Clinical Trials on Gastrointestinal Adenocarcinomas

Total 31208 results

Adela, Inc

Recruiting

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease (CAMPERR)

Sarcoma | Lymphoma | Cervical Cancer | Leukemia | Stomach Cancer | Breast Cancer | Head and Neck Cancer | Multiple Myeloma | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Brain Cancer | Bladder Cancer | Endometrial Cancer | Thyroid Cancer | Renal Cancer | Hepatobiliary...

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Colorectal Carcinoma | Stage III Colon Cancer AJCC v7 | Stage III Rectal Cancer AJCC v7 | Stage IIIA Colon Cancer AJCC v7 | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Colon... and other conditions

United States
National Cancer Institute (NCI)

Withdrawn

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Hematopoietic and Lymphoid Cell Neoplasm | Lynch Syndrome | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central... and other conditions

United States, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

Stage IV Anal Cancer AJCC v8 | Recurrent Cervical Carcinoma | Metastatic Malignant Neoplasm | Stage IV Penile Cancer AJCC v8 | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | Stage IV Cervical Cancer AJCC v8 | Stage IVA Cervical Cancer AJCC v8 | Stage IVB Cervical Cancer AJCC v8 | Stage... and other conditions

United States
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations (DETERMINE)

Colorectal Neoplasms | Ovarian Neoplasms | Solid Tumor | Gallbladder Neoplasms | Prostatic Neoplasm | Pancreatic Neoplasm | Lung Neoplasm | Haematological Malignancy | Urinary Bladder Neoplasm | Skin Neoplasm | Salivary Gland Neoplasm

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

Malignant Solid Neoplasm | Recurrent Prostate Carcinoma | Localized Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage IIA Cervical Cancer FIGO 2018 | Stage IIB Cervical Cancer FIGO 2018 | Stage IIIA Cervical Cancer FIGO 2018 | Stage IIIB Cervical Cancer... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung... and other conditions

United States
National Cancer Institute (NCI)

Withdrawn

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Cervical Carcinoma | Recurrent Melanoma | Vaginal Carcinoma | Esophageal Carcinoma | Mucosal Melanoma | Mucosal Melanoma of the Head and Neck | Oral Cavity Mucosal Melanoma | Stage II Vulvar Cancer AJCC v7 | Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 and other conditions

United States
Thompson Cancer Survival Center

Recruiting

Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis

Laryngeal Cancer | Esophageal Cancer | Oropharynx Cancer | Oral Cavity Cancer | Mediastinal Cancer | Head and Neck Cancers - Tonsils | Chest Wall Tumor | Radiation Mucositis

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Natural History and Genetics of Food Allergy and Related Conditions

Eosinophilic Esophagitis | Atopic Dermatitis | Food Allergy | Loeys-Dietz Syndrome

United States
dr. Muhammad Abdelhafez Mahmoud, MD

Completed

Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair (EArAzygousvp)

Leak, Anastomotic | Tracheo-Esophageal Fistula With Atresia of Esophagus | Azygos Vein Preservation Versus Disconnection | Stricture Esophagus | Pneumonitis; Postoperative

Egypt
University of Helsinki
Royal Children's Hospital; Murdoch Childrens Research Institute; University of... and other collaborators

Active, not recruiting

Healthcare Transition of Adolescents With Chronic Health Conditions

Liver Diseases | Kidney Diseases | Diabetes | Rheumatic Diseases | Inflammatory Bowel Diseases | Neurologic Disorder | Congenital Heart Disease | Transition

Australia, Finland
Hospital de Clinicas de Porto Alegre

Completed

Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study (CASA)

Muscle Weakness | Obstructive Sleep Apnea | Swallowing Disorder | Muscle Disorder | Face | Breathing, Sleep-Disordered

Brazil
Central Hospital, Nancy, France

Enrolling by invitation

Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up (AADT1D)

Autoimmune Diseases | Type 1 Diabetes | Graves Disease | Celiac Disease | Vitiligo | Hashimoto Disease | Addison Disease

France
Brigham and Women's Hospital

Withdrawn

Hyaluronidase in Treating Oral Microstomia in Patients With Sclerosing Skin Disease

Morphea | Scleroderma | CREST Syndrome | Microstomia | Scleromyxedema
National Institute of Allergy and Infectious Diseases...
Autoimmunity Centers of Excellence

Terminated

T and B Cell Responses in Autoimmune Diseases (SRA01)

Multiple Sclerosis | Arthritis, Rheumatoid | Psoriasis | Crohn's Disease | Type 1 Diabetes Mellitus

United States
Georgetown University
National Institute of Environmental Health Sciences (NIEHS); University of...

Completed

Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome

Irritable Bowel Syndrome | Fibromyalgia | Interstitial Cystitis | Chronic Fatigue Syndrome | Gulf War Illness | Multiple Chemical Sensitivity

United States
National Institute of Neurological Disorders and...

Completed

A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia

Multiple Sclerosis | Parkinson Disease | Chronic Dysphagia

United States
InnoCon Medical
Odense University Hospital; Aarhus University Hospital; Herlev Hospital

Recruiting

Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)

Urinary Incontinence | Fecal Incontinence | Urinary Incontinence, Urge | Nocturia | Fecal Incontinence With Fecal Urgency | Urinary Frequency More Than Once at Night | Incontinence, Nighttime Urinary | Bowel Disorders Functional

Denmark
Jamp Pharma Corporation

Recruiting

The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications. (EASE PAIN)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Ankylosing Spondylitis

Canada
Martin-Luther-Universität Halle-Wittenberg

Not yet recruiting

Treatment of Classic Mid-trimester PPROM by Means of Continuous Amnioinfusion (AmnionFlush)

Necrotizing Enterocolitis | Intracranial Hemorrhages | Bronchopulmonary Dysplasia

Germany
University of California, San Diego

Completed

No Post Intubation Laryngeal Symptoms (No-PILS)

Dysphagia | Anesthesia Morbidity | Intubation Complication | Anesthesia Intubation Complication | Dysphonia | Anesthesia; Reaction | Anesthesia Complication | Anesthesia; Adverse Effect | Sore-throat | Throat Disorder | Throat; Wound | Throat Injury

United States
Beijing Anzhen Hospital

Completed

Tissue Oxygenation During Treatment of Infant Congenital Heart Defects

Acute Kidney Injury | Hypoxia-Ischemia, Brain | Mesenteric Ischemia

China
Queen Mary University of London

Unknown

Identification of Autoantigens in EGPA and Severe Eosinophilic Asthma (IDEA)

Eosinophilic Esophagitis | Churg-Strauss Syndrome | Eosinophilic Asthma | Eosinophilic Pneumonia

United Kingdom
AbbVie
Raffeiner GmbH

Completed

Assessment of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Crohn's Disease and Ulcerative Colitis Patients´ Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice (Adherence)

Rheumatoid Arthritis | Plaque Psoriasis | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis | Crohn´s Disease
Arkansas Children's Hospital Research Institute

Completed

Assessing Risk of Food Insecurity Within Households of Children With Food Allergy

Asthma | Allergic Rhinitis | Eosinophilic Esophagitis | Atopic Dermatitis | Food Allergy

United States
Huang, Jeannie, M.D.
University of California, San Diego

Completed

MD2Me - Texting to Promote Chronic Disease Management

Type 1 Diabetes | Cystic Fibrosis | Inflammatory Bowel Disease | Chronic Disease Management

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage... and other conditions

United States
University of California, San Francisco
Bristol-Myers Squibb Foundation

Completed

Patient Portal and Navigation Program in Providing Information for Asian American Cancer Patients

Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Malignant Neoplasm | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal... and other conditions

United States
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer

Lymphoma | Leukemia | Breast Cancer | Head and Neck Cancer | Chronic Myeloproliferative Disorders | Colorectal Cancer | Small Intestine Cancer | Lung Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
University of Arkansas

Withdrawn

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Pancreatic Neoplasms | Colorectal Neoplasms, Hereditary Nonpolyposis | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Hereditary Pancreatitis | Ataxia Telangiectasia | Peutz-Jegher's Syndrome | Familial Atypical Mole-Malignant Melanoma Syndrome

United States
Celldex Therapeutics
Merck Sharp & Dohme LLC

Completed

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Melanoma | Follicular Lymphoma | Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Fallopian Tube Cancer | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | ... and other conditions

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Terminated

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Primary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditions

United States
Celldex Therapeutics

Recruiting

A Study of CDX-585 in Patients With Advanced Malignancies

Renal Cell Carcinoma | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Hepatic Cancer | Bladder Urothelial Carcinoma | Other Solid Tumors

United States
Phanes Therapeutics

Recruiting

A Study of PT217 in Patients With Advanced Refractory Cancers Expressing DLL3 (the SKYBRIDGE Study)

Small Cell Lung Cancer (SCLC) | Large Cell Neuroendocrine Cancer (LCNEC) | Neuroendocrine Prostate Cancer (NEPC) | Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)

United States
Monte Rosa Therapeutics, Inc

Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NSCLC | Prostate Cancer | SCLC | DLBCL | High Grade Neuroendocrine Cancer | L-MYC and N-MYC Amplified Solid Tumors | NSCLC With High or Low L-MYC or N-MYC Expression | HR-positive, HER2-negative Breast Cancer

United States, Canada
VastBiome

Recruiting

The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors (PARADIGM)

Renal Cell Carcinoma | Non-Small-Cell Lung Carcinoma | Malignant Melanoma | Triple-Negative Breast Cancer

United States
Simcha IL-18, Inc.
Merck Sharp & Dohme LLC

Recruiting

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

Melanoma | Carcinoma | Renal Cell Carcinoma | Cancer | Solid Tumor | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Triple-negative Breast Cancer | MSI-High

United States
Western Sydney Local Health District
Bristol-Myers Squibb; University of Western Sydney

Recruiting

Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin Toxicity (ICEMELT)

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Gastric Cancer | Mesothelioma | Endometrial Cancer | Lung Cancer, Nonsmall Cell

Australia
National Cancer Institute (NCI)

Recruiting

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Metastatic Malignant Neoplasm in the Soft Tissues | Metastatic Malignant Neoplasm in the Viscera and other conditions

United States, Puerto Rico
Biomica Ltd.

Active, not recruiting

A First-in-human (FIH) Combination Treatment Study With a Single Dose Level of BMC128

Melanoma | Renal Cell Carcinoma | Non-small Cell Lung Cancer

Israel
HiberCell, Inc.
Covance

Terminated

A Study of HC-7366 to Establish the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D)

Clear Cell Renal Cell Carcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of Head and Neck | Colo-rectal Cancer | Transitional Cell Carcinoma of the Bladder | Other Solid Tumors

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Is Desmoplastic Stromal Reaction Useful to Modulate Lymph Node Dissection in Sporadic Medullary Thyroid Carcinoma? (DSR-MTC)

Medullary Thyroid Cancer | Lymph Node Disease | Lymph Node Metastasis | Medullary Carcinoma | Medullary Tumor | Medullary Neoplasms | Desmoplasia | Desmoplastic | Desmoplastic Reaction

Italy
Crinetics Pharmaceuticals Inc.

Active, not recruiting

Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome

Carcinoid Tumor | Carcinoid Syndrome | Carcinoid | Carcinoid Tumor of Ileum | Carcinoid Tumor of Cecum | Carcinoid Syndrome Diarrhea | Carcinoid Intestine Tumor | Carcinoid Tumor of Liver | Carcinoid Tumor of Pancreas

United States, Brazil, Argentina, Canada, Mexico, Peru, Poland
Exicure, Inc.

Terminated

Intratumoral Cavrotolimod Combined With Pembrolizumab or Cemiplimab in Patients With Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, or Other Advanced Solid Tumors

Advanced or Metastatic Solid Tumors | Advanced or Metastatic Merkel Cell Carcinoma | Advanced or Metastatic Cutaneous Squamous Cell Carcinoma | Advanced or Metastatic Melanoma | Advanced or Metastatic Head and Neck Squamous Cell Carcinoma

United States
University of Dundee

Completed

Appropriate Dosing to Optimise Personalised Cancer Treatments (ADOPT)

Ovarian Cancer | Lung Cancer, Non-small Cell | Melanoma Stage IV | Melanoma Stage III | Renal Cancer Stage III | Renal Cancer Stage IV

United Kingdom
University of Texas Southwestern Medical Center

Completed

Prospective Registry Trial for Single Port Robot-assisted Nipple Sparing Mastectomy (SPrNSM) (SPrNSM)

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
Celldex Therapeutics
Bristol-Myers Squibb

Completed

A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors

Squamous Cell Carcinoma of the Head and Neck (SCCHN) | Ovarian Carcinoma-Enrollment Completed | Colorectal Cancer (CRC)-Enrollment Completed | Renal Cell Carcinoma (RCC) (Phase ll Only) | Glioblastoma (GBM) (Phase ll Only)-Enrollment Completed

United States
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic Cholangiocarcinoma

Unresectable Extrahepatic Bile Duct Carcinoma | Recurrent Cholangiocarcinoma | Non-Resectable Cholangiocarcinoma | Stage III Intrahepatic Cholangiocarcinoma | Stage IIIA Hilar Cholangiocarcinoma | Stage IIIB Hilar Cholangiocarcinoma | Stage IVA Hilar Cholangiocarcinoma | Stage IVA Intrahepatic Cholangiocarcinoma and other conditions

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma | Cervical Small Cell Carcinoma | Stage IB Cervical Cancer | Stage IIA Cervical Cancer | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage IVA Cervical Cancer

United States

Clinical Trials on Gastrointestinal Adenocarcinomas

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