Clinical Trials on GVHD (Acute or Chronic)

Total 4691 results

Xuzhou Medical University

Recruiting

Safety and Efficacy of Iguratimod in the Treatment of Chronic GVHD

cGVHD

China
Shanghai Jiao Tong University School of Medicine
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Unknown

Valproic Acid With Methylprenisonlone for the Treatment of Acute GVHD

Peripheral Blood Stem Cell Transplantation | aGVHD

China
Equillium
Biocon Limited

Recruiting

A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR)

Graft Versus Host Disease | GVHD | aGVHD | Acute-graft-versus-host Disease | Acute GVHD

United States, Korea, Republic of, Israel, Spain, Germany, Belgium, Italy, Australia, France, Canada, Portugal
Equillium
Biocon Limited

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD (EQUATE)

GVHD | GVHD, Acute | aGVHD | Acute-graft-versus-host Disease

United States
Shanghai Jiao Tong University School of Medicine

Completed

PT-CY With or Without Low-dose ATG for Lymphoid Malignancies Undergoing Allo-HSCT

GVHD, Acute

China
daphne brockington

Unknown

Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD (CARE)

Chronic GVHD After HCT for Cancer or Immune Disease

Canada
University of Salamanca

Recruiting

Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD)

GVHD, Chronic | GVHD,Acute

Spain
Mats Remberger
The Swedish Research Council

Recruiting

Decidua Stroma Cells for Steroid Resistent Acute Graft-versus-host Disease After Allo-HSCT (2017-00355)

GVHD, Acute

Sweden, Norway, Denmark
CSL Behring

Terminated

Exploratory Safety Study of ALD518 in Subjects With Steroid-refractory Acute Graft Versus Host Disease (GVHD) (ALD518-010)

Acute GvHD

United States
Nationwide Children's Hospital

Terminated

Infliximab and Basiliximab for Treatment of Steroid Refractory Acute Graft Versus Host Disease

Graft Versus Host Disease | Acute GVH Disease | Steroid Refractory GVHD

United States
Weill Medical College of Cornell University

Terminated

Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT)

Glucocorticosteroid Refractory Acute GVHD

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Universitätsklinikum Hamburg-Eppendorf; The Chaim Sheba Medical Center; Hospital...

Completed

Electronic Database for the Follow up of the ATG_FamilyStudy (AFF)

Acute Leukemia | Stem Cell Transplant Complications | GVHD, Chronic

Italy
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids (MTX-aGVHD)

Stem Cell Transplant Complications | GVHD, Acute | GVH - Graft Versus Host Reaction | Allogeneic Disease

France
Duke University

Recruiting

Prebiotic Galacto-oligosaccharide and Acute GVHD

Acute GVHD

United States
Shanghai iCELL Biotechnology Co., Ltd, Shanghai...

Not yet recruiting

Safety and Efficacy Study of hAESCs Therapy for aGVHD (aGVHD，hAESCs)

GVHD,Acute
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill

Completed

Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT)

Acute GVHD

United States
Chinese PLA General Hospital

Recruiting

Role of aGVHD Biomarkers on aGVHD Risks (GVHD)

Biomarker | GVHD,Acute

China
Ciusss de L'Est de l'Île de Montréal
Centre hospitalier de l'Université de Montréal (CHUM)

Not yet recruiting

Improvement of Women's Health After Allogeneic Stem Cell Transplantation (SaFeGreff)

GVHD, Chronic
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Completed

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

GVHD | Graft-versus-host-disease | GVHD, Acute

United States
Ossium Health, Inc.

Withdrawn

Mesenchymal Stem Cells (MSCs) for Steroid Refractory Acute GVHD (SR-aGVHD)

GVHD,Acute
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Study to Evaluate Steroid-free Treatment for Standard-Risk aGVHD (BMT CTN 1501)

Acute GVHD

United States
Shanghai General Hospital, Shanghai Jiao Tong University...

Unknown

Ruxolitinib and Steroid as First Line Therapy for Acute GVHD

Acute GVHD

China
Washington University School of Medicine

Recruiting

Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease

Chronic GVHD | Acute Graft-versus-host Disease | Chronic Graft-versus-host Disease | Acute GVHD

United States
Rigshospitalet, Denmark
Novo Nordisk A/S

Completed

Systematic Symptom Identification With Disease Specific PROM to Assess Symptoms of Chronic GVHD in Outpatient Care in Patients Post HSCT (SIMPly-CARE)

Hematological Malignancy | GVHD, Chronic

Denmark
Central Hospital, Nancy, France
Saint-Louis Hospital, Paris, France

Not yet recruiting

Wharton Jelly Mesenchymal Stromal Cells as GVHD Prophylaxis (HAPLO-GEL)

Graft Failure | GVHD,Acute | Allogeneic Disease
Shanghai General Hospital, Shanghai Jiao Tong University...

Recruiting

SHR0302 and Steroid as First Line Therapy for Chronic GVHD

Chronic GVHD

China
Tata Memorial Centre

Recruiting

Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant

Musculoskeletal Disease Other | GVHD, Chronic

India
Sichuan University

Not yet recruiting

MAP-guided Preemptive Therapy of aGvHD by Ruxolitinib

GVHD | Acute Stem Cell Transplant Complications

China
Sichuan University

Recruiting

MAP-guided Preemptive Therapy of aGvHD

Stem Cell Transplant Complications | GVHD,Acute

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alpha 1 Anti-Trypsin (AAT) in Treating Patients With Acute Graft-Versus-Host Disease GVHD)

Graft-Versus-Host Disease (GVHD) Acute on Chronic

United States
Fred Hutchinson Cancer Center

Active, not recruiting

Chronic GVHD Response Measures Validation

Graft vs Host Disease

United States
Henry Ford Health System

Recruiting

CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease

GVHD,Acute

United States
Innovent Biologics (Suzhou) Co. Ltd.

Terminated

A Study of IBI377 in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

GVHD,Acute

China
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801)

Chronic GVHD

United States
Massachusetts General Hospital
Novartis

Terminated

Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT

Graft Versus Host Disease

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor (OPTISAGE)

GVHD
Karolinska University Hospital

Completed

Photochemotherapy and Graft-versus-leukemia in Acute-leukemia

AML | ALL | Acute GVHD | Tumor Immunity

Sweden
The Korean Society of Hematopoietic Stem Cell Transplantation
Hoffmann-La Roche

Unknown

Study of Rituximab in Patients With Steroid-Refractory Chronic Graft-Versus-Host Disease

Steroid-Refractory Chronic GVHD

Korea, Republic of
Hadassah Medical Organization

Completed

Alefacept for Chronic Graft Versus Host Disease

Resistant Chronic GVHD

Israel
Centre Hospitalier Universitaire de Nice

Completed

Use of RespinPAD in Elderly Patients (RESPINPAD)

Acute or Chronic Respiratory Pathologies

France
MaaT Pharma

Recruiting

MaaT013 as Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients (ARES)

Acute Graft Versus Host Disease in Intestine | Steroid Refractory GVHD

Spain, France, Germany, Austria, Belgium, Italy
Gilead Sciences
Ohio State University

Terminated

Phase I Study of Milatuzumab for Graft Versus Host Disease

Myelodysplastic Syndrome | Chronic Myelogenous Leukemia (CML) | Multiple Myeloma (MM) | GVHD (Acute or Chronic) | Acute Myeloid or Lymphoblastic Leukemia (AML or ALL) | Non-Hodgekin Lymphoma (NHL-both Follicular & Diffuse Large Cell) | Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia...

United States
MaaT Pharma

Available

Early Access Program With MaaT013 in Steroid-refractory Acute Gastrointestinal Graft Versus Host Disease (ATLAS)

Acute Graft Versus Host Disease in Intestine | Steroid Refractory GVHD

France
M.D. Anderson Cancer Center

Completed

Feasibility Study of Collecting Multicenter Chronic GVHD Data

Graft-Versus-Host Disease

United States
University of Freiburg

Active, not recruiting

Analysis of Intestinal Defensin Expression in Acute GVHD

Ulcerative Colitis | GVHD,Acute | Morbus Crohn

Germany
University of Alabama at Birmingham

Not yet recruiting

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

Myelodysplastic Syndromes | Myeloproliferative Disorders | Acute Leukemia | GVHD,Acute

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

PROACTIVE: Preventing Acute/Chronic GVHD With TocIlizumab Combined With GVHD Prophylaxis Post allogEneic Transplant

Hematologic Malignancy

United States
John Levine

Completed

Itacitinib for Low Risk GVHD

GVHD | Low Risk Acute Graft-versus-host Disease | Graft-versus-host-disease

United States
Peking University People's Hospital

Recruiting

MTX and Steroid for aGVHD Treatment

Acute GVH Disease

China
Peking University People's Hospital

Active, not recruiting

MTX and Steroid as First-line Therapy for aGVHD

Acute GVH Disease

China

Clinical Trials on GVHD (Acute or Chronic)

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