripe... and other collaborators

Recruiting

InfluenCEF Study: Study on the Headache Associated With Influenza Infection (INFLUENCEF)

Migraine | Headache Disorders | Viral Infection | Influenza -Like Illness | Head Pain

Spain
RefleXion Medical

Recruiting

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System (PREMIER)

Cancer | Cancer, Gastrointestinal | Cancer Central Nervous System | Cancer Thoracic | Cancer Gynecologic | Cancer, Genito-Urinary | Cancers Lymphatic | Cancer Head and Neck

United States
National Taiwan University Hospital

Not yet recruiting

The Effect of Interventional Pulmonary Rehabilitation Exercise With Advanced Lung Cancer.

Quality of Life | Lung Neoplasms | Lung Cancer | Exercise | Lung Adenocarcinoma | Psychological Distress | Pulmonary Rehabilitation | Self Efficacy | Advanced Lung Cancer | Lung Tumor
St. Louis University

Recruiting

Mindfulness in Endometrial and Cervical Cancer (MECCA)

Quality of Life | Cervical Cancer | Gynecologic Cancer | Endometrial Cancer | Opioid Use

United States
Erasmus Medical Center
Baxter Healthcare Corporation

Recruiting

The Effect of Intradialytic Parenteral Nutrition on Nutritional Status and Quality of Life in Hemodialysis Patients

Malnutrition | End Stage Renal Disease | Hemodialysis Complication | Sarcopenia

Netherlands
London School of Hygiene and Tropical Medicine
University of Oxford

Completed

Health-related Quality of Life and Long COVID (OpenPROMPT)

Long COVID

United Kingdom
University Hospital of North Norway
Helse Nord

Withdrawn

Effects of Structured Rehabilitation Program on Quality of Life in Rectal Cancer Patients- a Randomized Controlled Trial

Quality of Life | Urinary Incontinence | Anal Incontinence | Sexual Function

Norway
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Health Related Quality of Life and Cognitive Function Among Norwegian Dialysis Patients

Renal Dialysis | Chronic Kidney Failure

Norway
Kenneth Rockwood
Nova Scotia Health Authority; Research Nova Scotia; Department of Health, Nova...

Enrolling by invitation

Far-UVC Light Devices in Long-term Care Facilities to Reduce Infections (UVCinLTCs)

COVID-19 Respiratory Infection | Influenza -Like Illness | Respiratory Virus Infection

Canada
Second Affiliated Hospital, School of Medicine,...

Completed

Clinical Characteristics, Treatment and Prognosis of Chest Tightness Variant Asthma

Quality of Life | Asthma | Eosinophilia | Nitric Oxide | Airway Responsiveness | Clinical Depression | Chest Syndrome | Lung Function | Clinical Anxiety | Induced Sputum

China
Zhebao Wu
The First Affiliated Hospital of Nanchang University; Shanghai Zhongshan Hospital and other collaborators

Unknown

The Impact of Endoscopic Pituitary Surgery on Nasal Function

Quality of Life | Pituitary Tumor | Endoscopic Surgery | Function of Nose

China

Clinical Trials on First-line Treatment

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