Clinical Trials on Gastroesophageal-junction Cancer in Belgium

Total 1802 results

Astellas Pharma Global Development, Inc.

Active, not recruiting

A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer (Spotlight)

Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer | Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer | Metastatic Gastric Adenocarcinoma or Cancer | Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma

United States, Australia, Belgium, Brazil, Canada, Chile, China, Colombia, France, Germany, Israel, Italy, Japan, Korea, Republic of, Mexico, Peru, Poland, Spain, Taiwan, United Kingdom
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Recruiting

A Study of Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)

HER2-positive Advanced Gastric Cancer | HER2-positive Gastroesophageal Junction Adenocarcinoma

Austria, Belgium, Germany, Italy
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)

Gastric Cancer | Gastroesophageal Junction Cancer

United States, Belgium, Brazil, Canada, Chile, China, Estonia, France, Germany, Guatemala, Israel, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Malaysia, Philippines, Poland, Russian Federation, Singapore, Taiwan, Ukraine, United...
European Organisation for Research and Treatment...

Terminated

Epirubicin Hydrochloride, Cisplatin, and Fluorouracil or Capecitabine With or Without Lapatinib Ditosylate as First-Line Therapy in Treating Patients With Stomach Cancer or Gastroesophageal Junction Cancer

Gastric Cancer | Adenocarcinoma of the Gastroesophageal Junction

Belgium, Portugal, Germany
Sumitomo Pharma America, Inc.

Completed

A Study of BBI608 Plus Weekly Paclitaxel to Treat Gastric and Gastro-Esophageal Junction Cancer (BRIGHTER)

Gastric Cancer | Gastroesophageal Junction Cancer

United States, Hungary, Spain, China, Brazil, France, Australia, Czechia, Germany, Israel, Canada, United Kingdom, Japan, Belgium, Romania, Italy, Poland, Lithuania, Korea, Republic of, Bulgaria, Estonia, Russian Federation
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300)

Unresectable, Recurrent, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma | Gastric Cancer Third Line

Spain, Italy, Australia, Korea, Republic of, Belgium, France, Poland, United States, Czechia, Germany
Erasme University Hospital
Fonds National de la Recherche Scientifique; Fonds Erasme

Completed

Uric Acid Effects on Endothelium and Oxydative Stress

Hypertension | Oxidative Stress | Cardiovascular System | Endothelial Function

Belgium
Centre Hospitalier Universitaire Saint Pierre

Unknown

Lymphatic Occlusion Pressure in Lower Limb

Lymphatic Function

Belgium
Cliniques universitaires Saint-Luc- Université...

Unknown

Determinants of Efficacy of EsophyX Treatment in Gastro-Esophageal Reflux Disease

Gastroesophageal Reflux Disease

Belgium
Merus N.V.
Chiltern International Inc.; Q2 Solutions; Oncology Therapeutic Development (OTD) and other collaborators

Recruiting

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Gastric Cancer | Colorectal Cancer | NSCLC | Head and Neck Squamous Cell Carcinoma | HNSCC | Advanced/Metastatic Solid Tumors | Gastroesophageal-junction Cancer

United States, Spain, Belgium, France, Netherlands, United Kingdom
Millennium Pharmaceuticals, Inc.

Terminated

A Study of MLN0264 in Participants With Cancer of the Stomach or Gastroesophageal Junction

Adenocarcinoma of the Stomach | Gastroesophageal Junction Expressing Guanylyl Cyclase C

United States, Belgium, Spain, United Kingdom
Universitaire Ziekenhuizen KU Leuven

Unknown

Study of Polymorphisms in pear1 Gene Link to Platelet Activation and Signaling Pathway Variations

Platelet Function

Belgium
VIPUN Medical

Completed

Clinical Validation of the VIPUN GMS as a Gastric Motility Monitoring System

Gastric Motor Function

Belgium
Jules Bordet Institute
Innate Pharma

Withdrawn

Assessment of Metabolic & Path Response w/ RCT & ImT Before Surgery in Locally Advanced Esoph and Gastro-esoph Jction CA (ARTEMIS-Eso)

Adenocarcinoma of the Gastroesophageal Junction | Squamous Cell Carcinoma of the Esophagus | Adenocarcinoma of the Esophagus

Belgium
University Hospital, Antwerp

Terminated

Car Safety Seat and Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease and Position

Belgium
ALX Oncology Inc.
Eli Lilly and Company

Recruiting

A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)

Gastric Cancer | Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

United States, Spain, France, Korea, Republic of, Taiwan, United Kingdom, Japan, Singapore, Belgium, Czechia, Italy
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Brugmann University Hospital

Completed

Influence of Sevoflurane and Propofol on Maximum Muscular Strength, Speed of Contraction and Relaxation

Anesthesia, General | Neuromuscular Transmission Disorders

Belgium
Pierre Wauthy

Completed

Study of Gastro-oesophageal Reflux in Patients Having Had Bariatric Surgery

Gastroesophageal Reflux

Belgium
Universitair Ziekenhuis Brussel

Completed

48 Hours Esophagal pH-monitoring With and Without Gaviscon

Gastroesophageal Reflux

Belgium
United Pharmaceuticals

Completed

SWAN: Study on the Tolerance and Efficacy of a New Anti-regurgitation Formula (PC-2016-01) (SWAN)

Gastroesophageal Reflux

Belgium
University of Liege

Unknown

Effects of Preconditioning With Sevoflurane During Organ Procurement From Brain Dead Donors: Impact on Early Function of Liver Allografts

Post-transplantation Liver Allograft Function

Belgium
Sanofi

Completed

Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Belgium
Erasme University Hospital

Recruiting

Endomina Suturing Device as a Treatment of GERD.

GERD

Belgium
Daiichi Sankyo
AstraZeneca

Recruiting

Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)

Gastroesophageal Junction Adenocarcinoma | Gastric Cancer, Adenocarcinoma

Hong Kong, Korea, Republic of, France, United Kingdom, Spain, China, Ireland, Brazil, Japan, Singapore, Belgium, Israel, Russian Federation, Argentina, Chile, Hungary, Poland, Portugal, Taiwan, Turkey, Ukraine, Germany, Romania, Italy
United Pharmaceuticals

Completed

Study on the Tolerance and Efficacy of a New Anti Regurgitation Formula (SONAR)

Gastroesophageal Reflux

Belgium, France
Universitair Ziekenhuis Brussel

Unknown

Maximal Effort-dependent Respiratory Flow Rates

Lung Function

Belgium
University Hospital, Ghent

Completed

Evaluation of the Optimal Technique for Determination of Renal Function of Critically Ill Patients

Critical Illness | Renal Function

Belgium
Amgen

Recruiting

Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer (FORTITUDE-102)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Korea, Republic of, United States, Israel, Italy, Spain, Switzerland, Canada, Australia, Germany, United Kingdom, Austria, France, Japan, Taiwan, China, Belgium, Poland, Thailand, Czechia, Singapore, Hungary, Argentina, Brazil, Romania, Portuga... and more
Amgen
Zai Lab (China only)

Recruiting

Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (FORTITUDE-101)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Canada, Japan, United States, Korea, Republic of, China, Italy, Australia, Sweden, Spain, Taiwan, France, Belgium, Denmark, Thailand, Turkey, Czechia, Bulgaria, Brazil, Norway, Mexico, Poland, Estonia, Israel, Greece, Romania, Chile, Peru, Po... and more
KU Leuven
Belgian Cancer Registry

Completed

Functional Outcomes and QoL in Patients With High Versus Low and Intermediate Risk Prostate Cancer Treated by RARP

Quality of Life | Prostate Cancer | Erectile Function | Urinary Function

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Prucalopride Treatment for Refractory Gastro-esophageal Reflux Disease

GERD

Belgium
Jules Bordet Institute

Completed

Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers (MOMENTUM1)

Metastatic Colorectal Cancers | Metastatic Gastric Cancers | Metastatic Oesophageal Cancers | Metastatic Pancreatic Cancers | Metastatic Biliary Cancers | Metastatic Breast Cancers

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Bitter Tastants and Reflux

Gastro Esophageal Reflux

Belgium
Eli Lilly and Company

Completed

A Study of Ramucirumab (LY3009806) in Combination With Paclitaxel in Participants With Gastric Cancer

Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

Italy, United States, Spain, Ukraine, Germany, Greece, Czechia, Turkey, Belgium, Sweden, Canada
Universitair Ziekenhuis Brussel

Recruiting

Prospective Evaluation of pH-impedance Tracings According to the Wingate Consensus, and Influence on GERD Classification According to the Lyon Consensus (WinPro)

GERD

Belgium
Novartis

Completed

Effects of AFQ056 and Baclofen on Meal-Induced Gastroesophageal Reflux

Gastroesophageal Reflux Disease

France, Germany, Belgium, Switzerland
Erasme University Hospital

Unknown

Study of Catheter Based Renal Denervation Therapy in Hypertension (DEPART)

Renal Function | Resistant Hypertension | Ambulatory Blood Pressure | Renal Denervation

Belgium
AstraZeneca

Completed

Study to Investigate the Pharmacodynamic Effect of a Single Dose of AZD2516 in Healthy Male Subjects

Reflux

Netherlands, Belgium
Vrije Universiteit Brussel

Completed

Influence of Expiration Lente Prolongée on Gastro-oesophageal Reflux

Gastro-esophageal Reflux

Belgium
Hasselt University

Not yet recruiting

GReen And Healthy Schools (GRAS)

Cognitive Change | Emotions | Cognitive Function 1, Social | Weight, Body | Pollution; Exposure

Belgium
EndoGastric Solutions

Completed

Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD)

Hiatal Hernia | Gastroesophageal Reflux Disease

Belgium, France, Sweden
Vrije Universiteit Brussel

Completed

Safety Study of Airway Clearance Techniques in Infants.

Gastro-esophageal Reflux

Belgium
Shire

Terminated

An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients

Gastroesophageal Reflux Disease

United Kingdom, Switzerland, Netherlands, Belgium, France, Germany
Universitaire Ziekenhuizen KU Leuven

Unknown

The Effect of Chlorpromazine on Esophageal Sensitivity in Healthy Volunteers.

Esophageal Reflux

Belgium
NDO Surgical, Inc.

Terminated

A Study to Determine the Effectiveness of Endoscopic Full-Thickness Plication for the Treatment of GERD

Gastroesophageal Reflux Disease (GERD)

United States, Belgium, Germany
Universitaire Ziekenhuizen KU Leuven

Completed

Effect of Citalopram on Reflux Episodes in Healthy Volunteers

Gastro Esophageal Reflux

Belgium
Gilead Sciences

Completed

Study to Evaluate the Efficacy and Safety of Andecaliximab Combined With Nivolumab Versus Nivolumab Alone in Adults With Unresectable or Recurrent Gastric or Gastroesophageal Junction Adenocarcinoma

Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

Spain, United States, Hungary, United Kingdom, Italy, France, Poland, Australia, Belgium
Incyte Corporation

Completed

INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors

Hepatocellular Carcinoma | Colorectal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma | Castration Resistant Prostate Cancer | Gastric/ Gastroesophageal Junction | Squamous Carcinoma...

United States, Spain, France, United Kingdom, Italy, Belgium

Clinical Trials on Gastroesophageal-junction Cancer in Belgium

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