Clinical Trials on Focal Onset Epilepsy in Australia

Total 169 results

Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
Neurocrine Biosciences

Completed

A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Belgium, Czechia, France, Italy, Australia, Hungary, United Kingdom
UCB Biopharma S.P.R.L.

Completed

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy (ARISE)

Focal-Onset Seizures | Drug-resistant Epilepsy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Lithuania, Mexico, Poland, Portugal, Slovakia, Spain, Turkey, United Kingdom
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
Cerebral Therapeutics LLC

Terminated

Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps for CSF Infusion

Focal Epilepsy

Israel, Australia
Cerebral Therapeutics LLC

Terminated

Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

Refractory Epilepsy

Israel, Australia
UCB Pharma GmbH

Completed

Study Evaluating Changes in Total Drug Load and Seizure Frequency Using Vimpat® (Lacosamide) in Combination Therapy (VICTOS)

Focal Epilepsy With and Without Secondary Generalization

Germany, Austria
NYU Langone Health
The Epilepsy Study Consortium

Completed

The Human Epilepsy Project (HEP)

Focal Epilepsy

United States, Canada, Australia
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

Focal Onset Seizures

United States, Spain, Italy, Croatia, Portugal, Poland, Chile, Argentina, Austria, Czechia
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE2)

Focal Onset Seizures

United States, Spain, Australia, Poland, Canada, Bulgaria, Italy, United Kingdom
Genovate-NaviFUS (Australia) Pty Ltd.
Genovate Biotechnology Co., Ltd.,; NaviFUS Corporation

Recruiting

Evaluation of the NaviFUS System in Drug Resistant Epilepsy

Drug Resistant Epilepsy | Epilepsy, Temporal Lobe

Australia
Supernus Pharmaceuticals, Inc.
Melbourne Health

Completed

Bioavailability, Safety, and Tolerability of BIS-001 ER

Epilepsy, Complex Partial

Australia
Supernus Pharmaceuticals, Inc.

Active, not recruiting

BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures (FIAS)

Focal Impaired Awareness Seizures

Australia
ES Therapeutics Australia Pty Ltd

Recruiting

Efficacy, Safety and Pharmacokinetics of ES-481 in Adult Patients With Drug Resistant Epilepsy

Drug Resistant Epilepsy

Australia
Dimerix Bioscience Pty Ltd
Iqvia Pty Ltd

Completed

Safety and Effectiveness of Propagermanium in Focal Segmental Glomerulosclerosis Participants Receiving Irbesartan (ACTION)

Focal Segmental Glomerulosclerosis

Australia
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Dravet Syndrome

Australia
Duke University
Christian Doppler University Hospital

Enrolling by invitation

5-SENSE Score Validation Study

Epilepsy Intractable

United States, Spain, Australia, Austria, Canada, Czechia, Denmark, France, Germany, Japan, Romania, Switzerland
Syneos Health
AprilBio Co., Ltd.

Completed

Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of APB-R3

Still's Disease, Adult-Onset

Australia
St Vincent's Hospital Melbourne
University of Melbourne; Seer Medical

Completed

Validation of a Seizure Monitoring System

Epilepsy

Australia
Seer Medical Pty Ltd

Enrolling by invitation

Development of a Minimally Invasive Seizure Gauge

Epilepsy

Australia
Xenon Pharmaceuticals Inc.

Terminated

An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE (EPIK-OLE)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Epilepsy | Epileptic Syndromes | Disease | Epilepsy; Seizure | Epilepsy in Children

United States, Australia, Belgium
Noema Pharma AG

Completed

A 10-week Efficacy Study of NOE-105 in Childhood Onset Fluency Disorder (Orpheus)

Childhood-Onset Fluency Disorder

United States, Australia
Sydney Children's Hospitals Network

Unknown

Non-operative Management for Appendicitis in Children (APRES)

Appendicitis | Acute Focal Appendicitis

Australia
Paracelsus Medical University
Heinrich-Heine University, Duesseldorf; Poznan University of Medical Sciences; University Hospital of Ferrara and other collaborators

Completed

Intra-Operative Electron Boost and Hypofractionated Whole-Breast Irradiation During Breast-conserving Treatment (BCT) (HIOB)

Toxicity | Local Neoplasm Recurrence

Austria
Supernus Pharmaceuticals, Inc.

Recruiting

Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy

Epilepsy | Seizures, Epileptic

Australia
NYU Langone Health

Recruiting

Human Epilepsy Project 3 (HEP3)

Idiopathic Generalized Epilepsy

United States, Australia
St Vincent's Hospital Melbourne
University of Melbourne

Completed

A Deep Brain Stimulation System in Epilepsy: Tracking Neural Excitability

Epilepsy | Nodular Heterotopia

Australia
University of Minnesota

Recruiting

Microelectrode Recordings From the Vagus Nerve in Awake Humans

Epilepsy

United States, Australia
Cerebral Therapeutics LLC
Neuroscience Trials Australia

Completed

A Dose Ranging Pilot Study for Intracerebroventricular (ICV) Delivery of Valproate in Subjects With Temporal Seizures

Epilepsy

Australia
NeuroVista Corporation

Terminated

Seizure Advisory System Feasibility Study

Epilepsy

Australia
Mallinckrodt ARD LLC

Completed

Acthar for Treatment-Resistant or Treatment-Intolerant Proteinuria (PODOCYTE)

Idiopathic Focal Segmental Glomerulosclerosis

United States, Argentina, Turkey, Peru, Australia, Chile, Mexico
Bright Minds Biosciences Pty Ltd

Not yet recruiting

BMB-101 in Epilepsy With Eyelid Myoclonia (EEM)

Jeavons Syndrome

Australia
Karl Landsteiner Institute for Clinical Epilepsy...
AIT Austrian Institute of Technology GmbH; Brainhero GmbH

Recruiting

DigitalEPI - A Prospective Pilot Study

Epilepsy

Austria
Medical University of Vienna

Completed

Do Prostheses of SphinkeeperTM Migrate After Operation?

Fecal Incontinence

Austria
Christoph Aufricht

Recruiting

ARREST-NEPHROSIS - Austrian Resistant Nephrotic Syndrome Treatment Response Registry and Biobank

Proteinuria | Focal Segmental Glomerulosclerosis | Nephrotic Syndrome | Nephrotic Syndrome Steroid-Resistant

Austria
Cerecin

Active, not recruiting

Tricaprilin Infantile Spasms Pilot Study

Infantile Spasm

Singapore, Australia
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy (EXPAND)

Childhood Absence Epilepsy | Juvenile Absence Epilepsy

United States, Australia, Georgia, Italy, Poland, Romania, Slovakia, Spain, Ukraine, Belgium
UCB Pharma

Terminated

Hormonal and Lipid Levels in Male Subjects After a Switch From Carbamazepine to Lacosamide (VICTOR)

Epilepsy, Partial

Austria, Germany, Spain
ElectroCore INC

Terminated

Neurostimulation to the Vagus Nerve for the Reduction in Frequency of Seizures Associated With Epilepsy

Seizure

Australia
Sándor Beniczky
Hospital del Mar; Centro Hospitalar e Universitário de Coimbra, E.P.E.; Motol... and other collaborators

Active, not recruiting

Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation (PROMAESIS)

Surgery | Refractory Epilepsy | Electroencephalography | Brain Imaging

Spain, Portugal, Austria, Czechia, Denmark, Germany, Italy, Romania
St Vincent's Hospital Melbourne
Monash University; The Queen Elizabeth Hospital; The University of Queensland; BiomeBank...

Recruiting

Microbial Restoration in Inflammatory Bowel Diseases (MIRO II)

Inflammatory Bowel Diseases | Crohn Disease | Microbiome | Fecal Microbiota Transplantation

Australia
Centrexion Therapeutics

Terminated

Study to Evaluate the Safety and Pharmacokinetics of Topically Applied 40% Lidocaine Gel Compared With Placebo in Subjects With Acute Herpes Zoster (Shingles) Pain

Acute-onset Herpes Zoster Pain

Australia
Great Ormond Street Hospital for Children NHS Foundation...
The Hospital for Sick Children; Boston Children's Hospital; Murdoch Childrens...

Recruiting

Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services (Gene-STEPS)

Epilepsy

United States, Canada, Australia, United Kingdom
MedtronicNeuro

Completed

Product Surveillance Registry- Deep Brain Stimulation for Epilepsy (MORE)

Refractory Epilepsy

Belgium, Sweden, Austria, United Kingdom, Poland, Germany, Portugal, Canada, Finland, Hungary, Italy, Netherlands, Russian Federation
Medical University of Vienna

Completed

SphinkeeperTM Procedure for Treating Severe Faecal Incontinence

Faecal Incontinence

Austria
Medical University of Vienna

Terminated

Improving Secretion of Insulin in New Onset Diabetes After Renal Transplantation (ISINODAT)

New Onset Diabetes Mellitus After Renal Transplantation

Austria
Xenon Pharmaceuticals Inc.

Terminated

XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy (EPIK)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Epilepsy | Epileptic Syndromes | Disease | Epilepsy; Seizure | Epilepsy in Children

United States, Spain, Australia, Belgium, Italy
APrevent Biotech GmbH

Completed

APrevent Vocal Implant System (VOIS) for Adjustable Treatment of Unilateral Vocal Fold Paralysis (UVFP)

Paralysis, Unilateral, Vocal Cord

Austria
LivaNova

Active, not recruiting

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System. (CORE-VNS)

Epilepsy | Seizures | Drug Resistant Epilepsy

Australia, Italy, United States, Israel, United Kingdom, Canada, Brazil, Japan, Belgium, India, Austria, China, Netherlands, Poland, Portugal, Saudi Arabia

Clinical Trials on Focal Onset Epilepsy in Australia

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