Clinical Trials on Fluid Overload in Canada

Total 47 results

Nova Scotia Health Authority

Not yet recruiting

Effect of High-Flow Nasal Cannula on IVC Measurements Using Point of Care Ultrasound

Fluid Overload

Canada
University of Alberta

Completed

Target Weight Correction and Vascular Stiffness in Hemodialysis Patients

Fluid Overload | Vascular Stiffness

Canada
Hamilton Health Sciences Corporation
McMaster University

Withdrawn

Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery (RAPPER-MAN)

Coronary Artery Disease | Fluid Overload | Hemodilution

Canada
Centre hospitalier de l'Université de Montréal...
Sunnybrook Health Sciences Centre; University of Alberta; Unity Health Toronto; University of Kentucky and other collaborators

Completed

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury (ECHO-AKI)

Acute Kidney Injury | Ultrasonography | Fluid Overload

Canada, United States
Unity Health Toronto
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Role of Active Deresuscitation After Resuscitation: (RADAR-Canada)

Sepsis | Critical Illness | Trauma | ARDS | Fluid Overload

Canada
Clinical Evaluation Research Unit at Kingston General...

Completed

Phosphate Bioavailability Hormonal Response to a Breakfast Meal in Healthy Humans

Phosphate Overload

Canada
University Health Network, Toronto

Completed

Advanced Monitoring to Inform and Guide Perioperative Hemodynamic Optimization 1 (AMIGO-1) Study (AMIGO-1)

Intraoperative Fluid Management

Canada
Sunnybrook Health Sciences Centre
University Health Network, Toronto; Canadian Blood Services

Completed

Transfusion-Associated Circulatory Overload Best Eliminated With Lasix

Transfusion-associated Circulatory Overload

Canada
University of Calgary
Department of Critical Care Medicine

Completed

Internal Jugular Vein Ultrasound Measures and Fluid Responsiveness in Post-Operative Cardiac Surgical Patients

Fluid Therapy | Cardiac Surgical Procedures

Canada
Hamilton Health Sciences Corporation
Firestone Institute for Respiratory Health

Completed

Nasal Lavage Study: Comparing Single Versus Multi Sample Lavages

Nasal Lavage Fluid | Eosinophils | Reproducibility of Results

Canada
Montreal Heart Institute

Completed

Evaluation of the E/e' Ratio of the Mitral Annulus in Predicting Fluid Responsiveness.

Left Ventricular Function Diastolic Dysfunction | Fluid Responsiveness

Canada
McMaster Children's Hospital

Completed

Pediatric Fast Fluid Randomized Controlled Trial

Fluid Resuscitation

Canada
Ottawa Hospital Research Institute

Completed

Crystalloid FLUID Choices for Resuscitation of Hospital Patients (FLUID)

Fluid Therapy

Canada
Ottawa Hospital Research Institute

Completed

Crystalloid FLUID Choices for Resuscitation of Hospitalized Patients (FLUID)

Fluid Therapy

Canada
Andrea Kew

Completed

Safety and Efficacy of Iron Reduction by Phlebotomy

Iron Overload

Canada
ApoPharma

Completed

Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload (TWICE)

Iron Overload Due to Repeated Red Blood Cell Transfusions

United States, Canada, Greece, Italy
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Deferasirox in Combination With Deferoxamine Followed by Deferasirox Monotherapy in Severe Cardiac Iron Overload (HYPERION)

Cardiac Iron Overload

Taiwan, Egypt, Thailand, Turkey, United Kingdom, Italy, Canada, Greece
Shire

Terminated

Study for Transfusionally Iron Overloaded Children, Adolescents and Adults Using FBS0701 (SSP-004184)

Iron Overload Due to Repeated Red Blood Cell Transfusions

Canada, United States, Thailand, Italy, United Kingdom
McMaster Children's Hospital
Regional Medical Associates of Hamilton

Completed

Pediatric Fast Fluid Trial 2 (PFFT2)

Shock | Fluid Therapy | Pediatrics | Resuscitation

Canada
Shire

Terminated

Pharmacokinetics of SSP-004184 in the Treatment of Chronic Iron Overload Requiring Chelation Therapy

Iron Overload Due to Repeated Red Blood Cell Transfusions

United States, Canada, Lebanon, Italy, Egypt
Centre hospitalier de l'Université de Montréal...
The Kidney Foundation of Canada

Recruiting

Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy (TECHNO-HDF)

Acute Kidney Injury | Fluid Overload | Chronic Kidney Failure | Intradialytic Hypotension | Chronic Kidney Disease Stage 5 on Dialysis

Canada
Maisonneuve-Rosemont Hospital
Université de Montréal

Unknown

ED50 Determination of Hydroxyethylstarch for Treatment of Hypotension During Cesarean Section Under Spinal Anesthesia

Hypotension | Cesarean Section | Spinal Anesthesia | Fluid Therapy | Obstetric Anesthesia

Canada
University Health Network, Toronto

Completed

MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias (MAFIO)

Thalassemia Major | Chronic Blood Transfusion Related Iron Overload

Canada
Cook Research Incorporated

Completed

Post-market Assessment of Biodesign Dural Repair Grafts

Cerebrospinal Fluid Leak

Canada, United States, Italy
Shire

Terminated

Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload

Beta-Thalassemia | Transfusional Iron Overload

United States, Lebanon, Canada, Italy, Turkey
Novartis Pharmaceuticals

Completed

Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload (CORDELIA)

Transfusional Hemosiderosis | Transfusional Iron Overload

Taiwan, Turkey, Egypt, United Kingdom, Thailand, Canada, China, Italy, Cyprus, Lebanon, United Arab Emirates
Novartis Pharmaceuticals

Completed

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Transfusion-dependent Anemia

Egypt, Hungary, Turkey, United States, Bulgaria, Italy, Belgium, Russian Federation, Philippines, France, Malaysia, India, Oman, Panama, Lebanon, Thailand, Tunisia
Kevin H.M. Kuo, MD, MSc, FRCPC

Unknown

Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients (CANALI)

Iron Overload | Beta-Thalassemia

Canada
Novartis Pharmaceuticals

Completed

An Extension Study of Iron Chelation Therapy With Deferasirox (ICL670) in β-thalassemia Patients With Transfusional Iron Overload

Transfusional Iron Overload in β-thalassemia

United States, Greece, Argentina, Germany, Belgium, Italy, United Kingdom, France, Tunisia, Canada, Turkey, Brazil
University Health Network, Toronto

Recruiting

Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation (TICATS)

Thalassemia Major

Canada
Abfero Pharmaceuticals, Inc

Withdrawn

SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias

Iron Overload | Beta-Thalassemia

Thailand, Lebanon, Turkey, Canada
Ethicon, Inc.

Completed

The EVICEL® Neurosurgery Phase III Study

Cerebrospinal Fluid Leak

United States, Australia, Belgium, Canada, New Zealand, United Kingdom
Protagonist Therapeutics, Inc.

Completed

PTG-300 in Subjects With Hereditary Hemochromatosis

Hereditary Hemochromatosis

United States, Canada
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subject With Euvolemic Hyponatremia

Hyponatremia With Normal Extracellular Fluid Volume

United States, Canada, Germany, India, Poland, Belgium
Sideris Pharmaceuticals

Terminated

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Iron Overload | Beta-Thalassemia

United States, Canada, Lebanon, Thailand, Turkey
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Deferasirox (ICL670) in Patients With Iron Overload Resulting From Hereditary Hemochromatosis

Iron Overload | Hereditary Hemochromatosis

United States, Germany, Italy, Australia, Canada, France
Novartis Pharmaceuticals

Terminated

Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)

Hereditary Hemochromatosis

Belgium, France, Russian Federation, Romania, Slovakia, Spain, Switzerland
Novartis Pharmaceuticals

Completed

Study of Deferasirox for Treatment of Transfusional Iron Overload in Myelodysplastic Patients

Iron Overload | Myelodysplastic Syndrome

United States, Canada
ApoPharma

Terminated

Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias

Iron Overload | Sickle Cell Disease | Other Anemias

United States, United Kingdom, Egypt, Canada, Saudi Arabia
University Health Network, Toronto

Recruiting

Canadian Network for Autoimmune Liver Disease (CaNAL)

Autoimmune Hepatitis | Primary Bilary Cirrhosis (PBC) | Overlap Syndrome

Canada
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); Thalassemia Clinical Research...

Completed

Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)

Hematologic Diseases | Iron Overload | Hypertension, Pulmonary | Osteoporosis | Thalassemia | Beta-Thalassemia | Anemia, Cooley's

United States, Canada
ApoPharma

Terminated

Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias (FIRST)

Iron Overload | Sickle Cell Disease | Other Anemias

United States, Turkey, United Kingdom, Egypt, Saudi Arabia, Brazil, Canada, Tunisia
Paul R Fortin
Canadian Institutes of Health Research (CIHR)

Recruiting

COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases (COVBIRD)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Systemic Vasculitis | Immunosuppression | Scleroderma | Autoimmune Rheumatologic Disease | Undifferentiated Connective Tissue Diseases | Overlap Connective Tissue Disease

Canada
Novartis Pharmaceuticals

Completed

Extension Study of Iron Chelation Therapy With Deferasirox in β-thalassemia and Rare Chronic Anemia Patients

Anemia | Hemosiderosis

United States, Germany, Belgium, United Kingdom, Italy, Canada, France
Novartis Pharmaceuticals

Completed

Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients

Iron Overload | Sickle Cell Disease | Hemolytic Anemia

United States, Canada
Novartis Pharmaceuticals

Completed

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Myelofibrosis | Sickle Cell Disease | Thalassemia | Diamond Blackfan Anemia

United States, Netherlands, Taiwan, Thailand, Italy, Germany, Spain, Canada, Belgium, Greece, Turkey, United Kingdom
Incyte Corporation

Recruiting

Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms (LIMBER)

Myelofibrosis | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome | Relapsed or Refractory Primary Myelofibrosis | Secondary Myelofibrosis (Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis) | ET...

United States, Spain, Japan, Italy, Finland, United Kingdom, Canada

Clinical Trials on Fluid Overload in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bulgaria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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