Clinical Trials on Genetic High Risk for Schizophrenia in Switzerland

Total 330 results

DePuy International

Completed

Postmarketing Study to Determine Performance of the SIGMA HP® PARTIAL KNEE SYSTEM

Osteoarthritis | Post-traumatic Arthritis | Gout | Pseudo-gout

Switzerland, Italy
University of Zurich

Recruiting

Exophthalmometry With 3D Face Scanners (EX3D)

Graves Ophthalmopathy | Exophthalmos | Orbital Fractures | Orbital Tumor

Switzerland
University of Geneva, Switzerland

Terminated

Neuroprotective Effects of Risperdal on Brain and Cognition in 22q11 Deletion Syndrome

22q11.2 Deletion Syndrome

Switzerland
University of Geneva, Switzerland

Completed

Effects of Methylphenidate on Brain and Cognition in 22q11 Deletion Syndrome

22q11.2 Deletion Syndrome

Switzerland
Julius-Maximilians University
Hannover Medical School; Goethe University; Triemli Hospital; Mukoviszidose eV... and other collaborators

Completed

Effects of a 6-Months Physical Conditioning Program in Patients With Cystic Fibrosis

Cystic Fibrosis

Germany, Switzerland
Centre Hospitalier Universitaire Vaudois
University of Lausanne

Completed

Health Needs of Patients With Kallmann Syndrome

Kallmann Syndrome | Idiopathic Hypogonadotropic Hypogonadism | Congenital Hypogonadotropic Hypogonadism

Switzerland
University Hospital, Basel, Switzerland

Completed

Acquired Von Willebrand Syndrome in Severe Aortic Stenosis

Bleeding | Aortic Stenosis | Von Willebrand Disease

Switzerland
Stephan Eliez

Recruiting

Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome

tACS | 22Q11 Deletion Syndrome

Switzerland
Georgios Papadakis

Recruiting

Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome (KLIN-HEALTH)

Klinefelter Syndrome

Switzerland
Novartis

Completed

Efficacy and Safety of Lumiracoxib 400 mg Once Daily in Acute Flares of Gout

Acute Gouty Arthritis

Germany, Switzerland
University of Bern
Centre Hospitalier Intercommunal Creteil; Hacettepe University; Universitaire... and other collaborators

Recruiting

The Ear-Nose-Throat (ENT) Prospective International Cohort of PCD Patients (EPIC-PCD) (EPIC-PCD)

Primary Ciliary Dyskinesia | Kartagener Syndrome

Switzerland
University of Bern

Recruiting

Swiss Primary Ciliary Dyskinesia Registry (CH-PCD)

Primary Ciliary Dyskinesia | Kartagener Syndrome

Switzerland
Swiss Federal Institute of Technology

Completed

Evaluation of a Textile Scapula Orthosis (ScapOrthosis)

Muscle Weakness | Muscular Dystrophies | Muscular Dystrophy | Muscular Dystrophy, Facioscapulohumeral | Scapular Dyskinesis | Muscular Weakness

Germany, Switzerland
University of Bern
Hacettepe University; Oslo University Hospital; Hannover Medical School; Swiss... and other collaborators

Recruiting

International Primary Ciliary Dyskinesia Cohort (iPCD)

Primary Ciliary Dyskinesia | Kartagener Syndrome

Switzerland
Angelo Auricchio

Terminated

Validation Of A New S-ICD Algorithm To Reduce Oversensing Of Dynamic T-Waves In Patients With Brugada Syndrome (DE-08-16)

Brugada Syndrome 1S

Belgium, Italy, Switzerland
Nelly Pitteloud

Recruiting

GnRH Therapy on Cognition in Down Syndrome

Down Syndrome | Cognitive Decline | Alzheimer Disease, Early Onset | Olfaction Disorders

Switzerland
University Hospital, Basel, Switzerland

Enrolling by invitation

Spinal Cord Gray Matter Imaging in Spinal Muscular Atrophy

Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy Type III

Switzerland
University of Lausanne
University of Modena and Reggio Emilia

Completed

Sialic Acid Supplementation in N-Acetylneuraminic Acid Synthase (NANS) Deficiency

N-Acetylneuraminic Acid Storage Disease

Switzerland, Italy
Christian Baumann
ETH Zurich

Recruiting

Assessing the Symptomatic Benefit of Acoustic Slow Wave Enhancement in Parkinson Disease

Parkinson Disease | Mild Cognitive Impairment | Huntington Disease

Switzerland
University Hospital Inselspital, Berne

Recruiting

MRI-markers to Monitor Small Vessel Disease Dynamics in the Prognosis of Small Vessel Disease-associated, Cerebrovascular Events (MRI-PRO-SVD)

Cerebral Small Vessel Diseases | Intracerebral Hemorrhage | CAA - Cerebral Amyloid Angiopathy

Switzerland
University Hospital, Geneva
Swiss Hemophilia Network

Completed

Pregnancy and Fibrinogen Disorders (FIBRINOGEST)

Hypofibrinogenemia, Congenital | Afibrinogenemia, Congenital | Dysfibrinogenemia, Congenital

Switzerland, France, Slovakia
University Hospital, Basel, Switzerland

Completed

Tamoxifen in Duchenne Muscular Dystrophy (TAMDMD)

Duchenne Muscular Dystrophy

France, Spain, Germany, Netherlands, Switzerland, United Kingdom
Cantonal Hospital Graubuenden
University of Zurich

Not yet recruiting

Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease (SIDIA)

Autosomal Dominant Polycystic Kidney Disease

Switzerland
PTC Therapeutics
Genzyme, a Sanofi Company

Terminated

Ataluren for Nonsense Mutation Methylmalonic Acidemia

Amino Acid Metabolism, Inborn Errors

France, United Kingdom, Italy, Belgium, Germany, Switzerland
Genzyme, a Sanofi Company

Completed

An Open-label Extension Study of an Investigational Drug, Fitusiran, in Patients With Moderate or Severe Hemophilia A or B

Hemophilia A | Hemophilia B

Bulgaria, United States, United Kingdom, Russian Federation, Switzerland
Bayer

Completed

International PMS Study - KOGENATE Bayer

Hemophilia A

Switzerland, France, Spain, Sweden, Austria, Italy, Belgium, Denmark, Greece, Netherlands
Sanofi

Completed

A Phase 1 Study of an Investigational Drug, ALN-AT3SC, in Healthy Volunteers and Hemophilia A or B Patients

Hemophilia A | Hemophilia B

Bulgaria, Switzerland, United Kingdom, United States, Russian Federation
University of Bern
University Hospital Inselspital, Berne; University of Lausanne Hospitals; University... and other collaborators

Recruiting

Swiss Registry for Neuromuscular Disorders (Swiss-Reg-NMD)

Congenital Muscular Dystrophy | SMA | DMD | BMD | IMD

Switzerland
University Hospital Inselspital, Berne

Recruiting

Prognosis of Cerebral Small Vessel Disease - a Prospective Cohort Study (PRO-SVD)

Cerebral Amyloid Angiopathy | Cadasil | Small Vessel Cerebrovascular Disease | CAA - Cerebral Amyloid Angiopathy

Switzerland
University of Basel
Kantonsspital Aarau

Completed

Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical Conditions

Pheochromocytoma | Adrenal Tumor | Adrenal Mass | Adrenal Hyperplasia | Adrenal Metastases | Conn Adenoma

Switzerland
Astellas Pharma Inc

Completed

Treatment and Control of Atopic Dermatitis With 0.1% Tacrolimus Ointment

Dermatitis, Atopic

France, Germany, Spain, Belgium, Netherlands, Finland, Austria, United Kingdom, Italy, Czech Republic, Switzerland, Portugal, Denmark
University of Zurich

Unknown

Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases (NEUTROGENE)

Pustular Psoriasis | Erosive Pustular Dermatosis of the Scalp | Behcet's Disease | Dermatitis Herpetiformis | Pyoderma Gangrenosum | Linear IgA Bullous Dermatosis | Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue | Sweet's Syndrome | Bowel-associated Dermatosis-arthritis Syndrome | Acute Generalized Exanthematous Pustulosis and other conditions

Switzerland
Centre Hospitalier Universitaire Vaudois
Swiss National Science Foundation

Recruiting

Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate

Kallmann Syndrome | Hypogonadotropic Hypogonadism | Hypothalamic Amenorrhea | Polycystic Ovarian Syndrome | Precocious Puberty | Cleft Lip and Palate | Cleft Palate | Cleft Lip

Switzerland
Novartis

Completed

Efficacy and Safety of a Single Dose of Canakinumab (ACZ885) in Hospitalized Patients With Acute Gout

Arthritis, Gouty

United States, Switzerland, United Kingdom
Bayer

Recruiting

A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke (OCEANIC-STROKE)

Acute Non-cardioembolic Ischemic Stroke | Prevention of Ischemic Stroke | High-risk Transient Ischemic Attack

United States, Switzerland, Belgium, Sweden, Canada, Australia, Taiwan, Spain, Korea, Republic of, Latvia, Israel, Malaysia, Greece, Japan, Turkey, Netherlands, Romania, China, United Kingdom, Portugal, Italy, France, Slovakia, Austria, Czechi... and more
Second Sight Medical Products
National Eye Institute (NEI)

Completed

Argus® II Retinal Stimulation System Feasibility Protocol

Retinitis Pigmentosa

United States, United Kingdom, France, Mexico, Switzerland
CSL Behring

Completed

Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (EU Extension Study)

Primary Immunodeficiency (PID)

Poland, Germany, France, Romania, Spain, Sweden, Switzerland, United Kingdom
Lipomed

Completed

Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent Patients

Hemochromatosis

Switzerland
Pfizer

Completed

PF-06741086 Multiple Dose Study in Severe Hemophilia

Hemophilia A or B

United States, Chile, Croatia, Poland, South Africa, Switzerland
Novo Nordisk A/S

Completed

A Trial Comparing Nonacog Beta Pegol (N9-GP) and ALPROLIX® in Patients With Haemophilia B (paradigm™7)

Congenital Bleeding Disorder | Haemophilia B

United States, Switzerland, Germany
Pfizer

Completed

PF-06741086 Long-term Treatment in Severe Hemophilia

Hemophilia A or B

Poland, Switzerland, South Africa, United States, Croatia, Brazil, Chile
Novo Nordisk A/S

Completed

Comparison of the Action of Drugs in the Body and Safety of N8 and Advate® in Haemophilia A Subjects

Congenital Bleeding Disorder | Haemophilia A

Spain, Germany, Switzerland, Italy, Israel
Swiss Hemophilia Network

Recruiting

Swiss Hemophilia Registry

Hemophilia and Other Severe Bleeding Disorders

Switzerland
AstraZeneca

Completed

Prevalence of Peripheral Arterial Disease in Subject With a Moderate Risk of Cardiovascular (CV) Disease (CVD) in Primary Prevention (PANDORA)

Peripheral Arterial Disease (PAD) | Moderate Risk for Cardiovascular Disease (CVD)

France, Netherlands, Switzerland, Greece, Belgium, Italy
Vertex Pharmaceuticals Incorporated

Recruiting

Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age

Cystic Fibrosis

United Kingdom, Canada, Switzerland, Australia
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

High-risk Non-muscle Invasive Bladder Cancer

Canada, Belgium, United States, Australia, Austria, France, Germany, Greece, Hungary, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Peru, Poland, Portugal, Spain, Switzerland, Turkey, United Kingdom, China, Brazil, Colombia, ... and more
Pfizer

Terminated

A Study of Crisaborole Ointment 2%; Crisaborole Vehicle; TCS and TCI in Subjects Aged ≥ 2 Years, With Mild-moderate AD

Atopic Dermatitis

United States, Poland, Germany, United Kingdom, Italy, Sweden, Switzerland
Novartis Pharmaceuticals

Terminated

Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)

Hereditary Hemochromatosis

Belgium, France, Russian Federation, Romania, Slovakia, Spain, Switzerland
Novartis Pharmaceuticals

Completed

Clinical Outcomes and Safety: A Registry Study of Ilaris (Canakinumab) Patients (B-Confident)

Cryopyrin-associated Periodic Syndromes (CAPS) | Familial Cold Autoinflam Syn (FCAS) | Muckle-wells Syn (MWS) | Neonatal Onset Multisystem Inflam Disease (NOMID)

Switzerland, United States, Germany, Norway, Austria
Novo Nordisk A/S

Completed

Safety of NNC 0172-0000-2021 in Healthy Male Subjects and Subjects With Haemophilia A or B (Explorer 1)

Healthy | Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

Austria, Sweden, Spain, Switzerland, United Kingdom, Germany, Malaysia, Denmark, South Africa, Thailand, Italy

Clinical Trials on Genetic High Risk for Schizophrenia in Switzerland

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