Clinical Trials on Genetic Variation in Italy

Total 1242 results

University of Siena

Recruiting

Gene Editing as a Therapeutic Approach for Rett Syndrome (MECPer-3D)

Rett Syndrome

Italy
Ospedale San Raffaele

Completed

Natriuretic Effect of Amiloride in Relation to the Alpha Adducin Gene (ADD-AMI) RS4961 Variant (ADD-AMI)

Genetic Hypertension | Hypertension Essential | Salt Excess

Italy
Aileens Pharma SRL

Recruiting

Comparison of LimpiAD Cream 2.5% Plus Versus Vehicle and an Emollient in Patients With Atopic Dermatitis

Atopic Dermatitis

Italy
Azienda Ospedaliera Universitaria Senese
European Institute of Oncology; Kolfarma s.r.l. - Italy

Completed

Protective Role of Pre-/ Post-biotics on Gut Inflammation, Dysbiosis, and Life Quality in Rett Syndrome (Biotics_RTT) (Biotics_RTT)

Epilepsy | Quality of Life | Dysbiosis | Rett Syndrome

Italy
Greenpharma S.A.S.
Complife Italia S.r.l

Completed

A Controlled Study to Evaluate the Efficacy and the Tolerability of a Cosmetic Active Ingredient Intended for Subjects With Atopic Dermatitis

Mild to Moderate Atopic Dermatitis

Italy
Erydel

Completed

Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Teleangiectasia Patients (IEDAT01)

Genetic Syndrome | Nervous System Disorder

Italy
Società Italiana Talassemie ed Emoglobinopatie

Recruiting

STUDY INCIDENCE AND CHARACTERISTICS OF MALIGNANT NEOPLASIES IN PATIENTS WITH HEMOGLOBINOPATHY FOLLOWED IN ITALY (Tum001)

Malignacy, Hemoglobinopathie

Italy
Kedrion S.p.A.

Completed

Efficacy/Safety of Human Plasminogen Eye Drop in Ligneous Conjunctivitis Patients

Ligneous Conjunctivitis

United States, Italy
Unità di Medicina della Riproduzione, Italy

Completed

PGS on Blastocysts From Vitrified and Fresh Oocytes (PGSvitfreov)

Increase the Number of Blastocyst to Biopsy for Preimplantation Genetic Testing

Italy
Ariel University
Associazione Italiana Rett (AIRETT)

Not yet recruiting

Osteopathic Manipulative Treatment for Constipation in People With Rett Syndrome

Rett Syndrome

Italy
Scientific Institute San Raffaele

Recruiting

Role of Endomyocardial Biopsy and Aetiology-based Treatment in Patients With Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management (MYOCAR)

Arrhythmia | Myocarditis | Cardiomyopathies | Ventricular Arrythmia | Immunosuppression | Genetic Predisposition | Inflammatory Cardiomyopathy | Catheter Ablation | Autoimmunity

Italy
Holostem Terapie Avanzate s.r.l.
IRCCS San Raffaele; University of Modena and Reggio Emilia

Recruiting

Open-label, Pivotal Clinical Trial to Confirm Efficacy and Safety of Autologous Grafts Containing Stem Cells Genetically Modified for Epidermis Restoration in Patients With Junctional Epidermolysis Bullosa (HOLOGENE 5)

Junctional Epidermolysis Bullosa Non-Herlitz Type

France, Italy
Italfarmaco

Completed

Clinical Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients With Becker Muscular Dystrophy

Becker Muscular Dystrophy

Netherlands, Italy
Ariel University
ASST Santi Paolo e Carlo

Completed

Intensive Anti-Scoliosis Postural Intervention for Individuals With Rett Syndrome Supported by a Smartphone Application

Rett Syndrome

Italy
University of Cagliari

Unknown

Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis: a Case Control Study of the Sardinian Population

Endometriosis | Polymorphism (Genetics)

Italy
IRCCS Eugenio Medea
Associazione Italiana Rett (AIRett) O.n.l.u.s.

Completed

Tolerability of the Immersive Virtual Reality System Grail in Subjects Affected by Rett Syndrome

Rett Syndrome

Italy
Azienda Ospedaliero-Universitaria Careggi

Completed

Dietary Interventions and Butyrate Production in Behçet's Patients

Behcet Syndrome

Italy
Azienda Ospedaliero-Universitaria Careggi
University of Florence

Active, not recruiting

Cardiotoxicity Prevention in Breast Cancer Patients Treated With Anthracyclines and/or Trastuzumab (SAFE)

Breast Cancer | Cardiotoxicity

Italy
Fondazione IRCCS Policlinico San Matteo di Pavia

Recruiting

Potential Protective Role of SGLT-2 Inhibitors for Chemotherapy-induced Cardiotoxicity (PROTECT)

Breast Cancer

Italy
Azienda Ospedaliero, Universitaria Pisana

Not yet recruiting

IMPACT_BD (IMProving AdherenCe to Treatment in Behçet's Disease) (IMPACT_BD)

Behçet Disease

Italy
Azienda Ospedaliero-Universitaria Careggi

Completed

Gut Microbiota and Behcet's Syndrome: a Dietary Intervention Trial (MAMBA Study)

Behcet Syndrome

Italy
Fondazione Telethon
Ospedale San Raffaele

Completed

Gene Therapy for Wiskott-Aldrich Syndrome (TIGET-WAS)

Wiskott-Aldrich Syndrome (WAS)

Italy
Società Italiana Talassemie ed Emoglobinopatie

Recruiting

Observational Study for Patients With Hemoglobinopathies and Rare Inherited Anemia and Covid 19

Haemoglobinopathies

Italy
Azienda Policlinico Umberto I

Completed

Slowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis Pigmentosa

Retinitis Pigmentosa

Italy
University of Palermo

Recruiting

Can Gluten/Wheat or Other Foods be Responsible for FMF Attacks

Familial Mediterranean Fever | Non-celiac Gluten Sensitivity

Italy
Sanofi

Recruiting

A Study to Observe How Adolescent Patients With Severe Atopic Dermatitis Despite Less Extensive Skin Lesions (Eczema Area and Severity Index Score < 16) Respond to Dupilumab Treatment (AD-BEASCUITS)

Dermatitis Atopic

Italy
Italfarmaco

Completed

A Study to Assess Safety/Tolerability, pk, Effects on Histology, Clinical Parameters of Givinostat in Children With DMD

Duchenne Muscular Dystrophy (DMD)

Italy
ReveraGen BioPharma, Inc.
Santhera Pharmaceuticals

Recruiting

A Study to Assess Vamorolone in Becker Muscular Dystrophy (BMD)

Becker Muscular Dystrophy

United States, Italy
Azienda Ospedaliera V. Cervello

Unknown

Interferon and Ribavirin Treatment in Patients With Hemoglobinopathies (IFNRIBAHE)

Hemoglobinopathies

Italy
Astellas Pharma Inc

Completed

Study to Evaluate the Response to Treatment and Safety of 0.03% Tacrolimus (FK506) Ointment Administered in Pediatric Patients With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

Italy
IRCCS Eugenio Medea

Recruiting

Rehabilitation in Muscular Dystrophies From the Hospital Facility to the Home: Pilot Project [RIMUDI] (RIMUDI)

Muscular Dystrophies | Becker Muscular Dystrophy | Limb Girdle Muscular Dystrophy | Facio-Scapulo-Humeral Dystrophy

Italy
IRCCS San Raffaele
Fondazione Telethon

Recruiting

Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGD (XCGD-MOBI)

Chronic Granulomatous Disease X-linked (X-CGD)

Italy
Istituto Ortopedico Rizzoli

Recruiting

Functional Instability in Patients Suffering From Collagen Disease and Joint Hypermobility (VIPIA)

Collagen Diseases | Joint Hypermobility | Hypermobility Syndrome | Laxity of Ligament | Danlos Disease, Ehlers

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Biomarkers in Retinitis Pigmentosa (RPMARKER)

Retinitis Pigmentosa

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Neurovisual Function in CHARGE Syndrome

CHARGE Syndrome

Italy
Ospedale Santo Stefano
Istituto di Fisica Applicata

Completed

Laser Assisted Procedures in Penetrating Keratoplasty

Corneal Opacity | Keratoconus | Corneal Dystrophies

Italy
Monaldi Hospital

Recruiting

Subanalysis in Patients With CARDIoLAMinopathy Enrolled to REPORT-CCM Registry (CARDILAM-CCM)

Heart Failure | Lamin A/C Gene Mutation | Laminopathy

Italy
Igenomix

Completed

Clinical Value of Mosaicism Diagnosis on the Trophectoderm Biopsies (NS-MOSAICISM)

Aneuploidy | Chromosome Abnormality

Italy
Bambino Gesù Hospital and Research Institute
Autour Des Williams; Acea

Unknown

Cooperative Parent Mediated Therapy in Children With Fragile X Syndrome and Williams Syndrome

Fragile X Syndrome | Williams Syndrome

Italy
Gianni Soraru
Mario Negri Institute for Pharmacological Research

Recruiting

A Placebo-controlled Study of Clenbuterol in Spinal and Bulbar Muscular Atrophy (BetaSBMA)

Spinal and Bulbar Muscular Atrophy

Italy
Azienda Ospedaliera Città della Salute e della...

Completed

Subclinical Cardio-toxicities Evaluation With Strain Rate Echocardiography After Chemotherapy and/or Mediastinal Radiotherapy in Patient With Lymphoma (Cardiocare)

Lymphoma, Non-Hodgkin | Hodgkin Lymphoma | Toxicity, Cardiac

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Federico II University; Istituto Auxologico Italiano; Università degli Studi...

Recruiting

Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks

Beckwith-Wiedemann Syndrome

Italy
IRCCS Policlinico S. Donato
Ospedale San Raffaele

Recruiting

Validation of Quantitative Myocardial Tissue Characterization Through Non-gated CT

Covid19 | Cardiotoxicity | Cardiac Disease | Extracellular Space Alteration

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Prospective Evaluation of NfL as a Biomarker in ATTRv (NfLInATTRv)

Amyloidosis, Hereditary

Italy
Aileens Pharma SRL
Advice Pharma Group srl

Recruiting

Comparison of LimpiAD Cream 2.5% Plus Versus Its Vehicle and and a Basic Emollient in Patients With Atopic Dermatitis

Atopic Dermatitis

Italy
Università degli Studi di Brescia

Completed

PUFAs and Left Ventricular Function in Heart Failure (CS-PUFA-02)

Heart Failure | Dilated Cardiomyopathy

Italy
San Filippo Neri General Hospital

Completed

Clinical Management of Hereditary Hemochromatosis: Phlebotomy vs. Erythrocytoapheresis

Hereditary Hemochromatosis

Italy
BioMarin Pharmaceutical

Completed

Phase I/II Study of PRO044 in Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy

Belgium, Netherlands, Italy, Sweden
Istituto Auxologico Italiano

Recruiting

Biological Age in Children With GH Deficiency Undergoing Hormone Replacement Therapy (ETABIOGHD)

Growth Hormone Deficiency | Short Stature

Italy
Istituto Superiore di Sanità
Fondazione G.B. Bietti, IRCCS; Ospedale Pediatrico Bambin Gesù

Recruiting

Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models

Retinitis Pigmentosa | Macular Dystrophy | Inherited Retinal Dystrophy

Italy

Clinical Trials on Genetic Variation in Italy

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