Clinical Trials on Genetic Disorder

Total 150426 results

Tianjin First Central Hospital

Not yet recruiting

Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients (EDPARDSLDLTR)

Desflurane | Biliary Atresia | Pediatric Acute Respiratory Distress Syndrome

China
Medical College of Wisconsin
National Institute on Minority Health and Health Disparities (NIMHD)

Recruiting

Mixed-Methods Study of Multidimensional Adversity in Inner-City African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Diabetic Nephropathy Type 2 - Uncontrolled

United States
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Research Motor... and other collaborators

Recruiting

Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis (MotorMarker)

ALS (Amyotrophic Lateral Sclerosis) | Postpoliomyelitis Syndrome | Spinal Muscular Atrophy

Ireland
Croatian Society for Organ Support
Clinical Hospital Centre Zagreb

Recruiting

European Registry for Hemadsorption in Sepsis With the Seraph Filter

Sepsis | Systemic Inflammatory Response Syndrome | Disease | Critical Illness | Acute Respiratory Distress Syndrome | Multi Organ Failure | Infections - Pathogen Unspecified

Croatia
Maastricht University Medical Center

Recruiting

Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck Region

Quality of Life | Satisfaction, Patient | Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of Head and Neck | Skin Cancer | Squamous Cell Carcinomas | Squamous Cell Carcinoma of the Skin | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Cutaneous Squamous Cell Carcinoma | High-Risk Cancer

Netherlands
Nova Scotia Health Authority
Dalhousie University

Recruiting

Prehabilitation for Ovarian Cancer Patients

Ovarian Cancer | Frailty | Exercise | Enhanced Recovery After Surgery | Surgical Complication | Prehabilitation | Treatment Outcomes

Canada
Academisch Medisch Centrum - Universiteit van Amsterdam...
Patient-Led Research Collaborative Long COVID

Recruiting

Skeletal Muscle in PASC and ME/CFS Patients (MUSCLE-PASC)

ME/CFS | LONG-COVID | Post-acute Sequelae of COVID-19

Netherlands
K-Group, Beta, Inc., a wholly owned subsidiary...

Recruiting

A Study of ZN-c3 and Niraparib in Subjects With Platinum-Resistant Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Primary Peritoneal Carcinoma

United States, France
Karolinska University Hospital

Recruiting

PET Imaging of Solid Tumors by a Novel Tracer, 68Ga-FAPI

Stomach Neoplasms | Pancreatic Neoplasms | Epithelial Ovarian Cancer | Bile Duct Neoplasms

Sweden
iOMEDICO AG

Recruiting

Registry Platform Ovarian and Endometrial Cancer (SMARAGD)

Carcinoma | Ovarian Cancer | Endometrial Neoplasms | Endometrial Cancer | Ovary Neoplasm | Neoplasm, Ovarian | Carcinoma, Ovarian

Germany
Haider Mahdi
Pfizer; Zenith Epigenetics

Recruiting

ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States
Sheikh Zayed Medical College

Recruiting

Efficacy of Nebulized Lidocaine, Salbutamol, and Beclomethasone Plus Salbutamol in the Covid-19 Patients With ARDS on Non-invasive Ventilation; Randomized Control Trial

COVID-19 Acute Respiratory Distress Syndrome

Pakistan
Mongi Slim Hospital

Not yet recruiting

Macintosh Versus Macgrath for Laryngoscopy in COVID 19 Hypoxemic ICU Patients

COVID-19 Acute Respiratory Distress Syndrome
Maimónides Biomedical Research Institute of Córdoba

Recruiting

Prevention and Treatment With Hydroxychloroquine + Azithromycin of Acute Respiratory Syndrome Induced by COVID-19 (AMBUCOV)

Covid19 | Acute Respiratory Distress Syndrome

Spain
Hospital Universitario Infanta Leonor
Kern Pharma, S.L.; Fundación para la Investigación e Innovación Biomédica del...

Recruiting

DEXamethasone EARLY Administration in Hospitalized Patients With Covid-19 Pneumonia (EARLYDEXCoV2)

COVID-19 | Pneumonia, Viral | Acute Respiratory Distress Syndrome

Spain
Daiichi Sankyo, Inc.

Recruiting

A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors

Renal Cell Carcinoma | Ovarian Tumor

Japan, United States
Bobbie Jo Rimel, MD

Recruiting

Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer

Recurrent Ovarian Cancer | Platinum-sensitive Ovarian Cancer

United States
Baylx Inc.

Not yet recruiting

Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS

COVID-19 | Acute Respiratory Distress Syndrome | ARDS
Omar Aljitawi

Recruiting

Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Atypical Chronic Myeloid Leukemia | Chronic Monocytic Leukemia

United States
Sun Yat-sen University
Shenzhen Nanshan Center for Chronic Disease Control

Recruiting

Nanshan Elderly Cohort Study (NECS)

Cardiovascular Diseases | Stroke | Hypertension | Obesity | Cancer | Type 2 Diabetes Mellitus | Death | Metabolic Syndrome | Chronic Kidney Disease | Sarcopenia

China
Massachusetts General Hospital

Recruiting

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

Respiratory Distress Syndrome | Mechanical Ventilation Complication | Right Ventricular Dysfunction | ARDS, Human | Right Heart Failure | Lung Injury, Acute | Alveolar Edema

United States
University Hospital, Toulouse

Recruiting

Alveolar Recruitment Maneuvers, Intracerebral Hemodynamic and Oxygenation (M'RHICO)

Acute Respiratory Distress Syndrome (ARDS) | Cerebral Injuries

France
Imunon

Active, not recruiting

Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2) (OVATION 2)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States, Canada
Pfizer

Terminated

Study of Maplirpacept (PF-07901801) in Combination With PLD in Patients With Platinum-Resistant Ovarian Cancer

Ovarian Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Epithelial Ovarian Cancer | Ovarian Carcinoma | Primary Peritoneal Carcinoma

United States
University of Texas Southwestern Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Improving Chronic Disease Management With Pieces (ICD-Pieces)

Hypertension | Diabetes | Type 2 Diabetes | Chronic Kidney Disease | High BP

United States
The Hospital for Sick Children
University of Alberta; University of Waterloo

Terminated

Metformin Treatment in Infants After Perinatal Brain Injury

Premature Birth | Hypoxic Ischemic Encephalopathy of Newborn

Canada
Yale University
R-Pharm-US, LLC

Completed

Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States
Peking University
National Natural Science Foundation of China

Active, not recruiting

Peking University Birth Cohort in Tongzhou (PKUBC-T)

Obesity | Anemia | Preterm Birth | Child Development | Gestational Diabetes | Mother-Infant Interaction | Gestational Hypertension | Pregnancy Outcomes | Health Problems in Pregnancy

China
Children's Hospital Medical Center, Cincinnati

Completed

Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients

Thrombotic Microangiopathies | Atypical Hemolytic Uremic Syndrome | Multiple Organ Dysfunction Syndrome

United States
Peter MacCallum Cancer Centre, Australia

Active, not recruiting

BEACON - ABC in Recurrent Platinum Resistant HGSOC (BEACON)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma

Australia
AstraZeneca
British Columbia Cancer Agency

Completed

Phase II Study of AZD2281 in Patients With Known BRCA Mutation Status or Recurrent High Grade Ovarian Cancer or Patients With Known BRCA Mutation Status/ Triple Neg Breast Cancer

Breast Cancer | Ovarian Carcinoma

Canada
Sandoz

Completed

A Crossover Bioequivalence Study of Olaparib Tablets, 150 mg (Lek Pharmaceuticals d.d.) and Lynparza® (Olaparib) Tablets 150 mg (AstraZeneca Pharmaceuticals LP), in Patients With BRCA Mutated Ovarian Cancer, Recurrent Ovarian Cancer or Metastatic Breast Cancer

Breast Cancer | Ovarian Cancer

India
Peking Union Medical College Hospital

Completed

Single-cell Landscape of BALF in Patients With Severe ARDS and CARDS

Covid19 | ARDS: Acute Respiratory Distress Syndrome

China
Gregory Yanik
Jazz Pharmaceuticals

Completed

Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS)

COVID-19 | COVID | Acute Respiratory Distress Syndrome | Sars-CoV2

United States
Winthrop University Hospital

Withdrawn

Differential Characteristics of Neuropathy in Type 2 Diabetics With and Without Lower Extremity Wounds

Type 2 Diabetes | Diabetic Foot Ulcer | Diabetic Neuropathy

United States
University of Utah

Completed

Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit

Post-operative Craniotomy Patients | Carotid Endarterectomy and Carotid Artery Stenosis Patients | Post-op Spine Patients Admitted to the NCCU | Endovascular Patients Undergoing Intracranial Intervention | Traumatic Brain Injuries NPO for at Least 12 Hours

United States
Karolinska Institutet
University of California, San Diego; The Swedish Research Council; University... and other collaborators

Terminated

Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19 (COVID-19-HBO)

COVID-19 | Cytokine Storm | SARS (Severe Acute Respiratory Syndrome) | Acute Respiratory Failure | ARDS, Human | Sars-CoV2

Sweden, Germany
Genelux Corporation

Completed

GL-ONC1 Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Carcinomatosis

United States
Ward Photonics LLC

Terminated

Low-Level Laser Therapy Treatment of Lung Inflammation in Post-COVID-19 Recovery

COVID-19 | Acute Respiratory Distress Syndrome

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Completed

Efficacy of Respiratory Physiotherapy on Severe ICU-admitted COVID-19 Patients.

COVID-19 Acute Respiratory Distress Syndrome

Italy
Teodoro Marcianò

Terminated

Risk Factors for COVID-19 Mortality (RF-COVID)

Acute Respiratory Distress Syndrome | COVID-19 Virus Infection | Population at Risk

Italy
ExcellaBio LLC

Terminated

Combination of Nivolumab and Ipilimumab in Breast, Ovarian and Gastric Cancer Patients

Gastric Cancer | Ovarian Cancer | Breast Cancer Female

United States
Istanbul University - Cerrahpasa (IUC)

Withdrawn

Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients

Covid19 | Respiratory Distress Syndrome, Adult | Pulmonary Edema | Ventilation Perfusion Mismatch

Turkey
Unidad Temporal COVID-19 en Centro Citibanamex

Completed

Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2 (COVID-19)

Acute Respiratory Distress Syndrome | SARS-CoV-2 Acute Respiratory Disease | Hypoxemia | Hypoxic Pulmonary Vasoconstriction

Mexico
University of Zurich

Completed

Closed Loop Mechanical Ventilation and ECMO

Acute Respiratory Distress Syndrome | Cardiogenic Shock
University of Maryland, Baltimore

Withdrawn

Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS (CHILL-pilot)

Respiratory Distress Syndrome, Adult | Sars-CoV2

United States
University Hospital, Tours

Completed

Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 (HIGH-PRONE-COVID-19)

COVID-19 | Acute Respiratory Distress Syndrome

France
University Hospital, Montpellier

Completed

Extra Vascular Lung Water and Pulmonary Permeability in Critically Ill Patients With SARS-CoV-2 (COVID-19) (PiCCOVID)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome

France
Spectrum Pharmaceuticals, Inc

Completed

Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumors

Small Cell Lung Cancer | Ovarian Cancer | Solid Tumors

United States
Assiut University

Unknown

Neuromuscular Ultrasound in Correlation to Neurophysiological Findings

Diabetic Neuropathies | Carpal Tunnel Syndrome | Guillain-Barre Syndrome

Clinical Trials on Genetic Disorder

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