Clinical Trials on Genes, BRCA 1
Total 6427 results
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Atossa Therapeutics, Inc.WithdrawnBreast Cancer, Preneoplastic Conditions, BRCAIsrael
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Memorial Sloan Kettering Cancer CenterActive, not recruitingScreening Breast MRI in Patients Who Are BRCA Mutation CarriersUnited States
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European Institute of OncologyRecruitingBRCA1 Mutation | BRCA2 Mutation | Lobular Breast Carcinoma | Lobular in Situ Breast CarcinomaItaly
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University of PennsylvaniaInovio PharmaceuticalsRecruiting
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Institute of Cancer Research, United KingdomRoyal Marsden NHS Foundation Trust; Cancer Research UK; Ronald and Rita McAulay...Active, not recruitingProstate Cancer in BRCA1 and BRCA2 CarriersUnited Kingdom
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The Netherlands Cancer InstituteRadboud University Medical Center; Erasmus Medical Center; Dutch Cancer SocietyUnknownCardiovascular Diseases | Quality of Life | Cognitive Decline | BRCA1 Mutation | BRCA2 Mutation | Bone Mineral Density | Surgical Menopause | Menopause SurgicalNetherlands
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Centre Leon BerardRecruitingCancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditionsFrance, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditionsUnited States
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Aspira Women's HealthTerminatedHereditary Breast and Ovarian Cancer | Adnexal Mass | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationUnited States
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Memorial Sloan Kettering Cancer CenterPhenogen SciencesRecruitingGenetic Testing | BRCA1/2United States
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Radboud University Medical CenterUnknown
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BioMed Valley Discoveries, IncTerminatedAdvanced Solid Tumor | MAP2K1 Gene Mutation | BRAF Gene Mutation | MEK Mutation | BRAF Gene Alteration | MEK Alteration | MAP2K1 Gene Alteration | MAP2K2 Gene Mutation | MAP2K2 Gene AlterationUnited States
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VA Office of Research and DevelopmentRecruitingMetastatic Castrate Resistant Prostate Cancer | BARD1, BRCA1, BRCA2, BRIP1, CHEK1, FANCL, PALB2 | RAD51B, RAD51C, RAD51D, or RAD54L MutationsUnited States
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Leiden University Medical CenterUniversity Medical Center Groningen; Erasmus Medical CenterRecruitingBRCA1 Mutation | BRCA2 Mutation | Homologous Recombination Deficiency | Ovarian Neoplasm EpithelialNetherlands
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | KRAS Gene Mutation | Metastatic Malignant Solid Neoplasm | EGFR Gene Mutation | ERBB2 Gene Amplification | ERBB2 Gene Mutation | EGFR Gene Amplification | ERBB3 Gene Mutation | ERBB4 Gene MutationUnited States
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Georgetown UniversityNational Cancer Institute (NCI); National Human Genome Research Institute (NHGRI)CompletedBreast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2)United States
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Tango Therapeutics, Inc.TerminatedBreast Cancer | Ovarian Cancer | Prostate Cancer | Pancreas Cancer | BRCA1 Mutation | BRCA-Mutated Ovarian Carcinoma | BRCA-Associated Breast Carcinoma | HRD Positive Advanced Ovarian CancerUnited States
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Women and Infants Hospital of Rhode IslandCompletedOvarian Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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University of Alabama at BirminghamNational Cancer Institute (NCI)WithdrawnOvarian Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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University of ArizonaNational Cancer Institute (NCI)CompletedOvarian Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingOvarian Cancer | Ultrasound Therapy; Complications | BRCA MutationItaly
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Mayo ClinicRecruitingCancer | Cancer Gene Mutation | PAN Gene MutationUnited States
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AbbVieCompletedOncology | High Grade Serous Ovarian Cancer | BRCA Mutated | BRCA Mutated Breast Cancer
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Intergroupe Francophone de Cancerologie ThoraciquePfizerCompletedALK Gene Rearrangement Positive | Non-small Cell Lung Cancer Metastatic | ROS-1 Gene Rearrangement PositiveFrance
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Sidney Kimmel Comprehensive Cancer Center at Johns...Bristol-Myers Squibb; Vanderbilt University; Avon Breast Health Access FundActive, not recruitingMetastatic Solid Tumor | SF3B1 Gene Mutation | Spliceosome Mutation | U2AF1 Gene Mutation | SRSF2 Gene MutationUnited States
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AstraZenecaCompletedOvarian Neoplasms | BRCA1 Protein | BRCA2 ProteinNetherlands, Belgium, United Kingdom, Poland
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National Cancer Institute (NCI)NRG OncologyCompletedRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier | Ovarian Epithelial TumorUnited States
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SWOG Cancer Research NetworkNational Cancer Institute (NCI)Active, not recruitingStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Lung Non-Small Cell Squamous Carcinoma | Recurrent Lung Non-Small Cell Carcinoma | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene Mutation | Recurrent Lung Adenocarcinoma | Loss of Heterozygosity | Recurrent... and other conditionsUnited States
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Rutgers, The State University of New JerseyNational Cancer Institute (NCI)RecruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Ovarian Carcinoma | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC... and other conditionsUnited States
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Peking University Third HospitalRecruiting
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Peking University People's HospitalJiangsu Hengrui Pharmaceutical Co., Ltd.Enrolling by invitationGermline BRCA-mutated HER2-negative Breast CancerChina
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Institut für Klinische Krebsforschung IKF GmbH...Incyte Biosciences International SàrlRecruitingIntrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Gene Translocation | FGFR2 Gene RearrangementGermany
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Relay Therapeutics, Inc.Active, not recruitingCholangiocarcinoma | Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Amplification | FGFR2 Gene Fusion/Rearrangement | FGFR2 Gene Translocation | FGFR2 Gene Activation | Other Solid Tumors, AdultUnited States, France, Italy, United Kingdom, Korea, Republic of, Spain, Taiwan, Sweden, Germany, Netherlands, Singapore, Australia, Hong Kong
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Samsung Medical CenterAstraZenecaCompletedTo Investigate the Prevalence of BRCA 1/2 Mutation Among Ovarian Cancer
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Azienda Socio Sanitaria Territoriale degli Spedali...RecruitingSexual Dysfunction | Sexual Dysfunctions, Psychological | Sexual Dysfunction, Physiological | BRCA MutationItaly
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Catholic University of the Sacred HeartUnknownBRCA1 and BRCA2 Mutation Carrier and BRCAness PhenotypeItaly
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The Cleveland ClinicNational Cancer Institute (NCI)CompletedBreast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2)
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Massachusetts General HospitalRecruitingLynch Syndrome | Genetic Predisposition to Disease | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Neoplasm | ATM Gene Mutation | MMR MutationUnited States
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858 Therapeutics, Inc.RecruitingBreast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Advanced or Metastatic Solid Tumors | ER+ Breast Cancer | Castrate Resistant Prostate Cancer | BRCA MutationUnited States
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Flint Rehabilitation Devices, LLCUniversity of TexasCompleted
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University of VirginiaActive, not recruitingReal-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies (Lung001)Lung Cancer | ALK Gene Mutation | MET Gene Mutation | KRAS Mutation-Related Tumors | RET Gene Mutation | EGFR Gene Mutation | EGFR | ROS1 Gene Mutation | BRAFUnited States
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University of Colorado, DenverRecruitingNon-Small Cell Lung Cancer | ALK Gene Mutation | EGFR Gene Mutation | BRAF V600E | Non-Small Cell Carcinoma of Lung, TNM Stage 4 | ROSE Cluster 1United States
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Galderma R&DCompletedGene ExpressionUnited States
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University of California, Los AngelesCompleted
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Tianjin Medical University Second HospitalRecruitingSolid Tumor | FGF Receptor Gene Mutation | FGF Amplification | FGF Receptor Gene Family Rearrangement | FGF Receptor Gene TranslocationChina
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Hamad Medical CorporationQatar UniversityCompleted
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Columbia UniversityRecruitingCancer | Insulin Resistance | MTOR Gene Mutation | PI3K Gene Mutation | AKT Gene MutationUnited States
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Pamela MunsterQuantumLeap Healthcare CollaborativeTerminatedTriple Negative Metastatic Breast Cancer | BRCA-mutated Solid TumorUnited States
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University Health Network, TorontoBayer; AstraZeneca; Amgen; AnHeart Therapeutics Inc.; Applied Health Research Centre and other collaboratorsRecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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City of Hope Medical CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Syndrome | BRCA2 Syndrome | No Evidence of Disease | Hereditary Ovarian Carcinoma | Hereditary Female Breast CarcinomaUnited States