Clinical Trials on Gastrointestinal Discomfort

Total 23275 results

City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Survivorship Care Planning in Patients With Colorectal or Non-Small Cell Lung Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon... and other conditions

United States
Duke University
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Patients With Metastatic Cancer

Testicular Germ Cell Tumor | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Metastatic Cancer | Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
M.D. Anderson Cancer Center

Completed

Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer

Sarcoma | Adenocarcinoma | Gastrointestinal Neoplasms | Ovarian Neoplasms | Peritoneal Neoplasms | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Adrenocortical Carcinoma | Desmoplastic Small Round Cell Tumor | Retroperitoneal Neoplasms

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); National Human Genome Research Institute (NHGRI)

Recruiting

Video Education With Result Dependent dIsclosure (VERDI)

Melanoma | Sarcoma | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Renal Cancer | Genetic Testing

United States
Seagen Inc.

Recruiting

A Study of SGN-PDL1V in Advanced Solid Tumors

Melanoma | Carcinoma, Non-Small-Cell Lung | Gastric Cancer | Ovarian Neoplasms | Squamous Cell Carcinoma of the Head and Neck | Triple Negative Breast Neoplasms | Esophageal Squamous Cell Carcinoma

United States, Spain, Italy, Canada, United Kingdom, France, Belgium, Germany, Netherlands
Merck Sharp & Dohme LLC

Recruiting

MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

Uterine Cervical Neoplasms | Stomach Neoplasms | Urinary Bladder Neoplasms | Hepatocellular Carcinoma | Esophageal Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Triple Negative Breast Neoplasms | Gallbladder Neoplasms

United States, Chile, Colombia, France, Germany, Israel, Italy, Japan, Korea, Republic of, Netherlands, Poland, Spain, Taiwan, Turkey, Canada
Arbeitsgemeinschaft medikamentoese Tumortherapie
Roche Pharma AG; AstraZeneca

Recruiting

Genomic Testing and Resulting Medical Decisions

Hematologic Neoplasms | Cancer Head Neck | Cancer, Breast | Cancer of Stomach | Cancer of Unknown Origin | Cancer Colorectal | Cancer, Lung | Cancer of Skin | Cancer of Esophagus | Cancer Refractory | Cancer, Bladder | Cancer, Uterus | Cancer Cervix | Cancer Liver | Cancer, Kidney

Austria
National Cancer Institute (NCI)

Recruiting

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Lynch Syndrome | Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Refractory Ependymoma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Refractory Diffuse Intrinsic Pontine Glioma | Recurrent Brain Neoplasm | Refractory Brain Neoplasm | Constitutional...

United States, Canada
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Active, not recruiting

Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage III Esophageal Adenocarcinoma AJCC v8 and other conditions

United States
MedImmune LLC

Completed

A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors

Metastatic Castration-resistant Prostate Cancer (mCRPC) | Small Cell Lung Cancer (SCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Head and Neck Squamous Cell Carcinoma (HNSCC) | Colorectal Cancer (CRC) | Non Small Cell Lung Cancer Squamous (NSCLC-Sq)

United States, Canada
Weill Medical College of Cornell University

Unknown

Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders

Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Cholangitis | Barrett's Esophagus | Gallstones | Choledocholithiasis | Bile Leak | Obstructive Jaundice | Duodenal Cancer | Pancreatic Pseudocysts | Ampullary Cancer | Biliary Strictures | Recurrent Pancreatitis | Bile Duct... and other conditions

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

SU006668 in Treating Patients With Advanced Solid Tumors

Kidney Cancer | Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Prostate Cancer | Multiple Myeloma and Plasma Cell Neoplasm
Nanfang Hospital, Southern Medical University

Recruiting

A Mucosal Contouring Method Based on Swallowing-induced Breakthrough Pain for Radiation-induced Oropharyngeal Mucositis

Radiation-induced Oropharyngeal Mucositis | Swallowing-induced Breakthrough Pain

China
Danone Specialized Nutrition

Recruiting

Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients

Cancer | Inflammatory Bowel Diseases | Malnutrition | Hiv | Chronic Obstructive Pulmonary Disease (COPD)

Spain
Celltrion HealthCare France

Recruiting

Yuflyma® (Adalimumab), Patient Experience After Switching (YU-MATTER)

Rheumatoid Arthritis | Crohn Disease | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylarthritis | Axial Spondyloarthritis Without Radiographic Evidence of Ankylosing Spondylitis

France
Seoul National University Boramae Hospital
Dong-A ST Co., Ltd.

Not yet recruiting

Compare the Effect of Eupatilin and Rebamipide on the Prevention of Gastroenteropathy (CEERS)

Osteoarthritis | Rheumatoid Arthritis | Enteritis | Gastric Ulcer | Ankylosing Spondylitis | Other Musculoskeletal Disorder | NSAID-Associated Gastropathy | NSAID (Non-Steroidal Anti-Inflammatory Drug) Induced Enteropathy
Linkoeping University

Recruiting

Idiopathic Normal Pressure Hydrocephalus: Focus on Imaging and Clinical Symptoms. (LiNPH)

Leukoencephalopathies | Fecal Incontinence With Fecal Urgency | Diffusion Tensor Imaging | Urine Incontinence

Sweden
University of British Columbia
Praxis Spinal Cord Institute

Recruiting

Motor & Autonomic Concomitant Health Improvements With Neuromodulation & Exercise Training: An SCI RCT (MACHINE)

Spinal Cord Injuries | Neurogenic Bowel | Neurogenic Bladder

Canada
University of California, San Diego
UCB Pharma; The Organization of Teratology Information Specialists

Recruiting

OTIS Autoimmune Diseases in Pregnancy Project

Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Psoriatic Arthritis | Ankylosing Spondylitis

United States
Takeda

Active, not recruiting

A Study of Surgical Interventions in Fistulizing Conditions

Fistula | Crohns Disease | Rectovaginal Fistula | Complex Perianal Fistula | Complex Cryptoglandular Fistula

United States, Netherlands, Belgium, Israel, Italy, United Kingdom, Czechia, Austria, Canada, France
Region Zealand

Completed

Admission Pattern Among Children With Gastro-intestinal Infections Before and During the Covid-19 Pandemic

Gastroenteritis | Infectious Disease | Dehydration in Children | COVID-19 Pandemic | Norovirus Infections | Rota Virus Gastroenteritis

Denmark
Fundació Institut de Recerca de l'Hospital de la...

Completed

Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome) (CANVAS)

Cough | Gastroesophageal Reflux | Cerebellar Ataxia

Spain
University of Aarhus
Center for Clinical Research and Prevention

Completed

Psychological Risk Factors for Functional Somatic Disorders

Irritable Bowel Syndrome | Fibromyalgia | Somatoform Disorders | Medically Unexplained Symptoms | Chronic Fatigue Syndrome | Bodily Distress Syndrome | Medically Unexplained Syndrome
Jonsson Comprehensive Cancer Center

Completed

Fluorine F 18 Clofarabine PET/CT in Imaging Patients With Autoimmune or Inflammatory Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Crohn Disease | Takayasu Arteritis | Autoimmune Disease | Inflammatory Disorder

United States
Acrotech Biopharma Inc.
Axis Clinicals Limited

Completed

Phase II Study of Folotyn With Leucovorin to Prevent/Reduce Mucositis in Patients With Hematological Malignancies

Refractory Peripheral T-Cell Lymphoma | Relapsed Peripheral T-Cell Lymphoma

United States
UCB BIOSCIENCES, Inc.
PPD; Parexel

Completed

A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Via the Placenta (CRIB)

Rheumatoid Arthritis | Crohn's Disease | Psoriatic Arthritis | Ankylosing Spondylitis | Axial Spondyloarthritis (AxSpA) | Non-radiographic Evidence-AxSpA

Netherlands, Switzerland, United States, France
OhioHealth
BTG International Inc.

Withdrawn

Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs

Leg Ulcer | Varicose Veins | Varicose Ulcer | Venous Leg Ulcer | Venous Reflux | Reflux | Venous Ulcer | Veins, Varicose | Varicose Veins Leg

United States
Janssen Biotech, Inc.
Merck Sharp & Dohme LLC

Completed

Analysis of Birth Outcomes of Swedish, Danish and Finnish Women Exposed to Remicade With Inflammatory Bowel Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Psoriasis

Inflammatory Bowel Disease
Jawaharlal Nehru Medical College

Completed

Primary Cecal Pathologies Presenting as Acute Abdomen

Laparotomy | Acute Abdomen | Emergency Surgery | Amoebic Colitis | Diverticulitis of Caecum | Typhlitis
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Effects of Non-Nutritive Sucking on Gastroesophageal Reflux and Related Apneas in Symptomatic Preterm Infants (NNS-GER-SO)

Gastroesophageal Reflux | Bradycardia | Apneas

Italy
Walter Reed Army Medical Center

Unknown

Comparison of Biofeedback vs. Botox Injection to Treat Levator Ani Syndrome

Levator Ani Syndrome With Pain and/or Constipation Symptoms.

United States
Nanfang Hospital, Southern Medical University

Recruiting

A Real-world Observational Study of a Mucosal Contouring Method for Radiation-induced Oropharyngeal Mucositis

Radiation-induced Oropharyngeal Mucositis | Swallowing-induced Breakthrough Pain

China
Vedanta Biosciences, Inc.

Recruiting

VE303 for Prevention of Recurrent Clostridioides Difficile Infection (RESTORATiVE303)

Clostridium Difficile Infection Recurrence | Recurrent Clostridium Difficile Infection | Clostridium Difficile | Diarrhea Infectious | CDI | Clostridium Difficile Infections | Clostridioides Difficile Infection | C.Difficile Diarrhea | Clostridioides Difficile Infection Recurrence | C. Diff Infection

United States
Harran University
Hasan Kalyoncu University

Not yet recruiting

The Effect of Probiotics Added to the Mother's Diet on Preterm Babies

Necrotizing Enterocolitis | Breast Milk Expression | Preterm | Late-Onset Neonatal Sepsis
University of Thessaly
Larissa University Hospital; IASO Thessalias

Recruiting

Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes

Pancreas Cancer | PROMs | Delayed Gastric Emptying | Surgery-Complications | ERAS | Pancreatic Hemorrhage | Pancreas; Fistula

Greece
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Recruiting

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

Gastrointestinal Diseases | Heart Failure | Infections | Urologic Diseases | Shock | Hematologic Diseases | Critical Illness | Rheumatic Diseases | Asthma | Renal Failure | Neurologic Disorder | COPD Exacerbation | Cardiac Event | Oncology Problem | Arrythmia | Renal Disease

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis

Chronic Granulomatous Disease-associated Colitis

United States
University of Alabama at Birmingham

Recruiting

Topical Vaginal Estrogen for Postpartum Obstetric Anal Sphincter Injury Recovery

Urinary Incontinence | Sexual Dysfunction | Anal Incontinence | Obstetric; Injury Pelvic Floor

United States
Helsinki University Central Hospital

Recruiting

Patient-reported Outcome Measures (PROMs) in Patients With Bodily Stress Syndrome: Protocol for a Prospective Cohort Study (SYMPA)

Fatigue | Irritable Bowel Syndrome | Fibromyalgia | Dysphagia | Chronic Fatigue Syndrome | Somatic Symptom | Exhaustion; Syndrome

Finland
Centre Hospitalier Universitaire de Besancon

Recruiting

Evolution and Treatments of Chronic Inflammatory Systemic Diseases (MISTIC)

Arthritis, Rheumatoid | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Psoriatic Arthritis | Spondyloarthritis | Verneuil's Disease

France
MitoImmune Therapeutics

Active, not recruiting

Evaluate the Safety and Efficacy for Oral Mucositis Prevention of MIT-001 in Auto HSCT (Capella)

Lymphoma | Multiple Myeloma | Oral Mucositis | Hematologic Cancer

Korea, Republic of
Zeng Changhao
The First Affiliated Hospital of Zhengzhou University

Completed

Stellate Ganglion Block in Patients With Cerebral Small Vessel Disease

Cognitive Impairment | Dysphagia | Cerebral Small Vessel Diseases

Taiwan
University of Alcala

Completed

Effectiveness of Hypopressive Exercises Versus Pelvic-perineal Physiotherapy (HEPFD)

Urinary Incontinence | Pelvic Pain | Pelvic Floor Disorders | Fecal Incontinence

Spain
National Institute of Allergy and Infectious Diseases...

Enrolling by invitation

Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous Disease

Chronic Granulomatous Disease | Inflammatory Bowel Disease

United States
Universiti Kebangsaan Malaysia Medical Centre

Completed

Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements

Ovarian Cysts | Appendicitis | Cholelithiases

Malaysia
Poitiers University Hospital
Agence Nationale de sécurité du Médicament

Active, not recruiting

Materiovigilance After Urinary Incontinence or Prolapse Surgery (VIGI-MESH)

Pelvic Organ Prolapse | Urinary Stress Incontinence | Rectal Prolapse

France
UCB Biopharma SRL

Completed

A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) (CHERISH)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn's Disease | Psoriatic Arthritis | Axial Spondyloarthritis

United States, France, Germany, Spain, Switzerland, Netherlands
NorthShore University HealthSystem
University of Chicago; The Gerber Foundation; Fundacion Para La Investigacion...

Completed

Oropharyngeal Administration of Mother's Colostrum for Premature Infants (NS-72393-360)

Enterocolitis, Necrotizing | Infection | Ventilator-associated Pneumonia

United States
Omri Schwarztuch Gildor

Enrolling by invitation

Sacral Neuromodulation in Neurogenic Patients

Overactive Bladder | Neurogenic Bowel | Fecal Incontinence | Urge Incontinence | Neurogenic Bladder | Retention, Urinary

Israel
University of Aarhus
Center for Clinical Research and Prevention

Completed

Welfare Benefits in Functional Somatic Disorders

Irritable Bowel Syndrome | Fibromyalgia | Somatoform Disorders | Medically Unexplained Symptoms | Chronic Fatigue Syndrome | Bodily Distress Syndrome | Medically Unexplained Syndrome

Clinical Trials on Gastrointestinal Discomfort

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Jamaica

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Rare Diseases

Drug Interventions

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