Clinical Trials on Functional Mitral Regurgitation

Total 22655 results

Mayo Clinic

Recruiting

Watchman for Patients With Atrial Fibrillation Undergoing Transcatheter Mitral Valve Repair (WATCH-TMVR) (WATCH-TMVR)

Nonvalvular Atrial Fibrillation | Severe Degenerative Mitral Regurgitation

United States, Canada
Abbott Medical Devices

Completed

ACCESS-Europe A Two-Phase Observational Study of the MitraClip® System in Europe (ACCESS-EU)

Mitral Valve (MV) Regurgitation

Germany
University Hospital, Clermont-Ferrand

Completed

Use of Pre-operative Global Longitudinal Strain to Predict Post-operative Left Ventricular Dysfunction in Mitral Regurgitation Surgery (DysPO IM)

Severe Mitral Regurgitation | Preserved Ventricular Ejection Fraction

France
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
Fundación para la Investigación Biosanitaria del...
Meditrial Europe Ltd.

Not yet recruiting

Early Transcatheter Mitral Valve Repair After Myocardial Infarction (EMCAMI)

Acute Mitral Regurgitation

Spain, Italy, Netherlands, Israel
Edwards Lifesciences

Recruiting

MiCLASP Post Market Clinical Follow-Up (PMCF) Study (MiCLASP)

Mitral Regurgitation | Mitral Insufficiency

Switzerland, Germany, Austria, Greece, Italy, Netherlands, Poland, Spain, United Kingdom
Medtentia International Ltd Oy

Terminated

Study on Safety and Performance of Medtentia Mitral Valve Repair System in Surgical Repair of Mitral Regurgitation

Mitral Regurgitation | Mitral Insufficiency

Finland
Universitätsklinikum Hamburg-Eppendorf
University Hospital, Bordeaux; Montreal Heart Institute

Recruiting

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry (CHOICE-MI)

Mitral Regurgitation

Switzerland, United States, Denmark, United Kingdom, France, Canada, Germany, Australia, Italy, Norway
Edwards Lifesciences

Active, not recruiting

SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation (SAPIEN M3 EFS)

Mitral Regurgitation | Mitral Disease

United States, Canada
Medtentia International Ltd Oy

Completed

5-Year Follow-Up Safety and Performance Evaluation of the Medtentia Annuloplasty Ring in Adults

Mitral Regurgitation | Mitral Insufficiency

Finland
Instituto Dante Pazzanese de Cardiologia
Edwards Lifesciences

Recruiting

Randomized Trial of Transcatheter Valve-in-Valve vs Redo Surgery for Bioprosthetic Mitral Dysfunction

Mitral Prosthetic Valve Stenosis and Regurgitation

Brazil
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Evaluation of Mitral Valve Insufficiency Under General Anesthesia (MITIGATE)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Netherlands
Michele De Bonis

Completed

Durability at 20 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation

Mitral Valve Disease

Italy
Cardiovalve Ltd.
Meditrial Europe Ltd.; Meditrial SrL

Recruiting

AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System (AHEAD)

Mitral Regurgitation | Mitral Valve Disease

Germany, Italy, Greece
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE MRace: Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant (EXPLORE MRace)

Mitral Valve Disease

Brazil
P+F Products + Features GmbH
Meditrial USA Inc.

Not yet recruiting

Munich Transcatheter Mitral Valve Safety and Effectiveness (MUSE)

Mitral Regurgitation | Mitral Valve Disease

Brazil, Argentina, Chile
Polares Medical SA

Terminated

Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation (EXPLORE MR)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Switzerland, Germany
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Multimodality Imaging Assessment of the Severity of Mitral Regurgitation

Mitral Regurgitation

China
Tioga Cardiovascular, Inc.

Not yet recruiting

Feasibility Study of the Tioga TMVR System

Mitral Regurgitation
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Not yet recruiting

Haemodynamics of Mitral Regurgitation Reduction (STRESS-MR)

Mitral Regurgitation
Shanghai Zhongshan Hospital

Not yet recruiting

The Multicenter Clinical Trial of a Novel TEER Decive (V-CLASP Trial)

Mitral Regurgitation
Abbott Medical Devices

Recruiting

Cephea Early Feasibility Study

Mitral Regurgitation

United States, Canada
Shanghai Shenqi Medical Technology Co., Ltd

Recruiting

SQ-Kyrin TMVr FIM Study

Mitral Regurgitation

China
Shanghai NewMed Medical Co., Ltd.

Recruiting

Valveclip® Transcatheter Mitral Valve Repair Study

Mitral Regurgitation

China
CardioMech AS

Recruiting

EFS of the CardioMech MVRS

Mitral Regurgitation

United States
Haukeland University Hospital

Recruiting

3D Echocardiography and Cardiovascular Prognosis in Mitral Regurgitation (3D-PRIME)

Mitral Regurgitation

Norway
Edwards Lifesciences

Recruiting

The ENCIRCLE Trial (ENCIRCLE)

Mitral Regurgitation | Mitral Valve Insufficiency

United States, Netherlands, Israel, Australia, Canada, United Kingdom
Atlantic Health System

Recruiting

The Effects of Degenerative Mitral Regurgitation on Cardiac Structure and Function, Symptoms, and Exercise Capacity

Mitral Regurgitation

United States
HighLife SAS
ICON plc

Recruiting

Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk

Mitral Regurgitation

Belgium, France, Germany, Australia, United Kingdom, Poland
Cardiovalve Ltd.
Meditrial Europe Ltd.

Recruiting

Cardiovalve Transfemoral System - FIM Study

Mitral Regurgitation

Lithuania
Mayo Clinic

Completed

Invasive Hemodynamic Response to Transcatheter Edge-to-Edge Mitral Valve Repair

Mitral Regurgitation

United States
Abbott Medical Devices

Active, not recruiting

MitraClip China PMS

Mitral Regurgitation

China
Michele De Bonis

Completed

Is Mitral Annuloplasty an Effective Treatment for Severe Atrial Functional MR?

Mitral Regurgitation

Italy
Henry Ford Health System

Completed

Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair

Mitral Regurgitation

United States
Edwards Lifesciences

Completed

MITRAFIT- Cardinal Adjustable Mitral Repair Follow-up International Postmarketing Surveillance (PMS) (MITRAFIT)

Mitral Regurgitation

Germany, Italy
Population Health Research Institute

Completed

A Pan-Canadian, Retrospective Evaluation of MitraClip Safety and Efficacy (PREMISE)

Mitral Regurgitation

Canada
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Manchester Metropolitan University

Completed

Percutaneous Mitral Valve Intervention: Predicting Improvements in Left Ventricular Performance (PMVI-PiP)

Mitral Regurgitation | Mitral Valve Insufficiency

United Kingdom
University Hospital, Basel, Switzerland
Schweizerische Herzstiftung

Active, not recruiting

Prognosis in Asymptomatic Mitral Regurgitation (PAMIR) Study

Mitral Regurgitation

Germany, Switzerland
Cardiovalve Ltd.

Withdrawn

Feasibility Study of Patients With Severe MR Treated With the Cardiovalve TMVR System

Mitral Regurgitation

Greece, Poland
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Third Affiliated Hospital... and other collaborators

Not yet recruiting

Enhanced External Counter Pulsation on Afterload Mismatch Rate in Post-TEER (PAMPER)

Mitral Regurgitation

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
First Affiliated Hospital, Sun Yat-Sen University; First Affiliated Hospital... and other collaborators

Recruiting

TEER for Severe DMR of Low to Intermediate Surgery Risk

Mitral Regurgitation

China
ITMO University

Recruiting

Mitral Splay Sign, Its Mechanism and Association With Severity of Regurgitation

Mitral Regurgitation

Russian Federation
Peijia Medical Technology (Suzhou) Co., Ltd.
West China Hospital; Second Affiliated Hospital, School of Medicine, Zhejiang... and other collaborators

Recruiting

Safety and Efficacy of the HighLife Transcatherter Mitral Valve Replacement System in Patients With Moderate-severe or Severe Mitral Regurgitation in China

Mitral Regurgitation

China
Medtronic Cardiovascular

Recruiting

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial (APOLLO-EU)

Mitral Regurgitation

Spain, Denmark, France, United Kingdom, Germany, Netherlands, Switzerland
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry (PRIME-MR)

Mitral Regurgitation

United States, France, Germany
Rabin Medical Center

Recruiting

Change in LVEF Following Transcatheter Mitral Edge-To-Edge Repair (MITRA-EF)

Mitral Regurgitation

Israel
Medical University of Vienna
LSI SOLUTIONS, Inc.

Recruiting

Mi-STITCH™ and Mi-KNOT™ Device Technologies - Improvement of Mitral Valve Repair

Mitral Regurgitation | Mitral Valve Insufficiency

Austria
HighLife SAS

Recruiting

HighFLO Study - HighLife Trans-septal Mitral Valve Replacement (TSMVR) Feasibility Study of the Open Cell CLARITY Valve (HighFLO)

Mitral Regurgitation

Belgium, France, Poland, Germany, Australia, United Kingdom
Montefiore Medical Center

Recruiting

Use of Phenylephrine for Assessment of Mitral Regurgitation Severity

Mitral Regurgitation

United States
Nantes University Hospital
Abbott; Ministère de la Santé

Recruiting

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery (MITRA-HR)

Mitral Regurgitation

France, Monaco

Clinical Trials on Functional Mitral Regurgitation

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