Clinical Trials on Fragile X Syndrome

Total 35132 results

Universidad Santo Tomas
Emory University; Universidad Pública de Navarra; Universidad de Granada; University... and other collaborators

Completed

Exercise Training and Hepatic Metabolism in Overweight/Obese Adolescent (HEPAFIT)

Obesity | Lipid Metabolism Disorders | Mental Health Wellness 1 | Body Composition, Beneficial | Metabolic Syndrome X
University of Southern Denmark
The Danish Medical Research Council; National Board of Health, Denmark; Ministry... and other collaborators

Unknown

Evaluation of Effect of Exercise on Prescription

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Metabolic Syndrome X

Denmark
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI); Singulex

Completed

Atheroma Reduction With Chloroquine in Patients With the Metabolic Syndrome (ARCH-MS) (ARCH-MS)

Hypertension | Overweight | Dyslipidemias | Prediabetic State | Metabolic Syndrome X

United States
Uskudar University

Recruiting

Physiotherapy Assessment Based on the ICF Model in The Lesch-Nyhan Syndrome: Case Report

Lesch-Nyhan Syndrome

Turkey
Shire

Completed

Study of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Participants Who Have Completed Study HGT-HIT-094

Hunter Syndrome

United States, Spain, Canada, United Kingdom, Mexico, Australia, France
Green Cross Corporation

Completed

A Study of GC1111 in Hunter Syndrom Patients

Hunter Syndrome

Korea, Republic of
Shire

Completed

Screening Study to Identify Pediatric Patients With Hunter Syndrome Who Demonstrate Evidence of Central Nervous System (CNS) Involvement and Who Are Currently Receiving Treatment With Elaprase®

Hunter Syndrome

United States, United Kingdom
Green Cross Corporation

Unknown

The Long-term Safety Study of Idursulfase-beta in Hunter Syndrome(Mucopolysaccharidosis II) Patients

Hunter Syndrome

Korea, Republic of
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS) (ARCH-MS)

Hypertension | Overweight | Dyslipidemias | Prediabetic State | Metabolic Syndrome X

United States
Retina Foundation of the Southwest
DSM Nutritional Products, Inc.; Foundation Fighting Blindness

Completed

DHA and X-Linked Retinitis Pigmentosa

Retinitis Pigmentosa | X-linked Genetic Diseases

United States
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cardiovascular Disease Risk Factors in Chinese American Immigrants (CHA-CHA)

Cardiovascular Diseases | Hypertension | Diabetes Mellitus | Metabolic Syndrome X

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts (MOHEL)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Hemophagocytic Lymphohistiocytosis (HLH) | Non Hodgkins Lymphoma | Familial Hemophagocytic Lymphohistiocytosis (FLH) | Viral-associated Hemophagocytic Syndrome (VAHS) | X-linked Lymphoproliferative...

United States
University of Aarhus
Aarhus University Hospital

Completed

Evaluation of Mobile X-ray Within the Triple Aim Method

Patient Satisfaction | X-rays; Effects | Health Impairment

Denmark
Assuta Medical Center

Completed

The Use of X-ray in Bariatric Surgeries

X-rays; Effects | Complications of Bariatric Procedures

Israel
Rare Thyroid Therapeutics International AB
Vitaccess Ltd

Completed

MCT8 Deficiency Caregiver Study

Allan-Herndon-Dudley Syndrome | Monocarboxylate Transporter 8 (MCT8) Deficiency

United Kingdom
Genethon

Active, not recruiting

Gene Therapy for X-linked Chronic Granulomatous Disease

X-Linked Chronic Granulomatous Disease

France
Veterans Medical Research Foundation
National Institute of Mental Health (NIMH); Pfizer

Completed

Ziprasidone for Improving Insulin Sensitivity in People With Schizophrenia Who Are at Risk for Diabetes

Schizophrenia | Insulin Resistance | Metabolic Syndrome X

United States
Northeastern Ohio Universities College of Medicine
Mercy Medical Center; Aultman Health Foundation; Akron General Medical Center; Forum... and other collaborators

Suspended

Efficacy of Topiramate for Weight Loss in Subjects With Metabolic Syndrome

Diabetes Mellitus, Type 2 | Metabolic Syndrome X

United States
University of Turin, Italy

Completed

Investigating My Active and Healthy Aging (my-AHA)

Cognitive Impairment | Frail Elderly Syndrome | Physical Dependence

Italy
Fundacion Miguel Servet
Hospital Universitario Getafe; Matia Foundation

Unknown

Impact of a Multicomponent Exercise Program on Functional Capacity in Frail Aged Participants With Cognitive Decline

Cognitive Impairment | Frail Elderly Syndrome

Spain
Taipei Veterans General Hospital, Taiwan

Completed

Taiwan Health Promotion Intervention Study for Elders (THISCE)

Cognitive Impairment | Frail Elderly Syndrome | Cognitive Decline
Shire

Completed

Hunter Outcome Survey (HOS) (HOS)

Hunter Syndrome

United States
Shire

Completed

Collection and Study of Cerebrospinal Fluid in Patients With Hunter Syndrome

Hunter Syndrome

United States, United Kingdom
University Hospital Southampton NHS Foundation...
NIHR Southampton Biomedical Research Centre

Withdrawn

Fortified Foods in Older Inpatients

Malnutrition | Dementia | Frail Elderly Syndrome | Aging

United Kingdom
University College Cork

Unknown

Discontinuation of Long-term Medications in Older People Entering Nursing Home Care (STOPPFrail)

Frail Elderly Syndrome | Drug-Related Side Effects and Adverse Reactions | Polypharmacy | Inappropriate Prescribing

Ireland
Genethon

Active, not recruiting

Gene Therapy for X-linked Chronic Granulomatous Disease (X-CGD) (CGD)

X-Linked Chronic Granulomatous Disease

United Kingdom
Istituto Ortopedico Galeazzi

Completed

Nutritional Status and Its Modifications After Hip Replacement (NUTRIANCA)

Frail Elderly Syndrome | Hip Arthropathy | Malnutrition; Anemia

Italy
Brigham and Women's Hospital

Completed

Preoperative Cognitive Screening in Older Spinal Surgical Patients

Cognitive Impairment | Frail Elderly Syndrome

United States
Jewish General Hospital
McGill University Health Centre/Research Institute of the McGill University...

Unknown

Frailty Heart Failure Study

Heart Failure | Frail Elderly Syndrome
Shire

Completed

A Safety and Dose Ranging Study of Idursulfase (Intrathecal) Administration Via an Intrathecal Drug Delivery Device in Pediatric Patients With Hunter Syndrome Who Have Central Nervous System Involvement and Are Receiving Treatment With Elaprase®

Hunter Syndrome

United States, United Kingdom
Shire

Completed

Observational Study to Evaluate Neurodevelopmental Status in Pediatric Patients With Hunter Syndrome (MPS II)

Hunter Syndrome | Mucopolysaccharidosis (MPS)

United States, Argentina, Mexico, Spain, United Kingdom
Astellas Gene Therapies

Completed

A Clinical Assessment Study in X-Linked Myotubular Myopathy (XLMTM) Subjects (INCEPTUS)

X-linked Myotubular Myopathy

United States, France, United Kingdom, Canada, Germany
University of Florida
Audentes Therapeutics

Completed

Respiratory Muscle Function in Untreated X-Linked Myotubular Myopathy (XLMTM)

X-linked Myotubular Myopathy

United States
Takeda
Takeda Development Center Americas, Inc.

Recruiting

A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)

Hunter Syndrome | Mucopolysaccharidosis (MPS)

United States
Shire

Completed

An Observational Study Evaluating Anti-Idursulfase Serum Antibody Response in Hunter Syndrome Patients

Hunter Syndrome

United Kingdom, United States, Brazil
Maastricht University Medical Center

Unknown

Female Subfertility: a Metabolic and Vascular Profile

Infertility | Metabolic Syndrome X

Netherlands
Rare Thyroid Therapeutics International AB
Premier Research Group plc; Egetis Therapeutics

Recruiting

Withdrawal of Tiratricol Treatment in Males With Monocarboxylate Transporter 8 Deficiency (MCT8 Deficiency) (ReTRIACt)

Monocarboxylate Transporter 8 Deficiency | Allan-Herndon-Dudley Syndrome

United States, United Kingdom, Netherlands
Boston Children's Hospital
Sandra A. Daugherty Foundation

Completed

Inflammatory Profiles of Children at High Risk for Atherosclerosis

Inflammation | Cardiovascular Disease | Hypercholesterolemia | Metabolic Syndrome X

United States
New Mexico VA Healthcare System
Bristol-Myers Squibb

Completed

The Effects of Aripiprazole on Patients With Metabolic Syndrome

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Metabolic Syndrome X

United States
SCRI Development Innovations, LLC
Novartis Pharmaceuticals

Terminated

LBH589 in Refractory Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States
PersImmune, Inc
University of California, San Diego

Unknown

Collection of Samples From Patients With MDS

Myelodysplastic Syndromes(MDS)

United States
TJ Biopharma Co., Ltd.

Recruiting

A Phase 3 Clinical Study to Evaluate Lemzoparlimab for Injection in Combination With Azacitidine (AZA) Versus AZA Monotherapy in Treatment-naïve Patients With Higher-risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes(MDS)

China
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI)

Recruiting

The National Myelodysplastic Syndromes (MDS) Study (MDS)

Myelodysplastic Syndromes (MDS)

United States, Israel
AbbVie
Celgene; Genentech, Inc.

Completed

A Study Evaluating Venetoclax Alone and in Combination With Azacitidine in Participants With Relapsed/Refractory Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States, Australia, Germany
AbbVie
Genentech, Inc.

Active, not recruiting

A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States, Australia, Canada, France, Germany, Italy, United Kingdom
The First Affiliated Hospital with Nanjing Medical...

Unknown

A Clinical Trial Evaluating the Efficacy of Ultra Low Dose of Decitabine in Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

China
James Dowling
Canadian Institutes of Health Research (CIHR); Cures Within Reach; The Joshua... and other collaborators

Recruiting

Tamoxifen Therapy for Myotubular Myopathy (TAM4MTM)

X Linked Myotubular Myopathy

United Kingdom, Canada, United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders (DANNIgene)

Hemophilia A | Hemophilia B | Cystic Fibrosis | Sickle Cell Disease | Muscular Dystrophy, Duchenne | Fragile X Syndrome | Huntington Disease | Myotonic Dystrophy | Autosomal Recessive Polycystic Kidney Disease | Neurofibromatosis-Noonan Syndrome | Muscular Dystrophy, Becker | Invasive PreNatal Diagnosis in a... and other conditions

France
National Cancer Institute (NCI)

Completed

Belinostat in Treating Patients With Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndromes | Secondary Myelodysplastic Syndromes | de Novo Myelodysplastic Syndromes

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Azacitidine and Etanercept in Treating Patients With Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndromes | Secondary Myelodysplastic Syndromes | de Novo Myelodysplastic Syndromes

United States

Clinical Trials on Fragile X Syndrome

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Azerbaijan

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Drug Interventions

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