Clinical Trials on Genetic Predisposition

Total 14739 results

J.J. Amer-Cuenca

Completed

Do Young Triathletes Have a Greater Predisposition to Suffer Running Injuries

Kinematics | Gait Retraining

Spain
Dana-Farber Cancer Institute

Active, not recruiting

Screening With Whole Body MRI For Detection Of Primary Tumors In Children And Adults With Li-Fraumeni Syndrome (LFS) And Other Cancer Predisposition Syndromes

Li-Fraumeni Syndrome

United States
University of Helsinki

Active, not recruiting

Newborn Screening for Genetic Susceptibility to Type 1 Diabetes and Celiac Disease and Prospective Follow-up Study (BABYSCREEN)

Type1diabetes | Celiac Disease

Finland
Hospital Alemão Oswaldo Cruz
Ministry of Health, Brazil; Grupo Fleury

Active, not recruiting

Impact of the Genetic Background as a Risk Factor for Atherosclerotic Cardiovascular Disease in the Brazilian Population (CV-GENES)

Cardiovascular Diseases | Stroke | Peripheral Arterial Disease | Genetic Predisposition to Disease | Acute MI

Brazil
The University of Hong Kong

Active, not recruiting

Full-scale Intervention Study: Genetic Risk Communication and Wearables

Physical Activity | Type 2 Diabetes | Genetic Predisposition to Disease | Exercise | Fitness Trackers

Hong Kong
The University of Hong Kong

Not yet recruiting

Fullscale_Intervention Study: Genetic Risk Communication in Coronary Heart Disease and Wearables

Genetic Predisposition to Disease | Coronary Heart Disease | Sedentary Time | Fitness Trackers
Assiut University

Not yet recruiting

Clinical Presentation of Genetic Disorders in Patients Attending Genetic Outpatient Clinic of Assiut University Children Hospital

Genetic Disease Clinical Presentation in Patients Attending Genetics Outpatient Clinic of Assiut University Children Hospital
International Islamic University Malaysia
University of Malaya; National University of Malaysia; International Medical... and other collaborators

Completed

Thyroid Disorders in Malaysia: A Nationwide Multicentre Study (MyEndo-Thyroid)

Hypothyroidism | Graves Disease | Hyperthyroidism | Subclinical Hypothyroidism | Iodine Deficiency | Genetic Susceptibility | Subclinical Hyperthyroidism | Hashimoto's Thyroiditis
Cliniques universitaires Saint-Luc- Université...

Recruiting

Validation of the French ATI Scale and Predisposition to Use Technological Tools in Rehabilitation.

Stroke

Belgium
Institut Claudius Regaud

Recruiting

Study of Families With an Hemopathies Predisposition Related to the DDX41 Gene. (LUCID)

DDX41 Gene Mutation

France
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Invasive Group A Streptococcus (GAS) Infection in Children: Bacterial Virulence Factors and Detection of Host Immunological and/or Genetic Factors of Predisposition to Infections (StreptoPedia)

Invasive GAS Infection

France
National Cancer Institute (NCI)

Recruiting

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

Lymphoma | Breast Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer

United States
Rigshospitalet, Denmark

Not yet recruiting

Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study (PPGL-Pred)

Head and Neck Cancer | Genetic Predisposition to Disease | Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma | Pathology | Somatic Mutation

Denmark
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
Abramson Cancer Center at Penn Medicine
Fox Chase Cancer Center; Merck Sharp & Dohme LLC; AstraZeneca; Basser Center for...

Recruiting

Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients (eReach)

Cancer

United States
University Ghent
University Hospital, Ghent

Completed

Trunkstability: a Predisposition for Armfunction

Trunk Stability

Belgium
Abramson Cancer Center at Penn Medicine

Active, not recruiting

Evaluating an Alternative Clinical Genetics Cancer Care Deliver Model

Genetic Predisposition to Disease | Prostate Cancer | Pancreas Cancer | Hereditary Cancer

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

Ovarian Cancer | Genetic Predisposition to Disease | Breast Cancer Female | Hereditary Diseases | Gene Mutation-Related Cancer | Hereditary Breast and Ovarian Cancer | Hereditary Cancer Syndrome

United States
Universidad Francisco de Vitoria
Universidad Rey Juan Carlos

Completed

Physiotherapy for Persistent COVID-19 Disease Using Aerobic Exercise

COVID-19 | Genetic Predisposition to Disease

Spain
Natera, Inc.
Ferring Pharmaceuticals

Terminated

Impact of Parental Support on Pregnancy Outcomes (IPSO) Trial- Day 3 Preimplantation Genetic Screening (PGS) With Day 5 Fresh Transfer (IPSO)

In Vitro Fertilization (IVF) | Preimplantation Genetic Diagnosis (PGD) | Preimplantation Gentic Screening (PGS)

United States
Bahria University

Completed

Ethnic Predisposition, Risk Factors & Breast Cancer Presentation. (BC)

Breast Cancer

Pakistan
IRCCS Centro Neurolesi "Bonino-Pulejo"

Recruiting

Prediction, Prevention, Predisposition: Applications in Neurology and Endocrinology (PRECUBE2022)

Dementia | Mild Cognitive Impairment

Italy
National Cancer Institute (NCI)

Recruiting

Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency

Inherited Bone Marrow Failure Syndrome | Familial Platelet Disorder With Predisposition to Myeloid Malignancies

United States
University of Pennsylvania
Memorial Sloan Kettering Cancer Center; Susan G. Komen Breast Cancer Foundation

Enrolling by invitation

Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian Cancer (PROMISE)

Ovarian Cancer | BRCA Mutation

United States
University of Pennsylvania

Not yet recruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Parkinson Disease | Alzheimer Disease | ALS | Polyneuropathies | Frontotemporal Dementia | Pheochromocytoma | Thoracic Aortic Aneurysm | Paraganglioma | Genetic Predisposition | Cardiomyopathy Non-ischemic
Henry M. Jackson Foundation for the Advancement...
National Institute of Allergy and Infectious Diseases (NIAID); Infectious Diseases...

Completed

Immunologic Predisposition of HIV Patients to Develop Methicillin-Resistant Staphylococcus Aureus (MRSA) Colonization and Infection (MRSA-2)

HIV Infections | Staphylococcal Infections

United States
King's College Hospital NHS Trust
University of Pennsylvania; Gilead Sciences; The Leeds Teaching Hospitals NHS... and other collaborators

Active, not recruiting

Genetic Determinants of Kidney Disease in People of African Ancestry With HIV (GEN-AFRICA)

Cardiovascular Diseases | Kidney Diseases | Obesity | Diabetes Mellitus | Genetic Predisposition to Disease | Kidney Injury | HIV Nephropathy

United Kingdom
University of Nebraska
National Cancer Institute (NCI); VA Nebraska Western Iowa Health Care System; Virginia Mason Hospital/Medical Center

Recruiting

Blood Markers of Early Pancreas Cancer

Diabetes Mellitus, Type 2 | PreDiabetes | Genetic Predisposition to Disease | Chronic Pancreatitis | Inherited Disease | Pancreas Cyst

United States
Barts & The London NHS Trust

Recruiting

Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA

Acromegaly | Gigantism | Familial Isolated Pituitary Adenoma | FIPA | Pituitary Adenoma Predisposition | PAP

United Kingdom
Institut Claudius Regaud
Ligue contre le cancer, France

Recruiting

Male breAsT cAncer preDisposition Factor (MATADOR)

Breast Cancer

France
Banner Health
Mayo Clinic

Recruiting

APOE in the Predisposition to, Protection From, and Prevention of Alzheimer's Disease

Alzheimer Disease

United States
London North West Healthcare NHS Trust

Not yet recruiting

PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome (PSYLIVED)

Lynch Syndrome | Polyposis Syndrome, Hereditary Mixed, 1 | Polyposis Syndrome, Hereditary Mixed, 2

United Kingdom
Massachusetts General Hospital

Recruiting

Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)

Lynch Syndrome | Genetic Predisposition to Disease | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Neoplasm | ATM Gene Mutation | MMR Mutation

United States
Instituto de Investigación Hospital Universitario...
Crazy Science & Business S.L.

Recruiting

Study for the Validation of a New Biomarker to Determine Predisposition to Infections in Patients With Acute Myocardial Infarction.

Infections in Acute Myocardial Infarction Patients

Spain
Nantes University Hospital

Active, not recruiting

IDEntification of New Predisposition Genes in Differentiated THYroid Cancer (IDENTHY-K)

Differentiated Thyroid Cancer | Thyroid Cancer, Nonmedullary

France
Nicklaus Children's Hospital f/k/a Miami Children...
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

Diagnostic Odyssey: Whole Genome Sequencing (WGS)

Genetic Disease | Genetic Syndrome

United States
Children's Hospital Medical Center, Cincinnati
University of Cincinnati

Recruiting

Engaging Adolescents in Decisions About Return of Genomic Research Results

Adolescent | Knowledge, Attitudes, Practice | Shared Decision Making | Genetic Testing | Genetic Screening | Genetic Change

United States
Central Hospital, Nancy, France

Completed

Reinterpretation of CNV With Unknown Significance: a 5-year Retrospective Analysis (ReAC)

Genetic Disease | CNV | Genetic Counseling | Array CGH

France
University of Illinois College of Medicine at Peoria
Rady Children's Institute of Genomic Medicine

Active, not recruiting

Utility of Rapid Whole Genome Sequencing in the NICU: A Pilot Study

Genetic Disease | Genetic Syndrome

United States
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

An Adaptive Clinical Trial of BeginNGS Newborn Screening for Hundreds of Genetic Diseases by Genome Sequencing (BeginNGS)

Genetic Disease

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Technological Development and Clinical Parallel Testing of PGT-G

Genetic Disease

China
Arcensus GmbH

Recruiting

Metabolic FingerPrinting (MetaPrint)

Genetic Disease

Albania, Pakistan
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

DNA Sequencing in Clinical Practice, Mayo Clinic Health Tapestry Study

Genetic Disorder

United States
Kevin Bruce

Not yet recruiting

Developing Protocols for Modelling of Genetic Diseases Using Induced Pluripotent Stem Cells

Genetic Disease
Brigham and Women's Hospital

Withdrawn

Virtual Visits for Results Disclosure

Genetic Disease
Vanderbilt University Medical Center

Recruiting

The Electronic Medical Records and GEnomics (eMERGE) Network Genomic Risk Assessment (eMERGE)

Genetic Disease

United States
Illumina, Inc.
Medical College of Wisconsin

Active, not recruiting

iKnow: A Prospective Study to Evaluate the Use of Multi-omics in Multi-System, Early Onset Disorders (iKnow)

Genetic Disease

United States
Rady Pediatric Genomics & Systems Medicine Institute

Active, not recruiting

Newborn Genomic Sequencing Pilot Study

Genetic Disease

United States
Igentify Ltd
Sheba Medical Center

Unknown

The Use of Digital Genetic Assistant (DGA) for Expanded Carrier Screening

Genetic Disease
Maastricht University Medical Center

Recruiting

Biobank Clinical Genetics Maastricht (KG01) (KG01)

Genetic Disease

Netherlands

Clinical Trials on Genetic Predisposition

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Drug Interventions

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