Clinical Trials on Gastrointestinal Reflux in United Kingdom

Total 7958 results

Norgine

Completed

A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting Conditions

Acid Reflux | Gastro Oesophageal Reflux Disease

United Kingdom
Imperial College London

Completed

Physical Activity and Gastrointestinal Investigations

Gastro-oesophageal Reflux Disease

United Kingdom
Institute of Child Health

Completed

Laparoscopy in Children: Does it Decrease the Metabolic, Endocrine and Inflammatory Stress Response to Surgery

Gastro-Oesophageal Reflux

United Kingdom
Midwest Biomedical Research Foundation
Kansas City Veteran Affairs Medical Center

Completed

Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study

Non-erosive Reflux Disease

United States, United Kingdom
King's College Hospital NHS Trust

Completed

Near Focus NBI-Driven Artificial Intelligence for the Diagnosis of Gastro-Oesophageal Reflux Disease

Gastro Esophageal Reflux

United Kingdom
Sanofi

Completed

Scintigraphy Study to Compare the Antireflux Activity of the Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects

Gastroesophageal Reflux Disease

United Kingdom
Oxford University Hospitals NHS Trust

Completed

Comparison of Laparoscopic Nissen Versus Thal Fundoplication in Children

Gastroesophageal Reflux Disease

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Manchester University NHS Foundation Trust

Completed

A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux

Gastro-oesophageal Reflux

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Reflux Oesophagitis

United Kingdom
The Functional Gut Clinic
Rosa Biotech

Recruiting

LPR Fluorescence Pilot

Gastro Esophageal Reflux | Laryngopharyngeal Reflux

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Takeda

Completed

TAK-438 - Safety, Blood Levels & Effects of Repeated Doses (TAK-438_107)

Gastroesophageal Reflux Disease (GERD) | Erosive Esophagitis(EE)

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Assessment of Gastro-esophageal Reflux Using Endo-Flip vs Bravo

Heartburn | Gastro-esophageal Reflux

United Kingdom
Imperial College London

Active, not recruiting

The Bacterial Composition of the Stomach in Reflux Disease

Gastric Cancer | Esophagitis | Gastro Esophageal Reflux | Barrett Esophagus | Oesophageal Cancer | GORD | Oesophageal Reflux | Oesophageal Carcinoma

United Kingdom
AstraZeneca

Completed

PPI Sequencing Study

Gastro-Oesophageal Reflux Disease

United Kingdom
Queen Mary University of London

Completed

The Effect of Autonomic Modulation on Symptoms in Patients With Reflux Hypersensitivity

Gastro Esophageal Reflux

United Kingdom
St George's, University of London
Wingate Institute of Neurogastroenterology

Recruiting

Gastro-intestinal Physiology After Anti-Reflux Procedures (GASP)

Gastroesophageal Reflux

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Physiological Predictors of Clinical Outcomes After Anti-reflux Surgery

Gastroesophageal Reflux

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Coordination Versus Pressure in Oesophageal Peristalsis

Gastroesophageal Reflux

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Oesophageal Acid Exposure in Healthy Subjects Over 96 Hours

Gastroesophageal Reflux

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Correlations Between Wireless pH Monitoring and Variation in Reflux Symptom Questionnaire, 7 Day Recall

Gastroesophageal Reflux

United Kingdom
EndoStim Inc.

Unknown

Effect of Long-Term Electrical Stimulation on LES Pressure and Esophageal Acid Exposure in Patients With GERD

Gastroesophageal Reflux Disease

Chile, Colombia, India, Mexico, Netherlands, New Zealand, United Kingdom
The Functional Gut Clinic

Recruiting

Gastric Neuromuscular Function in GERD

GERD

United Kingdom
Dr Anthony Hobson

Completed

Intestinal Adsorbent and Breath Gas Levels

Gastroesophageal Reflux | Small Intestinal Bacterial Overgrowth

United Kingdom
Shire

Terminated

An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients

Gastroesophageal Reflux Disease

United Kingdom, Switzerland, Netherlands, Belgium, France, Germany
Torax Medical Incorporated

Completed

Observational Study of Anti-Reflux Surgery

Gastroesophageal Reflux | Gastro Esophageal Reflux | GERD

Italy, Austria, Germany, United Kingdom
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD?

Gastroesophageal Reflux Disease | GERD | Acid Reflux | Reflux

United States
Vanderbilt University Medical Center

Completed

Assessment of Esophageal Epithelium Integrity With Mucosal Impedance

Gastroesophageal Reflux Disease (GERD) | Non-erosive Reflux Disease (NERD)

United States
University of Iowa

Withdrawn

Dexilant Treatment in Gastrointestinal Reflux Disease (GERD Related Non Cardiac Chest Pain (Dexilant)

Chest Pain | Gastrointestinal Reflux Disease

United States
LCMC Health

Terminated

Confocal Endomicroscopy for Non-Erosive Reflux Disease Detection (CENERDD)

Gastroesophageal Reflux | Non-erosive Reflux Disease

United States
EndoStim Inc.

Terminated

An Investigation of the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System for the Treatment of Reflux

Gastroesophageal Reflux | Reflux, Gastroesophageal | Gastroesophageal Reflux Disease (GERD) | Acid Reflux

United States, Belgium, Netherlands, United Kingdom
Vanderbilt University Medical Center
Amenity Health, Inc.

Terminated

Sleep Position May Reduce Acid Reflux Symptoms at Night

Extra-esophageal Reflux

United States
Medtronic Endovascular
VNUS Medical Technologies, A Covidien Company

Completed

ClosureFAST vs. Laser Ablation for the Treatment of GSV Disease: A Multicenter, Single-Blinded, Randomized Study. (RECOVERY)

Venous Reflux

United States
Aplos Medical
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Recruiting

Omega Cuff for GERD Feasibility Study

GERD, Acid Reflux, Treatment

United States
Mayo Clinic

Withdrawn

HRIM vs Mucosal Impedance in GERD Participants

Gastro-esophageal Reflux Disease (GERD)

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol (RESULT)

Gastroesophageal Reflux Disease (GERD) | Reflux

United States, Canada
University of Washington
Takeda Pharmaceuticals North America, Inc.

Withdrawn

Evaluating Treatment Response in Laryngo-Pharyngeal Reflux

Laryngo-pharyngeal Reflux

United States
Institute of Child Health

Completed

Clinical Outcome of Laparoscopic Versus Open Nissen Fundoplication in Children: 3-Year Follow-up Study of Randomized Controlled Trial.

Gastro -Oesophagal Reflux

United Kingdom
United States Naval Medical Center, Portsmouth

Unknown

Prospective Evaluation of Symptom Resolution in Acid Versus Non-acid Reflux Disease Following Anti-reflux Surgery

Non-acid Reflux Disease

United States
Brigham and Women's Hospital
EndoGastric Solutions

Not yet recruiting

Transoral Incisionless Fundoplication (TIF) for Laryngopharyngeal Reflux (LPR) Patients (TIF-LPR)

Gastroesophageal Reflux Disease (GERD) | Motility Disorder | Laryngopharyngeal Reflux (LPR) | Reflux Disease, Gastro-Esophageal

United States
Stanford University

Completed

Determination of Voiding Patterns of Children With Vesicoureteral Reflux

Vesicoureteral Reflux

United States
James J. Peters Veterans Affairs Medical Center

Unknown

GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals

Gastro Esophageal Reflux Disorder

United States
Ono Pharmaceutical Co. Ltd

Completed

A Study to Investigate the Effect of ONO-8539 on Acid-Induced Oesophageal Hypersensitivity in Healthy Volunteers

Acid Reflux

United Kingdom
Novartis

Completed

A Study to Assess the Efficacy, Safety and Tolerability of Tegaserod Alone and in Combination With Omeprazole Given Orally in Patients With Symptoms of Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroespohageal Reflux Disease

United States
AstraZeneca

Completed

Efficacy and Safety of Esomeprazole Once Daily for the Treatment of GERD in Neonatal Patients

GERD

Germany, United Kingdom, Australia
University of Cambridge

Completed

Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus (MuSE)

Esophageal Neoplasms | Barrett Esophagus | Reflux Esophagitis

United Kingdom
Connecticut Children's Medical Center

Completed

Prospective Pediatric Vesicoureteral Reflux Surgery Database

Vesicoureteral Reflux

United States
Boston Children's Hospital

Withdrawn

Study of Endoscopic Versus Open Surgery for Urinary Reflux (STRETCH)

Vesicoureteral Reflux

United States

Clinical Trials on Gastrointestinal Reflux in United Kingdom

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